Effects of chronic aluminum administration on blood and liver iron-related parameters in mice.

Abstract:

:In this study, the effects of chronically administered aluminum on iron metabolism-related parameters of liver and blood of mice were investigated. An additional purpose to determine how chronic aluminum administration together with vitamin E as an antioxidant to mice changed the parameters related to iron metabolism. For these purposes, we used 21 adult female Balb-c mice in this study. The animals were divided into three groups: one group with aluminum administered chronically, another group with aluminum plus vitamin E administered chronically, and the control group. Serum levels of hemoglobin, ferritin, iron, transferrin, hematocrit, total iron binding capacity (TIBC), as well as percentage of transferrin saturation were determined in all groups. In addition, the liver tissue levels of ferritin and iron were analyzed. Hemoglobin and hematocrit levels of the aluminum group and aluminum plus vitamin E group were significantly decreased compared to the control. In conclusion, no changes occurred in the serum iron related parameters although Al induced anemia in mice when Al administered chronically. There was an increase in the levels of liver iron and ferritin with Al, but Vit E had no effect on the changes of all blood and liver parameters caused by Al.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Turgut G,Kaptanoğlu B,Turgut S,Enli Y,Genç O

doi

10.3349/ymj.2004.45.1.135

keywords:

subject

Has Abstract

pub_date

2004-02-29 00:00:00

pages

135-9

issue

1

eissn

0513-5796

issn

1976-2437

pii

200402135

journal_volume

45

pub_type

杂志文章
  • Spontaneous rupture of a functioning adrenocortical carcinoma.

    abstract::Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis, and it can be classified as either a functional or nonfunctional tumor. Affected patients usually present with abdominal pain or with symptoms related to the mass effect or hormonal activity of the tumor. Several cases of spontaneously ruptured n...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.6.974

    authors: Chung JO,Cho DH,Lee JH,Kwon DD,Chung DJ,Chung MY

    更新日期:2010-11-01 00:00:00

  • The role of estrogen receptor, progesterone receptor and p53 in development of stress urinary incontinence.

    abstract::Recent studies have been reported the roles of the estrogen receptor (ER), progesterone receptor (PR) and p53 in the development of a pelvic organ prolapse (POP). The pathogenesis of stress urinary incontinence (SUI) is related to that of POP in the weakness of pelvic support. Therefore, this study was carried out to ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.5.885

    authors: Bai SW,Jung YW,Kwon HS,Yoon JM,Shin JS,Kim SK,Park KH,Park JH

    更新日期:2004-10-31 00:00:00

  • A clinicopathological study of Kimura's disease and epithelioid hemangioma.

    abstract::The clinicopathological features of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma(EH) were reviewed. Patients with Kimura's disease presented with multiple or solitary large tumors occurring in the thigh, arms as well as parotid gland. Histologically, the lesions were characterized by numerous lymp...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1990.31.3.205

    authors: Ahn HJ,Lee KG

    更新日期:1990-09-01 00:00:00

  • Gordius worm found in a three year old girl's vomitus.

    abstract::Since the Gordius worm is a parasite of crickets and several arthropods, cases of humans infected with this worm have been rare and accidental. A Gordius worm was obtained from a three-year-old girl who consulted a local clinic in Gwangju, Kyunggi-do, Korea. She lived in a rural area, and had eaten an insect that look...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2003.44.3.557

    authors: Lee KJ,Bae YT,Kim DH,Deung YK,Ryang YS,Im KI,Yong TS

    更新日期:2003-06-30 00:00:00

  • In vitro antifungal activity of epigallocatechin 3-O-gallate against clinical isolates of dermatophytes.

    abstract::Previously, we reported that epigallocatechin 3-O-gallate (EGCg) has growth-inhibitory effect on clinical isolates of Candida species. In this study, we investigated the antifungal activity of EGCg and antifungal agents against thirty-five of dermatophytes clinically isolated by the international guidelines (M38-A2). ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2011.52.3.535

    authors: Park BJ,Taguchi H,Kamei K,Matsuzawa T,Hyon SH,Park JC

    更新日期:2011-05-01 00:00:00

  • The effects of wild type p53 tumor suppressor gene expression on the normal human cervical epithelial cells or human epidermal keratinocytes transformed with human papillomavirus type 16 DNA.

    abstract::The inactivation of p53 and p105RB by viral proteins or by mutations plays a key role in the oncogenesis of cervical carcinoma. The E6 and E7 proteins of HPV type 16 can bind to p53 and p105RB tumor suppressor gene products, respectively. In the present study, we tested a simple in vivo model that could explain the in...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1995.36.3.287

    authors: Kim KH,Park TK,Yoon DJ,Kim YS

    更新日期:1995-07-01 00:00:00

  • Posterior lumbar interbody fusion via a unilateral approach.

