Colonoscopic polypectomy: silent perforation.

abstract：:Cellular protooncogenes such as c-myc and c-Ha-ras may play important roles in the control of regeneration of the stomach. In this study, in situ hybridization histochemistry and immunohistochemistry were used to determine how these protooncogenes and the corresponding oncoproteins are expressed at the cellular level ...

journal_title：Gastroenterology

authors： Ito T,Hayashi N,Sasaki Y,Morita Y,Kawano S,Fusamoto H,Sato N,Tohyama M,Kamada T

更新日期：1990-06-01 00:00:00

abstract：:By correlating morphological observations with quantitative measurements of net water transport, we determined whether bile salts altered colonic absorptive cells. Epithelial alteration was equivocal and water absorption was uninhibited during infusions of 1 mM deoxycholate or of concentrations of taurocholate less th...

journal_title：Gastroenterology

authors： Saunders DR,Hedges JR,Sillery J,Esther L,Matsumura K,Rubin CE

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND & AIMS:Diarrheal disease is a major cause of morbidity and mortality in infants and children worldwide. Evidence has indicated immature human enterocytes and their interaction with bacteria and enterotoxins may account for the noted increased susceptibility of neonates to diarrhea. Our aim was to characteriz...

journal_title：Gastroenterology

authors： Lu L,Bao Y,Khan A,Goldstein AM,Newburg DS,Quaroni A,Brown D,Walker WA

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatocellular carcinoma (HCC) is often associated with hepatitis B virus (HBV) infection. Cells of most HBV-related HCCs contain HBV-DNA fragments that do not encode entire HBV antigens. We investigated whether these integrated HBV-DNA fragments encode epitopes that are recognized by T cells and whet...

journal_title：Gastroenterology

authors： Tan AT,Yang N,Lee Krishnamoorthy T,Oei V,Chua A,Zhao X,Tan HS,Chia A,Le Bert N,Low D,Tan HK,Kumar R,Irani FG,Ho ZZ,Zhang Q,Guccione E,Wai LE,Koh S,Hwang W,Chow WC,Bertoletti A

更新日期：2019-05-01 00:00:00

abstract：:Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is typically characterized by episodic fever, myalgia, skin rash, conjunctivitis, and abdominal cramps. Recently, mutations in the TNFRSF1A gene on chromosome 12p13 encoding tumor necrosis factor receptor type 1 have been linked to this autoinflammato...

journal_title：Gastroenterology

authors： Haas SL,Lohse P,Schmitt WH,Hildenbrand R,Karaorman M,Singer MV,Böcker U

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND & AIMS:Modulation of the host innate immune response is an attractive means of inhibiting hepatitis C virus (HCV) replication. Having previously determined that expression of the interferon-sensitive gene (ISG)15 protease USP18 is increased in the liver biopsy specimens of patients who do not respond to inte...

journal_title：Gastroenterology

authors： Randall G,Chen L,Panis M,Fischer AK,Lindenbach BD,Sun J,Heathcote J,Rice CM,Edwards AM,McGilvray ID

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND/AIMS:Previous studies have shown that psychological factors play a role in symptom perception among patients with gastroesophageal reflux disease. This report describes the first controlled study showing the effects of relaxation training on symptom reports and esophageal acid exposure in patients with reflu...

journal_title：Gastroenterology

authors： McDonald-Haile J,Bradley LA,Bailey MA,Schan CA,Richter JE

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND & AIMS:Previous studies have indicated that serotonin-3-receptor antagonists might have a sex-specific effect in patients with irritable bowel syndrome with diarrhea (IBS-D). Alosetron has been approved for the treatment of only women, and ramosetron has been approved for the treatment for only men. We perfo...

journal_title：Gastroenterology

authors： Fukudo S,Kinoshita Y,Okumura T,Ida M,Akiho H,Nakashima Y,Nishida A,Haruma K

更新日期：2016-02-01 00:00:00

abstract：:Four patients who underwent transplantation for hepatitis B virus-related liver disease developed rapidly progressive liver failure attributable to recurrent hepatitis B disease typified by hyperbilirubinemia and distinctive hepatocyte ballooning and progressive fibrosis consistent with recently reported fibrosing cho...

journal_title：Gastroenterology

authors： Benner KG,Lee RG,Keeffe EB,Lopez RR,Sasaki AW,Pinson CW

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND & AIMS:In 1988, we reported the first twin study in inflammatory bowel disease. The aim of the current study was to follow up these twins regarding new cases of inflammatory bowel disease and Crohn's disease characteristics using the Vienna classification. METHODS:The official Swedish population register an...

journal_title：Gastroenterology

authors： Halfvarson J,Bodin L,Tysk C,Lindberg E,Järnerot G

更新日期：2003-06-01 00:00:00

abstract：:A patient with post-traumatic seizure disorder developed lymphadenopathy, exfoliative dermatitis, and hepatic failure while on diphenylhydantoin therapy and died in hepatic coma. Autopsy disclosed massive hepatic necrosis. The clinical and pathological pictures are similar to the six previously reported cases of diphe...

