当前位置： SCI文献检索 > NEUROSCIENCE期刊下所有文献 > Input-specific effects of acetylcholine on sensory and intracortical evoked responses in the "barrel cortex" in vivo.

Input-specific effects of acetylcholine on sensory and intracortical evoked responses in the "barrel cortex" in vivo.

Abstract：

:The somatosensory neocortex processes extrinsic information from the thalamus and intrinsic information from local circuits. We compared the effects of acetylcholine (Ach) on neocortical field potential responses evoked by stimulation of the whiskers and by local electrical stimulation in the upper layers of the neocortex vibrissae representation ("barrel cortex") of adult rats anesthetized with urethane. In the barrel cortex, the cholinergic system was manipulated using microdialysis by exogenous application of Ach, by increasing the endogenous levels of Ach with physostigmine and by applying specific cholinergic agonists. The results revealed that Ach selectively enhances the sensory response relative to the intracortical response. Thus, pathways in the barrel cortex are differentially regulated by cholinergic inputs.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Oldford E,Castro-Alamancos MA

doi

10.1016/s0306-4522(02)00663-2

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

769-78

issue

3

eissn

0306-4522

issn

1873-7544

pii

S0306452202006632

journal_volume

117

pub_type

杂志文章

相关文献

NEUROSCIENCE文献大全
  • Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum--III. Efferent projecting graft neurons and their relation to host afferents within the grafts.

    abstract：:Efferent projections of intrastriatally implanted striatal neurons have been studied using a combination of anterograde and retrograde axonal tracers. Adult rats subjected to a unilateral ibotenic acid lesion of the head of the caudate putamen received cell suspension grafts obtained from 14 15-day-old striatal primor...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(89)90256-x

    authors： Wictorin K,Simerly RB,Isacson O,Swanson LW,Björklund A

    更新日期：1989-01-01 00:00:00

  • Behavioral responses to injections of muscimol into the subthalamic nucleus: temporal changes after nigrostriatal lesions.

    abstract：:Changes in cellular activity in the subthalamic nucleus are a cardinal feature of Parkinson's disease and occur in rodents after lesions of the nigrostriatal pathway, a model of Parkinson's disease. GABA-ergic neurons from the globus pallidus provide a major input to the subthalamic nucleus. Previous electrophysiologi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2004.11.036

    authors： Mehta A,Menalled L,Chesselet MF

    更新日期：2005-01-01 00:00:00

  • Alteration in the levels of thyrotropin releasing hormone, substance P and enkephalins in the spinal cord, brainstem, hypothalamus and midbrain of the Wobbler mouse at different stages of the motoneuron disease.

    abstract：:The present study was undertaken to quantify selected neuropeptides (thyrotropin releasing hormone, substance P, methionine and leucine enkephalin) in the cervical spinal cord and other regions of the central nervous system of Wobbler mice by radioimmunoassays during several stages of the motoneuron disease compared w...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(92)90393-g

    authors： Yung KK,Tang F,Fielding R,Du YH,Vacca-Galloway LL

    更新日期：1992-09-01 00:00:00

  • Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons.

    abstract：:We have previously described a population of 5-hydroxytryptamine neurons which repetitively fires bursts of usually two (but occasionally three or four) action potentials, with a short (<20 ms) interspike interval within a regular low-frequency firing pattern. Here we used a paradigm of electrical stimulation comprisi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(00)00060-9

    authors： Gartside SE,Hajós-Korcsok E,Bagdy E,Hársing LG Jr,Sharp T,Hajós M

    更新日期：2000-01-01 00:00:00

  • Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus.

    abstract：:The circadian rhythms of mammals are generated by the circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Its intrinsic period is entrained to a 24 h cycle by external cues, mainly by light. Light impinging on the SCN at night causes either advancing or delaying phase shifts of the circad...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.01.016

    authors： Bendová Z,Sumová A,Mikkelsen JD

    更新日期：2009-03-17 00:00:00

  • Length summation of complex cells in cat striate cortex: a reappraisal of the "special/standard" classification.

    abstract：:A reappraisal of the relationship between length summation and receptive field length assessed by the minimum response field method, was made in complex cells recorded from the lightly anaesthetized feline striate cortex. This relationship has previously been proposed by Gilbert [(1977) J. Physiol., Lond. 268, 391-421...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(85)90065-x

    authors： Hammond P,Ahmed B

    更新日期：1985-07-01 00:00:00

  • Analysis of synaptic events in the mouse accessory olfactory bulb with current source-density techniques.

