Characterization of surface-immobilized layers of intact liposomes.

abstract：:Although research on nanopaper structures from cellulose nanofibrils (CNFs) is well established, the mechanical behavior is not well understood, especially not when CNF is combined with hard nanoparticles. Cationic CNF (Q-CNF) was prepared and successfully decorated by anionic nanodiamond (ND) nanoparticles in hydroco...

journal_title：Biomacromolecules

authors： Morimune-Moriya S,Salajkova M,Zhou Q,Nishino T,Berglund LA

更新日期：2018-07-09 00:00:00

abstract：:Nature shows excellent control over the mechanics of fibrous hydrogels by assembling protein fibers into bundles of well-defined dimensions. Yet, obtaining artificial materials displaying controlled bundling remains a challenge. Here, we developed genetically engineered protein-based polymers functionalized with hepar...

journal_title：Biomacromolecules

authors： Włodarczyk-Biegun MK,Slingerland CJ,Werten MW,van Hees IA,de Wolf FA,de Vries R,Stuart MA,Kamperman M

更新日期：2016-06-13 00:00:00

abstract：:In this work, biodegradable branched polycationic polymers were synthesized by Michael addition polymerization from different amine monomers and the triacrylate monomer trimethylolpropane triacrylate. The polymers varied in the number of amines that dissociate in different pH ranges, which are considered to be benefic...

journal_title：Biomacromolecules

authors： Chew SA,Hacker MC,Saraf A,Raphael RM,Kasper FK,Mikos AG

更新日期：2010-03-08 00:00:00

abstract：:We studied methoxy poly(ethylene glycol)-b-poly(ε-caprolactone)-b-poly(2-dimethylaminoethyl methacrylate) (mPEG-b-PCL-b-PDMAEMA) nanoparticles as the codelivery vector of hydrophobic drug and pDNA by employing dynamic light scattering (DLS), ζ potential, transmission electron microscopy (TEM), gel retardation assay, a...

journal_title：Biomacromolecules

authors： Yue X,Qiao Y,Qiao N,Guo S,Xing J,Deng L,Xu J,Dong A

更新日期：2010-09-13 00:00:00

abstract：:The mechanical rigidity and degradation rate of hydrogels utilized as cell transplantation vehicles have been regarded as critical factors in new tissue formation. However, conventional approaches to accelerate the degradation rate of gels deteriorate their function as a mechanical support in parallel. We hypothesized...

journal_title：Biomacromolecules

authors： Kong HJ,Kaigler D,Kim K,Mooney DJ

更新日期：2004-09-01 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:Partially benzylamidated, amphipathic poly(gamma-glutamic acid) (BzPGA) was synthesized from poly(gamma-glutamic acid) (PGA) and benzylamine by direct amidation in dimethyl sulfoxide (DMSO). Benzylamine and PGA were heated in DMSO for 1 to 26 h at temperatures between 110 and 130 degrees C, producing derivatives of va...

journal_title：Biomacromolecules

authors： Novak L,Banyai I,Fleischer-Radu JE,Borbély J

更新日期：2007-05-01 00:00:00

abstract：:The introduction of polymers into a chiral nematic cellulose nanocrystal (CNC) matrix allows for the tuning of optical and mechanical properties, enabling the development of responsive photonic materials. In this study, we explored the incorporation of hydroxypropyl cellulose (HPC) into a CNC film prepared by slow eva...

journal_title：Biomacromolecules

authors： Walters CM,Boott CE,Nguyen TD,Hamad WY,MacLachlan MJ

更新日期：2020-03-09 00:00:00

abstract：:Chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester, and poly(ethylene glycol) groups were prepared successfully using dendrimer acetal by reductive N-alkylation. The synthetic procedure could be accomplished by one-step reaction without organic solvent. The degree of substitution of de...

journal_title：Biomacromolecules

authors： Sashiwa H,Yajima H,Aiba S

更新日期：2003-09-01 00:00:00

abstract：:The main objective of the present work was the development of new nanoparticulate carrier systems for the delivery of plasmid DNA. These new carriers consist of a blend matrix formed by a poly(lactic-co-glycolic acid) (PLGA) copolymer and polyoxyethylene derivatives. More specifically, we have prepared nanostructures ...

journal_title：Biomacromolecules

authors： Csaba N,Caamaño P,Sánchez A,Domínguez F,Alonso MJ

更新日期：2005-01-01 00:00:00

abstract：:The thermally induced aggregation of bovine β-lactoglobulin in the glass state was studied both as the pure protein and in trehalose mixtures. Calorimetric measurements and size exclusion chromatography were used to characterize the glass state and aggregation, respectively. The initial aggregation rate was characteri...

