An AFLP-based genetic linkage map of channel catfish (Ictalurus punctatus) constructed by using an interspecific hybrid resource family.

abstract：:We describe allelic variation at 28 gene loci in natural populations of D. willistoni. Seventy samples were studied from localities extending from Mexico and Florida, through Central America, the West Indies, and tropical South America, down to South Brazil. At least several hundred, and often several thousand, genome...

journal_title：Genetics

authors： Ayala FJ,Powell JR,Tracey ML,Mourão CA,Pérez-Salas S

更新日期：1972-01-01 00:00:00

abstract：:We demonstrate the involvement of suppressor of meiotic silencing-2 (sms-2(+)), a Neurospora gene coding for an Argonaute-like protein, in meiotic silencing and normal sexual development. ...

journal_title：Genetics

authors： Lee DW,Pratt RJ,McLaughlin M,Aramayo R

更新日期：2003-06-01 00:00:00

abstract：:Whereas nonlinear relationships between genes are acknowledged, there exist only a few methods for estimating nonlinear gene coexpression networks or gene regulatory networks (GCNs/GRNs) with common deficiencies. These methods often consider only pairwise associations between genes, and are, therefore, poorly capable ...

journal_title：Genetics

authors： Kontio JAJ,Rinta-Aho MJ,Sillanpää MJ

更新日期：2020-07-01 00:00:00

abstract：:Diversity in insect pigmentation, encompassing a wide range of colors and spatial patterns, is among the most noticeable features distinguishing species, individuals, and body regions within individuals. In holometabolous species, a significant portion of such diversity can be attributed to the melanin synthesis genes...

journal_title：Genetics

authors： Liu J,Lemonds TR,Marden JH,Popadić A

更新日期：2016-05-01 00:00:00

abstract：:In random mating autopolyploid populations which have not reached equilibrium, two alleles may be interdependent as a result of the phenomenon of gametic recombination, i.e. the maintenance through successive gamete generations of an association of two alleles from the same gamete in a source reference generation. Any...

journal_title：Genetics

authors： Gallais A

更新日期：1974-03-01 00:00:00

abstract：:We derive a formula for the distribution of the length T of the recombination interval containing a target gene and using N gametes in a region where R kilobases correspond to 1 cM. The formula can be used to calculate the number of meiotic events required to narrow a target gene down to a specific interval size and h...

journal_title：Genetics

authors： Durrett RT,Chen KY,Tanksley SD

更新日期：2002-01-01 00:00:00

abstract：:Gene silencing mediated by dsRNA (RNAi) can persist for multiple generations in Caenorhabditis elegans (termed RNAi inheritance). Here we describe the results of a forward genetic screen in C. elegans that has identified six factors required for RNAi inheritance: GLH-1/VASA, PUP-1/CDE-1, MORC-1, SET-32, and two novel ...

journal_title：Genetics

authors： Spracklin G,Fields B,Wan G,Becker D,Wallig A,Shukla A,Kennedy S

更新日期：2017-07-01 00:00:00

abstract：:During development, the Notch receptor regulates many cell fate decisions by a signaling pathway that has been conserved during evolution. One positive regulator of Notch is Deltex, a cytoplasmic, zinc finger domain protein, which binds to the intracellular domain of Notch. Phenotypes resulting from mutations in delte...

journal_title：Genetics

authors： Cornell M,Evans DA,Mann R,Fostier M,Flasza M,Monthatong M,Artavanis-Tsakonas S,Baron M

更新日期：1999-06-01 00:00:00

abstract：:Dravet syndrome is a developmental epileptic encephalopathy caused by pathogenic variation in SCN1A To characterize the pathogenic substitution (p.H939R) of a local individual with Dravet syndrome, fibroblast cells from the individual were reprogrammed to pluripotent stem cells and differentiated into neurons. Sodium ...

journal_title：Genetics

authors： Dyment DA,Schock SC,Deloughery K,Tran MH,Ure K,Nutter LMJ,Creighton A,Yuan J,Banderali U,Comas T,Baumann E,Jezierski A,Care4Rare Canada Consortium,.,Boycott KM,Mackenzie AE,Martina M

更新日期：2020-08-01 00:00:00

abstract：:Two alternative hypotheses attribute different benefits to codon-anticodon adaptation. The first assumes that protein production is rate limited by both initiation and elongation and that codon-anticodon adaptation would result in higher elongation efficiency and more efficient and accurate protein production, especia...