    abstract::This study sought to determine the outcomes of posterior lumbar interbody fusion (PLIF), via a unilateral approach, in selected patients who presented with unilateral leg pain and segmental instability of the lumbar spine. Patients with a single level of a herniated disc disease in the lumbar spine, unilateral leg pai...

    journal_title:Yonsei medical journal

    pub_type: 临床试验,杂志文章

    doi:10.3349/ymj.2006.47.3.319

    authors: Shin HC,Yi S,Kim KN,Kim SH,Yoon DH

    更新日期:2006-06-30 00:00:00

  • Pharmacokinetic modeling of phagocytic activity of the liver using superparamagnetic iron oxide nanoparticles in dynamic MR imaging.

    abstract::The purpose of this study was to determine whether phagocytic activity is measurable by dynamic superparamagnetic iron oxide-enhanced MR imaging. For these experiments on New Zealand White rabbits, which were randomly allocated to normal and silica treated groups, we performed a dynamic MR study and radioisotope study...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.3.429

    authors: Na JB,Suh JS,Huh YM,Kim SJ,Kim SH,Cha SH,Lee SH

    更新日期:2003-06-30 00:00:00

  • Extracting extra-telomeric phenotypes from telomerase mouse models.

    abstract::Telomerase reverse transcriptase (TERT) is the protein component of telomerase and combined with an RNA molecule, telomerase RNA component, forms the telomerase enzyme responsible for telomere elongation. Telomerase is essential for maintaining telomere length from replicative attrition and thus contributes to the pre...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2014.55.1.1

    authors: Sung YH,Ali M,Lee HW

    更新日期:2014-01-01 00:00:00

  • Operative laparoscopy in treating benign ovarian cysts.

    abstract::This study was undertaken to evaluate the clinical usefulness of operative laparoscopy in treatment of benign ovarian cysts. A retrospective study was carried on 468 operative laparoscopy cases performed from September 1995 to September 1998 at Yonsei University College of Medicine, Department of Obstetrics and Gyneco...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1999.40.6.608

    authors: Park KH,Chung JE,Kim JY,Lee BS

    更新日期:1999-12-01 00:00:00

  • Application of ultrasound-guided trigger point injection for myofascial trigger points in the subscapularis and pectoralis muscles to post-mastectomy patients: a pilot study.

    abstract:PURPOSE:To investigate the therapeutic effectiveness of ultrasound (US)-guided trigger point injection for myofascial trigger points (MTrPs) in the internal rotator muscles of the shoulder in post-mastectomy patients. MATERIALS AND METHODS:This pilot study was a non-controlled, prospective, clinical trial. Nineteen po...

    journal_title:Yonsei medical journal

    pub_type: 临床试验,杂志文章

    doi:10.3349/ymj.2014.55.3.792

    authors: Shin HJ,Shin JC,Kim WS,Chang WH,Lee SC

    更新日期:2014-05-01 00:00:00

  • Eleven-year experience of low grade lymphoma in Korea (based on REAL classification).

    abstract::Low grade lymphomas are malignancies of predominantly small lymphocytes that typically have long median survival periods due to low proliferative rates. It is considered an indolent disease, but patients with low grade lymphoma can almost never be cured with conventional treatment. New low- grade lymphoma entities hav...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.5.757

    authors: Hahn JS,Kim YS,Lee YC,Yang WI,Lee SY,Suh CO

    更新日期:2003-10-30 00:00:00

  • Effects of epithelium on the mechanism of mediator release from guinea pig tracheal tissues sensitized by IgG1 versus IgE antibody.

    abstract::In the present work, we have examined the effect of PAF, removal of epithelium, the mechanism of desensitization, and the substances that increases the level of intracellular c-AMP on the differences of mediator release from superfused tracheal strips after passive sensitization with IgG1 versus IgE Ab. In the passive...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1995.36.2.161

    authors: Ro JY,Kim KH

    更新日期:1995-05-01 00:00:00

  • Relationships between serum adiponectin with metabolic syndrome and components of metabolic syndrome in non-diabetic Koreans: ARIRANG study.

    abstract:PURPOSE:Growing evidence suggests that hypoadiponectinemia may play a significant role in the development of metabolic syndrome (MetS). Therefore, the relationships between serum adiponectin with MetS and components of MetS were investigated in non-diabetic samples of drawn from the Koreans general population. MATERIA...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2011.52.2.234

    authors: Koh SB,Yoon J,Kim JY,Yoo BS,Lee SH,Park JK,Choe KH

    更新日期:2011-03-01 00:00:00

  • Robotic colorectal surgery.

