The effects of feedback and contingent reinforcement on the exercise behavior of chronic pain patients.

abstract：:The molecular/genetic era has seen the discovery of a staggering number of molecules implicated in pain mechanisms [18,35,61,69,96,133,150,202,224]. This has stimulated pharmaceutical and biotechnology companies to invest billions of dollars to develop drugs that enhance or inhibit the function of many these molecules...

journal_title：Pain

authors： Reichling DB,Green PG,Levine JD

更新日期：2013-12-01 00:00:00

abstract：:Intense stress and fear have long been known to give rise to a suppression of pain termed "stress-induced analgesia", mediated by brainstem pain-modulating circuitry, including pain-inhibiting neurons of the rostral ventromedial medulla. However, stress does not invariably suppress pain, and indeed, may exacerbate it....

journal_title：Pain

authors： Martenson ME,Cetas JS,Heinricher MM

更新日期：2009-04-01 00:00:00

abstract：:In a study to determine how children describe the experience of pain, we queried a convenience sample of 100 children in hospitals and 114 children in church and private schools who were between 9 and 12 years old. The questions were designed to seek correlations by age among boys and girls, and between hospitalized a...

journal_title：Pain

authors： Savedra M,Gibbons P,Tesler M,Ward J,Wegner C

更新日期：1982-10-01 00:00:00

abstract：:Idiopathic chronic pain conditions with a mismatch between anatomical abnormalities and symptoms can be categorized as somatoform pain disorder according to the DSM-IV criteria. A dysfunction of pain processing circuits has been suggested as one underlying pathophysiological factor. There is accumulating evidence for ...

journal_title：Pain

authors： Gündel H,Valet M,Sorg C,Huber D,Zimmer C,Sprenger T,Tölle TR

更新日期：2008-07-15 00:00:00

abstract：:Monoclonal antibodies against GD(2) ganglioside, such as ch14.18, the human-mouse chimeric antibody, have been shown to be effective for the treatment of neuroblastoma. However, treatment is associated with generalized, relatively opiate-resistant pain. We investigated if a point mutation in ch14.18 antibody (hu14.18K...

journal_title：Pain

authors： Sorkin LS,Otto M,Baldwin WM 3rd,Vail E,Gillies SD,Handgretinger R,Barfield RC,Yu HM,Yu AL

更新日期：2010-04-01 00:00:00

abstract：:Thirty-eight patients maintained on opioid analgesics for non-malignant pain were retrospectively evaluated to determine the indications, course, safety and efficacy of this therapy. Oxycodone was used by 12 patients, methadone by 7, and levorphanol by 5; others were treated with propoxyphene, meperidine, codeine, pen...

journal_title：Pain

authors： Portenoy RK,Foley KM

更新日期：1986-05-01 00:00:00

abstract：:The efficacy of amitriptyline was evaluated in 28 patients with chronic oral-facial pain. Most of the patients had evidence of musculoskeletal pain while some had a history suggesting pain of neurogenic origin. Two patients had mixed elements of neurogenic and musculoskeletal pain. Amitriptyline was more effective tha...

journal_title：Pain

authors： Sharav Y,Singer E,Schmidt E,Dionne RA,Dubner R

更新日期：1987-11-01 00:00:00

abstract：:Investigating dose-dependent effects of placebo analgesia (PA) in laboratory subjects undergoing pain testing, we evaluated 2 hypotheses: (1) greater expectancy for relief produces greater PA, and (2) cued expectancy for relief triggered by a predictive cue leads to more enhanced analgesia than does passive expectancy...

journal_title：Pain

authors： Nakamura Y,Donaldson GW,Kuhn R,Bradshaw DH,Jacobson RC,Chapman RC

更新日期：2012-01-01 00:00:00

abstract：:Is a person's response to one noxious stimulus similar to his/her responses to other noxious stimuli? This long-investigated topic in pain research has provided inconclusive results. In the present study, 2 samples were studied: one using 60 healthy volunteers and the other using 29 patients with coronary artery disea...

journal_title：Pain

authors： Janal MN,Glusman M,Kuhl JP,Clark WC

更新日期：1994-09-01 00:00:00

abstract：:The aim of the present study has been to assess the responsiveness of various types of chronic pain to opioids given i.v. and tested against placebo in a double-blind, randomized fashion. Pain classified as primary nociceptive was effectively alleviated (P greater than 0.001) while neuropathic deafferentation pain was...

