Localized resectable genitourinary sarcoma in adult Korean patients: experiences at a single center.

Abstract:

PURPOSE:To evaluate the clinicopathological characteristics and prognosis of localized resectable genitourinary sarcomas in adults. MATERIALS AND METHODS:Between September, 1996 and November, 2008, 18 consecutive cases of adults (12 men and 6 women; median age 48.8 years) who were treated for primary genitourinary sarcomas were identified. The following variables were analyzed: patient age, gender, body mass index, American Society of Anesthesiologists (ASA) score, primary organ, tumor histology, size, necrosis, Fédération Nationale des Centres de Lutte Contre le Cancer (FNCLCC) grade, and surgical margin positivity. Recurrence- free survival and disease-specific survival were the study end-points. RESULTS:The most common presenting symptom was a palpable mass (six cases, 33.3%), the most common site was the kidney (six cases, 33.3%), and the most common histological subtype was leiomyosarcoma (eight patients, 44.4%). Complete resection with negative surgical margins was achieved in 13 patients (72.2%). The median follow-up period was 49.9 months (range 6.4 to 147.6). The recurrence- free survival rates at 1, 3, and 5 years were 81.6%, 66.5%, and 66.5%, respectively. Recurrence-free survival only associated significantly with ASA score (p=0.018). The disease-specific survival rate at 1, 3, and 5 years was 88.9%, 76.2%, and 67.7%, respectively. Disease-specific survival was associated significantly only with FNCLCC grade (p=0.042). CONCLUSION:Although genitourinary sarcomas in adults are a rare group of tumors with a poor prognosis, some patients may have a favorable prognosis. Our findings suggest that FNCLCC grade is the most important prognostic factor for these patients.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Cho SY,Moon KC,Cheong MS,Kwak C,Kim HH,Ku JH

doi

10.3349/ymj.2011.52.5.761

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

761-7

issue

5

eissn

0513-5796

issn

1976-2437

pii

201109761

journal_volume

52

pub_type

杂志文章
  • Revolution and refinement of surgical techniques for living donor partial liver transplantation.

    abstract::Living donor liver transplantation (LDLT) was first successfully performed on a child in 1990 and the Shinshu group performed the same procedure on an adult for the first time in 1994. Over the past few years adult LDLT has been increasing worldwide because of the severe shortage of cadaveric organs, especially in loc...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2004.45.6.1076

    authors: Dulundu E,Sugawara Y,Makuuchi M

    更新日期:2004-12-31 00:00:00

  • Kinematically Aligned Total Knee Arthroplasty with Patient-Specific Instrument.

    abstract::Kinematically aligned total knee arthroplasty (TKA) is a new alignment technique. Kinematic alignment corrects arthritic deformity to the patient's constitutional alignment in order to position the femoral and tibial components, as well as to restore the knee's natural tibial-femoral articular surface, alignment, and ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2020.61.3.201

    authors: Kim KK,Howell SM,Won YY

    更新日期:2020-03-01 00:00:00

  • Protective effect of ultra low molecular weight heparin on glutamate-induced apoptosis in cortical cells.

    abstract:PURPOSE:To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS:Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptosis was first an...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.3.486

    authors: Yu TG,Zhang QZ,Zhang ZG,Wang WW,Ji SL,Du GH

    更新日期:2008-06-30 00:00:00

  • Neurologic recovery according to the spinal fracture patterns by Denis classification.

    abstract:PURPOSE:Although Denis classification is considered as one of most clinically useful schemes for the evaluation of spinal fracture, there is little documentation on the relationship between fracture pattern and the neurologic recovery. The purpose is to evaluate the correlation between the fracture patterns according t...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.3.715

    authors: Park MS,Moon SH,Yang JH,Lee HM

    更新日期:2013-05-01 00:00:00

  • Real-time determination of left ventricular ejection fraction by automatic boundary detection in patients with dilated cardiomyopathy: a comparison with radionuclide ventriculography.

    abstract::Echocardiographic automatic boundary detection (ABD) is a new on-line technique which automatically outlines the left ventricular endocardial border and instantly calculates the left ventricular area and volume from two dimensional echocardiographic images. To determine if left ventricular ejection fraction (LVEF) can...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1996.37.6.385

    authors: Ha JW,Chung N,Choe KH,Kwan J,Rim SJ,Jang Y,Kim JY,Oh EK,Lee YJ,Shim WH,Cho SY,Kim SS

