Abstract：
OBJECTIVE:To examine the effectiveness of subinguinal microsurgical varicocelectomy in the treatment of persistent or recurrent varicocele. DESIGN:Retrospective chart review. SETTING:Urban, tertiary care, academic teaching hospital. PATIENT(S):Fifty-four men who presented for treatment of persistent or recurrent varicocele. INTERVENTION(S):A single surgeon using an artery and lymphatic sparing subinguinal microsurgical technique with delivery of the testis repaired all varicocele. MAIN OUTCOME MEASURE(S):Preoperative to postoperative changes in semen parameters (volume of ejaculate, sperm concentration, percent motility, percent morphologically normal sperm, total motile sperm concentration), serum hormone levels, and testicular volume. Pregnancy rates and surgical complications were documented. RESULT(S):Postoperative mean serum T and mean testicular volume increased significantly from prevaricocelectomy levels. Median sperm concentration, percent motility, and total motile sperm per ejaculate improved significantly following recurrent varicocelectomy. Among patients with follow-up over 24 weeks (65%, 35 out of 54), the overall pregnancy rate was 40% (14 out of 35), including 23% (8 out of 35) of pregnancies achieved through natural intercourse, 9% (3 out of 35) with IVF/intracytoplasmic sperm injection, and 9% (3 out of 35) with IUI. Complications such as hydrocele, hematoma, wound infection, and testicular atrophy were not observed during the follow-up period. CONCLUSION(S):Treatment of persistent or recurrent varicocele using an artery and lymphatic sparing subinguinal microsurgical technique with delivery of the testis improves semen parameters, serum T levels, and testicular volume from preoperative levels without a significant risk of postoperative complications.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Grober ED,Chan PT,Zini A,Goldstein Mdoi
10.1016/j.fertnstert.2004.03.028keywords:
subject
Has Abstractpub_date
2004-09-01 00:00:00pages
718-22issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(04)00905-7journal_volume
82pub_type
杂志文章abstract：OBJECTIVE:To compare saline infusion sonography (SIS) with gel instillation sonography (GIS) in terms of feasibility and diagnostic accuracy. DESIGN:Prospective cohort study. SETTING:Leuven University bleeding clinic. PATIENT(S):A total of 804 patients: two consecutive cohorts of 402 women undergoing SIS or GIS. IN...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2010.04.074
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To investigate the possibility of genetic contribution of CYP1A1, CYP19, GSTM1, and GSTT1 polymorphisms to endometriosis. DESIGN:Genetic polymorphism analysis. SETTING:Case-control study. PATIENT(S):A group of 275 women with sporadic endometriosis was compared with a group of 346 fertile, endometriosis-fre...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)04817-3
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:To review the definition and diagnosis of interstitial and heterotopic interstitial pregnancy and to evaluate the conservative management of these conditions. DESIGN:A MEDLINE computer search was used to identify relevant studies. The mean values for the duration of amenorrhea, serum beta-hCG level, size of ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(99)00242-3
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVE:To investigate the expression pattern of two oocyte-secreted factors-growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BM15)-during oocyte maturation in women with polycystic ovary syndrome (PCOS) and in controls and to evaluate the expression differences in oocytes between the two gro...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.05.036
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:To examine the effects of different thermodynamic control systems on the temperature stability of human eggs during in vitro manipulation, with the integrity of meiotic spindles imaged using the LC-PolScope (Cambridge Research & Instrumentation, Inc., Woburn, MA). DESIGN:We performed intracytoplasmic sperm i...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03117-5
更新日期：2002-06-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of letrozole in patients undergoing superovulation with gonadotropins and IUI. DESIGN:Retrospective analysis. SETTING:Academic teaching hospital. PATIENT(S):Women younger than 40 years of age with patent fallopian tubes and infertility of more than 1 year in duration who were und...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.03.001
更新日期：2003-12-01 00:00:00