journal_title：Biomacromolecules

authors： Pérez-Moral N,Adnet C,Noel TR,Parker R

更新日期：2010-11-08 00:00:00

abstract：:Single-molecule total internal reflection fluorescence microscopy was used to observe the dynamic behavior of polycytosine single-stranded DNA (ssDNA) (1-50 nucleotides long) at the interface between aqueous solution and hydrophilic (oligoethylene glycol-modified fused silica, OEG) and hydrophobic (octadecyltriethoxys...

journal_title：Biomacromolecules

authors： Monserud JH,Schwartz DK

更新日期：2012-12-10 00:00:00

abstract：:A one-pot synthetic methodology for fabricating stimuli-responsive hemicellulose-based hydrogels was developed that consists of the in situ formation of magnetic iron oxide (Fe3O4) nanoparticles during the covalent cross-linking of O-acetyl-galactoglucomannan (AcGGM). The Fe3O4 nanoparticle content controlled the ther...

journal_title：Biomacromolecules

authors： Zhao W,Odelius K,Edlund U,Zhao C,Albertsson AC

更新日期：2015-08-10 00:00:00

abstract：:The encapsulation of live cells with polymeric coat-ings is a versatile approach to modulate or control the response cells to their environment. The layer-by-layer (LbL) self-assembly of nonimmunogenic polyelectrolytes is employed here to attenuate or suppress the binding of antibodies to live red blood cells (RBCs) a...

journal_title：Biomacromolecules

authors： Mansouri S,Merhi Y,Winnik FM,Tabrizian M

更新日期：2011-03-14 00:00:00

abstract：:The synthesis, characterization, and degradation kinetics of three alpha-cyclodextrin (alpha-CD)-poly(ethylene glycol) (PEG) polyrotaxanes with endcaps that were installed using Cu(I)-catalyzed Huisgen cyclization is reported. PEG1500, azidated with azidoacetic acid, was threaded with alpha-CD to form a pseudopolyrota...

journal_title：Biomacromolecules

authors： Loethen S,Ooya T,Choi HS,Yui N,Thompson DH

更新日期：2006-09-01 00:00:00

abstract：:Low tolerability and tumor selectivity restricts many potent anticancer drugs including mertansine from wide clinical use. Here, glutathione-activatable hyaluronic acid-SS-mertansine prodrug (HA-SS-DM1) was designed and developed to achieve enhanced tolerability and targeted therapy of CD44+ human breast tumor xenogra...

journal_title：Biomacromolecules

authors： Zhong P,Zhang J,Deng C,Cheng R,Meng F,Zhong Z

更新日期：2016-11-14 00:00:00

abstract：:A unified kinetic pathway for the enzyme-catalyzed polymerization and degradation of poly(ε-caprolactone) was developed. This model tracks the complete distribution of individual chain lengths, both enzyme-bound and in solution, and successfully predicts monomer conversion and the molecular mass distribution as a func...

journal_title：Biomacromolecules

authors： Johnson PM,Kundu S,Beers KL

更新日期：2011-09-12 00:00:00

abstract：:Dragline silk from orb-weaving spiders is a copolymer of two large proteins, major ampullate spidroin 1 (MaSp1) and 2 (MaSp2). The ratio of these proteins is known to have a large variation across different species of orb-weaving spiders. NMR results from gland material of two different species of spiders, N. clavipe...

journal_title：Biomacromolecules

authors： An B,Jenkins JE,Sampath S,Holland GP,Hinman M,Yarger JL,Lewis R

更新日期：2012-12-10 00:00:00

abstract：:Polycations often suffer from the irreconcilable inconsistency between transfection efficiency and toxicity. Polymers with high molecular weight (MW) and cationic charge feature potent gene delivery capabilities, while in the meantime suffer from strong chemotoxicity, restricted intracellular DNA release, and low stab...

journal_title：Biomacromolecules

authors： He H,Bai Y,Wang J,Deng Q,Zhu L,Meng F,Zhong Z,Yin L

更新日期：2015-04-13 00:00:00

abstract：:Electrospun natural polymer membranes were fabricated from collagen or gelatin coated with a bioactive recombinant fragment of perlecan, a natural heparan sulfate proteoglycan. The electrospinning process allowed the facile processing of a three-dimensional, porous fibril (2-6 microm in diameter) matrix suitable for t...

journal_title：Biomacromolecules

authors： Casper CL,Yang W,Farach-Carson MC,Rabolt JF

更新日期：2007-04-01 00:00:00

abstract：:As an aim toward developing biologically mimetic and functional nanofiber-based tissue engineering scaffolds, we demonstrated the encapsulation of a model protein, fluorescein isothiocyanate-conjugated bovine serum albumin (fitcBSA), along with a water-soluble polymer, poly(ethylene glycol) (PEG), within the biodegrad...

