Abstract:
:The rather shallow growth of click-evoked otoacoustic emissions (CEOAE) with click intensity, namely <1 dB/dB, distinguishes genuine CEOAEs from stimulus artifacts, thereby providing the rationale for the popular 'derived nonlinear recording' method. However, other CEOAE nonlinearities regarding phase or envelope dependence on stimulus intensity have been barely acknowledged so far. The present work used CEOAEs from 20 normal ears recorded in response to 50-86 dB peak equivalent SPL clicks. The phases of CEOAE spectral components varied considerably with click intensity (sometimes more than 120 degrees ), mostly in a monotonic manner and in such a way that in the majority of ears, phase lagged with increasing intensity. When present, synchronized spontaneous otoacoustic emissions exhibited the same behavior. In a few instances, conspicuous frequency shifts of CEOAE spectral peaks were seen. In contrast to CEOAE phases, envelopes were almost intensity-invariant. This behavior contrasts with that of basilar membrane motion at the place tuned to the stimulus frequency, as consistently disclosed by several recent publications, i.e., no phase shift and large envelope shift with stimulus intensity. It is thought that the phase invariance of basilar membrane motion implies that whatever they do, outer hair cells cannot alter the resonance frequency of the cochlear partition. If one elaborates along this line of reasoning, the large phase shift of CEOAEs with click intensity implies that CEOAEs at frequency f cannot come from the place tuned to f and that instead, they may be intermodulation distortion products produced by nonlinear interactions between spectral components of the click stimulus over a significant length of the basilar membrane.
journal_name
Hear Resjournal_title
Hearing researchauthors
Carvalho S,Büki B,Bonfils P,Avan Pdoi
10.1016/s0378-5955(02)00745-1keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
215-25issue
1-2eissn
0378-5955issn
1878-5891pii
S0378595502007451journal_volume
175pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract::The frequency-modulation following response (FMFR) is a steady-state evoked response which may be a neural correlate of frequency discrimination. Aged subjects with normal hearing have abnormal frequency discrimination for low carrier frequencies and thus it might be predicted that aged individuals would have reduced ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(01)00398-7
更新日期:2002-03-01 00:00:00
abstract::A model is introduced for auditory adaptation based on the stochastic models that are widely documented for birth and death processes and used as a vehicle to review single unit and compound action potential studies as well as various models for adaptation and forward masking. It appears that such a model inherently i...
journal_title:Hearing research
pub_type: 杂志文章,评审
doi:10.1016/0378-5955(85)90110-8
更新日期:1985-04-01 00:00:00
abstract::The human auditory system is comprised of specialized but interacting anatomic and functional pathways encoding object, spatial, and temporal information. We review how learning-induced plasticity manifests along these pathways and to what extent there are common mechanisms subserving such plasticity. A first series o...
journal_title:Hearing research
pub_type: 杂志文章,评审
doi:10.1016/j.heares.2010.03.086
更新日期:2011-01-01 00:00:00
abstract::Peripheral auditory adaptation has been studied extensively in animal models, and multiple exponential components have been identified. This study explores the feasibility of estimating these component processes for human listeners with a peripheral model of adaptation. The processes were estimated from off-frequency ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(01)00428-2
更新日期:2002-02-01 00:00:00
abstract::The density of cochlear inner hair cells in Wistar rats is greatest on a short section of the basilar membrane about a fifth of its length from the base. This place corresponds to the frequency region of 30--40 kHz which is supposed to be the region of best hearing. ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(80)90010-6
更新日期:1980-07-01 00:00:00
abstract::Although most birds encounter large pressure variations during flight, motion of the middle ear components as a result of changing ambient pressure are not well known or described. In the present study, motion of the columella footplate and tympanic membrane (extrastapedius) in domestic chickens (Gallus gallus domesti...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2018.05.012
更新日期:2018-08-01 00:00:00
abstract::The effect of glutathione co-therapy on the expression of gentamicin ototoxicity was tested in pigmented guinea pigs. The first group of animals was injected with gentamicin (100 mg/kg body weight/day) for two weeks followed by 10 weeks of rest. A second group received glutathione by gastric gavage immediately prior t...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(94)90255-0
更新日期:1994-06-15 00:00:00
abstract::Validity of the neurophysiological model of tinnitus (Jastreboff, 1990), outlined in this paper, was tested on data from multicenter trial of tinnitus masking (Hazell et al., 1985). Minimal masking level, intensity match of tinnitus, and the threshold of hearing have been evaluated on a total of 382 patients before an...