abstract：:The histologic appearance of the testes of men exposed to chronic gonadotropin-releasing hormone agonist (GnRH-A) therapy has not been previously documented. Herein, we report on the histologic features of the testes of four patients with disseminated prostatic carcinoma who received at least 1 year of daily treatment...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48205-1
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To investigate the localization of tenascin expression in the endometrium of women without endometriosis and in endometriotic implants, and to determine the in vitro regulation of tenascin by E(2) in these tissues. DESIGN:Experimental laboratory study. SETTING:University medical center. PATIENT(S):Reproduc...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.05.028
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:To understand the barriers that serodiscordant couples with human immunodeficiency virus (HIV) face in accessing services for risk reduction and infertility using assisted reproductive technology (ART). DESIGN:Two-arm cross-sectional telephone "secret shopper" study. SETTING:Infertility clinics designated b...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2017.11.039
更新日期：2018-03-01 00:00:00
abstract：:Evidence from more than 14,000 reproductive histories in the Collaborative Perinatal Project of the National Institute of Neurological and Communicative Disorders and Stroke indicates that the risk of spontaneous abortion increases considerably with gravidity. Maternal age, memory errors, and sampling bias related to ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of Interceed(TC7) (Johnson and Johnson, New Brunswick, NJ) in the prevention of postoperative adhesions in a rabbit uterine horn model. Interceed(TC7) was tested in the presence and absence of absorbable suture. DESIGN, SETTING, PARTICIPANTS:Forty-one New Zealand white rabbits h...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Past practices of Natural Family Planning (NFP) have included such techniques as: 1) calendar rhythm in which a constant mathematical relationship was calculated between the day of ovulation and the beginning of the succeeding menstrual period, 2) temperature rhythm in which sexual intercourse is permitted by observi...
journal_title：Fertility and sterility
pub_type： 社论
doi：10.1016/s0015-0282(16)45849-8
更新日期：1981-11-01 00:00:00
abstract：:Semen analysis results obtained by a recently developed semi-automated Autosperm system (Amsaten N.V.S.A. Corp., De Pinte, Belgium) were compared with those obtained by the conventional, time-exposure photomicrographic, and automated CellSoft system (Cryo Resources Inc., New York, NY) analyses. The Autosperm system ei...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVES:To test the hypothesis that fertility is reduced in baboons with endometriosis. DESIGN:Prospective controlled follow-up study. SETTING:Institute of Primate Research, Nairobi Kenya. SUBJECTS:Seventy-one baboons, including 34 controls (normal pelvis) and 37 animals with histologically proven endometriosis (...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVE:To determine the feasibility of performing in vivo magnetic resonance elastography (MRE) for uterine leiomyoma. DESIGN:Pilot study. SETTING:Academic medical center. PATIENT(S):Six subjects planning surgical excision of uterine leiomyomas. INTERVENTION(S):MRE before planned surgery. MAIN OUTCOME MEASURE(S...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2010.06.004
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To summarize the available evidence for the efficacy of various treatments for unexplained infertility. DESIGN:Systematic review. SETTING:Not applicable. PATIENT(S):Patients aged 18-40 years with unexplained infertility. INTERVENTION(S):Clomiphene citrate, letrozole, timed intercourse, IUI, gonadotropins,...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2016.02.001
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:To examine all case reports and studies of empty follicle syndrome (EFS) that have been published since the condition was first reported, in an attempt to identify trends or common features that may expose possible risk or causative factors. DESIGN:Systematic review of all available literature obtained from...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.fertnstert.2007.07.1312
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of reproductive history on the outcome of different procedures in assisted reproductive technologies (ART) comparing IVF, ICSI, and cryopreserved embryo transfer (CPE). DESIGN:Prospective registration of ART cycles and their outcomes. SETTING:One hundred three reproductive programs in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)00760-x
