In vitro antifungal activity of epigallocatechin 3-O-gallate against clinical isolates of dermatophytes.

Abstract:

:Previously, we reported that epigallocatechin 3-O-gallate (EGCg) has growth-inhibitory effect on clinical isolates of Candida species. In this study, we investigated the antifungal activity of EGCg and antifungal agents against thirty-five of dermatophytes clinically isolated by the international guidelines (M38-A2). All isolates exhibited good susceptibility to EGCg (MIC₅₀, 2-4 μg/mL, MIC₉₀, 4-8 μg/mL, and geometric mean (GM) MICs, 3.36-4 μg/mL) than those of fluconazole (MIC₅₀, 2-16 μg/mL, MIC₉₀, 4-32 μg/mL, and GM MICs, 3.45-25.8 μg/mL) and flucytosin (MIC₅₀, MIC₉₀, and GM MICs, >64 μg/mL), although they were less susceptible to other antifungal agents, such as amphotericin B, itraconazole, and miconazole. These activities of EGCg were approximately 4-fold higher than those of fluconazole, and were 4 to 16-fold higher than flucytosin. This result indicates that EGCg can inhibit pathogenic dermatophyte species. Therefore, we suggest that EGCg may be effectively used solely as a possible agent or combined with other antifungal agents for antifungal therapy in dermatophytosis.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Park BJ,Taguchi H,Kamei K,Matsuzawa T,Hyon SH,Park JC

doi

10.3349/ymj.2011.52.3.535

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

535-8

issue

3

eissn

0513-5796

issn

1976-2437

pii

201105535

journal_volume

52

pub_type

杂志文章
  • A case of primary bilateral adrenal lymphoma (PAL) with central nervous system (CNS) involvement.

    abstract::Primary adrenal lymphoma (PAL) is a very rare disease and usually does not have disease elsewhere, and if present, it is frequently extranodal. Several cases of PALs, with central nervous system (CNS) involvement, gastrointestinal tract or other endocrine organs involvement, have been reported in Western literature. W...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2002.43.3.385

    authors: Hahn JS,Choi HS,Suh CO,Lee WJ

    更新日期:2002-06-01 00:00:00

  • Endothelial dysfunction and alteration of nitric oxide/ cyclic GMP pathway in patients with exercise-induced hypertension.

    abstract::The diagnostic and prognostic implication of exaggerated blood pressure response to exercise have been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbidity. Endothelial dysfunction has been demonstrated in patients with atherosclerosis and as a risk factor for...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.6.1014

    authors: Chang HJ,Chung JH,Choi BJ,Choi TY,Choi SY,Yoon MH,Hwang GS,Shin JH,Tahk SJ,Choi BI

    更新日期:2003-12-30 00:00:00

  • Change in Pulmonary Function after Incentive Spirometer Exercise in Children with Spastic Cerebral Palsy: A Randomized Controlled Study.

    abstract:PURPOSE:The aim of this study was to investigate the effect of incentive spirometer exercise (ISE) on pulmonary function and maximal phonation time (MPT) in children with spastic cerebral palsy (CP). MATERIALS AND METHODS:Fifty children with CP were randomly assigned to two groups: the experimental group and the contr...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2016.57.3.769

    authors: Choi JY,Rha DW,Park ES

    更新日期:2016-05-01 00:00:00

  • Quantitative EMG changes during 12-week DeLorme's axiom strength training.

    abstract::Strength training is one of the most common exercises practiced in the field of physical therapy or sports training. However, limited methodology is available to evaluate its effect on the target muscle. This study aimed to test the hypothesis that surface electromyographic (EMG) data from both isometric and isotonic ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.1.93

    authors: Shin HK,Cho SH,Lee YH,Kwon OY

    更新日期:2006-02-28 00:00:00

  • Selective neck dissection for clinically node-positive oral cavity squamous cell carcinoma.

    abstract:PURPOSE:The treatment of a clinically node-positive (cN+) neck is important in the management of oral cavity squamous cell carcinoma (OSCC). However, the extent of neck dissection (ND) remains controversial. The purpose of our study was to evaluate whether level IV or V can be excluded in therapeutic ND for cN+ OSCC pa...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.1.139

    authors: Shin YS,Koh YW,Kim SH,Choi EC

    更新日期:2013-01-01 00:00:00

  • C-Reactive Protein to Serum Albumin Ratio Is an Independent Predictor of All-Cause Mortality in Patients with ANCA-Associated Vasculitis.