journal_title:Hearing research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0378-5955(94)90113-9
更新日期:1994-11-01 00:00:00
abstract::Guinea pigs were exposed to a 10 kHz pure tone and damage to the cochlea was investigated immediately after exposure, or after a recovery period ranging from 18-25 days. Structural damage was assessed using scanning electron microscopy and functional damage estimated using the N1 threshold audiogram. Exposure at 106 d...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(80)90015-5
更新日期:1980-01-01 00:00:00
abstract::No adequate theory for the signal-transmission properties of the peripheral auditory system exists for any vertebrate ear. Because the mammalian ear seems to pose conceptual and technical problems that complicate the development of an adequate theory, it is worthwhile to investigate simpler ears. The ear of the alliga...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(85)90164-9
更新日期:1985-01-01 00:00:00
abstract::The standard procedure to study temporal encoding of sound waveforms in the auditory system has been Fourier analysis of responses to periodic stimuli. We introduce a new metric--correlation index (CI)--which is based on a simple counting of spike coincidences. It can be used for responses to aperiodic stimuli and doe...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2006.03.010
更新日期:2006-06-01 00:00:00
abstract::Cochlear compression in normal-hearing listeners was estimated at octave frequencies from 250 to 4000 Hz using a forward-masking paradigm. Temporal masking curves (TMCs) for a 10-dB SL signal were obtained with two maskers -- one equal in frequency to the signal and another an octave below the signal. The ratio of the...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2004.10.006
更新日期:2005-03-01 00:00:00
abstract::Some important relationships between two auditory nonlinearities, unmasking and combination tone (CT) production, are described. An example of unmasking is provided by using a forward-masking paradigm where a baseline is first obtained by determining the threshold of a 2000 Hz signal preceded by a 2000 Hz masker. When...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(80)90070-2
更新日期:1980-06-01 00:00:00
abstract::Gamma-aminobutyric acid (GABA)-like immunoreactivity in the chick basilar papilla and lagenar macula was studied by using anti-serum against GABA coupled with glutaraldehyde to bovine serum albumin. GABA-like immunoreactivity was localized selectively in the cytoplasm of both tall and short hair cells in the basilar p...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(87)90178-x
更新日期:1987-01-01 00:00:00
abstract::This paper reports hourly and daily monitoring of the frequencies of spontaneous otoacoustic emissions. Regular circadian variations in frequency were found in two of three subjects. Consistent monthly variations, in step with the menstrual cycle, were seen in three of four women. The circadian cycle typically showed ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(92)90012-c
更新日期:1992-02-01 00:00:00
abstract::A three-dimensional computer simulation of the experiment (Benser M. E., Issa N.P., Hudspeth A.J., 1993. Hear. Res. 68, 243-252), devoted to the mechanical stimulation of the surface of saccular membrane of bullfrog with the otoconial mass removed was carried out by finite-element method. Comparison of the calculated ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(00)00034-4
更新日期:2000-05-01 00:00:00
abstract::Cochlear implant insertion should be as least traumatic as possible in order to reduce trauma to the cochlear sensory structures. The force applied to the cochlea during array insertion should be controlled to limit insertion-related damage. The relationship between insertion force and histological traumatism remains ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2016.11.002
更新日期:2017-02-01 00:00:00
abstract::Previous investigations have shown that a subset of inferior colliculus neurons, which have been designated type O units, respond selectively to isolated features of the cat's head-related transfer functions (HRTFs: the directional transformation of a free-field sound as it propagates from the head to the eardrum). Ba...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2008.01.008
更新日期:2008-04-01 00:00:00
abstract::An investigation of the effects of the level and bandwidth of the masking noise and of the effect of test-tone duration on binaural masking-level differences (BMLDs) has been carried out using the standard Békésy audiometric techniques. The BMLDs increase in magnitude with increasing masker level, reach a shallow maxi...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(84)90015-7
更新日期:1984-05-01 00:00:00
abstract::Immunolabeling of heregulin, a growth factor that enhances cell proliferation in damaged utricles, and one of its binding receptors, ErbB-2, has been briefly described in the P3 rat cochlea and utricle [Zheng et al. (1999) J. Neurocytol. 28, 901-912]. However, little is known about the distribution of heregulin and it...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(02)00339-8
更新日期:2002-07-01 00:00:00
abstract::The compound action potential (CAP) and the auditory brainstem response (ABR; waves ii and iv) were recorded in young (4-8 month) and aged (33-37 month) gerbils using a paradigm similar to that used in some psychophysical studies of gap detection (a pair of identical low-pass noises separated by a silent gap). Respons...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(96)90016-7
更新日期:1996-12-01 00:00:00
abstract::Auditory-nerve excitation by two response factors that can be in antiphase has been hypothesized by Kiang (1990) on the basis of non-linear interference in responses to tones (Kiang et al., 1969). The general conditions for antiphasic responses and the relevance of the hypothesis for other auditory stimuli are unknown...
