Abstract：
:The classical form of Barlow's disease or infantile scurvy, with bruises, broken bones and sores that will not heal, is rarely seen today, but it seems to be reappearing under a different guise, when infants with borderline vitamin C depletion are assaulted with too many inoculations at one time.Moreover, it is now sometimes mistakenly diagnosed as child abuse.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Clemetson CAdoi
10.1016/s0306-9877(02)00114-7keywords:
subject
Has Abstractpub_date
2002-07-01 00:00:00pages
52-6issue
1eissn
0306-9877issn
1532-2777pii
S0306987702001147journal_volume
59pub_type
杂志文章abstract：:Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the largest current health challenge for the society. At the moment, the therapeutic strategies to deal with this disease are only supportive. It is well known that zinc (Zn) possesses a variety of dir...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109848
更新日期：2020-11-01 00:00:00
abstract：:The existence of homosexuality in humans poses a problem for evolutionary theory. Exclusive male homosexuality has a catastrophic effect on reproduction and yet inherited factors appear to contribute to it. Previous attempts to resolve this conundrum are inconsistent with aspects of evolutionary theory. Additional lim...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(02)00363-8
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation (AF) is the most common cardiac arrhythmia. Many studies have investigated the cause for the development of AF, however, the question remains unanswered. METHODS:A comparison of hydrodynamics between AF and sinus rhythm was performed. RESULTS:I proposed the hypothesis that atrial fibril...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2015.11.028
更新日期：2016-01-01 00:00:00
abstract：:A case-control study was conducted in order to test the hypothesis that a reduced exposure to human seminal factors in the early reproductive life of women is a risk factor in breast cancer. The relative risk of exposure to the hypothetical semen-factor deficiency is 4.7 times greater for breast-cancer patients than f...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(78)90051-8
更新日期：1978-03-01 00:00:00
abstract：:In this editorial, we provide concise suggestions to help individuals decide what scientific papers to read and how to read them. We do so because--like others--we are frequently asked by people with interest in science as to how to effectively surf today's information tsunami. This is particularly important in, but n...
journal_title：Medical hypotheses
pub_type： 社论
doi：10.1016/j.mehy.2009.05.002
更新日期：2009-09-01 00:00:00
abstract：:Therapies for preventing reperfusion injury (RI) have been widely studied. However, the attempts to transfer cardioprotective therapies for reducing RI from experiments into clinical practice have been so far unsuccessful. Pathophysiological mechanisms of RI are complicated and compose of many pathways e.g. hypercontr...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109558
更新日期：2020-04-01 00:00:00
abstract：:Dementia and other causes of functional disability can create considerable burdens for families and society as a whole, but it may be possible to partially alleviate this strain through technical innovations that replace some functions of human caregivers. This article proposes the hypothesis that cell phones, interne...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2005.11.045
更新日期：2006-01-01 00:00:00
abstract：:From biographical data sources on ranking scientists, I was able to identify 35 centenarians. Among these, only one (Michel Chevereul from France) lived before the 20th century. Since the remaining 34 individuals became centenarians only from 1965, I propose that centenarian scientists are an unusual cluster, first fo...
journal_title：Medical hypotheses
pub_type： 历史文章,杂志文章
doi：10.1054/mehy.2001.1480
更新日期：2001-12-01 00:00:00
abstract：:In a survey based on the biographical sketches, obituary notes and eulogies of notable scientists, eight were identified as belonging to an elite group, having authored more than 1000 research publications, which include books, monographs and patents. They were, in chronological order, Thomas Alva Edison, Paul Karrer,...
journal_title：Medical hypotheses
pub_type： 历史文章,杂志文章
doi：10.1016/0306-9877(92)90179-g
更新日期：1992-10-01 00:00:00
abstract：:The objective of this study was to test the hypothesis that the regular practice of mindfulness meditation is associated with increased physiological levels of melatonin. Melatonin may be related to a variety of biologic functions important in maintaining health and preventing disease, including breast and prostate ca...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(95)90299-6
更新日期：1995-01-01 00:00:00
abstract：:Cocaine is one of the principal drugs of abuse. Although impressive advances have been made, unanswered questions remain concerning mechanism of toxicity and addiction. Discussion of action mode usually centers on receptor binding and enzyme inhibition, with limited attention to events at the molecular level. This rev...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2004.06.028
更新日期：2005-01-01 00:00:00
abstract：:According to the theory presented herewith, neoplasia results solely from stem cell depletion. Besides serving as tissue progenitors, stem cells are postulated to secrete a vital substance 'A' necessary for proper tissue function. Carcinogens interfere with 'A' production mainly by destroying stem cells and since the ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(85)90026-x
更新日期：1985-11-01 00:00:00
abstract：:Cell-mediated immunity is generally regarded as the essential factor in recovery from measles infection. In other viral infections humoral immunity has been considered a critical factor when antibody titres were correlated with outcome or when serum therapy proved protective. A review of available studies of severe-to...
journal_title：Medical hypotheses
pub_type： 杂志文章,评审
doi：10.1016/0306-9877(87)90020-x
更新日期：1987-07-01 00:00:00
abstract：:Medical Hypotheses exists to give ideas and speculations in medicine a fair hearing. Doing this is not easy. Most conventional journals would regard some of what is published here as questionable, most referees would reject it as 'unproven'. We have more liberal standards, for reasons we have presented before. But we ...
