Predictors of thyroid gland involvement in hypopharyngeal squamous cell carcinoma.

Abstract:

PURPOSE:Decision to perform concurrent ipsilateral thyroidectomy on patients with hypopharyngeal cancer is important, and unnecessary thyroidectomy should be avoided if oncologically feasible. We hypothesized that concurrent ipsilateral thyroidectomy is not routinely required to prevent occult metastasis. This study aimed to determine the prevalence of histological thyroid invasion in patients with hypopharyngeal cancer, and to refine the indications for prophylactic ipsilateral thyroidectomy in patients with hypopharyngeal cancer. MATERIALS AND METHODS:A retrospective review of the medical records from the Department of Otolaryngology at Yonsei University College of Medicine was conducted from January 1994 to December 2009. A total of 49 patients underwent laryngopharyngectomy with thyroidectomy as a primary treatment of hypopharyngeal cancer. RESULTS:The incidence of thyroid gland involvement was 10.2%. The most common route of invasion was direct extension through the thyroid cartilage. Thyroid cartilage invasion (p=0.034) was the most significant factor associated with thyroid invasion. Disease-specific survival at 5 years was lower in patients with than without thyroid gland invasion (26.7% vs. 55.2%, respectively; p=0.032). Disease-free survival at 5 years was also lower in patients with than without thyroid gland invasion (20.0% vs. 52.1%, respectively; p=0.024). CONCLUSION:Ipsilateral thyroidectomy in combination with total laryngopharyngectomy is indicated when invasion of the thyroid cartilage is suspected in patients with hypopharyngeal cancer.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Chang JW,Koh YW,Chung WY,Hong SW,Choi EC

doi

10.3349/ymj.2015.56.3.812

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

812-8

issue

3

eissn

0513-5796

issn

1976-2437

pii

201505812

journal_volume

56

pub_type

杂志文章
  • Inflammatory pseudotumor of urinary bladder.

    abstract::A previously healthy 44-year-old male was admitted with the chief complaint of intermittent gross hematuria. On initial ultrasonographic and CT examination, a grossly protruding intravesical tumor was noted and, under the impression of a malignant bladder tumor, transurethral resection was performed. The histological ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2000.41.2.273

    authors: Byun YJ,Chung BH,Kwon KW

    更新日期:2000-04-01 00:00:00

  • Revolution and refinement of surgical techniques for living donor partial liver transplantation.

    abstract::Living donor liver transplantation (LDLT) was first successfully performed on a child in 1990 and the Shinshu group performed the same procedure on an adult for the first time in 1994. Over the past few years adult LDLT has been increasing worldwide because of the severe shortage of cadaveric organs, especially in loc...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2004.45.6.1076

    authors: Dulundu E,Sugawara Y,Makuuchi M

    更新日期:2004-12-31 00:00:00

  • Drug attitude and adherence to anti-glaucoma medication.

    abstract:PURPOSE:The purpose of this study is to assess patient attitudes towards anti-glaucoma medication and their association with adherence, visual quality of life, and personality traits. MATERIALS AND METHODS:One hundred and forty-seven glaucoma patients were enrolled this study. The participants were divided into 'pharm...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.2.261

    authors: Hong S,Kang SY,Yoon JU,Kang U,Seong GJ,Kim CY

    更新日期:2010-03-01 00:00:00

  • Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease.

    abstract:PURPOSE:The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous immunoglobulin (IVIG). PATIENTS AND METHODS:The patients who had persistent or recrudescent fever after treatment with IVIG were subse...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.5.714

    authors: Lee TJ,Kim KH,Chun JK,Kim DS

    更新日期:2008-10-31 00:00:00

  • Graves' disease associated with Klinefelter's syndrome.

    abstract::Klinefelter's syndrome is one of the most common forms of primary hypogonadism and infertility in males. It is characterized by small and firm testes, gynecomastia, azoospermia, and an elevated gonadotropin level. The frequencies of diabetes mellitus, breast cancer, and germ cell neoplasia increases in Klinefelter's s...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.2.341

    authors: Park JS,Kim CS,Nam JY,Kim DM,Yoon SJ,Ahn CW,Cha BS,Lim SK,Kim KR,Lee HC,Huh KB

    更新日期:2004-04-30 00:00:00

  • Point mutation of Hoxd12 in mice.