    更新日期:1996-12-01 00:00:00

  • No evidence of an association between A218C polymorphism of the tryptophan hydroxylase 1 gene and aggression in schizophrenia in a Korean population.

    abstract:PURPOSE:We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. MATERIALS AND METHODS:The sample included 61 aggressive patients as well as 104 non-aggressive patients from psychiatric hospitals and 335 healthy volunteers in Korea. Blood s...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.1.27

    authors: Kim YR,Lee JY,Min SK

    更新日期:2010-01-01 00:00:00

  • Comparison of Outcomes after Device Closure and Medication Alone in Patients with Patent Foramen Ovale and Cryptogenic Stroke in Korean Population.

    abstract:PURPOSE:To compare the effectiveness of device closure and medical therapy in prevention of recurrent embolic event in the Korean population with cryptogenic stroke and patent foramen ovale (PFO). MATERIALS AND METHODS:Consecutive 164 patients (men: 126 patients, mean age: 48.1 years, closure group: 72 patients, medic...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.3.621

    authors: Moon J,Kang WC,Kim S,Oh PC,Park YM,Chung WJ,Choi DY,Lee JY,Lee YB,Hwang HY,Ahn T

    更新日期:2016-05-01 00:00:00

  • Compliance and effective management of the hand-foot syndrome in colon cancer patients receiving capecitabine as adjuvant chemotherapy.

    abstract:PURPOSE:Physicians and oncology nurses must continue to update their knowledge on treatment and treatment-related side effects, while searching for effective methods to prevent or manage side effects. The objective of our study was to describe the incidence and response to treatment of the hand-foot syndrome (HFS) and ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.6.796

    authors: Son HS,Lee WY,Lee WS,Yun SH,Chun HK

    更新日期:2009-12-31 00:00:00

  • Intra-synovial ropivacaine and morphine for pain relief after total knee arthroplasty: a prospective, randomized, double blind study.

    abstract:PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal g...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2007.48.2.295

    authors: Han CD,Lee DH,Yang IH

    更新日期:2007-04-30 00:00:00

  • Endoscopic laser surgery for subglottic stenosis in Wegener's granulomatosis.

    abstract:PURPOSE:Wegener's granulomatosis (WG) is a rare multisystem inflammatory disease, which infrequently involves the subglottic area and trachea. Treatment usually involves the use of immunosuppressive agents with corticosteroids. Some patients, however, continue to have symptoms of airway obstruction after clinical remis...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.5.748

    authors: Shvero J,Shitrit D,Koren R,Shalomi D,Kramer MR

    更新日期:2007-10-31 00:00:00

  • Association of CYP2C19*2 and *3 genetic variants with essential hypertension in Koreans.

    abstract:PURPOSE:The cytochrome P450 2C19 (CYP2C19) metabolizes arachidonic acid to produce epoxyicosanoid acids, which are involved in vascular tone and regulation of blood pressure. Recent findings suggest that CYP2C19 gene might be considered as a novel candidate gene for treatment of cardiovascular disease. The aim of the p...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.6.1113

    authors: Shin DJ,Kwon J,Park AR,Bae Y,Shin ES,Park S,Jang Y

    更新日期:2012-11-01 00:00:00

  • A case of acute ventricular capture threshold rise associated with flecainide acetate.

    abstract::Antiarrhythmic agents may increase capture threshold, but this is rarely of clinical significance. Flecainide acetate, a class IC agent, is reported to have a significant effect on the myocardial capture threshold. In this presentation, we report the case of a 72-year-old male, with a previously implanted VVI pacemake...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.1.152

    authors: Kang TS,Yoon YW,Park S,Hong BK,Kim D,Kwon HM,Kim HS

    更新日期:2006-02-28 00:00:00

  • Angiotensinogen and angiotensin II type 1 receptor gene polymorphism in patients with autosomal dominant polycystic kidney disease: effect on hypertension and ESRD.

    abstract::Autosomal dominant polycystic kidney disease (ADPKD), a common genetic disease, is characterized by the development of hypertension and end stage renal disease. An increase in the activity of the renin-angiotensin system, due to a renal ischemia caused by cyst expansion, contributes to the development of hypertension ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.4.641

    authors: Lee KB,Kim UK

    更新日期:2003-08-30 00:00:00

  • Impact of Insulin Resistance on Acetylcholine-Induced Coronary Artery Spasm in Non-Diabetic Patients.