journal_title：Biomacromolecules

authors： Zhang YZ,Wang X,Feng Y,Li J,Lim CT,Ramakrishna S

更新日期：2006-04-01 00:00:00

abstract：:Polyrotaxanes, a family of rod-shaped nanomaterials comprised of noncovalent polymer/macrocycle assemblies, are being used in a growing number of materials and biomedical applications. Their physiochemical properties can vary widely as a function of composition, potentially leading to different in vivo performance out...

journal_title：Biomacromolecules

authors： Collins CJ,Mondjinou Y,Loren B,Torregrosa-Allen S,Simmons CJ,Elzey BD,Ayat N,Lu ZR,Thompson D

更新日期：2016-09-12 00:00:00

abstract：:alpha-Conotoxins possess a conserved four-cysteine framework and disulfide linkages (C(1)(-)(3), C(2)(-)(4)) that fold toward the globular conformation with absolute fidelity. Despite the presence of a similar conserved set of cysteine framework, chi/lambda-conotoxins adopt an alternate disulfide-pairing (C(1)(-)(4), ...

journal_title：Biomacromolecules

authors： Kang TS,Jois SD,Kini RM

更新日期：2006-08-01 00:00:00

abstract：:The carboxyl-terminal domain (CTD, residues 146-231) of the HIV-1 capsid (CA) protein plays an important role in the CA-CA dimerization and viral assembly of the human immunodeficiency virus type 1. Disrupting the native conformation of the CA is essential for blocking viral capsid formation and viral replication. Thu...

journal_title：Biomacromolecules

authors： Yu X,Wang Q,Yang JC,Buch I,Tsai CJ,Ma B,Cheng SZ,Nussinov R,Zheng J

更新日期：2009-02-09 00:00:00

abstract：:Hydrogel fibers that possessed a cell-adhesive surface and were degradable via enzymatic reactions were developed for fabricating tubular constructs with smooth muscle cell (SMC) and endothelial cell (EC) layers, similar to native blood vessels, in collagen gels. The fibers were prepared by soaking hydrogel fibers pre...

journal_title：Biomacromolecules

authors： Sakai S,Yamaguchi S,Takei T,Kawakami K

更新日期：2008-07-01 00:00:00

abstract：:The purpose of this study is to investigate the combined effects of oxygen plasma treatments and silver nanoparticles (Ag) on PLGA in order to modulate the surface antimicrobial properties through tunable bacteria adhesion mechanisms. PLGA nanocomposite films, produced by solvent casting with 1 wt % and 7 wt % of Ag n...

journal_title：Biomacromolecules

authors： Fortunati E,Mattioli S,Visai L,Imbriani M,Fierro JL,Kenny JM,Armentano I

更新日期：2013-03-11 00:00:00

abstract：:Fluorescence-tagged coniferyl alcohols, coniferyl alcohol γ-coupled by ethylenediamine spacers to dimethylaminocoumarin or nitrobenzofuran fluorophores, were tested as photoprobes to study the oxidase-mediated polymerization of monolignols. The fluorescent coniferyl alcohol derivatives readily underwent peroxidase-cat...

journal_title：Biomacromolecules

authors： Tobimatsu Y,Davidson CL,Grabber JH,Ralph J

更新日期：2011-05-09 00:00:00

abstract：:Nanofibrous materials containing the antitumor drug doxorubicin hydrochloride (DOX) were easily prepared using a one-step method by electrospinning of DOX/poly(L-lactide-co-D,L-lactide) (coPLA) and DOX/quaternized chitosan (QCh)/coPLA solutions. The pristine and DOX-containing mats were characterized by ATR-FTIR and X...

journal_title：Biomacromolecules

authors： Ignatova MG,Manolova NE,Toshkova RA,Rashkov IB,Gardeva EG,Yossifova LS,Alexandrov MT

更新日期：2010-06-14 00:00:00

abstract：:This paper describes the synthesis and characterization of a novel organic polymer coating for the prevention of the growth of Pseudomonas aeruginosa on the solid surface of three-dimensional objects. Substrata were encapsulated with polyterpenol thin films prepared from terpinen-4-ol using radio frequency plasma enha...

journal_title：Biomacromolecules

authors： Bazaka K,Jacob MV,Truong VK,Wang F,Pushpamali WA,Wang JY,Ellis AV,Berndt CC,Crawford RJ,Ivanova EP

更新日期：2010-08-09 00:00:00

abstract：:A three-dimensional structure consisting of poly(ε-caprolactone) (PCL) nanofibers covered by periodically spaced PCL crystal lamellae, a self-induced nanohybrid shish-kebab (SINSK) structure, was created using electrospinning followed by a self-induced crystallization. The resulting structure that resembles the nanoto...

journal_title：Biomacromolecules

authors： Wang X,Salick MR,Wang X,Cordie T,Han W,Peng Y,Li Q,Turng LS

更新日期：2013-10-14 00:00:00