Quality of life in 650 lung cancer survivors 6 months to 4 years after diagnosis.

Abstract:

OBJECTIVE:To present the results of a quality-of-life (QOL) assessment performed with the current version of the Lung Cancer Symptom Scale (LCSS) questionnaire in a large single-institutional data set of 650 patients with lung cancer. PATIENTS AND METHODS:The study group included 650 patients with pathologically confirmed primary lung cancer whose conditions were diagnosed and/or treated at the Mayo Clinic in Rochester, Minn, between January 1, 1997, and December 31, 2001. The QOL assessment was performed using the self-administered LCSS questionnaire (version 2) 6 months to 4 years after the diagnosis of lung cancer. RESULTS:The item response rate for all 9 LCSS questions was 94.2% with a minimum of 92.9%. Significant differences in overall QOL by sex (P=.04), Karnofsky scale (P<.001), weight loss (P<.001), disease stage (P<.001), and histology (P=.001) were found, but no significant differences in overall QOL by age (P=.17) or marital status (P=.06) were observed. CONCLUSION:Our data suggest that QOL in patients with lung cancer at varying times after diagnosis highly correlates with baseline prognostic factors (disease stage, histology, Karnofsky scale, weight loss, and sex).

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Svobodník A,Yang P,Novotny PJ,Bass E,Garces YI,Jett JR,Bonner JA,Sloan JA

doi

10.4065/79.8.1024

keywords:

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

1024-30

issue

8

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)62577-9

journal_volume

79

pub_type

杂志文章
  • Maintaining quality of life at the end of life.

    abstract::Despite the successful growth of the hospice movement during the past 30 years in the United States, almost 85% of Americans continue to die in hospitals or nursing homes. While the benefits of palliative care principles are well established, palliative care interventions remain underused in clinical practice in the s...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/75.12.1305

    authors: Rummans TA,Bostwick JM,Clark MM,Mayo Clinic Cancer Center Quality of Life Working Group.

    更新日期:2000-12-01 00:00:00

  • Elevated bone aluminum content in dialysis patients without osteomalacia.

    abstract::In almost all dialysis patients, bone aluminum content (BAC) is elevated in comparison with levels in normal subjects. Extremely high BAC (200 micrograms or more of aluminum per gram of bone) is significantly associated with classic aluminum-related osteomalacia. We noted three patients with elevated BAC but without h...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60539-4

    authors: McCarthy JT,Kurtz SB,McCall JT

    更新日期:1985-05-01 00:00:00

  • Mediastinal granuloma.

    abstract::In a group of 47 patients with mediastinal granulomas, the most common clinical symptoms were cough, chest pain, dysphagia, hemoptysis, and dyspnea. The main laboratory findings were right paratracheal or hilar mass on chest roentgenogram, positive histoplasmin skin test, and caseating granuloma on histopathologic exa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Strimlan CV,Dines DE,Payne WS

    更新日期:1975-12-01 00:00:00

  • Further study on the two-column plasma catecholamine assay.

    abstract::The two-column procedure for plasma catecholamine determination was adopted as a routine diagnostic test. It was found that the recovery of catecholamine added to properly preserved plasma was 65%. The most efficient recovery occurred when the water content of alumina used was above 23%. Both interassay and intra-assa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Jiang NS,Machacek D,Wadel OP

    更新日期:1976-02-01 00:00:00

  • Parathyroid hormone-related peptide in plasma of patients with hypercalcemia and malignant lesions.

    abstract::We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as radioligand, and prior extraction of the native peptide from plasma with C-2 cartridges. We determine...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62163-6

    authors: Kao PC,Klee GG,Taylor RL,Heath H 3rd

    更新日期:1990-11-01 00:00:00

  • An appraisal of endoscopic removal of malignant colonic polyps.

    abstract::The issue of whether patients who have invasive carcinoma in an otherwise benign polyp should undergo surgical resection of that bowel segment is controversial. We examined the records of 83 patients with such polyps that were removed endoscopically between 1978 and 1981. After exclusion of 18 patients from the study ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)65198-2

    authors: Fucini C,Wolff BG,Spencer RJ

    更新日期:1986-02-01 00:00:00

  • Effects of referral bias on surgical outcomes: a population-based study of surgical patients 90 years of age or older.