    abstract:PURPOSE:Coronary artery spasm (CAS) and diabetes mellitus (DM) are implicated in endothelial dysfunction, and insulin resistance (IR) is a major etiological cause of type 2 DM. However, the association between CAS and IR in non-diabetic individuals has not been elucidated. The aim of the present study was to evaluate t...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.9.1057

    authors: Kang KW,Choi BG,Rha SW

    更新日期:2018-11-01 00:00:00

  • Complement-fixing abilities and IgG subclasses of autoantibodies in epidermolysis bullosa acquisita.

    abstract::Epidermolysis bullosa acquisita (EBA) is an autoimmune-mediated subepidermal bullous disease in which the target of the autoantibodies is type VII collagen, a major component of anchoring fibrils. The purpose of this study was to evaluate the complement-fixing abilities and IgG subclass distribution of autoantibodies ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1998.39.4.339

    authors: Cho HJ,Lee IJ,Kim SC

    更新日期:1998-08-01 00:00:00

  • Anaplastic thyroid carcinoma: a therapeutic dilemma.

    abstract::Anaplastic thyroid carcinoma (ATC) is one of the most malignant human neoplasms and has a grave prognosis. This study gives an update on our experience with this unusual neoplasm, with specific focus on the response to various treatment modalities. Forty-seven patients with histologically proven ATCs were enrolled (19...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.6.759

    authors: Chang HS,Nam KH,Chung WY,Park CS

    更新日期:2005-12-31 00:00:00

  • Circulating immune complexes and cell-mediated immunity in patients with hepatitis B virus associated liver diseases.

    abstract::The prevalence of circulating immune complexes (CIC), their role and their relationship to cell-mediated immunity in patients with hepatitis B virus associated liver disease are still controversial. This study was designed to investigate the prevalence of CIC and their relationship to viral markers, to subsets of peri...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1990.31.4.347

    authors: Kim SA,Lee SI,Choi IH,Shin JS,Uhm JR,Kim SJ,Choi HJ

    更新日期:1990-12-01 00:00:00

  • Retraction: Paper "Comparison of Effect of Treatment with Etidronate and Alendronate on Lumbar Bone Mineral Density in Elderly Women with Osteoporosis" by Iwamoto J, et al. [Yonsei Med J 2005;46(6):750-758].

    abstract::This corrects the article on p. 750 in vol. 46, PMID: 16385649. ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,撤回出版物

    doi:10.3349/ymj.2019.60.1.117

    authors:

    更新日期:2019-01-01 00:00:00

  • Retrospective assessment of the validity of robotic surgery in comparison to open surgery for pediatric choledochal cyst.

    abstract:PURPOSE:We evaluated the validity of robotic surgery (RS) for pediatric choledochal cyst (CC) in comparison to open surgery (OS). MATERIALS AND METHODS:From January 2009 to April 2013, clinical data from 79 consecutive pediatric patients with CC, who underwent RS (n=36) or OS (n=43) performed by a single pediatric sur...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.3.737

    authors: Kim NY,Chang EY,Hong YJ,Park S,Kim HY,Bai SJ,Han SJ

    更新日期:2015-05-01 00:00:00

  • Bacteriologic characteristics and serotypings of Streptococcus pyogenes isolated from throats of school children.

    abstract::To determine the carrier rate of beta-hemolytic streptococci (BHS), throat cultures were taken from healthy elementary school children in four separate areas of Korea from 1992 to 1995, including Inje, Nonsan, Seoul and Chinju. The strains of Streptococcus pyogenes had been serotyped with anti-T, -OF and -M sera. The ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2000.41.1.56

    authors: Kim SJ

    更新日期:2000-02-01 00:00:00

  • Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease.

    abstract:PURPOSE:The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous immunoglobulin (IVIG). PATIENTS AND METHODS:The patients who had persistent or recrudescent fever after treatment with IVIG were subse...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.5.714

    authors: Lee TJ,Kim KH,Chun JK,Kim DS

    更新日期:2008-10-31 00:00:00

  • Diagnostic value of insulin-like growth factor-I in short stature.

    abstract::For the present, to determine growth hormone(GH) deficiency in patients with short stature, many provocative tests using various pharmacological agents such as glucagon, insulin, clonidine, arginine, growth hormone releasing factor, etc. should be done. These are not only complicated but are also misleading in some pa...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1989.30.4.367

    authors: Park MS,Kim DH

    更新日期:1989-12-01 00:00:00

  • Mismatch between TOF MR Angiography and CT Angiography of the Middle Cerebral Artery may be a Critical Sign in Cerebrovascular Dynamics.