    abstract:PURPOSE:Genes of the HoxD cluster play a major role in vertebrate limb development, and changes that modify the Hoxd12 locus affect other genes also, suggesting that HoxD function is coordinated by a control mechanism involving multiple genes during limb morphogenesis. In this study, mutant phenotypes were produced by ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.6.965

    authors: Cho KW,Kim JY,Cho JW,Cho KH,Song CW,Jung HS

    更新日期:2008-12-31 00:00:00

  • Minimal stimulation using gonadotropin combined with clomiphene citrate or letrozole for intrauterine insemination.

    abstract:PURPOSE:To evaluate the efficacy of minimal stimulation using discretely administered gonadotropin combined with clomiphene citrate (CC) or letrozole (LTZ) for intrauterine insemination (IUI) cycles. MATERIALS AND METHODS:Total 257 IUI cycles from 158 infertile couples were assessed. A CC dose of 100 mg/day (n=126 cyc...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.2.490

    authors: Yun BH,Chon SJ,Park JH,Seo SK,Cho S,Choi YS,Kim SH,Lee BS

    更新日期:2015-03-01 00:00:00

  • Prevalence and clinical factors of anxiety and depression in neurally mediated and unexplained syncope.

    abstract:PURPOSE:Several studies have demonstrated that psychiatric disorders such as anxiety, depression and panic attack are associated with syncope, especially vasovagal and unexplained syncope (US). The aim of this study was to compare the prevalence of anxiety and depression between patients with neurally mediated syncope ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.3.583

    authors: Lee SH,Park SJ,Byeon K,On YK,Yim HR,Kim JS

    更新日期:2013-05-01 00:00:00

  • Relationships between serum adiponectin with metabolic syndrome and components of metabolic syndrome in non-diabetic Koreans: ARIRANG study.

    abstract:PURPOSE:Growing evidence suggests that hypoadiponectinemia may play a significant role in the development of metabolic syndrome (MetS). Therefore, the relationships between serum adiponectin with MetS and components of MetS were investigated in non-diabetic samples of drawn from the Koreans general population. MATERIA...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2011.52.2.234

    authors: Koh SB,Yoon J,Kim JY,Yoo BS,Lee SH,Park JK,Choe KH

    更新日期:2011-03-01 00:00:00

  • Intraoperative adjustment in strabismus surgery under topical anesthesia.

    abstract::We evaluated the one-stage intraoperative adjustment strabismus surgery with adjustable suture under topical anesthesia. Medical records of the patients who had intraoperative adjustment surgery under topical anesthesia for horizontal or vertical strabismus in our hospital from March 1997 to March 2003 with follow-up ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2006.47.5.667

    authors: Chang YH,Ryu IH,Han SH,Lee SJ,Lee JB

    更新日期:2006-10-31 00:00:00

  • Randomized Comparison of Strut Coverage between Ticagrelor and Clopidogrel in Acute Myocardial Infarction at 3-Month Optical Coherence Tomography.

    abstract:PURPOSE:This study aimed to compare the effects of ticagrelor and clopidogrel on early neointimal healing assessed with optical coherence tomography (OCT) after drug-eluting stent (DES) implantation in patients with acute myocardial infarction (AMI). MATERIALS AND METHODS:AMI patients were randomly assigned to either ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2018.59.5.624

    authors: Kim C,Kim BK,Hong SJ,Ahn CM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y

    更新日期:2018-07-01 00:00:00

  • Expression of hepatitis C virus core protein in hepatocytes does not modulate proliferation or apoptosis of CD8+ T cells.

    abstract::Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein expressed in hepatocytes rather than in immune cells affects the CD8+ T cell response. In order to transduce genes selectiv...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.6.827

    authors: Jin YH,Crispe IN,Park S

    更新日期:2005-12-31 00:00:00

  • Is an Isolated Weight-Holding Tremor a New Subtype of Isometric Tremor?

    abstract::A weight-holding tremor is a rare type of hand tremor that occurs only when someone holds some weight. Here we report three cases of isolated weight-holding tremors, of which one patient was diagnosed with Parkinson's disease (PD) and the others as a variant of essential tremor (ET). A 68-year-old woman presented with...

    journal_title:Yonsei medical journal

    pub_type:

    doi:10.3349/ymj.2020.61.7.644

    authors: Yong SW,Park DG,Yoon JH,Baik JS

    更新日期:2020-07-01 00:00:00

  • Protective effect of ultra low molecular weight heparin on glutamate-induced apoptosis in cortical cells.

    abstract:PURPOSE:To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS:Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptosis was first an...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2008.49.3.486

    authors: Yu TG,Zhang QZ,Zhang ZG,Wang WW,Ji SL,Du GH

    更新日期:2008-06-30 00:00:00

  • Factors Influencing Outcomes after Ulnar Nerve Stability-Based Surgery for Cubital Tunnel Syndrome: A Prospective Cohort Study.

