A model for signal transmission in an ear having hair cells with free-standing stereocilia. I. Empirical basis for model structure.

abstract：:Eighth nerve endings and neuronal types in the nucleus magnocellularis were analyzed in the red-eared turtle (Chrysemys scripta elegans). One group of turtles had horseradish peroxidase (HRP) injected into the surgically exposed inner ear. Following injection the animals survived for 3-5 days and then their 8th nerve ...

journal_title：Hearing research

authors： Browner RH,Marbey D

更新日期：1988-06-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Hearing research

authors： Brownell WE

更新日期：2009-10-07 00:00:00

abstract：:The intra-cochlear distributions of aspartate aminotransferase and glutaminase, prominent enzymes of aspartate and glutamate metabolism, have been studied by quantitative microchemical techniques. Also measured was choline acetyltransferase, the enzyme synthesizing acetylcholine, and a marker for the olivocochlear bun...

journal_title：Hearing research

authors： Wiet GJ,Godfrey DA,Ross CD,Dunn JD

更新日期：1986-01-01 00:00:00

abstract：:Cochlear implant (CI) users typically have excellent speech recognition in quiet but struggle with understanding speech in noise. It is thought that broad current spread from stimulating electrodes causes adjacent electrodes to activate overlapping populations of neurons which results in interactions across adjacent c...

journal_title：Hearing research

authors： Srinivasan AG,Padilla M,Shannon RV,Landsberger DM

更新日期：2013-05-01 00:00:00

abstract：:Noise over-stimulation will induce or influence molecular pathways in the cochlea; one approach to the identification of the components of these pathways in the cochlea is to examine genes and proteins that change following different types and levels of stress. Quantitative reverse transcription polymerase chain react...

journal_title：Hearing research

authors： Caravelli A,Pianese L,Saulino C,Di Leva F,Sequino L,Cocozza S,Marciano E,Franzé A

更新日期：2004-12-01 00:00:00

abstract：:The ear of the goldfish (Carassius auratus) contains three otolithic endorgans: the saccule, lagena, and utricle. The saccule has an auditory function in most teleost fishes for whom data are available, and there is evidence that the lagena is also an auditory endorgan in the goldfish. This study was conducted to comp...

journal_title：Hearing research

authors： Edds-Walton PL,Popper AN

更新日期：2000-03-01 00:00:00

abstract：:The central nucleus of the inferior colliculus (CNIC) contains different types of neurons and is a source of ascending projection to the medial geniculate body (MGB), commissural projection to the contralateral IC, direct descending projection to the cochlea nucleus (CN) and indirect projection to the CN via the super...

journal_title：Hearing research

authors： Okoyama S,Ohbayashi M,Ito M,Harada S

更新日期：2006-08-01 00:00:00

abstract：:Furosemide is a loop diuretic which is ototoxic. Investigations have shown the stria vascularis to be the target tissue of this ototoxic drug. The purpose of the present study was to investigate the effects of furosemide on the stria vascularis in chinchillas, in controls and in animals pretreated with the above organ...

journal_title：Hearing research

authors： Rybak LP,Whitworth C,Weberg A,Scott V

更新日期：1992-04-01 00:00:00

abstract：:Dominant white spotting W/W(v) and W(v)/W(v) mice are well-known mutants that lack strial intermediate cells in their cochlea and manifest hereditary sensorineural hearing loss. We recently reported marked thickening of and IgG deposition on the basement membrane of strial capillaries in W/W(v) mutant mice, similar to...

journal_title：Hearing research

authors： Fujimura T,Suzuki H,Shimizu T,Tokui N,Kitamura T,Udaka T,Doi Y

更新日期：2005-11-01 00:00:00

abstract：:The primary goal of most cochlear implant procedures is to improve a patient's ability to discriminate speech. To accomplish this, cochlear implants are programmed so as to maximize speech understanding. However, programming a cochlear implant can be an iterative, labor-intensive process that takes place over months. ...