journal_title：Gastroenterology

authors： Lee TJ,Carney CN,Lapis JL,Higgins T,Fallon HJ

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND & AIMS:Qualitative endoscopic ultrasound (EUS) elastography is an accurate but subjective tool for the differential diagnosis of solid pancreatic masses. Second-generation EUS elastography allows quantitative analysis of tissue stiffness. We evaluated the accuracy of quantitative, second-generation EUS elast...

journal_title：Gastroenterology

authors： Iglesias-Garcia J,Larino-Noia J,Abdulkader I,Forteza J,Dominguez-Munoz JE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND & AIMS:We investigated the transcriptome of esophageal squamous cell carcinoma (ESCC) cells, activity of gene regulatory (enhancer and promoter regions), and the effects of blocking epigenetic regulatory proteins. METHODS:We performed chromatin immunoprecipitation sequencing with antibodies against H3K4me1,...

journal_title：Gastroenterology

authors： Jiang YY,Jiang Y,Li CQ,Zhang Y,Dakle P,Kaur H,Deng JW,Lin RY,Han L,Xie JJ,Yan Y,Doan N,Zheng Y,Mayakonda A,Hazawa M,Xu L,Li Y,Aswad L,Jeitany M,Kanojia D,Guan XY,Said JW,Yang W,Fullwood MJ,Lin DC,Koeffle

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND & AIMS:The mammalian small intestine is lined by a highly specialized epithelium that functions in the digestion and absorption of nutrients. The molecular mechanisms that direct intestinal epithelial cell morphogenesis and terminal differentiation are poorly understood. We have previously identified Elf3 (E...

journal_title：Gastroenterology

authors： Ng AY,Waring P,Ristevski S,Wang C,Wilson T,Pritchard M,Hertzog P,Kola I

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND & AIMS:Quantitative neurophysiological studies have identified the presence of at least 2 spinal neuronal populations (abrupt and sustained) that are excited by the noxious visceral stimulus colorectal distention. This study examined the effects of the kappa opioid receptor agonists fedotozine and U50488H on...

journal_title：Gastroenterology

authors： Ness TJ

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND & AIMS:Cancer progression/metastases and embryonic development share many properties including cellular plasticity, dynamic cell motility, and integral interaction with the microenvironment. We hypothesized that the heterogeneous nature of hepatocellular carcinoma (HCC), in part, may be owing to the presence...

journal_title：Gastroenterology

authors： Yamashita T,Ji J,Budhu A,Forgues M,Yang W,Wang HY,Jia H,Ye Q,Qin LX,Wauthier E,Reid LM,Minato H,Honda M,Kaneko S,Tang ZY,Wang XW

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND/AIMS:We have identified several clones specifically expressed during malignant cell proliferation by screening a complementary DNA library constructed from a human primary liver cancer with subtractive probes. One clone was identified as the glutamine synthetase (GS) transcript. Its expression is tightly reg...

journal_title：Gastroenterology

authors： Christa L,Simon MT,Flinois JP,Gebhardt R,Brechot C,Lasserre C

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The MDR1 gene encodes P-glycoprotein 170, an efflux transporter that is highly expressed in intestinal epithelial cells. The MDR1 exonic single nucleotide polymorphisms (SNPs) C3435T and G2677T have been shown to correlate with activity/expression of P-glycoprotein 170. METHODS:This was a case-cont...

journal_title：Gastroenterology

authors： Ho GT,Nimmo ER,Tenesa A,Fennell J,Drummond H,Mowat C,Arnott ID,Satsangi J

更新日期：2005-02-01 00:00:00

abstract：:Hepatic morphology and immunocytology were evaluated in 4 children with clinical and immunologic characteristics of the acquired immune deficiency syndrome or acquired immune deficiency syndrome related complex. All 4 children had hepatomegaly and increased serum alanine and aspartate aminotransferase activity. Both l...

journal_title：Gastroenterology

authors： Duffy LF,Daum F,Kahn E,Teichberg S,Pahwa R,Fagin J,Kenigsberg K,Kaplan M,Fisher SE,Pahwa S

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND & AIMS:We assessed the influence of genetic variants in the hepatitis B virus (HBV) core, which is a principal immunologic target, on the progression to hepatocellular carcinoma (HCC) in a cohort of 4841 male HBV carriers followed up for 16 years. METHODS:First, baseline sera from 116 HCC cases and 154 cont...

journal_title：Gastroenterology

authors： Sung FY,Jung CM,Wu CF,Lin CL,Liu CJ,Liaw YF,Tsai KS,Yu MW

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND & AIMS:Several studies have reported that low doses of interferon can delay the development of hepatocellular carcinoma (HCC) and progression of chronic hepatitis C. We investigated the incidence of clinical events among participants of the Evaluation of PegIntron in Control of Hepatitis C Cirrhosis (EPIC)3 ...

journal_title：Gastroenterology

authors： Bruix J,Poynard T,Colombo M,Schiff E,Burak K,Heathcote EJ,Berg T,Poo JL,Mello CB,Guenther R,Niederau C,Terg R,Bedossa P,Boparai N,Griffel LH,Burroughs M,Brass CA,Albrecht JK,EPIC3 Study Group.

