ACTION OF A HISTIDINE ANALOGUE, 1,2,4-TRIAZOLE-3-ALANINE, IN SALMONELLA TYPHIMURIUM.

Abstract:

:Levin, Alfred P. (The Johns Hopkins University, Baltimore, Md.), and Philip E. Hartman. Action of a histidine analogue, 1,2,4-triazole-3-alanine, in Salmonella typhimurium. J. Bacteriol. 86:820-828. 1963.-The effect of the histidine analogue, 1,2,4-triazole-3-alanine (TRA), on growth and enzyme synthesis in histidine auxotrophs of Salmonella typhimurium has been studied. TRA allows an increase of approximately 50% in the amount of protein in a culture but does not allow concomitant synthesis of ribonucleic acid and deoxyribonucleic acid. Although the analogue prevents the formation of active bacteriophage and of enzymatically active inosine 5'-phosphate dehydrogenase, it does not prevent the formation of enzymatically active l-histidinol phosphate phosphatase or of imidazoleacetol phosphate transaminase, two enzymes involved in the biosynthesis of histidine. Of the three known functions of histidine in the cell, TRA mimics two: it is incorporated into protein, and it acts as a repressor material for synthesis of enzymes involved in the formation of histidine. TRA fails to act as a feedback inhibitor of the first step in the formation of histidine.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

LEVIN AP,HARTMAN PE

doi

10.1128/JB.86.4.820-828.1963

keywords:

subject

Has Abstract

pub_date

1963-10-01 00:00:00

pages

820-8

eissn

0021-9193

issn

1098-5530

journal_volume

86

pub_type

杂志文章
  • Genetic and phenotypic analyses of the rdx locus of Rhodobacter sphaeroides 2.4.1.

    abstract::Previously, we reported that rdxB, encoding a likely membrane-bound two [4Fe-4S]-containing center, is involved in the aerobic regulation of photosystem gene expression in Rhodobacter sphaeroides 2.4.1. To further investigate the role of rdxB as well as other genes of the rdxBHIS operon on photosystem gene expression,...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.182.12.3475-3481.2000

    authors: Roh JH,Kaplan S

    更新日期:2000-06-01 00:00:00

  • EFFECT OF 6-AMINONICOTINAMIDE ON CHICK-EMBRYO TISSUE CULTURES INFECTED WITH VACCINIA VIRUS.

    abstract::Lee, Spencer H. S. (Dalhousie University, Halifax, Nova Scotia). Effect of 6-aminonicotinamide on chick-embryo tissue cultures infected with vaccinia virus. J. Bacteriol. 88:885-892. 1964.-6-Aminonicotinamide (6-AN) was shown to render chick-embryo fibroblast (CEF) tissue cultures refractory to infection with vaccinia...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.88.4.885-892.1964

    authors: LEE SH

    更新日期:1964-10-01 00:00:00

  • Escherichia coli fimbriae recognizing sialyl galactosides.

    abstract::Fimbriae recognizing sialyl galactosides (S fimbriae) were purified from an Escherichia coli strain. The S fimbriae were morphologically identical to type 1 and P fimbriae of E. coli and showed a hemagglutination that was abolished when erythrocytes were treated with neuraminidase. Hemagglutination by the purified fim...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.159.2.762-766.1984

    authors: Korhonen TK,Väisänen-Rhen V,Rhen M,Pere A,Parkkinen J,Finne J

    更新日期:1984-08-01 00:00:00

  • Kinetics and catalytic properties of coenzyme A transferase from Peptostreptococcus elsdenii.

    abstract::Coenzyme A (CoA) transferase from Peptostreptococcus elsdenii was purified to homogeneity, and some of its physical and catalytic properties were determined. The native enzyme has a molecular weight of 181,000 and is composed of two alpha subunits (molecular weight, 65,000) and one beta subunit (molecular weight 50,00...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.128.1.372-381.1976

    authors: Schulman M,Valentino D

    更新日期:1976-10-01 00:00:00

  • Defining the region of Bacillus subtilis SpoIIIJ that is essential for its sporulation-specific function.

    abstract::Proteins of the YidC/OxaI/Alb3 family play a crucial role in the insertion, folding, and/or assembly of membrane proteins in prokaryotes and eukaryotes. Bacillus subtilis has two YidC-like proteins, denoted SpoIIIJ and YqjG. SpoIIIJ and YqjG are largely exchangeable in function, but SpoIIIJ has a unique role in sporul...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01084-13

    authors: Geng Y,de Keyzer J,Scheffers DJ,Driessen AJ

    更新日期:2014-04-01 00:00:00

  • Membrane-bound deoxyribonucleic acid from Escherichia coli: effects of replication, protein synthesis, and ribonucleic acid synthesis.