    abstract::During the 11-year period 1975 through 1985, 1,063 surgical procedures were performed on 795 Mayo Clinic patients 90 years of age or older. Preoperative conditions, surgical setting, and perioperative morbidity and mortality were analyzed in a comparison of the local residents of Olmsted County, Minnesota (N = 224), w...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62742-6

    authors: Warner MA,Hosking MP,Lobdell CM,Offord KP,Melton LJ 3rd

    更新日期:1990-09-01 00:00:00

  • Computerized bar code-based blood identification systems and near-miss transfusion episodes and transfusion errors.

    abstract:OBJECTIVE:To determine whether the use of a computerized bar code-based blood identification system resulted in a reduction in transfusion errors or near-miss transfusion episodes. PATIENTS AND METHODS:Our institution instituted a computerized bar code-based blood identification system in October 2006. After instituti...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2012.12.010

    authors: Nuttall GA,Abenstein JP,Stubbs JR,Santrach P,Ereth MH,Johnson PM,Douglas E,Oliver WC Jr

    更新日期:2013-04-01 00:00:00

  • Transient corticotropin deficiency in critical illness.

    abstract::We describe three critically ill patients who displayed indirect evidence of transient corticotropin deficiency. All these patients were elderly, were poorly nourished, and had unexplained hypotension intraoperatively or immediately postoperatively. During the hypotensive episodes, they had inappropriately low plasma ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60188-8

    authors: Kidess AI,Caplan RH,Reynertson RH,Wickus GG,Goodnough DE

    更新日期:1993-05-01 00:00:00

  • Validating the Diagnostic Accuracy of the Sleep Apnea Clinical Score for Use in Primary Care Populations.

    abstract:OBJECTIVE:To provide external validation of the diagnostic accuracy of the Sleep Apnea Clinical Score (SACS) tool in a new setting and patient population. PATIENTS AND METHODS:We conducted a prospective cohort study. Potential participants were adult family medicine patients. We excluded patients with a SACS of 0, kno...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2016.01.022

    authors: Grover M,Mookadam M,Chang YH,Parish J

    更新日期:2016-04-01 00:00:00

  • An integrated approach to evaluation of the solitary pulmonary nodule.

    abstract::In this article, we describe an integrated approach for detection and evaluation of solitary pulmonary nodules. Initial evaluation of the solitary pulmonary nodule includes tomography, fluoroscopy, and comparison with previously obtained roentgenograms. Subsequently, thin-section computed tomography and phantom densit...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)65012-5

    authors: Swensen SJ,Jett JR,Payne WS,Viggiano RW,Pairolero PC,Trastek VF

    更新日期:1990-02-01 00:00:00

  • Laparoscopic cholecystectomy: early Mayo Clinic experience.

    abstract::Prospective data and follow-up information were collected on the initial 200 patients who underwent laparoscopic cholecystectomy at the Mayo Clinic. The operation was completed laparoscopically in all but five patients, who required conversion to laparotomy because of dense scarring or stones in the common bile duct. ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60390-5

    authors: Donohue JH,Farnell MB,Grant CS,van Heerden JA,Wahlstrom HE,Sarr MG,Weaver AL,Ilstrup DM

    更新日期:1992-05-01 00:00:00

  • Apparent skepticism: capital punishment and medical evidence.

    abstract::In recent cases on the constitutionality of sentencing to death criminals who were younger than 18 years of age at the time of their crimes or who are mentally retarded, the US Supreme Court has rejected medical evidence that such persons categorically possess diminished culpability. Rather, the Court has accepted the...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60023-8

    authors: Helminski F

    更新日期:1993-01-01 00:00:00

  • Treatment options for breast cancer resistant to anthracycline and taxane.

    abstract::Breast cancer is the most common noncutaneous malignancy among every major ethnic group of women in the United States. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resist...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-6196(11)60585-5

    authors: Moreno-Aspitia A,Perez EA

    更新日期:2009-06-01 00:00:00

  • A contemporary conceptual model of hypochondriasis.

