Korean nationwide surveillance of antimicrobial resistance in 2000 with special reference to vancomycin resistance in enterococci, and expanded-spectrum cephalosporin and imipenem resistance in gram-negative bacilli.

Abstract:

:Antimicrobial resistance surveillance is necessary to determine the size of the problem and to guide empirical selection of antimicrobial agents for treating infected patients. The aim of this study was to analyze the results of susceptibility tests performed by hospitals participating in the Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) program. The rates of oxacillin-resistant staphylococci, penicillin-nonsusceptible pneumococci, and ampicillin-resistant E. faecium were over 70%. Ampicillin-resistant H. influenzae increased to 68%. Expanded-spectrum cephalosporin-resistant K. pneumoniae, fluoroquinolone-resistant E. coli, and imipenem-resistant P. aeruginosa remained at 16% through 27%, depending on the species. The proportions of vancomycin- resistant E. faecium and imipenem-resistant P. aeruginosa were 18 - 24% and 19-21%, respectively, indicating the seriousness of antimicrobial resistance. In conclusion, the increasing prevalence of resistant bacteria indicates that more concerted effort is required to conserve the usefulness of precious new antimicrobial agents.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Lee KW,Kim MY,Kang SH,Kang JO,Kim EC,Choi TY,Chong YS,Korean Nationwide Surveillance Of Antimicrobial Resistance Group.

doi

10.3349/ymj.2003.44.4.571

keywords:

subject

Has Abstract

pub_date

2003-08-30 00:00:00

pages

571-8

issue

4

eissn

0513-5796

issn

1976-2437

pii

200308571

journal_volume

44

pub_type

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