Decline in bilateral orchiectomy for prostate cancer in Olmsted county, Minnesota, 1956-2000.

Abstract:

OBJECTIVE:To assess long-term secular trends in the utilization of bilateral compared with unilateral orchiectomy in the community. PATIENTS AND METHODS:This population-based descriptive study reviewed medical records of all Olmsted County, Minnesota, men undergoing orchiectomy between 1956 and 2000. RESULTS:Over the 45-year study period, 381 Olmsted County men had a first unilateral orchiectomy, while 431 underwent bilateral orchiectomy (including 8 with a second unilateral orchiectomy). There was no change over time in the age-adjusted utilization of unilateral orchiectomy, which was performed for a wide range of indications, mostly cryptorchidism and testicular malignancy. Most bilateral procedures, on the other hand, were in elderly men for castration, and trends over time generally paralleled those reported for prostate cancer in this community. CONCLUSION:The declining incidence of prostate cancer in recent years, combined with a shift to earlier stages and younger ages at diagnosis, and the development of pharmacological approaches to hormonal manipulation have led to a dramatic decline in the utilization of bilateral orchiectomy, while unilateral orchiectomy rates have remained unchanged.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Melton LJ 3rd,Alothman KI,Achenbach SJ,O'Fallon WM,Zincke H

doi

10.4065/76.12.1199

keywords:

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

1199-203

issue

12

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)62795-X

journal_volume

76

pub_type

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