The fibrinogen degradation products (FgDP) levels in liver disease.

Abstract:

:We measured plasma levels of fibrinogen degradation products (FgDP) with newly developed enzyme-linked immunosorbent assay based on monoclonal antibody to assess the fibrinogenolytic state in 52 patients with various liver diseases (27 patients with liver cirrhosis, 10 with chronic hepatitis, 7 with acute hepatitis, 6 with hepatocellular carcinoma, 2 with intrahepatic cholestasis). As compared with 20 healthy subjects (upper limit: 580 ng/ml), elevated plasma levels (660-32000 ng/ml) of FgDP were found in 19 (36.5%) patients. When analyzed according to the underlying disease categories, the magnitude of elevations of FgDP were most prominent in patients with chronic hepatitis. No correlation was found between plasma FgDP levels and serum AST or ALT activity. These findings indicate that increased primary fibrinogenolysis is not rare in liver disease, but poorly correlates with liver function.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Song KS,Kim HS,Park KE,Kwon OH

doi

10.3349/ymj.1993.34.3.234

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

234-8

issue

3

eissn

0513-5796

issn

1976-2437

journal_volume

34

pub_type

杂志文章
  • Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines.

    abstract:PURPOSE:This study aimed to investigate whether Müllerian inhibiting substance (MIS) in combination with calcitriol modulates proliferation and apoptosis of human ovarian cancer (OCa) cell lines (SKOV3, OVCAR3, and OVCA433) and identify the signaling pathway by which MIS mediates apoptosis. MATERIALS AND METHODS:OCa c...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.1.33

    authors: Jung YS,Kim HJ,Seo SK,Choi YS,Nam EJ,Kim S,Kim SW,Han HD,Kim JW,Kim YT

    更新日期:2016-01-01 00:00:00

  • A case of superficial epithelioma with sebaceous differentiation.

    abstract::Superficial epithelioma with sebaceous differentiation (SESD) is a rare benign neoplasm with peculiar histopathologic characteristics, which occurs in aged skin. We report upon a case of SESD occurring on the left upper back, which histopathologically is a superficial, multilobular tumor with numerous basaloid cells m...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.2.347

    authors: Lee MJ,Kim YC,Lew W

    更新日期:2003-04-30 00:00:00

  • Is an Isolated Weight-Holding Tremor a New Subtype of Isometric Tremor?

    abstract::A weight-holding tremor is a rare type of hand tremor that occurs only when someone holds some weight. Here we report three cases of isolated weight-holding tremors, of which one patient was diagnosed with Parkinson's disease (PD) and the others as a variant of essential tremor (ET). A 68-year-old woman presented with...

    journal_title:Yonsei medical journal

    pub_type:

    doi:10.3349/ymj.2020.61.7.644

    authors: Yong SW,Park DG,Yoon JH,Baik JS

    更新日期:2020-07-01 00:00:00

  • Comparison of natural drainage group and negative drainage groups after total thyroidectomy: prospective randomized controlled study.

    abstract:PURPOSE:The aim of this study was to compare a negative pressure drain with a natural drain in order to determine whether a negative pressure drainage tube causes an increase in the drainage volume. MATERIALS AND METHODS:Sixty-two patients who underwent total thyroidectomy for papillary thyroid carcinoma (PTC) were en...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2013.54.1.204

    authors: Woo SH,Kim JP,Park JJ,Shim HS,Lee SH,Lee HJ,Won SJ,Son HY,Kim RB,Son YI

    更新日期:2013-01-01 00:00:00

  • Two Cases of Facioscapulohumeral Muscular Dystrophy 2 in Korea.

    abstract::Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscular disorder characterized by weakness of facial, shoulder, abdominal, hip girdle, humeral, and anterior distal leg muscles, with descending progression from the face to the legs in an asymmetric pattern. In about 5% of patients with FSHD, no ...

    journal_title:Yonsei medical journal

    pub_type:

    doi:10.3349/ymj.2021.62.1.95

    authors: Lee JH,Park HJ,Seong MW,Park SS,Choi YC

    更新日期:2021-01-01 00:00:00

  • Immunohistochemical detection of p53 expression in patients with preoperative chemoradiation for rectal cancer: association with prognosis.

