Possible involvement of p44/p42 MAP kinase in retinoic acid-stimulated vascular endothelial growth factor release in aortic smooth muscle cells.

abstract：:Evidence for chemical and biological heterogeneity of human plasma lipoprotein density classes has been steadily accumulating over the last 15 years. Furthermore, several recent reports have indicated potential clinical significance of certain lipoprotein subspecies as either atherogenic or antiatherogenic. It is gene...

journal_title：Atherosclerosis

authors： Koren E,Armstrong VW,Mueller G,Wilson PR,Schuff-Werner P,Thiery J,Eisenhauer T,Alaupovic P,Seidel D

更新日期：1992-08-01 00:00:00

abstract：:Five homozygous patients with familial hypercholesterolemia (FH) are described. Their serum cholesterol levels were between 603 and 907 mg/dl, with an average of 714 mg/dl. The mean value of serum cholesterol levels of the obligate heterozygous parents was 270 mg/dl. In the patient group, 87% of the serum cholesterol ...

journal_title：Atherosclerosis

authors： Cai HJ,Fan LM,Huang MG,Chen XY,Liu GQ,Chen Q

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Increased activity of matrix metalloproteinase (MMP)-2 is observed in aortas of different models of hypertension, and its activation is directly mediated by oxidative stress. As quercetin is an important flavonoid with significant antioxidant effects, the hypothesis here is that quercetin will reduc...

journal_title：Atherosclerosis

authors： Pereira SC,Parente JM,Belo VA,Mendes AS,Gonzaga NA,do Vale GT,Ceron CS,Tanus-Santos JE,Tirapelli CR,Castro MM

更新日期：2018-03-01 00:00:00

abstract：:Research has indicated that inflammation promote all phases of atherosclerosis. The current study tested the hypothesis that rhinosinusitis is a risk marker for myocardial infarction (MI). Data on the general population were obtained from the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005). The study coh...

journal_title：Atherosclerosis

authors： Hao WR,Lin HW,Chao PZ,Wu CW,Yen TH,Liu JC,Liou TH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The sex- and age-related differences in the composition of iliofemoral atherosclerotic plaques are largely unknown. Therefore, the aim of the current study is to gain insight into plaque composition across strata of age and sex in a large cohort of vascular surgery patients. METHODS:Peripheral athe...

journal_title：Atherosclerosis

authors： de Bakker M,Timmerman N,van Koeverden ID,de Kleijn DPV,de Borst GJ,Pasterkamp G,Boersma E,den Ruijter HM

更新日期：2020-10-01 00:00:00

abstract：:The ontogenic development of lipoprotein lipase and liver triglyceride hydrolase was studied in the rat. The enzyme activity measured in extrahepatic tissues fulfilled the criteria of lipoprotein lipase from the onset of measurable activity, i.e. it was inhibited by protamine and 1 M NaCl and showed requirement for se...

journal_title：Atherosclerosis

authors： Chajek T,Stein O,Stein Y

更新日期：1977-04-01 00:00:00

abstract：:Extensive research has been carried out in recent years to discover the potential risk factors contributing to cardiac allograft atherogenesis. Injury to endothelial cells has been regarded as an important early mechanism in the development of transplant atherosclerosis; it leads to the manifestation of epicardial and...

journal_title：Atherosclerosis

authors： Liu Z,Wildhirt SM,Weismüller S,Schulze C,Conrad N,Reichart B

更新日期：1998-09-01 00:00:00

abstract：:This review evaluates novel beneficial effects of circulating endothelial progenitor cells (EPCs) as shown by several preclinical studies and clinical trials carried out to test the safety and feasibility of using EPCs. There are 31 registered clinical trials (and many others still ongoing) and 19 published studies. E...

journal_title：Atherosclerosis

authors： Napoli C,Hayashi T,Cacciatore F,Casamassimi A,Casini C,Al-Omran M,Ignarro LJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:P-selectin is a cellular adhesion molecule that has been shown to be crucial in development of coronary heart disease (CHD). We sought to determine the role of P-selectin on the risk of atherosclerosis in a large multi-ethnic population. METHODS:Data from the Multi-Ethnic Study of Atherosclerosis (MESA), inc...

journal_title：Atherosclerosis

authors： Bielinski SJ,Berardi C,Decker PA,Kirsch PS,Larson NB,Pankow JS,Sale M,de Andrade M,Sicotte H,Tang W,Hanson NQ,Wassel CL,Polak JF,Tsai MY

更新日期：2015-05-01 00:00:00

abstract：:The lifetime cardiovascular risk of a diabetic patient is approximately 4-5 times higher than that of an age and sex matched individual without diabetes mellitus. Despite the well-publicized cardiovascular risk equivalence of diabetes mellitus, it has become apparent that not all diabetic patients are equally at high-...

