The role of broadband inhibition in the rate representation of spectral cues for sound localization in the inferior colliculus.

Abstract:

:Previous investigations have shown that a subset of inferior colliculus neurons, which have been designated type O units, respond selectively to isolated features of the cat's head-related transfer functions (HRTFs: the directional transformation of a free-field sound as it propagates from the head to the eardrum). Based on those results, it was hypothesized that type O units would show enhanced spatial tuning in a virtual sound field that conveyed the full complement of HRTF-based localization cues. As anticipated, a number of neurons produced representations of virtual sound source locations that were spatially tuned, level tolerant, and effective under monaural conditions. Preferred locations were associated with spectral cues that complemented the highly individualized broadband inhibitory patterns of tuned neurons. That is, higher response magnitudes were achieved when spectral peaks coincided with excitatory influences at best frequency (BF: the most sensitive frequency) and spectral notches fell within flanking inhibitory regions. The directionally dependent modulation of narrowband ON-BF excitation by broadband OFF-BF inhibition was not a unique property of type O units.

journal_name

Hear Res

journal_title

Hearing research

authors

May BJ,Anderson M,Roos M

doi

10.1016/j.heares.2008.01.008

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

77-93

issue

1-2

eissn

0378-5955

issn

1878-5891

pii

S0378-5955(08)00005-1

journal_volume

238

pub_type

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