journal_title：Genetics

authors： Xia X

更新日期：2015-02-01 00:00:00

abstract：:This FlyBook chapter summarizes the history and the current state of our understanding of the Wingless signaling pathway. Wingless, the fly homolog of the mammalian Wnt oncoproteins, plays a central role in pattern generation during development. Much of what we know about the pathway was learned from genetic and molec...

journal_title：Genetics

authors： Bejsovec A

更新日期：2018-04-01 00:00:00

abstract：:A novel method of RNA secondary structure prediction based on a comparison of nucleotide sequences is described. This method correctly predicts nearly all evolutionarily conserved secondary structures of five different RNAs: tRNA, 5S rRNA, bacterial ribonuclease P (RNase P) RNA, eukaryotic small subunit rRNA, and the ...

journal_title：Genetics

authors： Parsch J,Braverman JM,Stephan W

更新日期：2000-02-01 00:00:00

abstract：:It is well known that most new mutations that affect fitness exert deleterious effects and that natural populations are often composed of subpopulations (demes) connected by gene flow. To gain a better understanding of the joint effects of purifying selection and population structure, we focus on a scenario where an a...

journal_title：Genetics

authors： Zeng K,Corcoran P

更新日期：2015-12-01 00:00:00

abstract：:The term "micro-evo-devo" refers to the combined study of the genetic and developmental bases of natural variation in populations and the evolutionary forces that have shaped this variation. It thus represents a synthesis of the fields of evolutionary developmental biology and population genetics. As has been pointed ...

journal_title：Genetics

authors： Nunes MD,Arif S,Schlötterer C,McGregor AP

更新日期：2013-11-01 00:00:00

abstract：:We have identified two Saccharomyces cerevisiae genes that, in high copy, confer resistance to Kluyveromyces lactis zymocin, an inhibitor that blocks cells in the G(1) phase of the cell cycle prior to budding and DNA replication. One gene (GRX3) encodes a glutaredoxin and is likely to act at the level of zymocin entry...

journal_title：Genetics

authors： Jablonowski D,Butler AR,Fichtner L,Gardiner D,Schaffrath R,Stark MJ

更新日期：2001-12-01 00:00:00

abstract：:Automated image acquisition, a custom analysis algorithm, and a distributed computing resource were used to add time as a third dimension to a quantitative trait locus (QTL) map for plant root gravitropism, a model growth response to an environmental cue. Digital images of Arabidopsis thaliana seedling roots from two ...

journal_title：Genetics

authors： Moore CR,Johnson LS,Kwak IY,Livny M,Broman KW,Spalding EP

更新日期：2013-11-01 00:00:00

abstract：:This report examines five different naturally occurring alcohol dehydrogenase-1 alleles via the recombinational behavior of Adh1(-) mutants induced within them. Twenty-two biochemically characterized Adh1(-) mutants have been assessed for ability to recombine intragenically, using data generated by specifically staini...

journal_title：Genetics

authors： Freeling M

更新日期：1978-05-01 00:00:00

abstract：:The segregation and random assortment of characters observed by Mendel have their basis in the behavior of chromosomes in meiosis. But showing this actually to be the case requires a correct understanding of the meiotic behavior of chromosomes. This was achieved only gradually, over several decades, with much dispute ...

journal_title：Genetics

authors： Koszul R,Meselson M,Van Doninck K,Vandenhaute J,Zickler D

更新日期：2012-06-01 00:00:00

abstract：:Changes in genome structure and gene expression have been documented in both resynthesized and natural allopolyploids that contain two or more divergent genomes. The underlying mechanisms for rapid and stochastic changes in gene expression are unknown. Arabidopsis suecica is a natural allotetraploid derived from the e...

journal_title：Genetics

authors： Chen M,Ha M,Lackey E,Wang J,Chen ZJ

更新日期：2008-04-01 00:00:00

abstract：:We report the identification of bang senseless (bss), a Drosophila melanogaster mutant exhibiting seizure-like behaviors, as an allele of the paralytic (para) voltage-gated Na(+) (Na(V)) channel gene. Mutants are more prone to seizure episodes than normal flies because of a lowered seizure threshold. The bss phenotype...

