Abstract:
:Protein tyrosine phosphorylation (PY) is a well-known signalling mechanism which is also involved in host-parasite interactions. Despite its transcendence, PY has been poorly studied in parasitic helminths. The aim of this study is to examine the effect of bile salts on the PY pattern in parasitic trematodes. Two distinct adult models were analysed: Echinostoma friedi, of intestinal habitat, and Fasciola hepatica, naturally inhabitant of host biliary channels. Our results show that bile salts induce specific and distinct protein PY in both trematode species, indicating that this signalling process seems to be also involved in host-trematode relationships.
journal_name
Exp Parasitoljournal_title
Experimental parasitologyauthors
Marcilla A,Rubia JE,Espert A,Carpena I,Esteban JG,Toledo Rdoi
10.1016/j.exppara.2004.01.006keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
56-8issue
1-2eissn
0014-4894issn
1090-2449pii
S0014489404000153journal_volume
106pub_type
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