Abstract：
OBJECTIVE:To present early outcome data from patients treated for invasive penile cancers with organ-sparing surgery, as the treatment of such malignancies has traditionally either been amputative surgery or radical radiotherapy, both associated with significant physical and psychosexual morbidity. PATIENTS AND METHODS:A consecutive series of patients referred over a 3-year period for the treatment of penile malignancy were analysed prospectively. After clinical staging and grading, those patients requiring surgery were offered either a glans-preserving or a glans-removing procedure. RESULTS:Of the 78 patients referred, 49 required surgery, with penile-preserving procedures in 39 of them; 32 were newly diagnosed tumours and seven were recurrences after radiotherapy. The tumour grade and stage were G1 in 11, G2 in 17 and G3 in 10 (one had melanoma and was not graded); and Ta in two, T1 in 19, T2 in 17 and T3 in one. The mean follow-up was 16 months, with nine patients followed for > or = 2 years. Complications included two patients who required immediate revisional surgery for positive resection margins, and one with radio-necrosis. One patient who had a glans-preserving procedure developed a recurrence, whereas none of those who had the glans removed did so. CONCLUSION:With careful patient selection and meticulous follow-up, most patients with invasive penile carcinoma can be offered penile-preserving surgery.
journal_name
BJU Intjournal_title
BJU internationalauthors
Pietrzak P,Corbishley C,Watkin Ndoi
10.1111/j.1464-410X.2004.05153.xkeywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
1253-7issue
9eissn
1464-4096issn
1464-410Xpii
BJU5153journal_volume
94pub_type
杂志文章abstract：OBJECTIVE:To review long-term oncological and functional outcomes of testicular-sparing surgery (TSS) in men presenting with bilateral or monorchide testicular tumours at one of five reference centres for testicular neoplasm and infertility. PATIENTS AND METHODS:We review 25 cases of bilateral synchrone and metachrone...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1111/bju.12549
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abstract：OBJECTIVE:To ascertain the urological complications of coitus, as the proximity of the lower urinary tract to the organs of coitus exposes the tract to coital trauma. MATERIALS AND METHODS:Medline was searched from 1966 to 2000 to identify reports on coital injuries. Publications and relevant references were retrieved...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1046/j.1464-4096.2001.01458.x
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVES:To describe the natural history of prostate cancer in men who experience a second biochemical recurrence (BCR) after salvage radiotherapy (SRT) after prostatectomy. PATIENTS AND METHODS:After undergoing SRT at one of two institutions between 1986 and 2013, 286 patients experienced a second BCR, defined as t...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1111/bju.13926
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To define changes in the clinical pathway for open radical retropubic prostatectomy (RRP) and to determine their impact on patient care under the indirect influence of minimally invasive prostatectomy after implementing robotically assisted laparoscopic prostatectomy (RALP) at our institution and modifying th...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05993.x
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVE:To characterize the clinical outcomes of androgen deprivation therapy (ADT) as the sole therapy for localized prostate cancer, and to determine independent predictors of disease progression, as recent studies indicate an increasing use of ADT. PATIENTS AND METHODS:The records of all patients with cT1-4NXM0 a...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05674.x
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:To assess the potential of p21 as a gene therapy treatment for prostate cancer, by introducing p21 into both androgen-dependent (AD) and -independent (AI) human prostate cancer cell lines via a recombinant adenoviral vector, Ad5CMV-p21, carrying human p21 cDNA. MATERIALS AND METHODS:The LNCaP, DU145 and PC-3...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2003.04318.x
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVE:To report our experience with laparoscopic robotic-assisted management of pelvi-ureteric junction obstruction (PUJO) in patients with horseshoe kidneys. PATIENTS AND METHODS:Between January 2002 and May 2003, two men and a woman with horseshoe kidneys (mean age 44.6 years) had laparoscopic dismembered pyelop...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.05967.x
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVE:• To systematically review and compare the economic burden of open radical cystectomy (ORC) vs robot-assisted laparoscopic radical cystectomy (RALRC) with pelvic lymph node dissection and urinary diversion. PATIENTS AND METHODS:• A Medline search was conducted to identify English language articles regarding ...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1111/j.1464-410X.2011.10468.x
更新日期：2011-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.08262.x
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To assess the clinical pattern of progression and prostate-specific antigen doubling time (PSA-DT) after exposure to docetaxel-based chemotherapy in patients with androgen-independent prostate cancer (AIPC). PATIENTS AND METHODS:Fifty-five patients received docetaxel-based chemotherapy; data were collected r...