    abstract：:The accessory olfactory bulb of the mouse was studied by current source-density analysis of field potentials to determine the laminar and temporal distribution of synaptic currents evoked by electrical stimulation of the vomeronasal organ. The one-dimensional current source-density analysis revealed two major spatiall...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(92)90093-h

    authors： Kaba H,Keverne EB

    更新日期：1992-07-01 00:00:00

  • Intracellular protein kinase and calcium inward currents in perfused neurones of the snail Helix pomatia.

    abstract：:Changes in the amplitude of the calcium inward current caused by intracellular administration of tolbutamide (an inhibitor of the cyclic AMP-dependent protein kinase activity) or catalytic subunits of cAMP-dependent protein kinases from rabbit myocardium were studied on internally perfused nerve cells of the snail, He...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(84)90229-x

    authors： Doroshenko PA,Kostyuk PG,Martynyuk AE,Kursky MD,Vorobetz ZD

    更新日期：1984-01-01 00:00:00

  • Stimulation-mediated translocation of calmodulin and neurogranin from soma to dendrites of mouse hippocampal CA1 pyramidal neurons.

    abstract：:Calmodulin (CaM) and neurogranin (Ng) are two abundant neuronal proteins in the forebrain whose interactions are implicated in the enhancement of synaptic plasticity. To gain further insight into the actions of these two proteins we investigated whether they co-localize in principle neurons and whether they respond to...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.01.027

    authors： Huang KP,Huang FL,Shetty PK

    更新日期：2011-03-31 00:00:00

  • Entorhinal axons project to dentate gyrus in organotypic slice co-culture.

    abstract：:We have demonstrated the formation of entorhinodentate projections by axons arising from explants of embryonic mouse entorhinal cortex or slices of postnatal rat entorhinal area co-cultured in contact with slices of postnatal rat hippocampus in roller tube and static culture. Species-specific markers (Thy-1 alleles an...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(93)90530-s

    authors： Li D,Field PM,Starega U,Li Y,Raisman G

    更新日期：1993-02-01 00:00:00

  • Stress Adaptation Upregulates Oxytocin within Hypothalamo-Vagal Neurocircuits.

    abstract：:Stress plays a pivotal role in the development and/or exacerbation of functional gastrointestinal (GI) disorders. The paraventricular nucleus of the hypothalamus (PVN) contains neurons that are part of the hypothalamic-pituitary-adrenal axis as well as preautonomic neurons innervating, among other areas, gastric-proje...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2018.08.021

    authors： Jiang Y,Coleman FH,Kopenhaver Doheny K,Travagli RA

    更新日期：2018-10-15 00:00:00

  • Co-localization of neurotensin- and cholecystokinin-like immunoreactivities in catecholamine neurons in the rat dorsomedial medulla.

    abstract：:Co-localization of neurotensin and cholecystokinin in tyrosine hydroxylase-containing neurons in the nucleus tractus solitarius of the rat was demonstrated by immunocytochemistry with fluorescent double-staining combined with the peroxidase-antiperoxidase method. Co-localization of neurotensin/tyrosine hydroxylase or ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(88)90326-0

    authors： Kawai Y,Takagi H,Tohyama M

    更新日期：1988-01-01 00:00:00

  • NK1-tachykinin receptors and prolonged, stimulus-evoked alterations in the excitability of withdrawal reflexes in the decerebrated and spinalized rabbit.

    abstract：:Intense natural or electrical stimulation of afferents from the toes or the heel results in prolonged changes in the excitability of the heel withdrawal reflex pathway in the rabbit. This study has investigated the roles played by tachykinin NK1 receptors in mediating these effects. Reflexes were evoked by electrical ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)00608-8

    authors： Houghton AK,Clarke RW

    更新日期：1995-06-01 00:00:00

  • Stress and the developing adolescent brain.

    abstract：:Adolescence is a time of continued brain maturation, particularly in limbic and cortical regions, which undoubtedly plays a role in the physiological and emotional changes coincident with adolescence. An emerging line of research has indicated that stressors experienced during this crucial developmental stage may affe...

    journal_title：Neuroscience

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroscience.2012.10.048

    authors： Eiland L,Romeo RD

    更新日期：2013-09-26 00:00:00

  • Pharmacological characteristics and anatomical distribution of [3H]oxytocin-binding sites in the Wistar rat brain studied by autoradiography.

    abstract：:Oxytocin-binding sites were detected by autoradiography on rat brain sections incubated in the presence of the [3H]oxytocin. These sites were characterized pharmacologically using quantitative autoradiography. High pressure liquid chromatography controls of the incubation media indicated that labelling was due to the ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(87)90113-8

    authors： Freund-Mercier MJ,Stoeckel ME,Palacios JM,Pazos A,Reichhart JM,Porte A,Richard P

