Abstract:
BACKGROUND:So far the issue of patch tests with mite allergens in subjects not affected by atopic dermatitis (AD) has been poorly investigated. The aim of this study was to assess the frequency and intensity of responses to atopy patch tests with Dermatophagoides in non-AD subjects, and to compare them to the ones observed in AD patients. METHODS:Patch tests were performed, employing a mixture of Dermatophagoides pteronyssinus and farinae at two different concentrations (20 and 40% pet.), on 75 non-AD subjects, including 33 patients with allergic rhinitis and 42 healthy volunteers, and on 210 AD patients, as controls. RESULTS:Positive responses to 20% mite patch tests were observed in 17 non-AD subjects (23%) and in 102 AD ones (49%). The former showed a lower intensity of the responses, with a mean score of 1.4 compared with 2.1 in atopics. CONCLUSIONS:Although positive responses to mite patch tests are also observable in subjects without AD, their frequency and intensity are significantly lower compared with AD patients.
journal_name
Allergyjournal_title
Allergyauthors
Seidenari S,Giusti F,Pellacani G,Bertoni Ldoi
10.1034/j.1398-9995.2003.00142.xkeywords:
subject
Has Abstractpub_date
2003-05-01 00:00:00pages
426-9issue
5eissn
0105-4538issn
1398-9995pii
142journal_volume
58pub_type
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