Abstract:
PURPOSE:Although there is no clinical evidence of nephrotoxicity with the volatile anesthetics currently used in general anesthesia, a better agent should be needed in terms of preserving postoperative renal function in living kidney donors who have only single remaining kidney. The purpose of the current retrospective, single-center study was to evaluate and compare renal function of living kidney donors after nephrectomy under either sevoflurane or desflurane anesthesia. MATERIALS AND METHODS:From January 2006 through December 2011, a total of 228 donors undergoing video assisted minilaparotomy surgery nephrectomy for kidney donation were retrospectively enrolled in the current study. The donors were categorized into a sevoflurane group or desflurane group based on the type of volatile anesthetic used. We collected laboratory data from the patients preoperatively, immediately after the operation, on the first postoperative day and on the third postoperative day. We also compared renal function of the kidney donors after donor nephrectomy by comparing creatinine level and estimated glomerular filtration rate (eGFR). RESULTS:The decrease in renal function after surgery in both groups was the most prominent on the first postoperative day. There were no significant differences between the two groups in postoperative changes of creatinine or eGFR. CONCLUSION:Sevoflurane and desflurane can be used safely as volatile anesthetics in donors undergoing nephrectomy.
journal_name
Yonsei Med Jjournal_title
Yonsei medical journalauthors
Kim MS,Lee JR,Kim MS,Ham SY,Choi SHdoi
10.3349/ymj.2013.54.5.1266subject
Has Abstractpub_date
2013-09-01 00:00:00pages
1266-72issue
5eissn
0513-5796issn
1976-2437pii
2013091266journal_volume
54pub_type
杂志文章abstract:PURPOSE:Although there is a consensus about the need for surveillance colonoscopy after endoscopic resection, the interval remains controversial for large sessile colorectal polyps. The aim of this study was to evaluate the long-term outcome and the adequate surveillance colonoscopy interval required for sessile and fl...
journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2016.57.5.1106
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journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2001.42.4.390
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journal_title:Yonsei medical journal
pub_type: 杂志文章
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
pub_type: 杂志文章,评审
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journal_title:Yonsei medical journal
pub_type: 杂志文章
doi:10.3349/ymj.2008.49.5.714
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journal_title:Yonsei medical journal
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doi:10.3349/ymj.2003.44.5.757
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journal_title:Yonsei medical journal
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doi:10.3349/ymj.1990.31.3.225
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pub_type: 杂志文章,meta分析,评审
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
pub_type: 杂志文章
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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doi:10.3349/ymj.1996.37.3.230
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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journal_title:Yonsei medical journal
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