journal_title：Atherosclerosis

authors： Raggi P

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Adherence to a Mediterranean-style diet (MeDi) may protect against clinical vascular events by reducing atherosclerosis, but data is limited. This is the first observational study of the association between MeDi adherence and carotid plaque thickness and area. METHODS:The study included 1374 participants of ...

journal_title：Atherosclerosis

authors： Gardener H,Wright CB,Cabral D,Scarmeas N,Gu Y,Cheung K,Elkind MS,Sacco RL,Rundek T

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. METHODS:C-terminal pla...

journal_title：Atherosclerosis

authors： Jovanovich A,Ix JH,Gottdiener J,McFann K,Katz R,Kestenbaum B,de Boer IH,Sarnak M,Shlipak MG,Mukamal KJ,Siscovick D,Chonchol M

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction. METHODS AND RESULTS:Coronary endothelial function was assessed in 490 patients between November 1993 and February 2...

journal_title：Atherosclerosis

authors： Ford MA,McConnell JP,Lavi S,Rihal CS,Prasad A,Sandhu GS,Hartman SJ,Lerman LO,Lerman A

更新日期：2009-11-01 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) and atherosclerosis are common causes of mortality and morbidity in an aging population. Angiogenesis is believed to contribute to the development and progression of these diseases. Angiopoietins (angpts) are known to be important regulators of angiogenesis. Angpts can also influence in...

journal_title：Atherosclerosis

authors： Trollope AF,Golledge J

更新日期：2011-02-01 00:00:00

abstract：:We looked for antibodies against endothelial cells, monocytes, fibroblasts, lymphocytes and Epstein-Barr virus transformed lymphocytes in the sera of 28 elderly and 18 middle-aged patients with atherosclerotic peripheral arterial disease and 13 controls. Inclusion criteria were symptomatic peripheral arterial disease ...

journal_title：Atherosclerosis

authors： D'Anastasio C,Impallomeni M,McPherson GA,Clements WG,Howells GL,Brooks PA,Batchelor JR

更新日期：1988-11-01 00:00:00

abstract：:83 pairs of twins, aged 50-74 years, were studied with respect to their serum apoproteins (A-I, A-II, B, C-II, C-III and E) and cholesterol concentrations. Each of the variables showed a higher intraclass correlation in the MZ twins than in the DZ twins. HDL cholesterol showed the highest intraclass correlation among ...

journal_title：Atherosclerosis

authors： Hayakawa K,Shimizu T,Ohba Y,Tomioka S

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:To examine the associations of maternal smoking in pregnancy with development of cholesterol levels from childhood to adulthood. METHODS:Total cholesterol, high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol were measured annually from 1975 to 1993 and in 2002 in 350 subj...

journal_title：Atherosclerosis

authors： Jaddoe VWV,de Ridder MAJ,van den Elzen APM,Hofman A,Uiterwaal CSPM,Witteman JCM

更新日期：2008-01-01 00:00:00

abstract：:The insertion/deletion (I/D) polymorphism of the ACE gene may be involved in structural arterial changes. Aim of the present study was to assess the relationship between the ACE I/D gene and vessel wall stiffness among older adults. The study was conducted within the Rotterdam study, a population-based cohort study in...

journal_title：Atherosclerosis

authors： Mattace-Raso FU,van der Cammen TJ,Sayed-Tabatabaei FA,van Popele NM,Asmar R,Schalekamp MA,Hofman A,van Duijn CM,Witteman JC

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:The aim of this systematic review was to perform a meta-analysis of randomized controlled trials (RCTs) examining the efficacy of fibrate therapy in reducing plasma concentration or activity of plasminogen activator inhibitor 1 (PAI-1). METHODS:Scopus and MEDLINE databases were searched (up to October 15, 20...

journal_title：Atherosclerosis

authors： Sahebkar A,Simental-Mendía LE,Watts GF,Golledge J

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:P2X(7) receptor (P2X(7)R), upon its stimulation with extracellular ATP, modulates several inflammatory responses in different cell types. No information is available on its presence in human adipocytes and its potential involvement in the chronic inflammation associated with metabolic syndrome (MS). Therefore...

journal_title：Atherosclerosis

authors： Madec S,Rossi C,Chiarugi M,Santini E,Salvati A,Ferrannini E,Solini A

更新日期：2011-12-01 00:00:00

abstract：:Long-term effects of pravastatin and probucol on serum cholesteryl ester transfer protein (CETP) and xanthoma/xanthelasma size were compared. Twenty-three patients with primary hypercholesterolemia and xanthoma/xanthelasma, including 11 patients with heterozygous familial hypercholesterolemia, were treated with pravas...