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To determine whether the use of GnRH antagonist in cycles converted from ovulation induction-IUI to IVF affects cycle outcome and pregnancy rates. DESIGN:Retrospective cohort study. SETTING:Academic research institution. PATIENT(S):One hundred eighty-two consecutive patients with ovulation induction-IUI to...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.01.109
更新日期：2010-02-01 00:00:00
abstract：:A patient with Nelson's syndrome whose pregnancy was complicated by symptomatic enlargement of an ACTH-producing pituitary tumor was described. Emergency ablative surgery was performed with successful outcomes for both mother and infant. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48932-6
更新日期：1985-10-01 00:00:00
abstract：OBJECTIVE:To compare ovarian performance and hormonal levels, after ovulation induction, in patients with isolated hypogonadotropic hypogonadism, using two different gonadotropin drugs. DESIGN:Patients were treated during consecutive cycles, using the same stimulation protocol, with human menopausal gonadotropin (hMG)...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)54715-3
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVE:To analyze relationships between serum free fatty acid (FFA) concentrations and pregnancy. DESIGN:Prospective cohort. SETTING:University hospital. PATIENT(S):Ninety-one women undergoing IVF. INTERVENTION(S):Serum was analyzed for total and specific serum FFAs, including myristic, palmitic, stearic, oleic,...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.07.1115
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To evaluate FOXP3 polymorphisms (rs3761549, rs3761548, rs2232368, rs2232366, and rs2280883) in a group of infertile women with and without endometriosis and controls. DESIGN:Case control study. SETTING:Human Reproduction Outpatient Clinic of Faculdade de Medicina do ABC. PATIENT(S):The study groups were 17...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.03.033
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the extent to which test accuracy studies published in two leading reproductive medicine journals in the years 1999 and 2004 adhered to the Standards for Reporting of Diagnostic Accuracy (STARD) initiative parameters, and to explore whether the introduction of the STARD statement has led to an imp...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.050
更新日期：2006-11-01 00:00:00
abstract：STUDY OBJECTIVE:To determine the extent to which increasing doses of exogenous testosterone (T) administered via Silastic implants can restore spermatogenesis and fertility to rats made azoospermic by active immunization against gonadotropin-releasing hormone (GnRH). DESIGN:Male rats were made azoospermic by active im...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55192-9
更新日期：1992-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the risk that nulliparity poses to the outcome of twin pregnancies, an issue that gained importance due to the rise of twin gestations following assisted reproduction interventions. DESIGN:A prospective cohort study. SETTING AND PATIENT(S):Between January 1, 2004, and January 7, 2008, we prospec...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.12.035
更新日期：2010-04-01 00:00:00
abstract：:Chronic GnRH antagonist therapy produces enhanced gonadotrope responsiveness to supraphysiologic stimuli despite the lack of any measurable suppression of gonadotropin levels. This indicates that GnRH antagonists fundamentally alter gonadotrope response mechanisms without inhibiting gonadotropin release. Beyond the ph...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Semen analyses were performed and serum and seminal plasma prolactin (PRL) concentrations were determined in 165 samples from 120 men seen with their wives because of infertility. The mean (+/- standard deviation) serum and seminal plasma PRL concentrations were 6.5 +/- 3.3 and 7.5 +/- 3.1 ng/ml, respectively. The mea...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59664-2
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To standardize and validate an assay for reactive oxygen species (ROS) in human semen. DESIGN:ROS levels assayed in blanks, negative and positive control samples (30% H2O2), and human semen, with the use of a luminol-based chemiluminescence assay measured in a single tube luminometer. SETTING:Andrology labo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.09.009
更新日期：2014-12-01 00:00:00
abstract：:A recently discovered syndrome is characterized by congenital immotility of the cilia. It consists of chronic infections in the respiratory system, male infertility, and, in about one-half of the cases, situs inversus. The syndrome thus includes Kartagener's syndrome. The syndrome provides a unique opportunity to gain...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43041-4
更新日期：1978-01-01 00:00:00