journal_title：Genetics

authors： Parker L,Padilla M,Du Y,Dong K,Tanouye MA

更新日期：2011-02-01 00:00:00

abstract：:The RNA polymerase II (Pol-II) holoenzyme, responsible for messenger RNA production, typically consists of 10-12 subunits. Our laboratory previously demonstrated that maternally deposited, long, noncoding, template RNAs are essential for programmed genome rearrangements in the ciliate Oxytricha trifallax. Here we show...

journal_title：Genetics

authors： Khurana JS,Wang X,Chen X,Perlman DH,Landweber LF

更新日期：2014-07-01 00:00:00

abstract：:MiRNAs bear an increasing number of functions throughout development and in the aging adult. Here we address their role in establishing sexually dimorphic traits and sexual identity in male and female Drosophila. Our survey of miRNA populations in each sex identifies sets of miRNAs differentially expressed in male and...

journal_title：Genetics

authors： Fagegaltier D,König A,Gordon A,Lai EC,Gingeras TR,Hannon GJ,Shcherbata HR

更新日期：2014-10-01 00:00:00

abstract：:The mammalian GADD45 (growth arrest and DNA-damage inducible) gene family is composed of three highly homologous small, acidic, nuclear proteins: GADD45alpha, GADD45beta, and GADD45gamma. GADD45 proteins are involved in important processes such as regulation of DNA repair, cell cycle control, and apoptosis. Annotation...

journal_title：Genetics

authors： Peretz G,Bakhrat A,Abdu U

更新日期：2007-11-01 00:00:00

abstract：:Mutations affecting the self-incompatibility response of Nicotiana alata were generated by irradiation. Mutants in the M1 generation were selected on the basis of pollen tube growth through an otherwise incompatible pistil. Twelve of the 18 M1 plants obtained from the mutagenesis screen were self-compatible. Eleven se...

journal_title：Genetics

authors： Golz JF,Su V,Clarke AE,Newbigin E

更新日期：1999-07-01 00:00:00

abstract：:A total of 358 lys2 mutants of Saccharomyces cerevisiae have been characterized for suppressibility by the following suppressors: UAA and UAG suppressors that insert tyrosine, serine or leucine; a putative UGA suppressor; an omnipotent suppressor SUP46; and a frameshift suppressor SUF1-1. In addition, the lys2 mutants...

journal_title：Genetics

authors： Chattoo BB,Palmer E,Ono B,Sherman F

更新日期：1979-09-01 00:00:00

abstract：:Heterogeneous genetic divergence can accumulate across the genome when populations adapt to different habitats while still exchanging alleles. How long does diversification take and how much of the genome is affected? When divergence occurs in parallel from standing genetic variation, how often are the same haplotypes...

journal_title：Genetics

authors： Bassham S,Catchen J,Lescak E,von Hippel FA,Cresko WA

更新日期：2018-07-01 00:00:00

abstract：:Selection of Gl-Sb coupling heterozygotes was carried out for more than one hundred generations commencing with six independent lines drawn from a common base population. Population sizes were eight, sixteen and forty-eight parents per generation. The effect of natural selection on recombination value was measured by ...

journal_title：Genetics

authors： Kidwell MG

更新日期：1972-03-01 00:00:00

abstract：:The isozymic patterns of tyrosine aminotransferase, NADP malate dehydrogenase, NADP isocitrate dehydrogenase, and tetrazolium oxidase were examined by starch-gel electrophoresis in Tetrahymena pyriformis, syngen 1. The genetics of the alleles controlling these enzymes was studied through a breeding program. Each enzym...

journal_title：Genetics

authors： Borden D,Miller ET,Nanney DL,Whitt GS

更新日期：1973-08-01 00:00:00

abstract：:We have selected 210 mutants able to grow on sucrose in the presence of 2-deoxyglucose. We identified recessive mutations in three major complementation groups that cause constitutive (glucose-insensitive) secreted invertase synthesis. Two groups comprise alleles of the previously identified HXK2 and REG1 genes, and t...

journal_title：Genetics

authors： Neigeborn L,Carlson M

更新日期：1987-02-01 00:00:00

abstract：:Population structure leads to systematic patterns in measures of mean relatedness between individuals in large genomic data sets, which are often discovered and visualized using dimension reduction techniques such as principal component analysis (PCA). Mean relatedness is an average of the relationships across locus-s...

journal_title：Genetics

authors： Li H,Ralph P

更新日期：2019-01-01 00:00:00