    更新日期：1987-02-01 00:00:00

  • Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis.

    abstract：:Sestrin2 (Sesn2) is a stress response protein which expresses neuroprotective characteristics in some neurodegenerative disorders. However, the impact of Sesn2 on the clinical outcome of stroke is unclear. The nuclear factor-erythroid 2 related factor 2/heme oxygenase-1 (Nrf2/HO-1) pathway is a key factor in angiogene...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2019.05.005

    authors： Wang P,Zhao Y,Li Y,Wu J,Yu S,Zhu J,Li L,Zhao Y

    更新日期：2019-07-01 00:00:00

  • The inhibitory effects of nicotinic antagonists on currents elicited by GABA in rat hippocampal neurons.

    abstract：:The nicotinic antagonists d-tubocurarine and trimethaphan camsylate competitively inhibit GABA-induced currents. Hexamethonium, mecamylamine and dihydro-beta-erythroidine, other nicotinic antagonists, do not affect GABA-elicited currents. The trimethaphan effect is completely reversed by a putative convulsant receptor...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(95)00011-7

    authors： Wotring VE,Yoon KW

    更新日期：1995-07-01 00:00:00

  • Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABA release from adult rat hippocampal and cortical slices.

    abstract：:Accumulated evidence suggests that the single transmembrane domain insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-II/M6P or IGF-II receptor) plays an important role in the intracellular trafficking of lysosomal enzymes and endocytosis-mediated degradation of insulin like growth factor (IGF-II). Howeve...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2010.07.026

    authors： Amritraj A,Rauw G,Baker GB,Kar S

    更新日期：2010-10-27 00:00:00

  • Sesamin suppresses activation of microglia and p44/42 MAPK pathway, which confers neuroprotection in rat intracerebral hemorrhage.

    abstract：:Thrombin plays important roles in the pathology of intracerebral hemorrhage (ICH). The recruitment of activated microglia, accompanied by thrombin-induced phosphorylation of the mitogen-activated protein kinase (MAPK) family, contributes to ICH-associated neuron loss. Here we investigated the possibility that sesamin,...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2012.11.057

    authors： Ohnishi M,Monda A,Takemoto R,Matsuoka Y,Kitamura C,Ohashi K,Shibuya H,Inoue A

    更新日期：2013-03-01 00:00:00

  • Investigation of a central nucleus of the amygdala/dorsal raphe nucleus serotonergic circuit implicated in fear-potentiated startle.

    abstract：:Serotonergic systems are thought to play an important role in control of motor activity and emotional states. We used a fear-potentiated startle paradigm to investigate the effects of a motor-eliciting stimulus in the presence or absence of induction of an acute fear state on serotonergic neurons in the dorsal raphe n...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.01.042

    authors： Spannuth BM,Hale MW,Evans AK,Lukkes JL,Campeau S,Lowry CA

    更新日期：2011-04-14 00:00:00

  • Intense cold noxious stimulation of the rat hindpaw induces c-fos expression in lumbar spinal cord neurons.

    abstract：:This study evaluated Fos-like immunoreactivity in lumbar spinal cord neurons following intense cold stimulation and then the modifications induced by opioid administration. Under urethane anaesthesia, the rat's right foot was stimulated by holding it in a regulated temperature bath at 15, 10, 0, -10, -15, -17.5 or -20...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)90609-2

    authors： Abbadie C,Honoré P,Besson JM

    更新日期：1994-03-01 00:00:00

  • Estrogen-dependent MicroRNA-504 Expression and Related Baroreflex Afferent Neuroexcitation via Negative Regulation on KCNMB4 and KCa1.1 β4-subunit Expression.

    abstract：:Large conductance of Ca2+-activated K+ channel (KCa1.1) plays an inhibitory role in neuroexcitation. However, the expression of KCNMB4/β4-subunit in the nodose ganglia (NG) and nucleus tractus solitarius (NTS), and its effect and regulation on baroreflex afferent function at post-transcriptional level of female rats r...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2020.07.003

    authors： Feng Y,Liu Y,Cao PX,Sun X,Li KX,Li XY,Liu L,Wang HD,Cui CP,Xiong X,Zhang HC,Qiao GF,Li BY

    更新日期：2020-08-21 00:00:00

  • Endothelins are extracellular signals modulating cytoskeletal actin organization in rat cultured astrocytes.

