Intra-synovial ropivacaine and morphine for pain relief after total knee arthroplasty: a prospective, randomized, double blind study.

Abstract:

PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal groups (n=30). Demographic data, including age, height, weight, knee score, visual analogue scale (VAS), and range of flexion were evaluated preoperatively. Before wound closure, patients were given intra-synovial injections of the following solutions: patients in group I received 40mL of 300mg ropivacaine with 1:200,000 epinephrine and 5mg morphine; patients in Group II received 40mL of 300mg ropivacaine with epinephrine; and patients in Group III received 50mL normal saline as a control. All patients received an epidural patient-controlled analgesia (PCA) for 24 postoperative hours. Analgesic efficacy was evaluated using the VAS at intervals of 2, 4, 6, 12, 24, 32, 40, and 48 hours postoperatively. During this period, the side effects, the dosage of rescue analgesia required, and the range of knee flexion were recorded for each group. RESULTS:There were no significant differences among the three groups with regards to the VAS and the required dose of rescue analgesia (p > 0.05). None of the groups demonstrated significant differences in the range of knee flexion and the incidence of postoperative nausea and emesis (p > 0.05). CONCLUSION:Therefore, we found that ropivacaine, alone or with morphine, injected into the synovial tissue, along with an epidural PCA has no additional benefits in pain control after a total knee arthroplasty.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Han CD,Lee DH,Yang IH

doi

10.3349/ymj.2007.48.2.295

subject

Has Abstract

pub_date

2007-04-30 00:00:00

pages

295-300

issue

2

eissn

0513-5796

issn

1976-2437

pii

200704295

journal_volume

48

pub_type

杂志文章,随机对照试验
  • Pleural epithelioid hemangioendothelioma.

    abstract::Epithelioid hemangioendothelioma (EHE) is a rare tumor of vascular origin. While it can be found in any tissue, it is most often found in lung and liver and usually has an intermediate behavior. EHEs originating from pleural tissue have been less frequently described than those from other sites. Furthermore, to date, ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2008.49.6.1036

    authors: Lee YJ,Chung MJ,Jeong KC,Hahn CH,Hong KP,Kim YJ,Kim YT

    更新日期:2008-12-31 00:00:00

  • Predictors of thyroid gland involvement in hypopharyngeal squamous cell carcinoma.

    abstract:PURPOSE:Decision to perform concurrent ipsilateral thyroidectomy on patients with hypopharyngeal cancer is important, and unnecessary thyroidectomy should be avoided if oncologically feasible. We hypothesized that concurrent ipsilateral thyroidectomy is not routinely required to prevent occult metastasis. This study ai...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.3.812

    authors: Chang JW,Koh YW,Chung WY,Hong SW,Choi EC

    更新日期:2015-05-01 00:00:00

  • Role of different peripheral components in the expression of neuropathic pain syndrome.

    abstract::Peripheral nerve injury frequently leads to neuropathic pain like hyperalgesia, spontaneous pain, mechanical allodynia, thermal allodynia. It is uncertain where the neuropathic pain originates and how it is transmitted to the central nervous system. This study was performed in order to determine which peripheral compo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2000.41.3.354

    authors: Won R,Lee BH,Park S,Kim SH,Park YG,Chung SS

    更新日期:2000-06-01 00:00:00

  • Coronary Artery Aneurysm after Second-Generation Drug-Eluting Stent Implantation.

    abstract:PURPOSE:We evaluated the incidence, predictors, and prognosis of coronary artery aneurysm (CAA) after second-generation drug-eluting stent (DES) implantation. MATERIALS AND METHODS:A total of 976 consecutive patients (1245 lesions) who underwent follow-up angiography after second-generation DES implantation were analy...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2019.60.9.824

    authors: Hong SJ,Kim H,Ahn CM,Kim JS,Kim BK,Ko YG,Hong BK,Choi D,Jang Y,Hong MK

    更新日期:2019-09-01 00:00:00

  • Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma.

    abstract::A 71-year-old man was stable on warfarin (2.25 mg daily) therapy with an international normalized ratio (INR) of 1.8-2.2 after a heart valve replacement surgery. Recently, he consumed the liquid-like herbal product called shengmai-yin (10 mL daily) against medical advice. Seven days after the daily consumption of shen...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.5.793

    authors: Su Q,Li Y

    更新日期:2010-09-01 00:00:00

  • A comparison of estrogen and two different doses of calcitonin in ovariectomized rats.