更新日期：2011-06-01 00:00:00

abstract：:Colchicine can induce the malabsorption of vitamin B12 and other nutrients. Previous investigations have suggested but not proved that this malabsorption was due to a lesion in the ileal mucosa. Employing the receptor assay of M. Katz and B. A. Cooper (J Clin Invest 54:733-739, 1974), the authors have observed a dose-...

journal_title：Gastroenterology

authors： Stopa EG,O'Brien R,Katz M

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND & AIMS:According to the National Center for Health Statistics (NCHS), chronic liver disease and cirrhosis is the 12(th) leading cause of death in the United States. However, this single descriptor might not adequately enumerate all deaths from liver disease. The aim of our study was to update data on liver m...

journal_title：Gastroenterology

authors： Asrani SK,Larson JJ,Yawn B,Therneau TM,Kim WR

更新日期：2013-08-01 00:00:00

abstract：:The effects of chronic mild restraint on the susceptibility of the rat gastric mucosa to ethanol or cold-restraint injury were studied. Gastric mucosas of animals subjected to chronic mild restraint exhibited less damage when bathed with 40% ethanol than those of control animals. This reduced damage was observed with ...

journal_title：Gastroenterology

authors： Wallace JL,Track NS,Cohen MM

更新日期：1983-08-01 00:00:00

abstract：:The target appearance of grey scale ultrasound is thought to be a characteristic sign of gastrointestinal wall thickening. It consists of a strong echogenic center surrounded by a sonolucent rim. In a prospective controlled study, the sensitivity and specificity of the ultrasonic B-scan for Crohn's disease were invest...

journal_title：Gastroenterology

authors： Sonnenberg A,Erckenbrecht J,Peter P,Niederau C

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND & AIMS:It has been proposed that activation of the sympathetic nervous system causes a rightward shift in the renal autoregulatory curve such that renal blood flow is critically dependent on renal perfusion pressure and that this contributes to the development of the hepatorenal syndrome. The aims of the stu...

journal_title：Gastroenterology

authors： Stadlbauer V,Wright GA,Banaji M,Mukhopadhya A,Mookerjee RP,Moore K,Jalan R

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND & AIMS:The revised Bethesda guidelines for Lynch syndrome recommend microsatellite instability (MSI) testing all colorectal cancers in patients diagnosed before age 50 years and colorectal cancers diagnosed in patients between ages 50 and 59 years with particular pathology features. Our aim was to identify p...

journal_title：Gastroenterology

authors： Jenkins MA,Hayashi S,O'Shea AM,Burgart LJ,Smyrk TC,Shimizu D,Waring PM,Ruszkiewicz AR,Pollett AF,Redston M,Barker MA,Baron JA,Casey GR,Dowty JG,Giles GG,Limburg P,Newcomb P,Young JP,Walsh MD,Thibodeau SN,Lindor NM

更新日期：2007-07-01 00:00:00

abstract：:The courses of 38 patients with severe, uncomplicated acute colitis (16 with Crohn's colitis and 22 with ulcerative colitis) were analyzed retrospectively. The patients were placed on total parenteral nutrition and treated concomitantly with corticosteroids, antibiotics (often metronidazole), sulfasalazine, and/or aza...

journal_title：Gastroenterology

authors： Sitzmann JV,Converse RL Jr,Bayless TM

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND & AIMS:Crohn's disease (CD) and ulcerative colitis (UC) are associated with chronic tissue damage and continuous tissue repair. A central, but not well-characterized, event during this process is the migration of activated fibroblasts to the wound. METHODS:Human colonic lamina propria fibroblasts (CLPF) wer...

journal_title：Gastroenterology

authors： Leeb SN,Vogl D,Gunckel M,Kiessling S,Falk W,Göke M,Schölmerich J,Gelbmann CM,Rogler G

更新日期：2003-11-01 00:00:00

abstract：:Chlorpromazine (CPZ) is a long recognized cause of jaundice, but the mechanism by which this agent produces icteric liver disease is not well defined. This study examined some effects of CPZ administration on bilirubin metabolism and biliary secretion in the rat. Acute CPZ treatment (25 mg per kg intravenously) produc...

journal_title：Gastroenterology

authors： Knodell RG

更新日期：1975-10-01 00:00:00