Glycemic index, glycemic load and risk of prostate cancer.

abstract：:CA 50 is a new tumor marker based on a monoclonal antibody (MAb) against a human colorectal carcinoma cell line. The CA 50 antigen is similar, but not identical, to the tumor marker CA 19-9. The serum concentrations of CA 50 were measured by an immunoradiometric assay (CA 50 IRMA) in 95 patients with pancreatic cancer...

journal_title：International journal of cancer

authors： Haglund C,Kuusela P,Jalanko H,Roberts PJ

更新日期：1987-04-15 00:00:00

abstract：:The Eph receptor A2 (EphA2) is overexpressed in a range of human epithelial cancers, a phenotype that is associated with cancer cell proliferation, progression and angiogenesis. Mouse models of mammary neoplasia have confirmed the role of EphA2 as mice carrying a knockout allele of EphA2 were resistant to breast cance...

journal_title：International journal of cancer

authors： Bogan C,Chen J,O'Sullivan MG,Cormier RT

更新日期：2009-03-15 00:00:00

abstract：:The c-KIT protooncogene encodes a tyrosine kinase receptor, KIT, that is expressed in many normal and cancerous tissues. In this study, we have examined the expression of c-KIT and its ligand, stem cell factor (SCF), in human epithelial ovarian tumors, in normal ovaries and in cultured ovarian surface epithelium (OSE)...

journal_title：International journal of cancer

authors： Tonary AM,Macdonald EA,Faught W,Senterman MK,Vanderhyden BC

更新日期：2000-05-20 00:00:00

abstract：:We applied a strategy that utilized a combination of systematic gene expression analysis with various tissues and immunological detection with sera from melanoma patients to identify melanoma antigens expressed preferentially in melanoma and melanocytes. We selected 101 genes by comparing cDNA profiles obtained by Gen...

journal_title：International journal of cancer

authors： Inozume T,Matsuzaki Y,Kurihara S,Fujita T,Yamamoto A,Aburatani H,Shimada S,Kawakami Y

更新日期：2005-03-20 00:00:00

abstract：:Statins are widely used for the treatment of hypercholesterolemia. However, their inhibitory action on HMG-CoA reductase also results in the depletion of intermediate biosynthetic products, which importantly contribute to cell proliferation. The aim of the present study was to compare the effects of the individual com...

journal_title：International journal of cancer

authors： Gbelcová H,Lenícek M,Zelenka J,Knejzlík Z,Dvoráková G,Zadinová M,Poucková P,Kudla M,Balaz P,Ruml T,Vítek L

更新日期：2008-03-15 00:00:00

abstract：:In addition to antiviral effects, Type I interferons (IFN) have potent antiproliferative and immunomodulatory activities. Because of these properties IFNs have been evaluated as therapeutics for the treatment of a number of human diseases, including cancer. Currently, IFNs have been shown to be efficacious for the tre...

journal_title：International journal of cancer

authors： Wagner TC,Velichko S,Chesney SK,Biroc S,Harde D,Vogel D,Croze E

更新日期：2004-08-10 00:00:00

abstract：:Infection of normal human melanocyte and nevus cultures with an adenovirus 12-Simian Virus 40 hybrid virus (Ad12-SV40) produced transformed cells that expressed SV40-T antigen. The Ad12-SV40 cells exhibited rapid cell proliferation to high cell densities and efficient growth in soft agar, but none of 15 transformed me...

journal_title：International journal of cancer

authors： Jambrosic J,Mancianti ML,Ricciardi R,Sela BA,Koprowski H,Herlyn M

更新日期：1989-12-15 00:00:00

abstract：:Rapid tumor growth and metastasis are 2 major problems associated with treatment of malignant melanoma. Therefore, drugs that can intervene these processes are of clinical importance. Pentoxifylline (PTX), a methyl xanthine derivative, has been shown to inhibit B16F10 melanoma tumor growth and metastasis. We hypothesi...

