Abstract:
PURPOSE:Decision to perform concurrent ipsilateral thyroidectomy on patients with hypopharyngeal cancer is important, and unnecessary thyroidectomy should be avoided if oncologically feasible. We hypothesized that concurrent ipsilateral thyroidectomy is not routinely required to prevent occult metastasis. This study aimed to determine the prevalence of histological thyroid invasion in patients with hypopharyngeal cancer, and to refine the indications for prophylactic ipsilateral thyroidectomy in patients with hypopharyngeal cancer. MATERIALS AND METHODS:A retrospective review of the medical records from the Department of Otolaryngology at Yonsei University College of Medicine was conducted from January 1994 to December 2009. A total of 49 patients underwent laryngopharyngectomy with thyroidectomy as a primary treatment of hypopharyngeal cancer. RESULTS:The incidence of thyroid gland involvement was 10.2%. The most common route of invasion was direct extension through the thyroid cartilage. Thyroid cartilage invasion (p=0.034) was the most significant factor associated with thyroid invasion. Disease-specific survival at 5 years was lower in patients with than without thyroid gland invasion (26.7% vs. 55.2%, respectively; p=0.032). Disease-free survival at 5 years was also lower in patients with than without thyroid gland invasion (20.0% vs. 52.1%, respectively; p=0.024). CONCLUSION:Ipsilateral thyroidectomy in combination with total laryngopharyngectomy is indicated when invasion of the thyroid cartilage is suspected in patients with hypopharyngeal cancer.
journal_name
Yonsei Med Jjournal_title
Yonsei medical journalauthors
Chang JW,Koh YW,Chung WY,Hong SW,Choi ECdoi
10.3349/ymj.2015.56.3.812subject
Has Abstractpub_date
2015-05-01 00:00:00pages
812-8issue
3eissn
0513-5796issn
1976-2437pii
201505812journal_volume
56pub_type
杂志文章abstract::A previously healthy 44-year-old male was admitted with the chief complaint of intermittent gross hematuria. On initial ultrasonographic and CT examination, a grossly protruding intravesical tumor was noted and, under the impression of a malignant bladder tumor, transurethral resection was performed. The histological ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2000.41.2.273
更新日期:2000-04-01 00:00:00
abstract::Living donor liver transplantation (LDLT) was first successfully performed on a child in 1990 and the Shinshu group performed the same procedure on an adult for the first time in 1994. Over the past few years adult LDLT has been increasing worldwide because of the severe shortage of cadaveric organs, especially in loc...
journal_title:Yonsei medical journal
pub_type: 杂志文章,评审
doi:10.3349/ymj.2004.45.6.1076
更新日期:2004-12-31 00:00:00
abstract:PURPOSE:The purpose of this study is to assess patient attitudes towards anti-glaucoma medication and their association with adherence, visual quality of life, and personality traits. MATERIALS AND METHODS:One hundred and forty-seven glaucoma patients were enrolled this study. The participants were divided into 'pharm...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2010.51.2.261
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous immunoglobulin (IVIG). PATIENTS AND METHODS:The patients who had persistent or recrudescent fever after treatment with IVIG were subse...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2008.49.5.714
更新日期:2008-10-31 00:00:00
abstract::Klinefelter's syndrome is one of the most common forms of primary hypogonadism and infertility in males. It is characterized by small and firm testes, gynecomastia, azoospermia, and an elevated gonadotropin level. The frequencies of diabetes mellitus, breast cancer, and germ cell neoplasia increases in Klinefelter's s...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2004.45.2.341
更新日期:2004-04-30 00:00:00
abstract:PURPOSE:Genes of the HoxD cluster play a major role in vertebrate limb development, and changes that modify the Hoxd12 locus affect other genes also, suggesting that HoxD function is coordinated by a control mechanism involving multiple genes during limb morphogenesis. In this study, mutant phenotypes were produced by ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2008.49.6.965
更新日期:2008-12-31 00:00:00