    abstract::The purpose of this study was to investigate the treatment efficacies of salmon calcitonin (SC) and estrogen in a type-I osteoporotic rat model. Sixty, 3-month-old, female Wistar rats were divided into six groups. The first group was used as the control, and the second a sham, the other four were surgically ovariectom...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.3.508

    authors: Kavuncu V,Sahin S,Baydas G,Ilhan N,Ozercan I,Yasar A,Pekkutucu I,Ilhan N,Ozercan R

    更新日期:2003-06-30 00:00:00

  • Renal involvement of chronic myelogenous leukemia presenting as a kidney tumor.

    abstract::Renal involvement by leukemic cells is rare in chronic myelogenous leukemia (CML). Herein, this study reports a case of CML associated with renal involvement of leukemic cells, which occurred 1 and 1/2 years after the initial diagnosis. Abdomino-pelvic computed tomography revealed a 4.4 x 4.2 cm-sized, low-density sol...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.5.944

    authors: Go JH

    更新日期:2004-10-31 00:00:00

  • Beneficial effects of stroke-unit care in stroke patients with atrial fibrillation.

    abstract:PURPOSE:Continuous cardiac monitoring in a stroke unit (SU) may improve detection of atrial fibrillation (AF), and SU care may improve the rate of anticoagulation by better adherence to a standardized treatment protocol in patients with AF. We investigated the effects of the SU on the detection of AF and the rate of wa...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.2.301

    authors: Choi HY,Seo JH,Yang JH,Kim YD,Jung YH,Cho HJ,Nam HS,Heo JH

    更新日期:2013-03-01 00:00:00

  • The fibrinogen degradation products (FgDP) levels in liver disease.

    abstract::We measured plasma levels of fibrinogen degradation products (FgDP) with newly developed enzyme-linked immunosorbent assay based on monoclonal antibody to assess the fibrinogenolytic state in 52 patients with various liver diseases (27 patients with liver cirrhosis, 10 with chronic hepatitis, 7 with acute hepatitis, 6...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1993.34.3.234

    authors: Song KS,Kim HS,Park KE,Kwon OH

    更新日期:1993-09-01 00:00:00

  • Sclerosing hemangioma with lymph node metastasis.

    abstract::Sclerosing hemangioma (SH) of the lung is an uncommon type of tumor, which is composed of polygonal and cuboidal cells. This disease is generally regarded as benign but extremely rare cases with lymph node metastasis have been reported. We report a case of SH with a metastasis to the regional lymph nodes. A 19-year-ol...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.1.150

    authors: Kim KH,Sul HJ,Kang DY

    更新日期:2003-02-01 00:00:00

  • Morphological characteristics of the developing human brain during the embryonic period.

    abstract::Many features of the developing nervous system are visible from external observations of intact human embryos. In this study, a photographic atlas from the 4th to the 7th week after ovulation (Carnegie stages 10-18) is provided. The neural folds began to fuse at stage 10, and the rostral and caudal neuropore were clos...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.1.26

    authors: Yoon H,Shin YS,Lee KC,Park HW

    更新日期:1997-02-01 00:00:00

  • Oocyte maturity in relation to woman's age in in vitro fertilization cycles stimulated by single regimen.

    abstract:PURPOSE:During stimulated in vitro fertilization (IVF) cycle, up to 30% of the recovered oocytes are immature ones which have poor fertilization capacity; however, the precise influencing factors are largely unknown. Here, we analyzed the association of oocyte immaturity with woman's age in IVF cycles stimulated by sin...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.1.181

    authors: Lee HJ,Jee BC,Suh CS,Kim SH,Moon SY

    更新日期:2012-01-01 00:00:00

  • Coronary Stent Infection Presented as Recurrent Stent Thrombosis.

    abstract::Percutaneous transluminal coronary angioplasty with metal stent placement has become a well-developed treatment modality for coronary stenotic lesions. Although infection involving implanted stents is rare, it can, however, occur with high morbidity and mortality. We describe herein a case of an inserted coronary sten...

    journal_title:Yonsei medical journal

    pub_type:

    doi:10.3349/ymj.2017.58.2.458

    authors: Lai CH,Lin YK,Lee WL,Chang WC

    更新日期:2017-03-01 00:00:00

  • Diagnosis of overt disseminated intravascular coagulation: a comparative study using criteria from the International Society versus the Korean Society on Thrombosis and Hemostasis.