journal_title：Pain

authors： Arnér S,Meyerson BA

更新日期：1988-04-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) activity in the spinal cord plays a key role in sensitization to sensory stimuli during acute inflammation. In contrast, intrathecal administration of COX-2 specific inhibitors has minimal analgesic effects in an incisional model of postoperative pain. We investigated the role of COX isoforms ...

journal_title：Pain

authors： Zhu X,Conklin D,Eisenach JC

更新日期：2003-07-01 00:00:00

abstract：:Regular physical activity in healthy individuals prevents development of chronic musculoskeletal pain; however, the mechanisms underlying this exercise-induced analgesia are not well understood. Interleukin-10 (IL-10), an antiinflammatory cytokine that can reduce nociceptor sensitization, increases during regular phys...

journal_title：Pain

authors： Leung A,Gregory NS,Allen LH,Sluka KA

更新日期：2016-01-01 00:00:00

abstract：:Blockade of the noradrenergic input to the nucleus raphe magnus (NRM) by the injection of alpha-adrenergic antagonists produces hypoalgesia. Previous studies show that this hypoalgesia is blocked by the intrathecal injection of either phentolamine or methysergide. The present study demonstrates that depletion of spina...

journal_title：Pain

authors： Sagen J,Winker MA,Proudfit HK

更新日期：1983-07-01 00:00:00

abstract：:A study of the extent of sympathetic blockade after stellate ganglion block was assessed using liquid crystal thermography. Two volumes (10 and 20 ml) of bupivacaine 0.5% plain were used. Irrespective of the volume used cranial sympathetic block always occurred and thoracic sympathetic block never occurred. While uppe...

journal_title：Pain

authors： Hardy PAJ,Wells JCD

更新日期：1989-02-01 00:00:00

abstract：:The assessment and development of pain in children is reviewed in the first part of a two-part series. Assessment of pain in children has relied on self-report measures that have included visual analogue procedures using concrete stimuli for ratings. Behavioral assessment procedures are more sophisticated, but researc...

journal_title：Pain

authors： Lavigne JV,Schulein MJ,Hahn YS

更新日期：1986-11-01 00:00:00

abstract：:Self-hypnosis was taught to 5 highly hypnotisable patients referred to Auckland Hospital Pain Clinic. Evaluation included the Illness Self-Concept Repertory Grid (ISCRG) and follow-up was at 1 and 6 months post treatment. Consensus grids indicated the subjects initially identified with physical illness but this associ...

journal_title：Pain

authors： Large RG,James FR

更新日期：1988-11-01 00:00:00

abstract：:This laboratory-based study examined lagged associations between child pain behavior and maternal responses as a function of maternal catastrophizing (CAT). Mothers completed the parent version of the Pain Catastrophizing Scale. Children participated in a validated water ingestion procedure to induce abdominal discomf...

journal_title：Pain

authors： Langer SL,Romano J,Brown JD,Nielson H,Ou B,Rauch C,Zullo L,Levy RL

更新日期：2017-09-01 00:00:00

abstract：:Neuroimaging studies of patients with chronic pain have shown that neurotransmitter abnormalities, including increases in glutamate and decreases in GABA, could be responsible for the cortical hyperactivity and hyperalgesia/allodynia observed in some pain conditions. These finding are particularly evident in the insul...

journal_title：Pain

authors： Watson CJ

更新日期：2016-10-01 00:00:00

abstract：:We report a case control study comparing patients attending a pain clinic whose symptoms were not considered medically explained (cases) with those whose symptoms were considered medically explained (controls). Principal comparisons were psychiatric morbidity, medication use, and iatrogenic factors assessed by intervi...

journal_title：Pain

authors： Kouyanou K,Pither CE,Rabe-Hesketh S,Wessely S

更新日期：1998-06-01 00:00:00

abstract：:Epidural and intrathecal techniques are well established techniques in cancer pain. However, several questions remain unresolved. The several problems of long-term spinal opioid treatment in advance cancer patients were reviewed. Indications for the use of spinal opioids include patients treated by systemic opioids wi...