    abstract::Hypochondriasis (HC), which involves preoccupation with the fear of having a serious illness despite appropriate medical examination, is often encountered in medical settings. The most conspicuous feature of this disorder is seeking excessive reassurance from physicians, medical references, or self-inspection; however...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/77.12.1323

    authors: Abramowitz JS,Schwartz SA,Whiteside SP

    更新日期:2002-12-01 00:00:00

  • Impact of the SARS-CoV-2 Pandemic on Emergency Department Presentations in an Integrated Health System.

    abstract:OBJECTIVE:To quantify the impact of the severe acute respiratory syndrome coronavirus 2 pandemic on emergency department volumes and patient presentations and evaluate changes in community mortality for the purpose of characterizing new patterns of emergency care use. PATIENTS AND METHODS:This is an observational cros...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2020.09.019

    authors: Walker LE,Heaton HA,Monroe RJ,Reichard RR,Kendall M,Mullan AF,Goyal DG

    更新日期:2020-11-01 00:00:00

  • Paraneoplastic anti-neuronal nuclear IgG autoantibodies (type I) localize antigen in small cell lung carcinoma.

    abstract::Type I anti-neuronal nuclear autoantibodies (ANNA-I, also known as "Hu") are a distinctive serologic marker of small cell lung carcinoma (SCLC) in patients who have peripheral neuropathies or encephalomyeloradiculopathies. A tumor antigen reactive with these antibodies has been identified by other investigators by Wes...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62471-9

    authors: Kiers L,Altermatt HJ,Lennon VA

    更新日期:1991-12-01 00:00:00

  • Unusual recovery from acute panautonomic neuropathy after immunoglobulin therapy.

    abstract::A 33-year-old woman with acute idiopathic postganglionic panautonomic neuropathy experienced prompt recovery of all dysautonomic symptoms after receiving high-dose intravenous immunoglobulin therapy. Her recovery was complete within 6 months after onset of disease. This unusually rapid and complete recovery in compari...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/72.4.333

    authors: Smit AA,Vermeulen M,Koelman JH,Wieling W

    更新日期:1997-04-01 00:00:00

  • Binocular vertical diplopia.

    abstract::The assessment of a patient with binocular vertical diplopia begins with a thorough history and neuro-ophthalmologic examination. The neuro-ophthalmologic examination includes observation for a compensatory head, face, or chin position; ocular ductions and versions in the nine cardinal positions of gaze; the three-ste...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-6196(11)63620-3

    authors: Brazis PW,Lee AG

    更新日期:1998-01-01 00:00:00

  • Psychogenic urinary retention in women.

    abstract::There appears to be a spectrum of psychogenic urinary retention that is seen mostly in women. The degrees of psychiatric disorder and bladder disorder do not necessarily coincide. Some patients with psychogenic retention may have one acute episode temporally related to psychologic trauma. Others may present with probl...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Barrett DM

    更新日期:1976-06-01 00:00:00

  • Issues concerning androgen replacement therapy in postmenopausal women.

    abstract::A decrease in blood androgen levels is well documented in women who experience natural or surgical menopause. This change may be associated with various negative effects on bone metabolism in addition to psychosocial and sexuality aspects of life. A review of published information on androgen replacement therapy shows...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/72.11.1051

    authors: Abraham D,Carpenter PC

    更新日期:1997-11-01 00:00:00

  • Albuminocytologic Dissociation in Posterior Reversible Encephalopathy Syndrome.

    abstract:OBJECTIVES:To describe cerebrospinal fluid (CSF) findings in patients with posterior reversible encephalopathy syndrome (PRES) and to study its association with vasogenic edema. PATIENTS AND METHODS:Retrospective review of 73 consecutive prospectively collected adults diagnosed with PRES from January 1, 2000, through ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2015.07.018

    authors: Datar S,Singh TD,Fugate JE,Mandrekar J,Rabinstein AA,Hocker S

    更新日期:2015-10-01 00:00:00

  • Cardiorespiratory Fitness and the Risk of Serious Ventricular Arrhythmias: A Prospective Cohort Study.

