Giardia lamblia -- a model organism for eukaryotic cell differentiation.

Abstract:

:Giardia lamblia is a binucleated, flagellated protozoan parasite that inhabits the upper small intestine of its vertebrate hosts. The entire life cycle, which can be completed in vitro, is simple with cycling between a vegetative trophozoite and a highly resistant cystic form. The parasite is one of the earliest diverging eukaryotes known and more than 95% of the genome is sequenced. This makes Giardia an excellent model system for studies of basic eukaryotic processes like cell differentiation. In this review we will discuss recent data concerning Giardia differentiation with a focus on DNA replication and cytokinesis.

journal_name

FEMS Microbiol Lett

authors

Svärd SG,Hagblom P,Palm JE

doi

10.1111/j.1574-6968.2003.tb11490.x

keywords:

subject

Has Abstract

pub_date

2003-01-21 00:00:00

pages

3-7

issue

1

eissn

0378-1097

issn

1574-6968

pii

S0378109702011072

journal_volume

218

pub_type

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