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Back to central tolerance.

Abstract：

:The establishment and maintenance of immunological tolerance entails both central and peripheral mechanisms. The latter have been highlighted in the past several years, mostly because of great interest in the activities of regulatory T cells. However, an important role for central tolerance mechanisms has been reemphasized by recent results on human autoimmune diseases, including APECED and type 1 diabetes.

journal_name

Immunity

journal_title

Immunity

authors

Mathis D,Benoist C

doi

10.1016/s1074-7613(04)00111-6

keywords:

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

509-16

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(04)00111-6

journal_volume

20

pub_type

杂志文章,评审

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