    abstract::The experiments presented in this paper suggest that the shift observed in sedimentation of deoxyribonucleic acid from cells of Escherichia coli subjected to amino acid starvation is related to inhibition of ribonucleic acid synthesis rather than to its release from the membrane at the termination of replication. ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.137.2.790-794.1979

    authors: Yaffe E,Grossman N,Ron EZ

    更新日期:1979-02-01 00:00:00

  • Temperature-sensitive, colicin M-tolerant mutant of Escherichia coli.

    abstract::A mutant sensitive to colicin M at 30 degrees C and tolerant at 42 degrees C to high concentrations of colicin M was isolated from Escherichia coli K-12. A temperature shift from 30 to 42 degrees C rescued all cells up to the time they started to lyse at 30 degrees C (25 min after addition of colicin M). The growth ra...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.147.1.135-139.1981

    authors: Schaller K,Krauel A,Braun V

    更新日期:1981-07-01 00:00:00

  • Purification and characterization of a 14-kilodalton protein that is bound to the surface of polyhydroxyalkanoic acid granules in Rhodococcus ruber.

    abstract::The N-terminal amino acid sequence of the polyhydroxyalkanoic acid (PHA) granule-associated M(r)-15,500 protein of Rhodococcus ruber (the GA14 protein) was analyzed. The sequence revealed that the corresponding structural gene is represented by open reading frame 3, encoding a protein with a calculated M(r) of 14,175 ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.176.14.4328-4337.1994

    authors: Pieper-Fürst U,Madkour MH,Mayer F,Steinbüchel A

    更新日期:1994-07-01 00:00:00

  • Enterohemolysin production is associated with a temperate bacteriophage in Escherichia coli serogroup O26 strains.

    abstract::A temperate bacteriophage that determines the expression of enterohemolysin was isolated from Escherichia coli O26 strain C3888. The genetic determinant associated with enterohemolysin production (E-Hly determinant) was cloned from EcoRI-digested bacteriophage DNA in vector plasmid pUC8. pUC8 recombinant plasmid pEO19...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.172.11.6469-6475.1990

    authors: Beutin L,Bode L,Ozel M,Stephan R

    更新日期:1990-11-01 00:00:00

  • The elastic properties of the caulobacter crescentus adhesive holdfast are dependent on oligomers of N-acetylglucosamine.

    abstract::The aquatic bacterium Caulobacter crescentus attaches to solid surfaces through an adhesive holdfast located at the tip of its polar stalk, a thin cylindrical extension of the cell membrane. In this paper, the elastic properties of the C. crescentus stalk and holdfast assembly were studied by using video light microsc...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.187.1.257-265.2005

    authors: Li G,Smith CS,Brun YV,Tang JX

    更新日期:2005-01-01 00:00:00

  • Bradyrhizobium japonicum glnB, a putative nitrogen-regulatory gene, is regulated by NtrC at tandem promoters.

    abstract::The glnB gene from Bradyrhizobium japonicum, the endosymbiont of soybeans (Glycine max), was isolated and sequenced, and its expression was examined under various culture conditions and in soybean nodules. The B. japonicum glnB gene encodes a 12,237-dalton polypeptide that is highly homologous to the glnB gene product...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.171.10.5638-5645.1989

    authors: Martin GB,Thomashow MF,Chelm BK

    更新日期:1989-10-01 00:00:00

  • Function of the sigma(E) regulon in dead-cell lysis in stationary-phase Escherichia coli.

    abstract::Elevation of active sigma(E) levels in Escherichia coli by either repressing the expression of rseA encoding an anti-sigma(E) factor or cloning rpoE in a multicopy plasmid, led to a large decrease in the number of dead cells and the accumulation of cellular proteins in the medium in the stationary phase. The numbers o...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.182.18.5231-5237.2000

    authors: Nitta T,Nagamitsu H,Murata M,Izu H,Yamada M

    更新日期:2000-09-01 00:00:00

  • Molecular cloning and sequencing of the gene encoding the fimbrial subunit protein of Bacteroides gingivalis.

    abstract::The gene encoding the fimbrial subunit protein of Bacteroides gingivalis 381, fimbrilin, has been cloned and sequenced. The gene was present as a single copy on the bacterial chromosome, and the codon usage in the gene conformed closely to that expected for an abundant protein. The predicted size of the mature protein...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.170.4.1658-1665.1988

    authors: Dickinson DP,Kubiniec MA,Yoshimura F,Genco RJ

    更新日期:1988-04-01 00:00:00

  • Role of CodY in regulation of the Bacillus subtilis hut operon.