journal_title：International journal of cancer

authors： Dua P,Ingle A,Gude RP

更新日期：2007-10-01 00:00:00

abstract：:The irregular vasculature and high interstitial pressure of solid tumors hinder the delivery of cytotoxic agents to cancer cells. As a consequence, the doses of chemotherapy necessary to achieve complete tumor eradication are associated with unacceptably high toxicities. The selective thrombosis of tumor blood vessels...

journal_title：International journal of cancer

authors： Fabbrini M,Trachsel E,Soldani P,Bindi S,Alessi P,Bracci L,Kosmehl H,Zardi L,Neri D,Neri P

更新日期：2006-04-01 00:00:00

abstract：:Animal and experimental data suggest that anti-Müllerian hormone (AMH) serves as a marker of ovarian reserve and inhibits the growth of ovarian tumors. However, few epidemiologic studies have examined the association between AMH and ovarian cancer risk. We conducted a nested case-control study of 302 ovarian cancer ca...

journal_title：International journal of cancer

authors： Jung S,Allen N,Arslan AA,Baglietto L,Barricarte A,Brinton LA,Egleston BL,Falk RT,Fortner RT,Helzlsouer KJ,Gao Y,Idahl A,Kaaks R,Krogh V,Merritt MA,Lundin E,Onland-Moret NC,Rinaldi S,Schock H,Shu XO,Sluss PM,Staa

更新日期：2018-01-15 00:00:00

abstract：:Tamoxifen is an important selective estrogen receptor (ER) modulator for treatment of steroid hormone positive breast cancer. In addition to the beneficial effect, tamoxifen is one risk factor for endometrial carcinoma (EnCa) development. We hypothesized that, (1) dysregulation of gene expression and protein phosphory...

journal_title：International journal of cancer

authors： Strissel PL,Ellmann S,Loprich E,Thiel F,Fasching PA,Stiegler E,Hartmann A,Beckmann MW,Strick R

更新日期：2008-12-15 00:00:00

abstract：:We describe the anatomic and histologic presentation and prognosis of non-Hodgkin's lymphoma (NHL) among people with AIDS (PWA) and determine their contribution to the NHL burden. We linked AIDS and cancer registries in selected areas of the United States and compared NHL sites and histologies in PWA and non-PWA, afte...

journal_title：International journal of cancer

authors： Coté TR,Biggar RJ,Rosenberg PS,Devesa SS,Percy C,Yellin FJ,Lemp G,Hardy C,Geodert JJ,Blattner WA

更新日期：1997-11-27 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATLL). It has been postulated that ATLL cells might act as regulatory T cells (T(regs)) which, in common with ATLL cells, express both CD25 and FoxP3, and so contribute to the severe immune suppression typical of ATLL....

journal_title：International journal of cancer

authors： Toulza F,Nosaka K,Takiguchi M,Pagliuca T,Mitsuya H,Tanaka Y,Taylor GP,Bangham CR

更新日期：2009-11-15 00:00:00

abstract：:We assessed whether split dosing with the methylating agent DTIC is an effective strategy for inactivating the DNA repair protein O6-alkylguanine DNA-ATase in order to decrease tumour resistance to BCNU. ATase levels in PBMCs were used as a surrogate for tumour ATase depletion to determine whether this correlated with...

journal_title：International journal of cancer

authors： Clemons M,Ranson M,Margison JM,El Teraifi H,Griffiths A,Kelly J,Morris CQ,Howell A,Margison GP

更新日期：2003-02-20 00:00:00

abstract：:The physiological stress response to surgery promotes wound healing and functional recovery and includes the activation of neural, inflammatory and proangiogenic signaling pathways. Paradoxically, the same pathways also promote metastatic spread and growth of residual cancer. Human and animal studies show that cancer ...

journal_title：International journal of cancer

authors： Raskov H,Orhan A,Salanti A,Gögenur I

更新日期：2020-06-15 00:00:00

abstract：:Malignant glioma is one of the most aggressive cancers. For the development of effective therapeutic strategies against such malignant diseases, elucidation of molecular targets is necessary. We found that inactivated Sendai virus particle (HVJ-E) induced extensive cell death in the human glioblastoma cell line U251MG...

