Correlation between the hair cell density and the auditory threshold in the white rat.

abstract：:The acoustic input-admittance at the alligator lizard's tympanic membrane varies with stimulus level; the magnitude of the variation can be as much as a factor of three. At 1.6 kHz, the frequency of maximum admittance magnitude, the admittance varies when the stimulus level exceeds 65 dB SPL. At frequencies above or b...

journal_title：Hearing research

authors： Rosowski JJ,Peake WT,Lynch TJ 3rd

更新日期：1984-12-01 00:00:00

abstract：:The vibration characteristics (amplitude and phase as a function of frequency) of the tympanic membrane in the grass frog were measured using a laser-doppler velocity meter. It was tested to what extent the frog's acoustic system behaves as a pressure gradient receiver. This might clarify how the frog localizes sound....

journal_title：Hearing research

authors： Vlaming MS,Aertsen AM,Epping WJ

更新日期：1984-05-01 00:00:00

abstract：:In a wide variety of mammals, the rim of the tympanic membrane (annulus fibrosus) has an array of contractile elements, either smooth muscle [Henson and Henson, J. Assoc. Res. Otolaryngol. 1 (2000) 25-32] or myofibroblasts [Kuijpers et al., Hear. Res. 128 (1999) 80-88]. These elements are anchored peripherally to the ...

journal_title：Hearing research

authors： Yang X,Henson OW Jr

更新日期：2002-02-01 00:00:00

abstract：:Recent studies have shown that the vestibular and auditory systems of some species of birds have the capacity to generate sensory hair cells postnatally. We used a traditional technique, 3H-thymidine autoradiography, and a newer method, bromodeoxyuridine immunocytochemistry, to determine whether ongoing proliferation ...

journal_title：Hearing research

authors： Roberson DF,Weisleder P,Bohrer PS,Rubel EW

更新日期：1992-01-01 00:00:00

abstract：:Kanamycin ototoxicity, combined with behavioral audiometry to evaluate threshold shifts, was used to destroy outer hair cells (OHCs) in the basal cochlea of the chincilla while leaving the inner hair cell (IHC) population largely intact. After survival times of four weeks to one year, transmission electron microscopy ...

journal_title：Hearing research

authors： Ryan AF,Woolf NK,Bone RC

更新日期：1980-12-01 00:00:00

abstract：:Alterations in the distribution and activity of Na,K-ATPase have been implicated in declining cell function with age. However, the location, size and anatomical complexity of the cochlea have limited study of this essential enzyme. Here we describe a micro-colorimetric assay which measures Na,K-ATPase activity in subr...

journal_title：Hearing research

authors： Gratton MA,Smyth BJ,Schulte BA,Vincent DA Jr

更新日期：1995-03-01 00:00:00

abstract：:A small, acidic Ca(2+)-binding protein (CBP-15) was recently detected in extracts of the mammalian auditory receptor organ, the organ of Corti [Senarita et al. (1995) Hear. Res. 90, 169-175]. N-terminal sequence data for CBP-15 [Thalmann et al. (1995) Biochem. Biophys. Res. Commun. 215, 142-147] implied membership in ...

journal_title：Hearing research

authors： Henzl MT,Shibasaki O,Comegys TH,Thalmann I,Thalmann R

更新日期：1997-04-01 00:00:00

abstract：:Studies in several mammalian species have demonstrated that auditory cortical neurons respond strongly to single frequency-modulated (FM) sweeps, and that most responses are selective for sweep direction and/or rate. In the present study, we used extracellular recordings to examine how neurons in the auditory cortices...

journal_title：Hearing research

authors： Orduña I,Mercado E 3rd,Gluck MA,Merzenich MM

更新日期：2001-10-01 00:00:00

abstract：:Periodicity coding was studied in primary auditory cortex of the ketamine anesthetized cat by simultaneously recording with two electrodes from up to 6 neural units in response to one second long click trains presented once per 3 s. Trains with click rates of 1, 2, 4, 8, 16 and 32/s were used and the responses of the ...

journal_title：Hearing research

authors： Eggermont JJ

更新日期：1991-11-01 00:00:00

abstract：:In mammals, the cochlear sensory epithelium becomes quiescent early during development. After the first postnatal week, there is no cell replacement or proliferation, and severe damage leads to permanent deafness. Supporting cells' trans-differentiation has been suggested as a way to regenerate cochlear hair cells aft...

