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Resistance to collagen-induced arthritis in Biozzi mice is not associated with a defect in autoantibodies to accessible epitopes on cartilage collagen.

Abstract：

:In order to understand why most strains of Biozzi mice are unexpectedly either arthritis-resistant, or susceptible, we investigate the autoantibody reactivity against matrix-embedded collagen molecules. We show a close correlation between these tissular and the free collagen antibodies, irrespective of arthritis susceptibility. These results are against an antibody response restricted to hidden non-pathogenic epitopes in the resistant mice.

journal_name

Scand J Immunol

journal_title

Scandinavian journal of immunology

authors

Bouvet JP,Franc B,Zyad A,Couderc J

doi

10.1111/j.1365-3083.1992.tb02974.x

keywords:

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

677-80

issue

6

eissn

0300-9475

issn

1365-3083

journal_volume

35

pub_type

杂志文章

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