journal_title：Medical hypotheses
pub_type： 社论
doi：10.1016/j.mehy.2004.10.003
更新日期：2005-01-01 00:00:00
abstract：:Based on a consideration of biochemical mechanisms, rational methods for the prevention of cancer and for its positive regression are presented. It is demonstrated that the means employed are fundamentally opposed so that if the preventive method were to be used after the onset of cancer, it would only accelerate its ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(81)90030-x
更新日期：1981-04-01 00:00:00
abstract：BACKGROUND:Special feet connected to a prosthesis, prosthetic sports feet, enable athletes with a lower limb amputation to run. The selection of a prosthetic sports feet is usually based on body weight and preferred sports performance. The selection of a prosthetic sport feet is also based on clinicians who likely have...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109869
更新日期：2020-10-01 00:00:00
abstract：:Photodynamic therapy (PDT) is a new therapeutic approach for the treatment of malignant tumors. Hyperbaric oxygen (HBO(2)) shows beneficial effects in various modalities of cancer interventions. Tumor cells tend to accumulate large amount of iron. There is interaction between tissue content of oxygen, iron, free radic...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2005.12.052
更新日期：2006-01-01 00:00:00
abstract：:Nitrosamines have been identified in vaginal secretions of women with trichomoniasis. Both nitrites and amines the elements for nitrosamine synthesis are produced by the abnormal-predominantly anaerobic-vaginal flora of patients with bacterial vaginosis/trichomoniasis. The final formation of nitrosamines could also de...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(84)90159-2
更新日期：1984-12-01 00:00:00
abstract：:In view of the limited success of available treatment modalities for metastatic tumor, alternative and complementary strategies need to be developed. Oncolytic viruses are capable of selective replication in malignant cells and therefore offer levels of potency and specificity that are potentially far higher than conv...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.07.032
更新日期：2008-01-01 00:00:00
abstract：:Chronic active Epstein-Barr virus (EBV) infection has been recognized as clonal non-neoplastic lymphoproliferative diseases. However, some reports of cases with a multiphenotypic expansion of EBV-infected lymphocytes give rise to questions of how EBV infects multiphenotypic lymphocytes and whether chronic active EBV i...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2004.03.012
更新日期：2004-01-01 00:00:00
abstract：:Electron spin resonance (ESR) spin trapping methodology has been used to study the reactions of manganese dusts with glutathione, employing alpha-(4-pyridyl-1-oxide)-N-tert-butyl-nitrone (PBN) and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as spin traps. The results show evidence for the glutathionyl radical formation in...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(90)90184-g
更新日期：1990-10-01 00:00:00
abstract：:Many parasites induce characteristic changes in their host. The effect of Toxoplasma gondii infection on the cerebrum and neuropsychiatric patients has been increasingly emphasized in recent years. T. gondii has a high affinity for brain tissue where tachyzoites may form tissue cysts and persist for a life long time. ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2009.04.013
更新日期：2009-11-01 00:00:00
abstract：:A hypothesis is presented describing the operation of mammalian brains on the basis of rapid percussion chemical reactions and shock waves generated by such reactions. It is shown that the products of these are various chemical compounds identified as present in the brain. The manner in which the brain deals with vari...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(02)00296-7
更新日期：2002-12-01 00:00:00
abstract：:Non-invasive molecular analysis of fetal DNA is the diagnostic goal of prenatal medicine. Circulating fetal DNA can be detected in maternal plasma. Recently, it has been detected in the urine of pregnant women. We hypothesize that fetal DNA is present also in maternal saliva and that advances in stabilization and isol...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2009.09.022
更新日期：2010-02-01 00:00:00
abstract：:It is suggested here that a Hemoglobin S (HbS)-mediated membrane oxidant injury is responsible for both the protection from malaria infection in the heterozygous sickle cell state, and for a critical pathologic process in homozygous sickle cell disease. This suggestion is arrived at by applying to the HbS condition th...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(87)90135-6
更新日期：1984-07-01 00:00:00
abstract：:Osteoarthritis (OA) is a chronic, degenerative disorder of multifactorial aetiology, characterized by loss of articular cartilage and periarticular bone remodelling. Goals of managing OA include controlling pain, maintaining and improving function and health-related quality of life, and limiting functional impairment....
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.01.084
更新日期：2007-01-01 00:00:00
abstract：:Clinical studies have shown that moderately intense physical activity effectively treats various types of depression. Beneficial effects have been reported in the acute phase of the disease as well as in a long-term perspective. In addition, epidemiological studies have shown that inactivity increases the risk of depr...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2012.10.007
更新日期：2013-01-01 00:00:00
abstract：:Endophthalmitis following pars-plana procedures such as a vitrectomy vitreo-retinal procedures has been infrequently reported in literature. The cited incidence is about 0.1% to 0.2%. In the 8 cases of endophthalmitis that have been reported in literature, the prognosis has been indicated as very poor due to a delay i...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.2001.1490
更新日期：2002-06-01 00:00:00
abstract：:Abnormal fluctuations of acetylcholine and serotonin might cause, or be correlated with, a variety of symptoms. This communication cites evidence which suggests that fluctuations of serotonin might have a causative role in migraine, mania, and depression and that fluctuations of acetylcholine might have a causative ro...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(93)90011-e
更新日期：1993-05-01 00:00:00
abstract：:The origin and initiating features of PBC remain obscure despite decades of study. However, recent papers have demonstrated loss of canals of Hering (CoH) to be the earliest histologic change in liver biopsy specimens from patients with primary biliary cholangitis (PBC). We posit that CoH loss prior to significant inf...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109680
更新日期：2020-03-16 00:00:00