journal_title：Atherosclerosis

authors： Inazu A,Koizumi J,Kajinami K,Kiyohar T,Chichibu K,Mabuchi H

更新日期：1999-08-01 00:00:00

abstract：:The response to therapy with hypolipidemic agents shows considerable individual variation. These differences may be due to the interaction of environmental and genetic factors that affect drug bioavailability, receptor function or ligand structure. Our objective was to assess the effect of apolipoprotein (apo) E genot...

journal_title：Atherosclerosis

authors： Pedro-Botet J,Schaefer EJ,Bakker-Arkema RG,Black DM,Stein EM,Corella D,Ordovas JM

更新日期：2001-09-01 00:00:00

abstract：:The aim of this study was to determine whether an abnormality in low density lipoprotein (LDL) metabolism could be demonstrated in fibroblasts cultured from normolipidaemic subjects with atherosclerosis. Seventeen male subjects aged 30-55 years with normal plasma lipid concentrations were divided into 2 groups on the ...

journal_title：Atherosclerosis

authors： Behrman RG,Wynn V

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:α-Linolenic acid (ALA), the vegetable n-3 fatty acid, appears to have antiatherosclerotic properties akin to those of marine n-3 fatty acids. A prior study in a US population with low fish intake showed an inverse association between ALA intake and carotid plaque. We examined the association between the ALA s...

journal_title：Atherosclerosis

authors： Sala-Vila A,Cofán M,Núñez I,Gilabert R,Junyent M,Ros E

更新日期：2011-01-01 00:00:00

abstract：:The effect of low dose (600 mg/day) alpha-tocopheryl nicotinate on serum lipoprotein(a) (Lp(a] concentration was studied in 28 hyperlipidaemic patients. Serum lipids, lipoproteins and apolipoproteins, except for Lp(a), tended to increase after treatment. In particular, the changes in HDL-cholesterol and apo C-II level...

journal_title：Atherosclerosis

authors： Noma A,Maeda S,Okuno M,Abe A,Muto Y

更新日期：1990-10-01 00:00:00

abstract：:Hepatic lipase (HL) not only plays an important role in plasma lipoprotein transport, but may also affect intracellular lipid metabolism. We hypothesize that HL expression is regulated as an integral part of intracellular lipid homeostasis. Addition of oleate (1 mM) to HepG2 cells increased HL secretion to 134+/-14% o...

journal_title：Atherosclerosis

authors： Botma GJ,van Deursen D,Vieira D,van Hoek M,Jansen H,Verhoeven AJ

更新日期：2005-03-01 00:00:00

abstract：:Patients with homozygous familial hypercholesterolemia (FH), as a result of the increased levels and prolonged residence time of low density lipoprotein (LDL) in plasma, have a strong tendency toward accumulation of LDL-cholesterol in the arterial wall, causing premature atherosclerosis. This phenomenon may enhance pe...

journal_title：Atherosclerosis

authors： Napoli C,Postiglione A,Triggiani M,Corso G,Palumbo G,Carbone V,Ruocco A,Ambrosio G,Montefusco S,Malorni A,Condorelli M,Chiariello M

更新日期：1995-12-01 00:00:00

abstract：:The insulin response to a standard oral glucose tolerance test (OGTT) and other anthropometric and biochemical risk factors for coronary heart disease (CHD) were measured in a random sample of 107 Edinburgh men, who were initially studied in 1976 when they were 40 and who were reexamined in 1988-89. Fasting glucose an...

journal_title：Atherosclerosis

authors： Hargreaves AD,Logan RL,Elton RA,Buchanan KD,Oliver MF,Riemersma RA

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The CHA(2)DS(2)-VASc (congestive heart failure, hypertension, age ≥ 75 years (doubled), type 2 diabetes, previous stroke, transient ischemic attack, or thromboembolism (doubled), vascular disease, age 65-75 years, and sex category) score was published as a predictive scoring model for stroke in atrial fibril...

journal_title：Atherosclerosis

authors： Gary T,Belaj K,Hafner F,Hackl G,Froehlich H,Pilger E,Brodmann M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Treatment of severe peripheral arterial occlusive disease requires percutaneous revascularization. However, little is known about risk factors or predictors for reocclusion/restenosis. Cysteinyl leukotrienes are highly bioactive lipid mediators of inflammation. Their intravascular production may tak...

journal_title：Atherosclerosis

authors： Maga P,Sanak M,Rewerska B,Maga M,Jawien J,Wachsmann A,Rewerski P,Szczeklik W,Celejewska-Wójcik N

更新日期：2016-06-01 00:00:00