    abstract:PURPOSE:Simple decompression of the ulnar nerve has outcomes similar to anterior transposition for cubital tunnel syndrome; however, there is no consensus on the proper technique for patients with an unstable ulnar nerve. We hypothesized that 1) simple decompression or anterior ulnar nerve transposition, depending on n...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.2.455

    authors: Kang HJ,Oh WT,Koh IH,Kim S,Choi YR

    更新日期:2016-03-01 00:00:00

  • Intra-synovial ropivacaine and morphine for pain relief after total knee arthroplasty: a prospective, randomized, double blind study.

    abstract:PURPOSE:Several analgesic techniques are available for pain management after a major operation. MATERIALS AND METHODS:From December 2005 to February 2006, a prospective, double-blind study was performed involving 90 patients who had undergone a total knee arthroplasty. Patients were randomly divided into three equal g...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.3349/ymj.2007.48.2.295

    authors: Han CD,Lee DH,Yang IH

    更新日期:2007-04-30 00:00:00

  • Dieulafoy's lesion of jejunum: presenting small bowel mass and stricture.

    abstract::Dieulafoy's lesion is an uncommon cause of gastrointestinal bleeding. Hemorrhage occurs through mucosal erosion from an abnormally dilated submucosal artery. Although Dieulafoy's lesion is usually located in the stomach, it may occur anywhere in the gastrointestinal tract. We report here on a case of jejunal Dieulafoy...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.3.445

    authors: Kim JK,Jo BJ,Lee KM,Sun JS,Won JH,Kim MW,Han JH

    更新日期:2005-06-30 00:00:00

  • Oxygen, antioxidants and brain dysfunction.

    abstract::Brain is a logical target of free radical damage, considering the large lipid content of myelin sheaths and the high rate of brain oxidative metabolism. Thus, the hypothesis that free radicals may be involved in the pathogenesis of certain CNS diseases has gained increasing popularity in recent years. In CNS ischemia-...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.1993.34.1.1

    authors: Choi BH

    更新日期:1993-03-01 00:00:00

  • No evidence of an association between A218C polymorphism of the tryptophan hydroxylase 1 gene and aggression in schizophrenia in a Korean population.

    abstract:PURPOSE:We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. MATERIALS AND METHODS:The sample included 61 aggressive patients as well as 104 non-aggressive patients from psychiatric hospitals and 335 healthy volunteers in Korea. Blood s...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.1.27

    authors: Kim YR,Lee JY,Min SK

    更新日期:2010-01-01 00:00:00

  • Pulse oximetry during shunt surgery in pediatric patients with tetralogy of fallot.

    abstract::Pulse oximetry is a noninvasive technique for measuring O2 saturation (SpO2) continuously. We applied pulse oximetry to 9 pediatric patients with tetralogy of Fallot during shunt surgery. Arterial oxygen tensions (PaO2) and saturations (SaO2) were also measured at the time of postinduction, just before the shunt, afte...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1989.30.1.12

    authors: Oh HK,Park WK,Nam SH,Bang SO

    更新日期:1989-01-01 00:00:00

  • Real-time determination of left ventricular ejection fraction by automatic boundary detection in patients with dilated cardiomyopathy: a comparison with radionuclide ventriculography.

    abstract::Echocardiographic automatic boundary detection (ABD) is a new on-line technique which automatically outlines the left ventricular endocardial border and instantly calculates the left ventricular area and volume from two dimensional echocardiographic images. To determine if left ventricular ejection fraction (LVEF) can...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1996.37.6.385

    authors: Ha JW,Chung N,Choe KH,Kwan J,Rim SJ,Jang Y,Kim JY,Oh EK,Lee YJ,Shim WH,Cho SY,Kim SS

    更新日期:1996-12-01 00:00:00

  • The utility of multi-detector row spiral CT for detection of coronary artery stenoses.

    abstract::Contrast-enhanced multi-detector row spiral computed tomography (MDCT) was introduced as a promising noninvasive method for vascular imaging. This study examined the accuracy of this technique for detecting significant coronary artery stenoses. Both MDCT(Sensation 16, Siemens, Germany, 12x0.75 mm collimation and 0.42 ...

    journal_title:Yonsei medical journal

    pub_type: 临床试验,杂志文章

    doi:10.3349/ymj.2005.46.1.86

    authors: Moon JY,Chung N,Choi BW,Choe KO,Seo HS,Ko YG,Kang SM,Ha JW,Rim SJ,Jang Y,Shim WH,Cho SY