    abstract：:Effects of endothelin-3 on rapid morphological changes and cytoskeletal actin organization of rat cortical cultured astrocytes were examined. In serum-free medium, treatments with 1 mM dibutyryl cAMP and 5 microM cytochalasin B, an inhibitor of actin polymerization, caused astrocytic morphological changes with cytopla...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)90420-0

    authors： Koyama Y,Baba A

    更新日期：1994-08-01 00:00:00

  • Distribution of Fos-immunoreactive cells in rat forebrain and midbrain following social defeat stress and diazepam treatment.

    abstract：:The anxiolytic diazepam selectively inhibits psychological stress-induced autonomic and behavioral responses without causing noticeable suppression of other central performances. This pharmacological property of diazepam led us to the idea that neurons that exhibit diazepam-sensitive, psychological stress-induced acti...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2014.04.047

    authors： Lkhagvasuren B,Oka T,Nakamura Y,Hayashi H,Sudo N,Nakamura K

    更新日期：2014-07-11 00:00:00

  • Statistical models suggest presence of two distinct subpopulations of miniature EPSCs in fast-spiking interneurons of rat prefrontal cortex.

    abstract：:Properties of excitatory synaptic responses in fast-spiking interneurons (FSIs) and pyramidal neurons (PNs) are different; however, the mechanisms and determinants of this diversity have not been fully investigated. In the present study, voltage-clamp recording of miniature excitatory post-synaptic currents (mEPSCs) w...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.06.034

    authors： Malkin SL,Kim KK,Tikhonov DB,Magazanik LG,Zaitsev AV

    更新日期：2015-08-20 00:00:00

  • Effects of S100A1 and S100B on microtubule stability. An in vitro study using triton-cytoskeletons from astrocyte and myoblast cell lines.

    abstract：:S100A1 and S100B are members of a multigenic family of Ca(2+)-binding proteins of the EF-hand type highly abundant in astrocyte and striated muscle cells that have been implicated in the Ca(2+)-dependent regulation of several intracellular activities including the assembly and disassembly of microtubules and type III ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(00)00238-4

    authors： Sorci G,Agneletti AL,Donato R

    更新日期：2000-01-01 00:00:00

  • Cochlear protection from acoustic injury by inhibitors of p38 mitogen-activated protein kinase and sequestosome 1 stress protein.

    abstract：:This study evaluated the protective role of p38 mitogen-activated protein kinase (p38 MAPK) inhibitors and sequestosome 1 (Sqstm1/A170/p62), a stress-induced signal modulator, in acoustic injury of the cochlea in mice. Two weeks after the exposure of mice to acoustic stress, threshold shifts of the auditory brainstem ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.12.038

    authors： Tabuchi K,Oikawa K,Hoshino T,Nishimura B,Hayashi K,Yanagawa T,Warabi E,Ishii T,Tanaka S,Hara A

    更新日期：2010-03-17 00:00:00

  • Susceptibility and Resilience to PTSD-Like Symptoms in Mice Are Associated with Opposite Dendritic Changes in the Prelimbic and Infralimbic Cortices Following Trauma.

    abstract：:Post-traumatic stress disorder (PTSD) is triggered by exposure to traumatic events, but not everyone who experiences trauma develops this disorder. Like humans, PTSD-like symptoms develop in some laboratory rodents (susceptible individuals), while others express less or no symptoms (resilient individuals). Here, consi...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2019.08.018

    authors： Lguensat A,Bentefour Y,Bennis M,Ba-M'hamed S,Garcia R

    更新日期：2019-10-15 00:00:00

  • Simvastatin increases excitability in the hippocampus via a PI3 kinase-dependent mechanism.

    abstract：:Simvastatin is an HMG-CoA reductase inhibitor commonly used in the clinic to treat hypercholesterolemia. In addition, simvastatin has been shown to cross the blood-brain barrier and pleiotropic effects of simvastatin have been reported including anti-inflammatory properties, enhancement of neurite outgrowth, and memor...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.02.023

    authors： Métais C,Hughes B,Herron CE

    更新日期：2015-04-16 00:00:00

  • Transient populations of presumptive macrophages in the brain of the developing hamster, as indicated by endocytosis of blood-borne horseradish peroxidase.

    abstract：:During postnatal development, clusters of cells associated with the mononuclear phagocytic system appear within the white matter of rodents and cats. We studied the distribution and morphology of these cells in the hamster's brain during the first 2 weeks after birth. In animals of different ages, horseradish peroxida...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(85)90263-5

    authors： Lent R,Linden R,Cavalcante LA

    更新日期：1985-08-01 00:00:00