    abstract::Bacillus subtilis mutants deficient in amino acid repression of the histidine utilization (hut) operon were isolated by transposon mutagenesis. Genetic characterization of these mutants indicated that they most likely contained transposon insertions within the codVWXY operon. The codY gene is required for nutritional ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.178.13.3779-3784.1996

    authors: Fisher SH,Rohrer K,Ferson AE

    更新日期:1996-07-01 00:00:00

  • RNase E affects the expression of the acyl-homoserine lactone synthase gene sinI in Sinorhizobium meliloti.

    abstract::Quorum sensing of Sinorhizobium meliloti relies on N-acyl-homoserine lactones (AHLs) as autoinducers. AHL production increases at high population density, and this depends on the AHL synthase SinI and two transcriptional regulators, SinR and ExpR. Our study demonstrates that ectopic expression of the gene rne, coding ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01471-13

    authors: Baumgardt K,Charoenpanich P,McIntosh M,Schikora A,Stein E,Thalmann S,Kogel KH,Klug G,Becker A,Evguenieva-Hackenberg E

    更新日期:2014-04-01 00:00:00

  • CHARACTERISTICS OF CLOSTRIDIUM PERFRINGENS STRAINS ASSOCIATED WITH FOOD AND FOOD-BORNE DISEASE.

    abstract::Hall, Herbert E. (Robert A. Taft Sanitary Engineering Center, Cincinnati, Ohio), Robert Angelotti, Keith H. Lewis, and Milton J. Foter. Characteristics of Clostridium perfringens strains associated with food and food-borne disease. J. Bacteriol. 85:1094-1103. 1963.-A total of 83 strains of Clostridium perfringens-30 f...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.85.5.1094-1103.1963

    authors: HALL HE,ANGELOTTI R,LEWIS KH,FOTER MJ

    更新日期:1963-05-01 00:00:00

  • Analysis of DNA inversions in the shufflon of plasmid R64.

    abstract::The shufflon, a multiple DNA inversion system in the plasmid R64, consists of four DNA segments flanked and separated by seven 19-bp repeat sequences. Site-specific recombinations mediated by the rci product occur between each inverted repeat sequence, resulting in inversions of the four segments independently or in g...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.179.6.1867-1871.1997

    authors: Gyohda A,Funayama N,Komano T

    更新日期:1997-03-01 00:00:00

  • Cloning and characterization of argR, a gene that participates in regulation of arginine biosynthesis and catabolism in Pseudomonas aeruginosa PAO1.

    abstract::Gel retardation experiments indicated the presence in Pseudomonas aeruginosa cell extracts of an arginine-inducible DNA-binding protein that interacts with the control regions for the car and argF operons, encoding carbamoylphosphate synthetase and anabolic ornithine carbamoyltransferase, respectively. Both enzymes ar...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.179.17.5300-5308.1997

    authors: Park SM,Lu CD,Abdelal AT

    更新日期:1997-09-01 00:00:00

  • ORGANIC REQUIREMENTS AND SYNTHETIC MEDIA FOR GROWTH OF THE MYXOMYCETE PHYSARUM POLYCEPHALUM.

    abstract::Daniel, John W. (University of Wisconsin, Madison), Karlee L. Babcock, Alice H. Sievert, and Harold P. Rusch. Organic requirements and synthetic media for growth of the myxomycete Physarum polycephalum. J. Bacteriol. 86:324-331. 1963.-An isolate of Physarum polycephalum was maintained in submersed pure culture in a co...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.86.2.324-331.1963

    authors: DANIEL JW,BABCOCK KL,SIEVERT AH,RUSCH HP

    更新日期:1963-08-01 00:00:00

  • Control of cell growth in bacteria: experiments with thymine starvation.

    abstract::When cells of Escherichia coli THU were starved for thymine, they continued to grow without division for at least two successive volume doublings at their initial rate. Within experimental error this average rate of volume increase, 0.21 mum(3) per hr, was identical with that observed in control cultures during two ge...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.105.2.472-476.1971

    authors: Kubitschek HE

    更新日期:1971-02-01 00:00:00

  • Purification of Helicobacter pylori NCTC 11637 cytochrome bc1 and respiration with D-proline as a substrate.

    abstract::Helicobacter pylori is a microaerophilic bacterium associated with gastric inflammation and peptic ulcers. Knowledge of how pathogenic organisms produce energy is important from a therapeutic point of view. We found d-amino acid dehydrogenase-mediated electron transport from d-proline or d-alanine to oxygen via the re...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01111-09

    authors: Tanigawa M,Shinohara T,Nishimura K,Nagata K,Ishizuka M,Nagata Y

    更新日期:2010-03-01 00:00:00

  • Abortive phage resistance mechanism AbiZ speeds the lysis clock to cause premature lysis of phage-infected Lactococcus lactis.