journal_title：Hearing research

authors： Pollonini L,Olds C,Abaya H,Bortfeld H,Beauchamp MS,Oghalai JS

更新日期：2014-03-01 00:00:00

abstract：:In order to determine the place-frequency map of the rat cochlea, iontophoretic HRP-injections were made into the cochlear nucleus at electrophysiologically characterized positions. Distribution of retrograde HRP transport in cochlear spiral ganglion cells was analysed by means of a three dimensional reconstruction of...

journal_title：Hearing research

authors： Müller M

更新日期：1991-02-01 00:00:00

abstract：:The basilar papilla length increases systematically with body mass for 41 species from more than 10 avian orders and this relation does not differ between phylogenetic groups. Audiograms of 25 non-strigiform and 12 owl species, normalized relative to best frequency and best threshold, were used to compare audiogram sh...

journal_title：Hearing research

authors： Gleich O,Langemann U

更新日期：2011-03-01 00:00:00

abstract：:We confirm the report of Mountain (Mountain, D.C. (1980): Science 210, 77-72) that stimulating the crossed olivocochlear bundle (COCB) can change the magnitude of the distortion product (f2-f1) in the ear-canal sound pressure. Our results are extended to include (2f1-f2) as well as (f2-f1) from anesthetized chinchilla...

journal_title：Hearing research

authors： Siegel JH,Kim DO

更新日期：1982-02-01 00:00:00

abstract：:It is widely appreciated that the key predictor of the pitch of a sound is its periodicity. Neural structures which support pitch perception must therefore be able to reflect the repetition rate of a sound, but this alone is not sufficient. Since pitch is a psychoacoustic property, a putative cortical code for pitch m...

journal_title：Hearing research

authors： Walker KM,Bizley JK,King AJ,Schnupp JW

更新日期：2011-01-01 00:00:00

abstract：:Over the last 30 years a wide range of manipulations of auditory input and experience have been shown to result in plasticity in auditory cortical and subcortical structures. The time course of plasticity ranges from very rapid stimulus-specific adaptation to longer-term changes associated with, for example, partial h...

journal_title：Hearing research

authors： Irvine DRF

更新日期：2018-05-01 00:00:00

abstract：:Drugs of the salicylate family (aspirin-like drugs) are reversibly ototoxic. Electrophysiologic and ultrastructural evidence suggests an impairment of the sensory hair cells of the cochlea following salicylate treatment. In addition, since these drugs can cause vasoconstriction, the ototoxicity of salicylates may also...

journal_title：Hearing research

authors： Didier A,Miller JM,Nuttall AL

更新日期：1993-09-01 00:00:00

abstract：:In order to clarify the otoconia formation and turnover, tetracycline, an antibiotic that precipitates at calcifying fronts and serves as a fluorescent marker, was injected into eggs at different stages of chick embryonic development, as well as into postnatal chicken and into adult animals. The changes in the intensi...

journal_title：Hearing research

authors： Balsamo G,Avallone B,Del Genio F,Trapani S,Marmo F

更新日期：2000-10-01 00:00:00

abstract：:Recently, many lines of evidence have supported the possibilities that vasopressin (VP) is closely linked to the formation of endolymphatic hydrops in Meniere's disease. In the present study, it was examined whether or not the chronic administration of VP might induce endolymphatic hydrops. For this purpose, histologi...

journal_title：Hearing research

authors： Takeda T,Takeda S,Kitano H,Okada T,Kakigi A

更新日期：2000-02-01 00:00:00

abstract：:Behavioral studies on complex sound perception in goldfish were carried out in order to help determine what, if any, differences exist between the sense of hearing of fishes and other vertebrates. A stimulus generalization paradigm was used with classical conditioning in three experiments to determine: (1) the percept...

journal_title：Hearing research

authors： Fay RR

更新日期：1995-09-01 00:00:00

abstract：:The tympanic membrane is a key component of the human auditory apparatus. Good estimates of tympanic membrane mechanical properties are important to obtain realistic models of middle ear mechanics. Current literature values are almost all derived from direct mechanical tests on cut-out strips. For a biomedical specime...