journal_title：Hearing research

authors： Silva SA,Maass JC

更新日期：2019-03-01 00:00:00

abstract：:The scalp distributions of middle latency auditory evoked potentials (MAEPs) elicited by tone bursts of 250 and 4000 Hz were compared in two experiments. Na (19.9 ms), Pa (29.8 ms), and Pb (51.4 ms) components elicited by tones of either frequency had fronto-central distributions, whereas the Nb component (38.4 ms) wa...

journal_title：Hearing research

authors： Woods DL,Alain C,Covarrubias D,Zaidel O

更新日期：1995-05-01 00:00:00

abstract：:Previous studies have shown that objective measures based on stimulation with low-rate pulse trains fail to predict the threshold levels of cochlear implant (CI) users for high-rate pulse trains, as used in clinical devices. Electrically evoked auditory steady-state responses (EASSRs) can be elicited by modulated high...

journal_title：Hearing research

authors： Gransier R,Deprez H,Hofmann M,Moonen M,van Wieringen A,Wouters J

更新日期：2016-05-01 00:00:00

abstract：:Thresholds of neurons to sounds were compared as a function of central auditory structure [ventral cochlear nucleus (VCN), dorsal cochlear nucleus (DCN), and inferior colliculus (IC)] in young and middle-aged C57BL/6J mice (multiple- and single-unit recordings) and in young and old CBA/J mice (single-unit recordings)....

journal_title：Hearing research

authors： Willott JF,Parham K,Hunter KP

更新日期：1991-05-01 00:00:00

abstract：:The Frequency-Following Response (FFR) is a neurophonic auditory evoked potential that reflects the efficient encoding of speech sounds and is disrupted in a range of speech and language disorders. This raises the possibility to use it as a potential biomarker for literacy impairment. However, reference values for com...

journal_title：Hearing research

authors： Ribas-Prats T,Almeida L,Costa-Faidella J,Plana M,Corral MJ,Gómez-Roig MD,Escera C

更新日期：2019-01-01 00:00:00

abstract：:One objective electrophysiological test for deafness involves presenting a brief acoustic stimulus to a subject and measuring the electrical activity evoked in the muscle located just behind the ear (the post-auricular muscle or PAM). Although this electrical response has been known for many years, it has been ignored...

journal_title：Hearing research

authors： O'Beirne GA,Patuzzi RB

更新日期：1999-12-01 00:00:00

abstract：:Electrically evoked compound action potentials (ECAPs) have been used to examine temporal response patterns of the auditory nerve in cochlear implant (CI) recipients. ECAP responses to individual pulses in a pulse train vary across stimulation rates for individual CI users. For very slow rates, auditory neurons have a...

journal_title：Hearing research

authors： Hughes ML,Laurello SA

更新日期：2017-08-01 00:00:00

abstract：:Auditory brainstem responses (ABR) to clicks and noise bursts of various frequency bands and intensities were recorded in two bottlenosed dolphins, Tursiops truncatus. The purpose was to assess contributions of various parts of the cochlear partition to ABR and travelling wave velocity in the cochlea. At band-pass fil...

journal_title：Hearing research

authors： Popov VV,Supin AY

更新日期：2001-01-01 00:00:00

abstract：:Certain characteristics of the extracellular cochlear microphonic (CM) recorded by intracochlear electrodes change in a bimodal manner as a function of prior acoustic exposure, intensity of stimulation, or stimulus frequency. In the present study, it is shown that biasing the basilar membrane position toward scala tym...

journal_title：Hearing research

authors： Pierson M,Møller A

更新日期：1980-03-01 00:00:00

abstract：:The IgG1 mouse monoclonal antibody (MAb) KHRI-3, binds to an antigen of 65-68 kDa expressed on inner ear supporting cells in guinea pigs. We previously showed [Nair et al. (1995) Monoclonal antibody induced hearing loss. Hear. Res. 83, 101-113] that mice carrying the KHRI-3 hybridoma develop high frequency hearing los...

journal_title：Hearing research

authors： Nair TS,Prieskorn DM,Miller JM,Mori A,Gray J,Carey TE

更新日期：1997-05-01 00:00:00

abstract：:The ear of the goldfish (Carassius auratus) contains three otolithic endorgans: the saccule, lagena, and utricle. The saccule has an auditory function in most teleost fishes for whom data are available, and there is evidence that the lagena is also an auditory endorgan in the goldfish. This study was conducted to comp...

