INTRACELLULAR M PROTEIN OF GROUP A STREPTOCOCCUS.

Abstract:

:Fox, Eugene N. (University of Chicago, Chicago, Ill.). Intracellular M protein of group A Streptococcus. J. Bacteriol. 85:536-540. 1963.-A heat-labile M protein antigen in protoplasts of a type 14 strain of group A Streptococcus has been demonstrated in a soluble form in the cytoplasm, and also bound to the protoplasmic membrane. When trypsinized whole cells (from which the M protein on the cell wall had been digested) or protoplasts were extracted with hot HCl, no M protein antigen was detected, although the antigen was routinely extracted from the cell walls of normal streptococci by the hot acid procedure. Various serological techniques, including the use of fluorescein-labeled type-specific antisera, were employed to demonstrate the M antigen in association with the membrane from osmotically lysed protoplasts.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

FOX EN

doi

10.1128/JB.85.3.536-540.1963

keywords:

subject

Has Abstract

pub_date

1963-03-01 00:00:00

pages

536-40

eissn

0021-9193

issn

1098-5530

journal_volume

85

pub_type

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