    abstract:PURPOSE:The expression of p53 in patients with rectal cancer who underwent preoperative chemoradiation and and its potential prognostic significance were evaluated. MATERIALS AND METHODS:p53 expression was examined using immunohistochemistry in pathologic specimens from 210 rectal cancer patients with preoperative che...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.1.82

    authors: Huh JW,Lee WY,Kim SH,Park YA,Cho YB,Yun SH,Kim HC,Park HC,Choi DH,Park JO,Park YS,Chun HK

    更新日期:2015-01-01 00:00:00

  • Epidermolysis bullosa simplex (Dowling-Meara type) associated with pyloric atresia and congenital urologic abnormalities.

    abstract::We report a case of epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM), which was associated with congenital pyloric atresia (PA) and various urologic abnormalities, a diagnosis confirmed by immunofluorescence mapping and electron microscopic findings. Immunofluorescent mapping showed the serum from a patient ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2000.41.3.411

    authors: Kim DK,Kim SC,Chang SN,Kim SY

    更新日期:2000-06-01 00:00:00

  • Neonatal outcome after preterm delivery in HELLP syndrome.

    abstract::The present study compares neonatal outcome after preterm delivery of infants in pregnancies complicated by the HELLP syndrome or severe preeclampsia (PS). The maternal and neonatal charts of 71 out of a total of 409 pregnancies that were complicated by hypertensive disorders at Severance hospital between January 1995...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.3.393

    authors: Kim HY,Sohn YS,Lim JH,Kim EH,Kwon JY,Park YW,Kim YH

    更新日期:2006-06-30 00:00:00

  • Significance of fracture gap in open tibial fracture.

    abstract::The healing pattern of medial and lateral cortical gap in open transverse or short oblique tibial fractures were retrospectively reviewed in 2 groups; In group A, 16 patients were treated by Judet external fixator in rigid mode. In group B, 6 patients were treated in biocompressive mode, which allowed predominantly lo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1995.36.2.130

    authors: Yang KH,Patel A

    更新日期:1995-05-01 00:00:00

  • Computerized optic disc analysis with adjunct stereoscopic viewing of disc photographs.

    abstract::We have investigated the potential usefulness of stereoscopic viewing of optic disc photographs in marking the disc margin in computerized analysis with the Rodenstock Analyzer in 48 eyes of 26 patients with ocular hypertension or primary open-angle glaucoma. Marking of the disc margin without Method 1) and with the a...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1990.31.4.375

    authors: Hong YJ,Shin DH

    更新日期:1990-12-01 00:00:00

  • Certain Polymorphisms in SP110 Gene Confer Susceptibility to Tuberculosis: A Comprehensive Review and Updated Meta-Analysis.

    abstract:PURPOSE:Numerous studies have assessed the association of SP110 gene variants with tuberculosis (TB), but the results were inconsistent. Through a comprehensive review and meta-analysis, our study aimed to clarify the nature of genetic risks contributed by 11 polymorphisms for the development of TB. MATERIALS AND METH...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.3349/ymj.2017.58.1.165

    authors: Zhang S,Wang XB,Han YD,Wang C,Zhou Y,Zheng F

    更新日期:2017-01-01 00:00:00

  • Localized resectable genitourinary sarcoma in adult Korean patients: experiences at a single center.

    abstract:PURPOSE:To evaluate the clinicopathological characteristics and prognosis of localized resectable genitourinary sarcomas in adults. MATERIALS AND METHODS:Between September, 1996 and November, 2008, 18 consecutive cases of adults (12 men and 6 women; median age 48.8 years) who were treated for primary genitourinary sar...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2011.52.5.761

    authors: Cho SY,Moon KC,Cheong MS,Kwak C,Kim HH,Ku JH

    更新日期:2011-09-01 00:00:00

  • Spontaneous rupture of a functioning adrenocortical carcinoma.

    abstract::Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis, and it can be classified as either a functional or nonfunctional tumor. Affected patients usually present with abdominal pain or with symptoms related to the mass effect or hormonal activity of the tumor. Several cases of spontaneously ruptured n...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.6.974

    authors: Chung JO,Cho DH,Lee JH,Kwon DD,Chung DJ,Chung MY

    更新日期:2010-11-01 00:00:00

  • Effects of adenosine tetraphosphate (ATPP) on vascular tone in the isolated rat aorta.