journal_title：Hearing research

authors： Edds-Walton PL,Popper AN

更新日期：2000-03-01 00:00:00

abstract：:In our companion paper (Le Calvez et al., 1998), the levels of distortion product otoacoustic emissions (DPOAE) were collected in the ears of CD1 mice with progressive degeneration of cochlear outer hair cells (OHC). Their comparison to standard functional measurements such as auditory-evoked brainstem responses (ABR)...

journal_title：Hearing research

authors： Le Calvez S,Guilhaume A,Romand R,Aran JM,Avan P

更新日期：1998-06-01 00:00:00

abstract：:Gross electrical responses to tone bursts were measured in the guinea pig with electrodes located in scala tympani (ST) and scala vestibuli (SV) of the cochlea, on the central portion of the VIIIth nerve fibres in the internal auditory meatus, and on the surface of the cochlear nuclear complex (CN). Intracochlear perf...

journal_title：Hearing research

authors： Sellick P,Patuzzi R,Robertson D

更新日期：2003-02-01 00:00:00

abstract：:Normal-hearing listeners can perceptually segregate concurrent sound sources, but listeners with significant hearing loss or who wear a cochlear implant (CI) lag behind in this ability. Perceptual grouping mechanisms are essential to segregate concurrent sound sources and affect comodulation masking release (CMR). Thu...

journal_title：Hearing research

authors： Zirn S,Hempel JM,Schuster M,Hemmert W

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Mechanical stimulation of the round window (RW) of the cochlea is successfully done with the Vibrant Soundbridge (Med-El), but clinical outcomes show a substantial degree of variability. One source of variability is variation in the static force applied by the stimulator to the round window (Maier et al., 201...

journal_title：Hearing research

authors： Salcher R,Schwab B,Lenarz T,Maier H

更新日期：2014-08-01 00:00:00

abstract：:The etiology of an incidentally discovered temporary threshold shift observed in an experimental animal (Harley guinea pig) is discussed with its potential implications for auditory research. ...

journal_title：Hearing research

authors： Rizer FM,Don M,Sininger Y

更新日期：1987-01-01 00:00:00

abstract：:A growing body of evidence implies that the dorsal cochlear nucleus (DCN) plays an important role in tinnitus. To test the hypothesis that the rostral output of the DCN is necessary for the experience of chronic tinnitus, the dorsal DCN and the dorsal acoustic stria of rats with psychophysical evidence of tinnitus was...

journal_title：Hearing research

authors： Brozoski TJ,Bauer CA

更新日期：2005-08-01 00:00:00

abstract：:The avian basilar papilla (BP) is a likely homolog of the auditory sensory epithelium of the mammalian cochlea, the organ of Corti. During mammalian development Fibroblast growth factor receptor-3 (Fgfr3) is known to regulate the differentiation of auditory mechanosensory hair cells (HCs) and supporting cells (SCs), b...

journal_title：Hearing research

authors： Jacques BE,Dabdoub A,Kelley MW

更新日期：2012-07-01 00:00:00

abstract：:Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated eleme...

journal_title：Hearing research

authors： McCreery D,Yadev K,Han M

更新日期：2018-06-01 00:00:00

abstract：:Several studies have demonstrated that treatment with intracochlear chronic electrical stimulation (CES) protects spiral ganglion cells (SGCs) from degeneration in deafened animals. Other studies could not confirm this effect of CES. The present study examined whether CES in a mode as presented in cochlear implant use...

journal_title：Hearing research

authors： Agterberg MJ,Versnel H,de Groot JC,van den Broek M,Klis SF

更新日期：2010-10-01 00:00:00

abstract：:Immunocytochemical methods were used to examine cryosections of the embryonic and neonatal chicken cochlea in order to study the histological distribution of the Na+,K+-ATPase molecule during maturation. In complementary studies the Na+,K+-ATPase capacity of microdissected freeze-dried substructures of the cochlea was...

journal_title：Hearing research

authors： Schneider ME,Cotanche DA,Fambrough DM,Saunders JC,Matschinsky FM

更新日期：1987-11-01 00:00:00