    更新日期:2005-02-28 00:00:00

  • Certain Polymorphisms in SP110 Gene Confer Susceptibility to Tuberculosis: A Comprehensive Review and Updated Meta-Analysis.

    abstract:PURPOSE:Numerous studies have assessed the association of SP110 gene variants with tuberculosis (TB), but the results were inconsistent. Through a comprehensive review and meta-analysis, our study aimed to clarify the nature of genetic risks contributed by 11 polymorphisms for the development of TB. MATERIALS AND METH...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.3349/ymj.2017.58.1.165

    authors: Zhang S,Wang XB,Han YD,Wang C,Zhou Y,Zheng F

    更新日期:2017-01-01 00:00:00

  • Donor bone marrow infusion in deceased and living donor renal transplantation.

    abstract::The infusion and persistence in a transplant recipient of donor-derived bone marrow cells (DBMC) of multi-lineage can lead to a state of permanent chimerism. In solid vascular organ transplantation, the donor bone marrow lineage cells can even be derived from the transplant organ, and these cells can be detected in ve...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2004.45.6.998

    authors: Ciancio G,Burke GW,Moon J,Garcia-Morales R,Rosen A,Esquenazi V,Mathew J,Jin Y,Miller J

    更新日期:2004-12-31 00:00:00

  • Evaluation of CSF motion in syringomyelia with spatial modulation of magnetization (SPAMM).

    abstract::CSF flow dynamics has been known to have a key role the pathogenesis of syringomyelia. Our purpose was to evaluate the CSF flow pattern in syringomyelia with spatial modulation of magnetization (SPAMM) that can depict directional flow, and to determine the relationship between flow dynamics and clinical outcome after ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2002.43.1.37

    authors: Lee SK,Chung TS,Kim YS

    更新日期:2002-02-01 00:00:00

  • Interleukin-10 down-regulates cathepsin B expression in fetal rat alveolar type II cells exposed to hyperoxia.

    abstract:PURPOSE:Hyperoxia has the chief biological effect of cell death. We have previously reported that cathepsin B (CB) is related to fetal alveolar type II cell (FATIIC) death and pretreatment of recombinant IL-10 (rIL-10) attenuates type II cell death during 65%-hyperoixa. In this study, we investigated what kinds of chan...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.2.445

    authors: Lee HS,Kim CK

    更新日期:2013-03-01 00:00:00

  • Evaluation of the UniCel™ DxI 800 immunoassay analyzer in measuring five tumor markers.

    abstract:PURPOSE:Tumor marker concentrations in a given specimen measured by different analyzers vary according to assay methods, epitopes for antibodies used, and reagent specificities. Although great effort in quality assessment has been instituted, discrepancies among results from different analyzers are still present. We ev...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.3.557

    authors: Park Y,Park Y,Park J,Kim HS

    更新日期:2012-05-01 00:00:00

  • Effect of long-term hormone therapy on telomere length in postmenopausal women.

    abstract::Telomeres undergo attrition with each cell division, and telomere length is associated with age-related diseases and mortality in the elderly. Estrogen can influence the attrition of telomeres by diverse mechanisms. This is a retrospective case control study that investigated the influence of long-term hormone therapy...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.4.471

    authors: Lee DC,Im JA,Kim JH,Lee HR,Shim JY

    更新日期:2005-08-31 00:00:00

  • Safety and efficacy of switching anticoagulation to aspirin three months after successful radiofrequency catheter ablation of atrial fibrillation.

    abstract:PURPOSE:Although current guidelines recommend continuing the same antithrombotic strategy regardless of rhythm control after radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF), anticoagulation has a risk of major bleeding. We evaluated the safety of switching warfarin to aspirin in patients with succes...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2014.55.5.1238

    authors: Uhm JS,Won H,Joung B,Nam GB,Choi KJ,Lee MH,Kim YH,Pak HN

    更新日期:2014-09-01 00:00:00

  • The Effect of Pulsatility Index on Infarct Volume in Acute Lacunar Stroke.

    abstract:PURPOSE:Lacunar stroke, in the context of small vessel disease, is a type of cerebral infarction caused by occlusion of a penetrating artery. Pulsatility index (PI) is an easily measurable parameter in Transcranial Doppler ultrasound (TCD) study. PI reflects distal cerebral vascular resistance and has been interpreted ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2016.57.4.950

    authors: Kim Y,Lee H,An SA,Yim B,Kim J,Kim OJ,Kim WC,Kim HS,Oh SH,Kim J

    更新日期:2016-07-01 00:00:00