abstract:PURPOSE:To evaluate the efficacy of minimal stimulation using discretely administered gonadotropin combined with clomiphene citrate (CC) or letrozole (LTZ) for intrauterine insemination (IUI) cycles. MATERIALS AND METHODS:Total 257 IUI cycles from 158 infertile couples were assessed. A CC dose of 100 mg/day (n=126 cyc...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2015.56.2.490
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:Several studies have demonstrated that psychiatric disorders such as anxiety, depression and panic attack are associated with syncope, especially vasovagal and unexplained syncope (US). The aim of this study was to compare the prevalence of anxiety and depression between patients with neurally mediated syncope ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2013.54.3.583
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Growing evidence suggests that hypoadiponectinemia may play a significant role in the development of metabolic syndrome (MetS). Therefore, the relationships between serum adiponectin with MetS and components of MetS were investigated in non-diabetic samples of drawn from the Koreans general population. MATERIA...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2011.52.2.234
更新日期:2011-03-01 00:00:00
abstract::We evaluated the one-stage intraoperative adjustment strabismus surgery with adjustable suture under topical anesthesia. Medical records of the patients who had intraoperative adjustment surgery under topical anesthesia for horizontal or vertical strabismus in our hospital from March 1997 to March 2003 with follow-up ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2006.47.5.667
更新日期:2006-10-31 00:00:00
abstract:PURPOSE:This study aimed to compare the effects of ticagrelor and clopidogrel on early neointimal healing assessed with optical coherence tomography (OCT) after drug-eluting stent (DES) implantation in patients with acute myocardial infarction (AMI). MATERIALS AND METHODS:AMI patients were randomly assigned to either ...
journal_title:Yonsei medical journal
pub_type: 杂志文章,随机对照试验
doi:10.3349/ymj.2018.59.5.624
更新日期:2018-07-01 00:00:00
abstract::Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein expressed in hepatocytes rather than in immune cells affects the CD8+ T cell response. In order to transduce genes selectiv...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2005.46.6.827
更新日期:2005-12-31 00:00:00
abstract::A weight-holding tremor is a rare type of hand tremor that occurs only when someone holds some weight. Here we report three cases of isolated weight-holding tremors, of which one patient was diagnosed with Parkinson's disease (PD) and the others as a variant of essential tremor (ET). A 68-year-old woman presented with...
journal_title:Yonsei medical journal
pub_type:
doi:10.3349/ymj.2020.61.7.644
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS:Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptosis was first an...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2008.49.3.486
更新日期:2008-06-30 00:00:00
abstract:PURPOSE:Simple decompression of the ulnar nerve has outcomes similar to anterior transposition for cubital tunnel syndrome; however, there is no consensus on the proper technique for patients with an unstable ulnar nerve. We hypothesized that 1) simple decompression or anterior ulnar nerve transposition, depending on n...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2016.57.2.455
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal g...
journal_title:Yonsei medical journal
pub_type: 杂志文章,随机对照试验
doi:10.3349/ymj.2007.48.2.295
更新日期:2007-04-30 00:00:00
abstract::Dieulafoy's lesion is an uncommon cause of gastrointestinal bleeding. Hemorrhage occurs through mucosal erosion from an abnormally dilated submucosal artery. Although Dieulafoy's lesion is usually located in the stomach, it may occur anywhere in the gastrointestinal tract. We report here on a case of jejunal Dieulafoy...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2005.46.3.445
更新日期:2005-06-30 00:00:00
abstract::Brain is a logical target of free radical damage, considering the large lipid content of myelin sheaths and the high rate of brain oxidative metabolism. Thus, the hypothesis that free radicals may be involved in the pathogenesis of certain CNS diseases has gained increasing popularity in recent years. In CNS ischemia-...