    abstract:PURPOSE:We investigated whether C-reactive protein (CRP) to serum albumin ratio (CAR) could be an independent predictor of all-cause mortality in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). MATERIALS AND METHODS:We retrospectively reviewed the medical records of 170 patients w...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.7.865

    authors: Moon JS,Ahn SS,Park YB,Lee SK,Lee SW

    更新日期:2018-09-01 00:00:00

  • Neurologic recovery according to early magnetic resonance imaging findings in traumatic cervical spinal cord injuries.

    abstract::The aim of this study was to determine the usefulness of early magnetic resonance imaging findings in predicting neurologic recovery at or below the injured level in traumatic cervical spinal cord injuries. Thirty patients with traumatic cervical spinal cord injuries were included. All of the patients received a magne...

    journal_title:Yonsei medical journal

    pub_type: 临床试验,杂志文章

    doi:10.3349/ymj.2005.46.3.379

    authors: Shin JC,Kim DY,Park CI,Kim YW,Ohn SH

    更新日期:2005-06-30 00:00:00

  • VEGF Promoter Polymorphism Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese Population.

    abstract:PURPOSE:Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS:In this study, we hypothesized that single nucleotide variants in vascular endothelial growth factor (VEGF) gene may alter gene function and expression and may be as...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2017.58.2.305

    authors: Zhuo Y,Zeng Q,Zhang P,Li G,Xie Q,Cheng Y

    更新日期:2017-03-01 00:00:00

  • Progressive change in joint degeneration in patients with knee or hip osteoarthritis treated with fentanyl in a randomized trial.

    abstract:PURPOSE:Opioids improve pain from knee and hip osteoarthritis (OA) and decrease the functional impairment of patients. However, there is a possibility that opioids induce analgesia and suppress the physiological pain of OA in patients, thereby inducing the progression of OA changes in these patients. The purpose of the...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2014.55.5.1379

    authors: Fujii T,Takana K,Orita S,Inoue G,Ochiai N,Kuniyoshi K,Aoki Y,Ishikawa T,Miyagi M,Kamoda H,Suzuki M,Sakuma Y,Kubota G,Oikawa Y,Inage K,Sainoh T,Sato J,Yamauchi K,Toyone T,Nakamura J,Kishida S,Takahashi K,Ohtori

    更新日期:2014-09-01 00:00:00

  • Sensory neuronal change after intravesical electrical stimulation in spinailized rat.

    abstract::The clinical benefits of intravesical electrical stimulation (IVES) in patients with increased residual urine or reduced bladder capacity have been reported. However, studies on the underlying mechanism of IVES has been limited to the Adelta afferent and parasympathetic neurons. This study investigated the changes in ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2002.43.5.652

    authors: Hong CH,Kim JH,Noh JY,Gil YC,Lee HY,Lee WH,Han SW

    更新日期:2002-10-01 00:00:00

  • The effect of selective tibial neurotomy and rehabilitation in a quadriplegic patient with ankle spasticity following traumatic brain injury.

    abstract::Ankle spasticity following brain injury leads to abnormal posture and joint contracture; making standing or walking impossible. This study investigates the efficacy of selective tibial neurotomy (STN) and intensive rehabilitation in a patient who suffered ankle spasticity after brain injury. This case describes a 37-y...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.4.743

    authors: Jang SH,Park SM,Kim SH,Ahn SH,Cho YW,Ahn MO

    更新日期:2004-08-31 00:00:00

  • Modified Peritoneal Dialysis Catheter Insertion: Comparison with a Conventional Method.

    abstract:PURPOSE:The conventional trocar and cannula method in peritoneal dialysis (PD) catheter insertion has its limitation in clinical setting. The aim of this study was to compare a modified method for percutaneous PD catheter insertion with the conventional method, and demonstrate advantages of the modified method. MATERI...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.4.981

    authors: Lee YK,Yang PS,Park KS,Choi KH,Kim BS

    更新日期:2015-07-01 00:00:00

  • Lactobacillus casei subspecies casei endocarditis--a case report.

    abstract::Lactobacillus sp., generally considered to be a harmless indigenous bacteria of the mucous membrane, occasionally causes serious infections. Lactobacillus endocarditis is a very rare disease, and no case has been reported in Korea. Gram-positive bacilli were isolated from blood cultures of a 41-year-old man with clini...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1991.32.1.69

    authors: Chong Y,Lim HS,Lee SY,Cho SY

    更新日期:1991-03-01 00:00:00

  • Nonspecific interstitial pneumonitis after bortezomib and thalidomide treatment in a multiple myeloma patient.