    abstract::The conjugative plasmid pTR2030 has been used extensively to confer phage resistance in commercial Lactococcus starter cultures. The plasmid harbors a 16-kb region, flanked by insertion sequence (IS) elements, that encodes the restriction/modification system LlaI and carries an abortive infection gene, abiA. The AbiA ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.00904-06

    authors: Durmaz E,Klaenhammer TR

    更新日期:2007-02-01 00:00:00

  • Distribution of polyamines in methanogenic bacteria.

    abstract::Members of all four families of methanogenic bacteria were analyzed for polyamine concentrations. High-performance liquid chromatography analysis of dansylated cell extracts revealed typical polyamine patterns for each family. Members of Methanobacteriaceae (family I) were characterized by very low polyamine concentra...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.154.3.1315-1322.1983

    authors: Scherer P,Kneifel H

    更新日期:1983-06-01 00:00:00

  • Identification by genetic suppression of Escherichia coli TolB residues important for TolB-Pal interaction.

    abstract::The Tol-Pal system of Escherichia coli is involved in maintaining outer membrane stability. Mutations in tolQ, tolR, tolA, tolB, or pal genes result in sensitivity to bile salts and the leakage of periplasmic proteins. Moreover, some of the tol genes are necessary for the entry of group A colicins and the DNA of filam...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.182.3.821-824.2000

    authors: Ray MC,Germon P,Vianney A,Portalier R,Lazzaroni JC

    更新日期:2000-02-01 00:00:00

  • Uric acid utilization by Mycobacterium intracellulare and Mycobacterium scrofulaceum isolates.

    abstract::Forty-nine human and environmental isolates of Mycobacterium intracellulare and Mycobacterium scrofulaceum were tested for their ability to grow on uric acid and a number of its degradation products. Nearly all (88 to 90%) strains used uric acid or allantoin as a sole nitrogen source; fewer (47 to 69%) used allantoate...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.155.1.36-39.1983

    authors: Falkinham JO 3rd,George KL,Parker BC,Gruft H

    更新日期:1983-07-01 00:00:00

  • Physiological studies of the regulation of beta-lactamase expression in Pseudomonas maltophilia.

    abstract::The kinetics of beta-lactamase induction in Pseudomonas maltophilia IID1275/873 were investigated. Upon induction with beta-lactam antibiotics, a correlation was seen between the increase in specific beta-lactamase activity and the generation time, as well as the concentration of inducer in the medium. The specific be...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.171.1.483-487.1989

    authors: Rosta S,Mett H

    更新日期:1989-01-01 00:00:00

  • Physiological effects of anti-TRAP protein activity and tRNA(Trp) charging on trp operon expression in Bacillus subtilis.

    abstract::The Bacillus subtilis anti-TRAP protein regulates the ability of the tryptophan-activated TRAP protein to bind to trp operon leader RNA and promote transcription termination. AT synthesis is regulated both transcriptionally and translationally by uncharged tRNA(Trp). In this study, we examined the roles of AT synthesi...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01820-07

    authors: Cruz-Vera LR,Gong M,Yanofsky C

    更新日期:2008-03-01 00:00:00

  • ACTION OF FORMALDEHYDE ON MICROORGANISMS. I. CORRELATION OF ACTIVITY WITH FORMALDEHYDE METABOLISM.

    abstract::Neely, W. Brock (The Dow Chemical Co., Midland, Mich.). Action of formaldehyde on microorganisms. I. Correlation of activity with formaldehyde metabolism. J. Bacteriol. 85:1028-1031. 1963.-The action of formaldehyde in concentrations sublethal for the culture appeared to be at least twofold. The first phase caused a d...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.85.5.1028-1031.1963

    authors: NEELY WB

    更新日期:1963-05-01 00:00:00

  • Effect of iron on accumulation of exotoxin A-specific mRNA in Pseudomonas aeruginosa.

    abstract::A DNA probe from an internal fragment of the exotoxin A structural gene was used to study the effects of selected culture conditions on steady-state levels of exotoxin-specific mRNA in Pseudomonas aeruginosa. Cells grown under conditions of iron deprivation began to synthesize and excrete the exotoxin A polypeptide du...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.168.3.1451-1456.1986

    authors: Lory S

    更新日期:1986-12-01 00:00:00

  • Molecular cloning of structural and immunity genes for megacins A-216 and A-19213 in Bacillus megaterium.

    abstract::A host-vector system was developed for molecular cloning in Bacillus megaterium and used to clone the structural and immunity genes for megacins A-216 and A-19213. Recombinant clones that expressed immunity only or both immunity to and production of each megacin were obtained. Restriction mapping of native megacinogen...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.160.3.854-859.1984

    authors: Von Tersch MA,Carlton BC

    更新日期:1984-12-01 00:00:00