    abstract::Cardiorespiratory fitness (CRF) is an established risk factor for cardiovascular disease outcomes. However, the relationship of CRF with risk of ventricular arrhythmias (VAs) is unknown. We aimed to assess the prospective association of CRF with the risk of serious VAs. Cardiorespiratory fitness, as measured by maxima...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2018.11.027

    authors: Laukkanen JA,Lavie CJ,Khan H,Kurl S,Kunutsor SK

    更新日期:2019-05-01 00:00:00

  • Separate Effects of Intensity and Amount of Exercise on Interindividual Cardiorespiratory Fitness Response.

    abstract:OBJECTIVE:To determine the separate effects of exercise intensity and amount on interindividual cardiorespiratory fitness (CRF) response. PARTICIPANTS AND METHODS:Participants were 121 (75 females, 62%) sedentary, middle-aged (mean [SD] age, 53.2 [7.5] years), abdominally obese adults who completed at least 90% of 5 w...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.mayocp.2015.07.024

    authors: Ross R,de Lannoy L,Stotz PJ

    更新日期:2015-11-01 00:00:00

  • Robotic Mitral Valve Repair: Indication for Surgery Does Not Influence Early Outcomes.

    abstract:OBJECTIVE:To evaluate the outcomes of robotic mitral valve repair (MVr) by primary indication per American Heart Association guidelines for surgery: class I vs class IIa. PATIENTS AND METHODS:From January 1, 2008, through September 30, 2016, 603 patients underwent robotic MVr for severe primary mitral regurgitation. M...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2019.05.025

    authors: Maltais S,Anwer LA,Daly RC,Poddi S,Topilsky Y,Enrique-Sarano M,Michelena HI,Mauermann WJ,Dearani JA

    更新日期:2019-11-01 00:00:00

  • Bronchoscopic phototherapy with hematoporphyrin derivative for treatment of localized bronchogenic carcinoma: a 5-year experience.

    abstract::Between December 1980 and April 1986 at our institution, 38 patients with cancer that involved the tracheobronchial tree (a total of 40 carcinomas) completed at least one course of hematoporphyrin derivative phototherapy. A complete response occurred in 13 patients (with 14 carcinomas). Eleven of these carcinomas did ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)61520-1

    authors: Edell ES,Cortese DA

    更新日期:1987-01-01 00:00:00

  • Making the Case to Study the Volume-Outcome Relationship in Hematologic Cancers.

    abstract::The positive relationship between the volume of health services (hospital and physician) and health-related outcomes is established in the complex surgical treatment of cancers and certain nononcologic medical conditions. However, this topic has not been systematically explored in the medical management of cancers. We...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2015.07.003

    authors: Go RS,Bottner WA,Gertz MA

    更新日期:2015-10-01 00:00:00

  • The metabolic syndrome: concepts and controversy.

    abstract::The metabolic syndrome is an insulin-resistant state characterized by a cluster of cardiovascular risk factors, including various combinations of abdominal obesity, glucose intolerance, hypertension, and atherogenic dyslipidemia (elevated triglyceride values, low high-density lipoprotein cholesterol levels, and small ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/81.12.1615

    authors: Johnson LW,Weinstock RS

    更新日期:2006-12-01 00:00:00

  • Decline in bilateral orchiectomy for prostate cancer in Olmsted county, Minnesota, 1956-2000.

    abstract:OBJECTIVE:To assess long-term secular trends in the utilization of bilateral compared with unilateral orchiectomy in the community. PATIENTS AND METHODS:This population-based descriptive study reviewed medical records of all Olmsted County, Minnesota, men undergoing orchiectomy between 1956 and 2000. RESULTS:Over the...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/76.12.1199

    authors: Melton LJ 3rd,Alothman KI,Achenbach SJ,O'Fallon WM,Zincke H

    更新日期:2001-12-01 00:00:00

  • Endorectal ultrasonographic staging of rectal carcinoma.

    abstract::Endorectal ultrasonography is a valuable imaging method for examination of the rectum and perirectal tissues. We assessed 50 patients with known rectal carcinoma prospectively by using a 7.0-MHz endorectal transducer to determine the depth of invasion of the rectal wall by tumor and the presence of lymphadenopathy. Tu...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62192-2

    authors: Jochem RJ,Reading CC,Dozois RR,Carpenter HA,Wolff BG,Charboneau JW

    更新日期:1990-12-01 00:00:00