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pub_type： 杂志文章,多中心研究
doi：10.1111/j.1464-410X.2007.07037.x
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVES:To determine the feasibility and efficacy of suicide-gene therapy using adenovirus (Ad)-mediated herpes simplex virus thymidine kinase (HSV-TK) and the prodrug acyclovir, and to evaluate changes in the biological phenotype for tumour cell proliferative activity after suicide-gene therapy in animal models of ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2000.00516.x
更新日期：2000-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/bju.12489
更新日期：2016-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/j.1464-410X.2011.10526.x
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:To present the results of endopyelotomy using endoluminal ultrasonography (EUS) to identify crossing vessels, as the success rates of endopyelotomy are generally lower than pyeloplasty, especially in patients with crossing vessels. PATIENTS AND METHODS:Forty-one consecutive patients who underwent EUS before ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2003.04103.x
更新日期：2003-03-01 00:00:00
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pub_type： 杂志文章,meta分析
doi：10.1111/j.1464-410X.2005.05454.x
更新日期：2005-05-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00254.x
更新日期：1999-10-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06515.x
更新日期：2007-01-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.07198.x
更新日期：2008-01-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2000.00771.x
更新日期：2000-09-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-4096.2001.01562.x
更新日期：2002-03-01 00:00:00
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journal_title：BJU international
pub_type： 临床试验,杂志文章
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更新日期：2005-02-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2003.04222.x
更新日期：2003-06-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05408.x
更新日期：2005-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between the levels of glycosylated haemoglobin (HbA1c) and the severity of erectile dysfunction (ED) in men with diabetes mellitus (DM). PATIENTS AND METHODS:This cross-sectional study included sexually active men with a diagnosis of DM attending a urological medical centre from J...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05349.x
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:To assess the clinical effect of the 'prostatic urethral lift' (PUL) on lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) through a crossover design study. PATIENTS AND METHODS:Men aged ≥ 50 years with an International Prostate Symptom Score of ≥ 13, a maximum urinary flo...
journal_title：BJU international
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/bju.12540
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To identify the likelihood of finding one or more positive lymph nodes (LNs) according to the number of LNs removed at radical cystectomy (RC), as the number of LNs removed affects disease progression and survival after RC. PATIENTS AND METHODS:Between 1984 and 2003, 731 assessable patients had RC and bilate...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1464-410X.2008.08212.x
更新日期：2009-05-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2012.11230.x
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:To assess the use of sodium pentosan polysulphate (SPP) for haemorrhagic cystitis (HC), a potentially life-threatening side-effect in patients treated with pelvic radiotherapy or cyclophosphamide, and which can be difficult to manage as patients often have significant comorbidity. PATIENTS AND METHODS:Betwee...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2004.05044.x
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of zoledronic acid (ZA) in osteoporotic patients with prostate cancer receiving either luteinizing hormone-releasing hormone agonists (LHRHA, which accelerate bone loss) or bicalutamide (which preserves bone mineral density, BMD) as androgen-deprivation therapy is the mainstay of trea...
journal_title：BJU international
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1464-410X.2009.08956.x
更新日期：2010-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the biological effects of selective cyclooxygenase-2 inhibition on prostate tissue in patients undergoing radical prostatectomy (RP). PATIENTS AND METHODS:Patients with localised prostate cancer were randomised to receive either celecoxib 400 mg twice daily or placebo for 4 weeks before RP. Speci...
journal_title：BJU international
pub_type： 杂志文章,随机对照试验
doi：10.1111/bju.13612
更新日期：2017-05-01 00:00:00