journal_title:Yonsei medical journal
pub_type: 杂志文章,评审
doi:10.3349/ymj.1993.34.1.1
更新日期:1993-03-01 00:00:00
abstract:PURPOSE:We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. MATERIALS AND METHODS:The sample included 61 aggressive patients as well as 104 non-aggressive patients from psychiatric hospitals and 335 healthy volunteers in Korea. Blood s...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2010.51.1.27
更新日期:2010-01-01 00:00:00
abstract::Pulse oximetry is a noninvasive technique for measuring O2 saturation (SpO2) continuously. We applied pulse oximetry to 9 pediatric patients with tetralogy of Fallot during shunt surgery. Arterial oxygen tensions (PaO2) and saturations (SaO2) were also measured at the time of postinduction, just before the shunt, afte...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.1989.30.1.12
更新日期:1989-01-01 00:00:00
abstract::Echocardiographic automatic boundary detection (ABD) is a new on-line technique which automatically outlines the left ventricular endocardial border and instantly calculates the left ventricular area and volume from two dimensional echocardiographic images. To determine if left ventricular ejection fraction (LVEF) can...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.1996.37.6.385
更新日期:1996-12-01 00:00:00
abstract::Contrast-enhanced multi-detector row spiral computed tomography (MDCT) was introduced as a promising noninvasive method for vascular imaging. This study examined the accuracy of this technique for detecting significant coronary artery stenoses. Both MDCT(Sensation 16, Siemens, Germany, 12x0.75 mm collimation and 0.42 ...
journal_title:Yonsei medical journal
pub_type: 临床试验,杂志文章
doi:10.3349/ymj.2005.46.1.86
更新日期:2005-02-28 00:00:00
abstract:PURPOSE:Numerous studies have assessed the association of SP110 gene variants with tuberculosis (TB), but the results were inconsistent. Through a comprehensive review and meta-analysis, our study aimed to clarify the nature of genetic risks contributed by 11 polymorphisms for the development of TB. MATERIALS AND METH...
journal_title:Yonsei medical journal
pub_type: 杂志文章,meta分析,评审
doi:10.3349/ymj.2017.58.1.165
更新日期:2017-01-01 00:00:00
abstract::The infusion and persistence in a transplant recipient of donor-derived bone marrow cells (DBMC) of multi-lineage can lead to a state of permanent chimerism. In solid vascular organ transplantation, the donor bone marrow lineage cells can even be derived from the transplant organ, and these cells can be detected in ve...
journal_title:Yonsei medical journal
pub_type: 杂志文章,评审
doi:10.3349/ymj.2004.45.6.998
更新日期:2004-12-31 00:00:00
abstract::CSF flow dynamics has been known to have a key role the pathogenesis of syringomyelia. Our purpose was to evaluate the CSF flow pattern in syringomyelia with spatial modulation of magnetization (SPAMM) that can depict directional flow, and to determine the relationship between flow dynamics and clinical outcome after ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2002.43.1.37
更新日期:2002-02-01 00:00:00
abstract:PURPOSE:Hyperoxia has the chief biological effect of cell death. We have previously reported that cathepsin B (CB) is related to fetal alveolar type II cell (FATIIC) death and pretreatment of recombinant IL-10 (rIL-10) attenuates type II cell death during 65%-hyperoixa. In this study, we investigated what kinds of chan...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2013.54.2.445
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Tumor marker concentrations in a given specimen measured by different analyzers vary according to assay methods, epitopes for antibodies used, and reagent specificities. Although great effort in quality assessment has been instituted, discrepancies among results from different analyzers are still present. We ev...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2012.53.3.557
更新日期:2012-05-01 00:00:00
abstract::Telomeres undergo attrition with each cell division, and telomere length is associated with age-related diseases and mortality in the elderly. Estrogen can influence the attrition of telomeres by diverse mechanisms. This is a retrospective case control study that investigated the influence of long-term hormone therapy...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2005.46.4.471
更新日期:2005-08-31 00:00:00
abstract:PURPOSE:Although current guidelines recommend continuing the same antithrombotic strategy regardless of rhythm control after radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF), anticoagulation has a risk of major bleeding. We evaluated the safety of switching warfarin to aspirin in patients with succes...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2014.55.5.1238
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Lacunar stroke, in the context of small vessel disease, is a type of cerebral infarction caused by occlusion of a penetrating artery. Pulsatility index (PI) is an easily measurable parameter in Transcranial Doppler ultrasound (TCD) study. PI reflects distal cerebral vascular resistance and has been interpreted ...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2016.57.4.950
更新日期:2016-07-01 00:00:00