Renal involvement of chronic myelogenous leukemia presenting as a kidney tumor.

Abstract:

:Renal involvement by leukemic cells is rare in chronic myelogenous leukemia (CML). Herein, this study reports a case of CML associated with renal involvement of leukemic cells, which occurred 1 and 1/2 years after the initial diagnosis. Abdomino-pelvic computed tomography revealed a 4.4 x 4.2 cm-sized, low-density solid mass having a thick wall from the mid to lower pole of the left kidney. A peripheral blood analysis revealed blastic transformation of CML. The biopsied renal parenchyme was diffusely infiltrated by sheets of immature myeloid cells, polymorphonuclear leukocytes, and occasional eosinophils. Most of the infiltrating cells were positive for anti-neutrophil elastase, but negative for lymphoid markers. Therefore, differential diagnosis of a kidney tumor during the course of CML, especially in the time of blastic transformation, should be performed.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Go JH

doi

10.3349/ymj.2004.45.5.944

keywords:

subject

Has Abstract

pub_date

2004-10-31 00:00:00

pages

944-6

issue

5

eissn

0513-5796

issn

1976-2437

pii

200410944

journal_volume

45

pub_type

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