    abstract::Bortezomib, an inhibitor of 26S proteosome, is recently approved treatment option for multiple myeloma. Thalidomide, a drug with immunomodulating and antiangiogenic effects, has also shown promise as an effective treatment in multiple myeloma. Pulmonary complications are believed to be rare, especially interstitial lu...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.3.448

    authors: Kang W,Kim JS,Cho SH,Kim SK,Chang J,Park MS

    更新日期:2010-05-01 00:00:00

  • mTOR Signaling Combined with Cancer Stem Cell Markers as a Survival Predictor in Stage II Colorectal Cancer.

    abstract:PURPOSE:Wnt and mammalian target of rapamycin (mTOR) are major molecular signaling pathways associated with the development and progression of tumor, as well as the maintenance and proliferation of cancer stem cells (CSCs), in colorectal cancer (CRC). Identifying patients at risk of poor prognosis is important to deter...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2020.61.7.572

    authors: Chang JY,Kim JH,Kang J,Park Y,Park SJ,Cheon JH,Kim WH,Kim H,Park JJ,Kim TI

    更新日期:2020-07-01 00:00:00

  • Treatment of osteofibrous dysplasia and associated lesions.

    abstract:PURPOSE:To report long term treatment outcomes of osteofibrous dysplasia and association with adamantinoma. PATIENTS AND METHODS:From January 1984 to July 2001, 14 patients with osteofibrous dysplasia were followed for an average of 108 months (78 to 260 months). Our patient group consisted of 6 men and 8 women, with ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.3.502

    authors: Hahn SB,Kim SH,Cho NH,Choi CJ,Kim BS,Kang HJ

    更新日期:2007-06-30 00:00:00

  • Donor bone marrow infusion in deceased and living donor renal transplantation.

    abstract::The infusion and persistence in a transplant recipient of donor-derived bone marrow cells (DBMC) of multi-lineage can lead to a state of permanent chimerism. In solid vascular organ transplantation, the donor bone marrow lineage cells can even be derived from the transplant organ, and these cells can be detected in ve...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2004.45.6.998

    authors: Ciancio G,Burke GW,Moon J,Garcia-Morales R,Rosen A,Esquenazi V,Mathew J,Jin Y,Miller J

    更新日期:2004-12-31 00:00:00

  • Effect of induced and spontaneous hypothermia on survival time of uncontrolled hemorrhagic shock rat model.

    abstract::We examined the hypothesis that mild hypothermia (rectal temperature 34 degrees C) results in the same survival time, whether induced spontaneously or intentionally, during untreated, lethal, uncontrolled hemorrhagic shock in rats. Sixty-four Sprague-Dawley male rats were randomly assigned to normothermia (Nth) (n=19)...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2002.43.4.511

    authors: Lee KR,Chung SP,Park IC,Kim SH

    更新日期:2002-08-01 00:00:00

  • Sex difference of type 2 diabetes affected by abdominal obesity versus overall obesity.

    abstract:PURPOSE:This research compares the predictive value of the abdominal obesity indicator, waist circumference (WC), and the overall obesity indicator, body mass index (BMI), among men and women with regard to type 2 diabetes. MATERIALS AND METHODS:This study used data collected from 4,400 households selected by a strati...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.6.850

    authors: Paek KW,Chun KH

    更新日期:2010-11-01 00:00:00

  • Morphological characteristics of the developing human brain during the embryonic period.

    abstract::Many features of the developing nervous system are visible from external observations of intact human embryos. In this study, a photographic atlas from the 4th to the 7th week after ovulation (Carnegie stages 10-18) is provided. The neural folds began to fuse at stage 10, and the rostral and caudal neuropore were clos...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.1.26

    authors: Yoon H,Shin YS,Lee KC,Park HW

    更新日期:1997-02-01 00:00:00

  • Spontaneous rupture of a functioning adrenocortical carcinoma.

    abstract::Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis, and it can be classified as either a functional or nonfunctional tumor. Affected patients usually present with abdominal pain or with symptoms related to the mass effect or hormonal activity of the tumor. Several cases of spontaneously ruptured n...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.6.974

    authors: Chung JO,Cho DH,Lee JH,Kwon DD,Chung DJ,Chung MY

    更新日期:2010-11-01 00:00:00

  • Lateralization of cognitive functions in aphasia after right brain damage.