journal_title：Hearing research

authors： Aernouts J,Aerts JR,Dirckx JJ

更新日期：2012-08-01 00:00:00

abstract：:When using bone vibrator transducers for clinical measurements, the transfer of energy from the bone driver depends on the impedance match between the driver and the load (human mastoid or otherwise) to which the driver will be applied. Current clinical calibration methods are incapable of quantifying this impedance m...

journal_title：Hearing research

authors： Weece R,Allen J

更新日期：2010-05-01 00:00:00

abstract：:Effects of stimulus level on discrimination of one stimulation site from another were examined in 15 human subjects with Nucleus-22 cochlear implant systems. Bipolar stimulation was used in all cases with electrodes in the bipolar pair separated by 1.5 mm (center to center). Subjects were first tested at a medium loud...

journal_title：Hearing research

authors： Pfingst BE,Holloway LA,Zwolan TA,Collins LM

更新日期：1999-08-01 00:00:00

abstract：:The role of glycine and GABA as inhibitory neurotransmitters in the adult vertebrate nervous system has been well characterized in a variety of model systems, including the auditory, which is particularly well suited for analyzing inhibitory neurotransmission. However, a full understanding of glycinergic and GABAergic...

journal_title：Hearing research

authors： Friauf E,Rust MB,Schulenborg T,Hirtz JJ

更新日期：2011-09-01 00:00:00

abstract：:The ability of auditory-nerve (AN) fibers to encode modulation frequencies, as characterized by temporal modulation transfer functions (TMTFs), generally shows a low-pass shape with a cut-off frequency that increases with fiber characteristic frequency (CF). Because AN-fiber bandwidth increases with CF, this result ha...

journal_title：Hearing research

authors： Kale S,Heinz MG

更新日期：2012-04-01 00:00:00

abstract：:Transtympanic administration of gentamicin is a widely accepted and effective approach for treating patients with intractable vertigo. Previous studies have demonstrated the uptake, distribution and effects of gentamicin in peripheral vestibular and cochlear structures after transtympanic injection. However, little is...

journal_title：Hearing research

authors： Zhang YB,Zhang R,Zhang WF,Steyger PS,Dai CF

更新日期：2012-01-01 00:00:00

abstract：:Heat shock protein-27 (Hsp27) is known to function as both a stress-inducible molecular chaperone and regulator of actin polymerization. For many cells in the cochlea, actin is part of the cytoskeleton and plays an important role in the maintenance of cochlear function. To understand the molecular processes by which t...

journal_title：Hearing research

authors： Leonova EV,Fairfield DA,Lomax MI,Altschuler RA

更新日期：2002-01-01 00:00:00

abstract：:Biochemical and pharmacological evidence support a role for nitric oxide (NO) and glutathione (GSH) in the cochlea. GSH combines with NO in tissue to form nitrosoglutathione (GSNO) that can act as a storage form for GSH and NO. Therefore, we tested GSNO on sound-evoked responses of the cochlea (cochlear microphonic, C...

journal_title：Hearing research

authors： Nenov AP,Skellett RA,Fallon M,Bobbin RP

更新日期：1997-08-01 00:00:00

abstract：:Songbirds spend much of their time learning, producing, and listening to complex vocal sequences we call songs. Songs are learned via cultural transmission, and singing, usually by males, has a strong impact on the behavioral state of the listeners, often promoting affiliation, pair bonding, or aggression. What is it ...

journal_title：Hearing research

authors： Rothenberg D,Roeske TC,Voss HU,Naguib M,Tchernichovski O

更新日期：2014-02-01 00:00:00

abstract：:Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated eleme...

journal_title：Hearing research

authors： McCreery D,Yadev K,Han M

更新日期：2018-06-01 00:00:00

abstract：:One can construct narrow bands of noise that contain delays of either the envelope, the phase, or the carrier separately or in combination. Delayed and undelayed noises will have identical spectra if, and only if, both the envelope and the phase undergo delays of the same magnitude. To study lateralization of these si...

journal_title：Hearing research

authors： Amenta CA 3rd,Trahiotis C,Bernstein LR,Nuetzel JM

更新日期：1987-01-01 00:00:00