journal_title：Pain

authors： Mercadante S

更新日期：1999-01-01 00:00:00

abstract：:Neuropathic pain may be effectively relieved by electric stimulation of the spinal cord (SCS). However, the underlying mechanisms for the ensuing pain relief are poorly understood. In a rat model of neuropathy displaying hypersensitivity to innocuous tactile stimuli, (allodynia), we have earlier demonstrated that SCS ...

journal_title：Pain

authors： Cui JG,O'Connor WT,Ungerstedt U,Linderoth B,Meyerson BA

更新日期：1997-10-01 00:00:00

abstract：:The cell soma of primary afferent neurons in the dorsal root ganglion (DRG) is assigned by classical neurophysiology the role of a metabolic depot, charged with supporting the peripheral sensory ending, the conducting axon, and the central synaptic terminals. However, certain peculiarities of DRG morphology and physio...

journal_title：Pain

authors： Devor M

更新日期：1999-08-01 00:00:00

abstract：:In the skin surrounding a site of injury, hyperalgesia develops to mechanical stimuli. Two types of secondary hyperalgesia (to light touch and punctate stimuli) have recently been differentiated, based on different durations and sizes of the area involved. We studied secondary hyperalgesia in a subject who had a loss ...

journal_title：Pain

authors： Treede RD,Cole JD

更新日期：1993-05-01 00:00:00

abstract：:Recent research has focused on identification of clinically meaningful subgroupings within the chronic pain population in contrast to prior emphasis on the homogeneity of these patients. The present study investigates site of pain as a potentially useful classification variable for identification of differences among ...

journal_title：Pain

authors： Toomey TC,Gover VF,Jones BN

更新日期：1984-08-01 00:00:00

abstract：:Tailored treatment based on individual risk factors is an area with promise to improve options for pain relief. Musculoskeletal pain has a biopsychosocial nature, and multiple factors should be considered when determining risk for chronic pain. This study investigated whether subgroups comprised genetic and psychologi...

journal_title：Pain

authors： George SZ,Wallace MR,Wu SS,Moser MW,Wright TW,Farmer KW,Borsa PA,Parr JJ,Greenfield WH 3rd,Dai Y,Li H,Fillingim RB

更新日期：2015-01-01 00:00:00

abstract：:Primary neuronal cell bodies, whose peripheral axons comprised the cutaneous branch of the mylohyoid nerve or innervated the mandibular molar tooth pulp or the cornea, were labeled with HRP and their cross-sectional area was analyzed. Most of their cell bodies were smaller than 1000 microns2 in cross-sectional area an...

journal_title：Pain

authors： Sugimoto T,Takemura M,Wakisaka S

更新日期：1988-03-01 00:00:00

abstract：:The ability to sense and respond to thermal stimuli at varied environmental temperatures is essential for survival in seasonal areas. In this study, we show that mice respond similarly to ramping changes in temperature from a wide range of baseline temperatures. Further investigation suggests that this ability to adap...

journal_title：Pain

authors： Brenner DS,Golden JP,Vogt SK,Dhaka A,Story GM,Gereau RW IV

更新日期：2014-10-01 00:00:00

abstract：:A comparison between 102 depressed and 101 non-depressed pain patients, identified with the use of DSM-III criteria, showed that depressed patients were more often elderly and employed as compared to non-depressed patients who were significantly more often found to be younger (P less than 0.001) and were students (P l...

journal_title：Pain

authors： Chaturvedi SK

更新日期：1987-06-01 00:00:00

abstract：:Genetic influence on the sensory, motor and histopathological outcome of transient spinal cord ischemia was studied in Sprague-Dawley (SD), spontaneously hypertensive (SH) and Wistar-Kyoto (WKY) rats. Ischemia caused minor motor deficits and no identifiable morphological damage in the spinal cord of the majority of SD...

journal_title：Pain

authors： Wiesenfeld-Hallin Z,Hao JX,Xu XJ,Aldskogius H,Seiger Å

更新日期：1993-11-01 00:00:00

abstract：:Single units were recorded in dorsal roots or in the sciatic nerve of anaesthetised rats. It was shown by making sections, by stimulation and by collision that some ongoing nerve impulses were originating from the dorsal root ganglia and not from the central or peripheral ends of the axons. In a sample of 2731 intact ...

journal_title：Pain

authors： Wall PD,Devor M

更新日期：1983-12-01 00:00:00