    abstract:PURPOSE:Since 1993, Koreans have used diagnostic criteria set by the Korean Society on Thrombosis and Hemostasis (KSTH) in the diagnosis of overt disseminated intravascular coagulation (DIC). In 2001, the Scientific and Standardization Committee (SCC) of the International Society on Thrombosis and Hemostasis (ISTH) pro...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.4.595

    authors: Lee JH,Song JW,Song KS

    更新日期:2007-08-31 00:00:00

  • Nonspecific interstitial pneumonitis after bortezomib and thalidomide treatment in a multiple myeloma patient.

    abstract::Bortezomib, an inhibitor of 26S proteosome, is recently approved treatment option for multiple myeloma. Thalidomide, a drug with immunomodulating and antiangiogenic effects, has also shown promise as an effective treatment in multiple myeloma. Pulmonary complications are believed to be rare, especially interstitial lu...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.3.448

    authors: Kang W,Kim JS,Cho SH,Kim SK,Chang J,Park MS

    更新日期:2010-05-01 00:00:00

  • α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells.

    abstract::The epithelial cytokine response, associated with reactive oxygen species (ROS), is important in Helicobacter pylori (H. pylori)-induced inflammation. H. pylori induces the production of ROS, which may be involved in the activation of mitogen-activated protein kinases (MAPK), janus kinase/signal transducers and activa...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.1.260

    authors: Choi JH,Cho SO,Kim H

    更新日期:2016-01-01 00:00:00

  • Rapid prenatal diagnosis of trisomy 21 by real-time quantitative polymerase chain reaction with amplification of small tandem repeats and S100B in chromosome 21.

    abstract::Trisomy 21 (Down syndrome) is the most common congenital anomaly, and it occurs in one out of 700-1000 births. Current techniques such as amniocentesis and chorionic villi sampling (CVS) require lengthy laboratory culture procedures and high costs. This study was undertaken to establish a rapid prenatal diagnosis of t...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.2.193

    authors: Yang YH,Nam MS,Yang ES

    更新日期:2005-04-30 00:00:00

  • Molecular analysis of fluoroquinolone-resistance in Escherichia coli on the aspect of gyrase and multiple antibiotic resistance (mar) genes.

    abstract::We analyzed the fluoroquinolone resistance mechanism of 28 isolates of ciprofloxacin-resistant E. coli from patients who received ciprofloxacin as a regimen of a selective gut decontamination. Isolates distinctive by infrequent restriction site polymerase chain reaction (IRS-PCR) were subjected to Hinf I restriction f...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1998.39.6.534

    authors: Park YH,Yoo JH,Huh DH,Cho YK,Choi JH,Shin WS

    更新日期:1998-12-01 00:00:00

  • The effect of sodium cromoglycate on the induction of experimental IgA nephropathy.

    abstract::Mesangial IgA nephropathy was experimentally induced in ddY mice by oral and parenteral administration of the poliomyelitis vaccine (POLIO), and we then tried to investigate if IgA deposition could be prevented by the concurrent use of sodium cromoglycate (SCG), which is known to inhibit the local mucosal immune react...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1990.31.1.33

    authors: Jin SY,Choi IJ

    更新日期:1990-03-01 00:00:00

  • Drug attitude and adherence to anti-glaucoma medication.

    abstract:PURPOSE:The purpose of this study is to assess patient attitudes towards anti-glaucoma medication and their association with adherence, visual quality of life, and personality traits. MATERIALS AND METHODS:One hundred and forty-seven glaucoma patients were enrolled this study. The participants were divided into 'pharm...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.2.261

    authors: Hong S,Kang SY,Yoon JU,Kang U,Seong GJ,Kim CY

    更新日期:2010-03-01 00:00:00

  • Angiotensinogen and angiotensin II type 1 receptor gene polymorphism in patients with autosomal dominant polycystic kidney disease: effect on hypertension and ESRD.

    abstract::Autosomal dominant polycystic kidney disease (ADPKD), a common genetic disease, is characterized by the development of hypertension and end stage renal disease. An increase in the activity of the renin-angiotensin system, due to a renal ischemia caused by cyst expansion, contributes to the development of hypertension ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.4.641

    authors: Lee KB,Kim UK

    更新日期:2003-08-30 00:00:00

  • Associations for BCO2, PCSK9, and TR1B1 Polymorphism and Lifestyle Factors with Ischemic Stroke: A Nested Case-Control Study.