    abstract:PURPOSE:The lateralization of cognitive functions in crossed aphasia in dextrals (CAD) has been explored and compared mainly with cases of aphasia with left hemisphere damage. However, comparing the neuropsychological aspects of CAD and aphasia after right brain damage in left-handers (ARL) could potentially provide mo...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.3.486

    authors: Ha JW,Pyun SB,Hwang YM,Sim H

    更新日期:2012-05-01 00:00:00

  • Acute lymphoblastic leukemia associated with brucellosis in two patients with fever and pancytopenia.

    abstract::Brucellosis is a disease involving the lymphoproliferative system, which may lead to changes in the hematological parameters; however, pancytopenia is a rare finding. However, malignant diseases in association with brucellosis are rarely the cause of pancytopenia. Herein, two cases with fever and pancytopenia, diagnos...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.5.741

    authors: Eser B,Altuntas F,Soyuer I,Er O,Canoz O,Coskun HS,Cetin M,Unal A

    更新日期:2006-10-31 00:00:00

  • Clinical Efficacy of Subcutaneous Allergen Immunotherapy in Patients with Atopic Dermatitis.

    abstract:PURPOSE:The clinical usefulness of subcutaneous allergen immunotherapy (SCIT) in the treatment of atopic dermatitis (AD) is still controversial. We analyzed the clinical efficacy of SCIT in patients with AD and the clinical characteristics of patients showing a favorable clinical response to the treatment. MATERIALS A...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.6.1420

    authors: Nahm DH,Kim ME,Kwon B,Cho SM,Ahn A

    更新日期:2016-11-01 00:00:00

  • Aldehyde Dehydrogenase 2 (ALDH2) Polymorphism and the Risk of Alcoholic Liver Cirrhosis among East Asians: A Meta-Analysis.

    abstract:PURPOSE:The aldehyde dehydrogenase 2 (ALDH2) gene has been implicated in the development of alcoholic liver cirrhosis (ALC) in East Asians. However, the results are inconsistent. In this study, a meta-analysis was performed to assess the associations between the ALDH2 polymorphism and the risk of ALC. MATERIALS AND ME...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,meta分析

    doi:10.3349/ymj.2016.57.4.879

    authors: He L,Deng T,Luo H

    更新日期:2016-07-01 00:00:00

  • Ultrasonic energy in endoscopic surgery.

    abstract::The Harmonic Scalpel made by Ultracision is a system for endoscopic cutting. The energy source is vibration. The power box is attached to a forceps or blade, and the vibrational frequency of the blade approaches 55,500 cycles/second. This causes a knife-like action of the blade through tissue, with enough heating to c...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1999.40.6.545

    authors: Lee SJ,Park KH

    更新日期:1999-12-01 00:00:00

  • Medical students' attitudes toward psychiatry in a Korean medical college.

    abstract::One hundred fifty four senior medical students responded to a questionnaire regarding attitudes toward psychiatry. A majority of students were favorable about psychiatric education, psychiatric consultation, and psychoanalysis. Students with more interest in psychiatry as a career showed both positive and negative vie...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1990.31.1.60

    authors: Koh KB

    更新日期:1990-03-01 00:00:00

  • Blockade of VEGFR-1 and VEGFR-2 enhances paclitaxel sensitivity in gastric cancer cells.

    abstract:PURPOSE:Hypoxia-inducible factor-1α (HIF-1α) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1α. Recent reports suggested that HIF-1α also mediated the induction of class III β-tubulin (TUBB3) in hypoxia. TUBB3 confers resistance...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.2.374

    authors: Hwang JE,Lee JH,Park MR,Kim DE,Bae WK,Shim HJ,Cho SH,Chung IJ

    更新日期:2013-03-01 00:00:00

  • Intrinsic and extrinsic regulation of innate immune receptors.

    abstract::Pattern recognition receptors (PRRs) in innate immune cells play a pivotal role in the first line of host defense system. PRRs recognize pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs) to initiate and regulate innate and adaptive immune responses. PRRs include Toll-like r...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2011.52.3.379

    authors: Jeong E,Lee JY

    更新日期:2011-05-01 00:00:00

  • Spontaneous dissecting aneurysm of the intracranial vertebral artery: management strategies.

    abstract:PURPOSE:Pathogenesis and treatment of spontaneous dissecting aneurysm of the intracranial vertebral artery (VA) remain controversial. This study was designed to provide management strategies and to improve management outcome in patients with these aneurysms. MATERIALS AND METHODS:Among a total of 1,990 patients treate...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.3.425

    authors: Lee JW,Jung JY,Kim YB,Huh SK,Kim DI,Lee KC

    更新日期:2007-06-30 00:00:00