journal_title:Hearing research
pub_type: 杂志文章,评审
doi:10.1016/0378-5955(95)00154-7
更新日期:1995-10-01 00:00:00
abstract::Gerbils are frequently used in auditory research; however, only limited information on the exact frequency representation in the cochlea is available. Therefore the place-frequency map of the gerbil was determined by iontophoretic application of horseradish peroxidase in physiologically characterized single auditory n...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(95)00230-8
更新日期:1996-05-01 00:00:00
abstract::To investigate the audio-vocal feedback responses of (F0) to hearing amplification in severe-to-profound prelingual hearing loss (SPHL) using power spectral analysis of F0 contour of sustained vowels. Sustained phonations of vowel/a/of seventeen participants with SPHL were acquired with and without hearing-aid amplifi...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2013.04.010
更新日期:2013-08-01 00:00:00
abstract::The ubiquity of social vocalizations among animals provides the opportunity to identify conserved mechanisms of auditory processing that subserve communication. Identifying auditory coding properties that are shared across vocal communicators will provide insight into how human auditory processing leads to speech perc...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2013.05.005
更新日期:2013-11-01 00:00:00
abstract::Units in the auditory cortex of cats respond to a large variety of stimuli: pure tones, AM- and FM-modulated signals, clicks, wideband noise, natural sounds, and more. However, no single family of sounds was found to be optimal (in the sense that oriented lines are optimal in the visual cortex). The search for optimal...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(94)90222-4
更新日期:1994-01-01 00:00:00
abstract::Human behavioral thresholds for trains of biphasic pulses applied to a single channel of Nucleus CI24 and LAURA cochlear implants were measured as a function of inter-phase gap (IPG). Experiment 1 used bipolar stimulation, a 100-pps pulse rate, and a 400-ms stimulus duration. In one condition, the two phases of each p...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2005.03.021
更新日期:2005-07-01 00:00:00
abstract::A model for cochlear mechanics is proposed to take account of its two systems, one passive and one active. The classical passive system stimulates the inner hair cells directly at levels above about 40 dB SL. At intensities below about 60 dB an active process, the 'cochlear amplifier' (CA), somehow provides additional...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(83)90136-3
更新日期:1983-01-01 00:00:00
abstract::In a previous study, we have demonstrated the presence of two adenosine receptor (AR) subtypes, namely A1 and A3AR, in the chinchilla cochlea. One or both of these receptors couple to activation of antioxidant enzymes, with resulting decreases in lipid peroxidation. The chemotherapeutic agent, cisplatin, was shown to ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(97)00103-2
更新日期:1997-09-01 00:00:00
abstract::Within auditory pathways, the intrinsic electrical properties of neurons, and in particular their complement of potassium channels, play a key role in shaping the timing and pattern of action potentials produced by sound stimuli. The Kv9.1 gene encodes a potassium channel alpha subunit that is expressed in a variety o...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(00)00117-9
更新日期:2000-09-01 00:00:00