journal_title：International journal of cancer

authors： Tanaka M,Shimbo T,Kikuchi Y,Matsuda M,Kaneda Y

更新日期：2010-04-15 00:00:00

abstract：:Loss of heterozygosity (LOH) is an important event of tumorigenesis. In gastric cancer, we found a novel region of LOH in chromosome 9q having about 800 kb deletions at 9q31.1. The microsatellite marker D9S938 in that region exhibiting the highest LOH frequency, 56.5%. In addition, the LOH at 9q31.1 did not show any r...

journal_title：International journal of cancer

authors： Kakinuma N,Kohu K,Sato M,Yamada T,Nakajima M,Akiyama T,Ohwada S,Shibanaka Y

更新日期：2004-03-01 00:00:00

abstract：:Condylomata acuminata have been shown to increase the risk of anogenital cancers. However, previous studies have been of limited sample size and/or short follow-up duration, which prevent precise estimates of long-term excess risk, especially for specific cancer sites. We estimated the risk of specific cancers in a la...

journal_title：International journal of cancer

authors： Nordenvall C,Chang ET,Adami HO,Ye W

更新日期：2006-08-15 00:00:00

abstract：:The red bone marrow (BM) is an important indicator organ of hematogenous micrometastatic spread of carcinomas. Characterization of biological properties specific for BM micrometastatic cells, however, is technically challenging due to the limited number of target cells usually available for the purpose. This report pr...

journal_title：International journal of cancer

authors： Ree AH,Engebraaten O,Hovig E,Fodstad Ø

更新日期：2002-01-01 00:00:00

abstract：:Gene transfer is an attractive approach to fight cancer by targeting cancer cells or their vasculature. Our study reports the inhibition of tumor growth and angiogenesis by a nonviral method using dendrimers associated with 36-mer anionic oligomers (ON36) for delivering angiostatin (Kringle 1-3) and tissue inhibitor o...

journal_title：International journal of cancer

authors： Vincent L,Varet J,Pille JY,Bompais H,Opolon P,Maksimenko A,Malvy C,Mirshahi M,Lu H,Vannier JP,Soria C,Li H

更新日期：2003-06-20 00:00:00

abstract：:Medulloblastoma is a primitive neuroectodermal tumor of the cerebellum with poorly understood pathogenesis. Previous studies have reported loss of heterozygosity (LOH) on chromosome arms 17p, 11p and 9q and cytogenetic abnormalities of chromosome 1 in medulloblastoma. We have used the polymerase chain reaction to ampl...

journal_title：International journal of cancer

authors： Kraus JA,Koch A,Albrecht S,Von Deimling A,Wiestler OD,Pietsch T

更新日期：1996-07-03 00:00:00

abstract：:Expression of the candidate metastasis-suppressor gene nm23-H1 has been shown to correlate inversely with metastatic potential in some human tumors, but not in all. Until now, few studies have been carried out on the activity of the homologous nm23-H2 gene in human cancer. No nm23 transcription studies exist for human...

journal_title：International journal of cancer

authors： Engel M,Theisinger B,Seib T,Seitz G,Huwer H,Zang KD,Welter C,Dooley S

更新日期：1993-09-30 00:00:00

abstract：:Protocadherin 10 (PCDH10), a novel tumor suppressor gene in human cancers, is located in a common deleted region at chromosome 4q28 in colorectal cancer (CRC). This study aimed to ascertain the genetic loss of PCDH10 and its clinical relevance in CRC and to explore the tumor suppressor function of PCDH10. The genetic ...

journal_title：International journal of cancer

authors： Jao TM,Tsai MH,Lio HY,Weng WT,Chen CC,Tzeng ST,Chang CY,Lai YC,Yen SJ,Yu SL,Yang YC