    abstract:PURPOSE:Although time-of-flight (TOF)-magnetic resonance angiography (MRA) can clearly depict intracranial arteries, the arterial flow of middle cerebral artery (MCA) is occasionally not detected. We evaluated this phenomenon with reference to cerebrovascular dynamics. MATERIALS AND METHODS:Seventeen patients with sus...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.1.80

    authors: Igase K,Igase M,Matsubara I,Sadamoto K

    更新日期:2018-01-01 00:00:00

  • Effect of excitability-inducing material on regenerative Ca++ release of rat ventricular muscle.

    abstract::The effects of excitability-inducing materials (EIM) and electrical stimulation on Ca+(+)-induced Ca++ release were studied in this experiment. Direct application of three EIM (bacterial EIM, alamethicin, Nal) did not release Ca++ from skinned rat cardiac fibers or from an SR suspension. Direct electrical stimulation ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1991.32.3.215

    authors: Kang DH,Lee YH,Song HJ

    更新日期:1991-09-01 00:00:00

  • Associations of moderate to severe asthma with obstructive sleep apnea.

    abstract:PURPOSE:This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA). MATERIALS AND METHODS:One hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered brea...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.4.942

    authors: Byun MK,Park SC,Chang YS,Kim YS,Kim SK,Kim HJ,Chang J,Ahn CM,Park MS

    更新日期:2013-07-01 00:00:00

  • Antimicrobial susceptibility of Campylobacter fetus subsp. fetus isolated from blood and synovial fluid.

    abstract::Campylobacter fetus subsp. fetus is a rare human pathogen, but can cause serious extraintestinal infections. Effective antimicrobial agent is required for the therapy, but we have very limited knowledge on the susceptibility of the organism. In this study, the susceptibility of 25 isolates of the organism to 14 antimi...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1994.35.3.314

    authors: Kwon SY,Cho DH,Lee SY,Lee K,Chong Y

    更新日期:1994-09-01 00:00:00

  • Subdiaphragmatic vagotomy induces NADPH diaphorase in the rat dorsal motor nucleus of the vagus.

    abstract::Axotomy of the vagal motor neurons by cervical vagotomy induces NADPH diaphorase staining due to increased nitric oxide synthase expression in both the rat dorsal motor nucleus and nucleus ambiguous; furthermore, cerical vagotomy leads to cell death of the dorsal motor nucleus cells. Subdiaphragmatic vagotomy axotomiz...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2001.42.2.215

    authors: Jahng JW,Kim DG,Houpt TA

    更新日期:2001-04-01 00:00:00

  • The expression of estrogen receptors in hepatocellular carcinoma in Korean patients.

    abstract::Expression of estrogen receptors (ER)-alpha and -beta, as well as androgen receptor (AR), in hepatocellular carcinoma (HCC) is thought to be correlated with prognosis, survival, and male prevalence of HCC. These hypotheses are based on investigations of European patients; however the expression patterns of these recep...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.6.811

    authors: Wang AG,Lee KY,Kim SY,Choi JY,Lee KH,Kim WH,Wang HJ,Kim JM,Park MG,Yeom YI,Kim NS,Yu DY,Lee DS

    更新日期:2006-12-31 00:00:00

  • Low Expression of Circulating MicroRNA-34c is Associated with Poor Prognosis in Triple-Negative Breast Cancer.

    abstract:PURPOSE:The microRNA-34 (miR-34) family is important in tumor regulation. This study aimed to investigate the association of circulating miR-34 family proteins with clinicopathological features and their prognostic value in triple-negative breast cancer (TNBC) patients. MATERIALS AND METHODS:In this cohort study, 173 ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2017.58.4.697

    authors: Zeng Z,Chen X,Zhu D,Luo Z,Yang M

    更新日期:2017-07-01 00:00:00

  • Prostate cancer with solitary metastases to the bilateral testis.

    abstract::We present the case of an 81-year-old patient with testicular metastasis from prostate carcinoma. After the initial diagnosis of prostate cancer, he had an 8-year course of hormonal therapy and showed no clinical evidence of metastasis to other organs. Asymptomatic metastasis of prostate carcinoma to the testis is a r...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2011.52.2.362

    authors: Kim SO,Choi YD,Jung SI,Oh KJ,Im CM,Kang TW,Kwon D,Park K,Ryu SB

    更新日期:2011-03-01 00:00:00