    abstract::Robotic colorectal surgery has gradually been performed more with the help of the technological advantages of the da Vinci system. Advanced technological advantages of the da Vinci system compared with standard laparoscopic colorectal surgery have been reported. These are a stable camera platform, three-dimensional im...

    journal_title:Yonsei medical journal

    pub_type: 历史文章,杂志文章,评审

    doi:10.3349/ymj.2008.49.6.891

    authors: Baik SH

    更新日期:2008-12-31 00:00:00

  • Variants of Lipolysis-Related Genes in Korean Patients with Very High Triglycerides.

    abstract::We investigated the prevalence and characteristics of variants of five lipolysis-related genes in Korean patients with very high triglycerides (TGs). Twenty-six patients with TG levels >885 mg/dL were selected from 13545 Korean subjects. Five candidate genes, LPL, APOC2, GPIHBP1, APOA5, and LMF1, were sequenced by tar...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.1.148

    authors: Lee CJ,Oum CY,Lee Y,Park S,Kang SM,Choi D,Jang Y,Lee JH,Lee SH

    更新日期:2018-01-01 00:00:00

  • Nonspecific interstitial pneumonitis after bortezomib and thalidomide treatment in a multiple myeloma patient.

    abstract::Bortezomib, an inhibitor of 26S proteosome, is recently approved treatment option for multiple myeloma. Thalidomide, a drug with immunomodulating and antiangiogenic effects, has also shown promise as an effective treatment in multiple myeloma. Pulmonary complications are believed to be rare, especially interstitial lu...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.3.448

    authors: Kang W,Kim JS,Cho SH,Kim SK,Chang J,Park MS

    更新日期:2010-05-01 00:00:00

  • Current management and future strategies of gastric cancer.

    abstract::The overall prognosis of gastric cancer has gradually improved over the past decades with growing awareness of potential carcinogens, surveillance programs and early diagnosis, as well as advances in surgical techniques and multimodality treatments. Nevertheless, the outcome of advanced stage disease still remains poo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2012.53.2.248

    authors: Lee JH,Kim KM,Cheong JH,Noh SH

    更新日期:2012-03-01 00:00:00

  • MicroRNA-98-5p Inhibits Tumorigenesis of Hepatitis B Virus-Related Hepatocellular Carcinoma by Targeting NF-κB-Inducing Kinase.

    abstract:PURPOSE:MicroRNAs play key regulatory roles in the tumorigenesis of hepatitis B virus-related hepatocellular carcinoma (HBV-HCC). This study aimed to explore the regulatory effects of microRNA-98-5p (miR-98-5p) on the proliferation, migration, invasion, and apoptosis of HBV-HCC cells, as well as the underlying mechanis...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2020.61.6.460

    authors: Fei X,Zhang P,Pan Y,Liu Y

    更新日期:2020-06-01 00:00:00

  • Protective effect of ultra low molecular weight heparin on glutamate-induced apoptosis in cortical cells.

    abstract:PURPOSE:To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS:Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptosis was first an...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.3.486

    authors: Yu TG,Zhang QZ,Zhang ZG,Wang WW,Ji SL,Du GH

    更新日期:2008-06-30 00:00:00

  • A path analysis on prisoners' health behavior and medical utilization.

    abstract::In this thesis, Korean prisoners' health behavior and the characteristics of their medical utilization were surveyed and analysed. Because prisoners are inclined to be mediators of communicable diseases or unhealthy behaviors between prison institution and the outside world, health care for prisoners is directly relat...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.4.220

    authors: Sohn M,Park CY,Cho WH,Hur YJ,Yi SW

    更新日期:1997-08-01 00:00:00

  • Effects of Coronary Artery Revascularization with a Polymer-Free Biolimus A9-Coated BioFreedom Stent Versus Bypass Surgery before Noncardiac Surgery.

    abstract:PURPOSE:The present study aimed to evaluate the efficacy and safety of polymer-free drug-coated BioFreedom stent implantation in comparison to coronary artery bypass graft (CABG) before major noncardiac surgery. MATERIALS AND METHODS:In a multicenter registry, 55 patients required revascularization before major noncar...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.4.480

    authors: Kim K,Kim C,Kim BK,Jang JY,Her AY,Kim S,Hong SJ,Ahn CM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y

    更新日期:2018-06-01 00:00:00

  • Ultra-early surgery for poor-grade intracranial aneurysmal subarachnoid hemorrhage: a preliminary study.