    abstract::Effects of a platelet-released, naturally occurring nucleotide, adenosine 5'-tetraphosphate (ATPP) on vascular tone were analyzed in the isolated rat aorta. Under resting tension ATPP (1 approximately 100 microM) elicited concentration-dependent contractions in endothelium-intact aortic rings in contrast to the concen...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1995.36.6.487

    authors: Lee JW,Kong ID,Park KS,Jeong SW

    更新日期:1995-12-01 00:00:00

  • C-Reactive Protein to Serum Albumin Ratio Is an Independent Predictor of All-Cause Mortality in Patients with ANCA-Associated Vasculitis.

    abstract:PURPOSE:We investigated whether C-reactive protein (CRP) to serum albumin ratio (CAR) could be an independent predictor of all-cause mortality in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). MATERIALS AND METHODS:We retrospectively reviewed the medical records of 170 patients w...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.7.865

    authors: Moon JS,Ahn SS,Park YB,Lee SK,Lee SW

    更新日期:2018-09-01 00:00:00

  • Granular Cell Tumors on Unusual Anatomic Locations.

    abstract::Granular cell tumors (GCTs) are soft tissue tumors, which are thought to be derived from Schwann cells. Although most GCTs are reported to arise in tongue and oral cavity (30-50%), they can appear on any anatomic sites, even visceral organs. Herein, we report 5 cases of GCTs on unusual anatomic locations, such as palm...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.6.1731

    authors: Kim HJ,Lee MG

    更新日期:2015-11-01 00:00:00

  • Renal involvement of chronic myelogenous leukemia presenting as a kidney tumor.

    abstract::Renal involvement by leukemic cells is rare in chronic myelogenous leukemia (CML). Herein, this study reports a case of CML associated with renal involvement of leukemic cells, which occurred 1 and 1/2 years after the initial diagnosis. Abdomino-pelvic computed tomography revealed a 4.4 x 4.2 cm-sized, low-density sol...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.5.944

    authors: Go JH

    更新日期:2004-10-31 00:00:00

  • Calcium uptake and release through sarcoplasmic reticulum in the inferior oblique muscles of patients with inferior oblique overaction.

    abstract::We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and controls, so as to further understand the pathogenesis of primary IOOA. Of 15 specimens ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.2.207

    authors: Kim HS,Chang YH,Kim DH,Park SR,Han SH,Lee JB

    更新日期:2006-04-30 00:00:00

  • Role of different peripheral components in the expression of neuropathic pain syndrome.

    abstract::Peripheral nerve injury frequently leads to neuropathic pain like hyperalgesia, spontaneous pain, mechanical allodynia, thermal allodynia. It is uncertain where the neuropathic pain originates and how it is transmitted to the central nervous system. This study was performed in order to determine which peripheral compo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2000.41.3.354

    authors: Won R,Lee BH,Park S,Kim SH,Park YG,Chung SS

    更新日期:2000-06-01 00:00:00

  • Intra-synovial ropivacaine and morphine for pain relief after total knee arthroplasty: a prospective, randomized, double blind study.

    abstract:PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal g...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2007.48.2.295

    authors: Han CD,Lee DH,Yang IH

    更新日期:2007-04-30 00:00:00

  • The expression of folate sensitive fragile sites in patients with bipolar disorder.

    abstract:PURPOSE:Genetic factors are known to be important in the etiology of bipolar disorder (BD). The fragile sites (FSs) are a very interesting subject for the study of clinical disorders. The aim of this study was to evaluate fragile sites seen in patients with bipolar disorder and find a correlation between some fragile s...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.1.137

    authors: Demirhan O,Tastemir D,Sertdemir Y

    更新日期:2009-02-28 00:00:00

  • The Need for New Donor Stratification to Predict Graft Survival in Deceased Donor Kidney Transplantation.

    abstract:PURPOSE:The aim of this study was to determine whether stratification of deceased donors by the United Network for Organ Sharing (UNOS) criteria negatively impacts graft survival. MATERIALS AND METHODS:We retrospectively reviewed deceased donor and recipient pretransplant variables of kidney transplantations that occu...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2017.58.3.626

    authors: Yang SS,Yang J,Ahn C,Min SI,Ha J,Kim SJ,Park JB

    更新日期:2017-05-01 00:00:00

  • A path analysis on prisoners' health behavior and medical utilization.