    abstract:PURPOSE:To investigate associations for polymorphisms in β-carotene 9',10'-oxygenase (BCO2, rs10431036 and rs11214109), proprotein convertase subtilisin kexin type 9 (PCSK9, rs11583680), and tribbles pseudokinase 1 (TRIB1, rs17321515 and rs2954029), as well as lifestyle factors, with ischemic stroke (IS). MATERIALS AN...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2019.60.7.659

    authors: Zhao TY,Li Z,Lei S,Huang L,Yang L

    更新日期:2019-07-01 00:00:00

  • NUP210 and MicroRNA-22 Modulate Fas to Elicit HeLa Cell Cycle Arrest.

    abstract:PURPOSE:Cervical cancer is one of the most fatal diseases among women in under-developed countries. To improve cervical cancer treatment, discovery of new targets is needed. In this study, we investigated the expression of NUP210, miR-22, and Fas in cervical cancer tissues and their functions in cell cycle regulation. ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2020.61.5.371

    authors: Gu Q,Hou W,Liu H,Shi L,Zhu Z,Ye W,Ni X

    更新日期:2020-05-01 00:00:00

  • Subdiaphragmatic vagotomy induces NADPH diaphorase in the rat dorsal motor nucleus of the vagus.

    abstract::Axotomy of the vagal motor neurons by cervical vagotomy induces NADPH diaphorase staining due to increased nitric oxide synthase expression in both the rat dorsal motor nucleus and nucleus ambiguous; furthermore, cerical vagotomy leads to cell death of the dorsal motor nucleus cells. Subdiaphragmatic vagotomy axotomiz...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2001.42.2.215

    authors: Jahng JW,Kim DG,Houpt TA

    更新日期:2001-04-01 00:00:00

  • Coronary-subclavian steal syndrome presenting with ventricular tachycardia.

    abstract::Coronary-subclavian steal through the left internal mammary graft is a rare cause of myocardial ischemia in patients who have had a coronary bypass surgery. We report a 70-year-old man who presented with sustained monomorphic ventricular tachycardia 5 years after the surgical creation of a left internal mammary to the...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.6.852

    authors: Kursaklioglu H,Kose S,Iyisoy A,Amasyali B,Celik T,Aytemir K,Isik E

    更新日期:2009-12-31 00:00:00

  • Neurologic recovery according to the spinal fracture patterns by Denis classification.

    abstract:PURPOSE:Although Denis classification is considered as one of most clinically useful schemes for the evaluation of spinal fracture, there is little documentation on the relationship between fracture pattern and the neurologic recovery. The purpose is to evaluate the correlation between the fracture patterns according t...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.3.715

    authors: Park MS,Moon SH,Yang JH,Lee HM

    更新日期:2013-05-01 00:00:00

  • Sex difference of type 2 diabetes affected by abdominal obesity versus overall obesity.

    abstract:PURPOSE:This research compares the predictive value of the abdominal obesity indicator, waist circumference (WC), and the overall obesity indicator, body mass index (BMI), among men and women with regard to type 2 diabetes. MATERIALS AND METHODS:This study used data collected from 4,400 households selected by a strati...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.6.850

    authors: Paek KW,Chun KH

    更新日期:2010-11-01 00:00:00

  • Rarity of TLR4 Asp299Gly and Thr399Ile polymorphisms in the Korean population.

    abstract:PURPOSE:Activation of the innate immune system and chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and also thought to be associated with type 2 diabetes and its complications. As a receptor for bacterial lipopolysaccharide and heat-shock proteins, Toll-like receptor 4 (...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.1.58

    authors: Kim YS,Hwang YJ,Kim SY,Yang SM,Lee KY,Park IeB

    更新日期:2008-02-29 00:00:00

  • Erratum to "Diagnostic Algorithm to Reflect Regressive Changes of Human Papilloma Virus in Tissue Biopsies" by Lhee MJ, et al. (Yonsei Med J 2014;55:331-338.).

    abstract::This corrects the article on p. 331 in vol. 55, PMID: 24532500. ...

    journal_title:Yonsei medical journal

    pub_type: 已发布勘误

    doi:10.3349/ymj.2017.58.5.1081

    authors:

    更新日期:2017-09-01 00:00:00

  • Polypoidal choroidal vasculopathy in Korean patients with large submacular hemorrhage.

    abstract:PURPOSE:To determine and compare the clinical characteristics, visual prognosis and treatment of hemorrhagic polypoidal choroidal vasculopathy (HPCV) with those of hemorrhagic choroidal neovascularization (HCNV) due to age-related macular degeneration (ARMD). MATERIALS AND METHODS:Retrospective analysis of 44 consecut...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.2.225

    authors: Yoon JS,Lee J,Lee SC,Koh HJ,Kim SS,Kwon OW

    更新日期:2007-04-30 00:00:00