    abstract:PURPOSE:To describe the therapeutic effect and possibility of the ultra-early surgery for poor-grade aneurysmal subarachnoid hemorrhage (Hunt-Hess grades IV-V). MATERIALS AND METHODS:Nine cases with intracranial aneurysms, demonstrated by computed tomographic angiography (CTA), were treated by ultra-early surgery unde...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.4.521

    authors: Pan JW,Zhan RY,Wen L,Tong Y,Wan S,Zhou YY

    更新日期:2009-08-31 00:00:00

  • Coronary Stent Infection Presented as Recurrent Stent Thrombosis.

    abstract::Percutaneous transluminal coronary angioplasty with metal stent placement has become a well-developed treatment modality for coronary stenotic lesions. Although infection involving implanted stents is rare, it can, however, occur with high morbidity and mortality. We describe herein a case of an inserted coronary sten...

    journal_title:Yonsei medical journal

    pub_type:

    doi:10.3349/ymj.2017.58.2.458

    authors: Lai CH,Lin YK,Lee WL,Chang WC

    更新日期:2017-03-01 00:00:00

  • Production of egg yolk antibodies specific to house dust mite proteins.

    abstract:PURPOSE:House dust mites (HDMs) are an important source of indoor allergens associated with asthma, rhinitis and atopic dermatitis. Chicken immunoglobulin (Ig) Y is known to be a good alternative to mice and rabbit antibody production. In this study, we produced IgYs specific to HDMs and investigated their IgE immunore...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2014.55.4.999

    authors: Lee KE,Han BK,Han JY,Hong JY,Kim MN,Heo WI,Sohn MH,Kim KW,Kim KE

    更新日期:2014-07-01 00:00:00

  • Preoperative Lymphocyte-Monocyte Ratio Ameliorates the Accuracy of Differential Diagnosis in Non-Metastatic Infiltrative Renal Masses.

    abstract:PURPOSE:Distinguishing infiltrative renal cell carcinoma (RCC) from transitional cell carcinoma (TCC) is a challenging issue due to their radiologic similarities. We evaluated systemic inflammatory biomarkers as parameters for distinguishing tumor types. MATERIALS AND METHODS:A computerized search of medical records f...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2017.58.2.388

    authors: Han JH,Yoon YE,Kim SY,Cho YI,Rha KH,Choi YD,Han WK

    更新日期:2017-03-01 00:00:00

  • Lateralization of cognitive functions in aphasia after right brain damage.

    abstract:PURPOSE:The lateralization of cognitive functions in crossed aphasia in dextrals (CAD) has been explored and compared mainly with cases of aphasia with left hemisphere damage. However, comparing the neuropsychological aspects of CAD and aphasia after right brain damage in left-handers (ARL) could potentially provide mo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.3.486

    authors: Ha JW,Pyun SB,Hwang YM,Sim H

    更新日期:2012-05-01 00:00:00

  • Aldehyde Dehydrogenase 2 (ALDH2) Polymorphism and the Risk of Alcoholic Liver Cirrhosis among East Asians: A Meta-Analysis.

    abstract:PURPOSE:The aldehyde dehydrogenase 2 (ALDH2) gene has been implicated in the development of alcoholic liver cirrhosis (ALC) in East Asians. However, the results are inconsistent. In this study, a meta-analysis was performed to assess the associations between the ALDH2 polymorphism and the risk of ALC. MATERIALS AND ME...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,meta分析

    doi:10.3349/ymj.2016.57.4.879

    authors: He L,Deng T,Luo H

    更新日期:2016-07-01 00:00:00

  • Initial experiences with proton MR spectroscopy in treatment monitoring of mitochondrial encephalopathy.

    abstract:PURPOSE:Mitochondrial encephalopathy (ME) is a rare disorder of energy metabolism. The disease course can roughly be evaluated by clinical findings. The purpose of this study was to evaluate metabolic spectral changes using proton MR spectroscopy (MRS), and to establish a way to monitor ME by neuroimaging. MATERIALS A...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.5.672

    authors: Lee SK,Kim J,Kim HD,Lee JS,Lee YM

    更新日期:2010-09-01 00:00:00

  • Cloning and expression of rat liver type glucose transporter and translocation by insulin in Chinese hamster ovary cells.

    abstract::The 5'- and 3'-side half of liver type glucose transporter (GLUT2) cDNA was amplified from total RNA or mRNA by reverse transcriptase-polymerase chain reaction (RT-PCR). The amplified 5'-side fragment of GLUT2 cDNA was inserted into pGEM4Z and named pGLGT1, and the 3'-side fragment of GLUT2 cDNA was inserted into the ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1993.34.2.117

    authors: Ahn YH,Yoon DJ,Han GS,Lee BG

    更新日期:1993-06-01 00:00:00