    abstract::In this thesis, Korean prisoners' health behavior and the characteristics of their medical utilization were surveyed and analysed. Because prisoners are inclined to be mediators of communicable diseases or unhealthy behaviors between prison institution and the outside world, health care for prisoners is directly relat...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.4.220

    authors: Sohn M,Park CY,Cho WH,Hur YJ,Yi SW

    更新日期:1997-08-01 00:00:00

  • Problems associated with alloplastic materials in rhinoplasty.

    abstract:PURPOSE:Augmentation rhinoplasty using alloplastic materials is a relatively common procedure among Asians. Silicon, expanded polytetrafluoroethylene (Gore-tex®), and porous high density polyethylene (Medpor®) are most frequently used materials. This study was conducted to analyze revisional rhinoplasty cases with allo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2014.55.6.1617

    authors: Kim HS,Park SS,Kim MH,Kim MS,Kim SK,Lee KC

    更新日期:2014-11-01 00:00:00

  • Morphological characteristics of the developing human brain during the embryonic period.

    abstract::Many features of the developing nervous system are visible from external observations of intact human embryos. In this study, a photographic atlas from the 4th to the 7th week after ovulation (Carnegie stages 10-18) is provided. The neural folds began to fuse at stage 10, and the rostral and caudal neuropore were clos...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.1.26

    authors: Yoon H,Shin YS,Lee KC,Park HW

    更新日期:1997-02-01 00:00:00

  • High dose three-dimensional conformal boost using the real-time tumor tracking radiotherapy system in cervical cancer patients unable to receive intracavitary brachytherapy.

    abstract:PURPOSE:The purpose of this study is to evaluate the clinical results of treatment with a high dose of 3-dimensional conformal boost (3DCB) using a real-time tracking radiation therapy (RTRT) system in cervical cancer patients. MATERIALS AND METHODS:Between January 2001 and December 2004, 10 patients with cervical can...

    journal_title:Yonsei medical journal

    pub_type: 临床试验,杂志文章

    doi:10.3349/ymj.2010.51.1.93

    authors: Park HC,Shimizu S,Yonesaka A,Tsuchiya K,Ebina Y,Taguchi H,Katoh N,Kinoshita R,Ishikawa M,Sakuragi N,Shirato H

    更新日期:2010-01-01 00:00:00

  • Rarity of TLR4 Asp299Gly and Thr399Ile polymorphisms in the Korean population.

    abstract:PURPOSE:Activation of the innate immune system and chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and also thought to be associated with type 2 diabetes and its complications. As a receptor for bacterial lipopolysaccharide and heat-shock proteins, Toll-like receptor 4 (...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.1.58

    authors: Kim YS,Hwang YJ,Kim SY,Yang SM,Lee KY,Park IeB

    更新日期:2008-02-29 00:00:00

  • Pharmacokinetic modeling of phagocytic activity of the liver using superparamagnetic iron oxide nanoparticles in dynamic MR imaging.

    abstract::The purpose of this study was to determine whether phagocytic activity is measurable by dynamic superparamagnetic iron oxide-enhanced MR imaging. For these experiments on New Zealand White rabbits, which were randomly allocated to normal and silica treated groups, we performed a dynamic MR study and radioisotope study...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.3.429

    authors: Na JB,Suh JS,Huh YM,Kim SJ,Kim SH,Cha SH,Lee SH

    更新日期:2003-06-30 00:00:00

  • Quantitative EMG changes during 12-week DeLorme's axiom strength training.

    abstract::Strength training is one of the most common exercises practiced in the field of physical therapy or sports training. However, limited methodology is available to evaluate its effect on the target muscle. This study aimed to test the hypothesis that surface electromyographic (EMG) data from both isometric and isotonic ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.1.93

    authors: Shin HK,Cho SH,Lee YH,Kwon OY

    更新日期:2006-02-28 00:00:00

  • Alteration of expression of Ca2+ signaling proteins and adaptation of Ca2+ signaling in SERCA2+/- mouse parotid acini.

    abstract:PURPOSE:The sarco/endoplasmic reticulum Ca2+-ATPase (SERCA), encoded by ATP2A2, is an essential component for G-protein coupled receptor (GPCR)-dependent Ca2+ signaling. However, whether the changes in Ca2+ signaling and Ca2+ signaling proteins in parotid acinar cells are affected by a partial loss of SERCA2 are not kn...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.2.311

    authors: Choi JH,Jo H,Hong JH,Lee SI,Shin DM

    更新日期:2008-04-30 00:00:00