更新日期：2014-12-01 00:00:00

abstract：:The numbers of new cancer cases in 16 common sites occurring in 1980 have been estimated for 24 areas of the world for which the United Nations produces population estimates. For the world as a whole, the total number of new cases was 6.35 million, almost exactly evenly divided between the developed and developing cou...

journal_title：International journal of cancer

authors： Parkin DM,Läärä E,Muir CS

更新日期：1988-02-15 00:00:00

abstract：:Microtubule-targeted drugs are now indispensable for the therapy of various cancer types worldwide. In this article, we report MT119 [6-[2-(4-methoxyphenyl) -ethyl]-9-[(pyridine-3-ylmethyl)amino]pyrido[2',1':2,3]imida-zo[4,5-c]isoquinolin-5(6H)-one] as a new microtubule-targeted agent. MT119 inhibited tubulin polymeri...

journal_title：International journal of cancer

authors： Zhang Z,Meng T,Yang N,Wang W,Xiong B,Chen Y,Ma L,Shen J,Miao ZH,Ding J

更新日期：2011-07-01 00:00:00

abstract：:Analysis of the length of circulating DNA in plasma has been reported as a marker for solid tumor detection. We assessed the sensitivity and specificity of increased plasma DNA length to identify patients with head and neck squamous cell carcinoma (HNSCC) and monitor posttreatment disease status. Fifty-eight HNSCC pat...

journal_title：International journal of cancer

authors： Jiang WW,Zahurak M,Goldenberg D,Milman Y,Park HL,Westra WH,Koch W,Sidransky D,Califano J

更新日期：2006-12-01 00:00:00

abstract：:Folate receptor-alpha (FR-alpha) is generally over-expressed in non-mucinous human ovarian carcinomas. The meaning of FR-alpha over-expression and its role in the 5-methyltetrahydrofolic acid (N5-CH3-H4PteGlu) transport in such tumors is not clear, especially compared with the reduced folate carrier (RFC), the other k...

journal_title：International journal of cancer

authors： Corona G,Giannini F,Fabris M,Toffoli G,Boiocchi M

更新日期：1998-01-05 00:00:00

abstract：:Promoter hypermethylation of various tumor-related genes is extremely frequent in gastric carcinoma (GC) associated with Epstein-Barr virus (EBV). To investigate the significance of the promoter methylation in this type of GC, we examined the methylation densities of the promoter regions of p14ARF and p16INK4A in EBV-...

journal_title：International journal of cancer

authors： Sakuma K,Chong JM,Sudo M,Ushiku T,Inoue Y,Shibahara J,Uozaki H,Nagai H,Fukayama M

更新日期：2004-11-01 00:00:00

abstract：:We analyzed the number of circulating tumor cells (CTCs) and Epstein-Barr virus DNA (EBV DNA) for diagnosis, monitoring and prognosis of patients with metastatic nasopharyngeal carcinoma (mNPC). The levels of CTCs and EBV DNA were measured at baseline and after first-line chemotherapy in 148 mNPC patients prospectivel...

journal_title：International journal of cancer

authors： You R,Liu YP,Lin M,Huang PY,Tang LQ,Zhang YN,Pan Y,Liu WL,Guo WB,Zou X,Zhao KM,Kang T,Liu LZ,Lin AH,Hong MH,Mai HQ,Zeng MS,Chen MY

更新日期：2019-11-15 00:00:00

abstract：:gamma-L-glutaminyl-4-hydroxy-3-iodobenzene (I-GHB), a novel iodinated analog of gamma-L-glutaminyl-4-hydroxybenzene (GHB), demonstrates greater anti-tumor activity in human and in murine melanoma cell lines. These phenolic amides are substrates for gamma-glutamyltranspeptidase (GGTP; E.C. 2.3.2.2), a cell-membrane-ass...

journal_title：International journal of cancer

authors： Prezioso JA,Hughey RP,Wang N,Damodaran KM,Bloomer WD

更新日期：1994-03-15 00:00:00