Abstract:
BACKGROUND:Contrast echocardiography has been used as a clinical method for more than 20 years. Using conventional ultrasound techniques the clinical use of contrast was limited. Now the development of "contrast specific" imaging modalities has increased the indications for contrast echocardiography. CONTRAST AGENTS:For clinical use two classes of contrast agents are available: 1. "right heart" contrast media (Echovist, agitated solutions), which do not cross the pulmonary vascular bed following intravenous injection and which can be used with conventional (fundamental) imaging methods, 2. "left heart" contrast media (Levovist, Optison, SonoVue) which need "contrast specific" imaging modalities for optimal use. INDICATIONS:Despite of the developments in Doppler methods and transesophageal echocardiography "right heart" contrast media still are needed in some patients with atrial and pulmonary shunts, complex congenital heart disease, noisy Doppler recordings of tricuspid regurgitation. For "left heart" contrast media improvement of endocardial border definition is the most important indication, which has been validated in a series of well performed studies. Therefore contrast enhanced recordings are recommended in the clinical echo laboratory when unenhanced recordings are suboptimal. Coronary flow reserve of the LAD can be measured using contrast enhanced Doppler echocardiography. All contrast specific imaging modalities provide assessment of myocardial perfusion. The previously used imaging modalities (Harmonic B mode, Pulse Inversion and Harmonic Power Doppler) did not provide sufficient myocardial contrast signals using real-time imaging. Although intermittent imaging resulted in good myocardial opacification, this modality did not gain wider clinical acceptance. NEW TECHNOLOGIES:Using new contrast specific imaging technologies like Power Pulse Inversion, Power Modulation and Coherent Imaging myocardial perfusion can be evaluated in "real-time". Thus simultaneous assessment of left ventricular wall motion and myocardial perfusion became a reality and facilitated the data acquisition. New ultrasound contrast media like SonoVue can be used for all imaging modalities. Recent studies have demonstrated that the information derived from myocardial contrast echocardiography provides clinically relevant information on top of the findings obtained from conventional left ventricular wall motion analysis.
journal_name
Herzjournal_title
Herzauthors
Becher Hdoi
10.1007/s00059-002-2371-xkeywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
201-16issue
3eissn
0340-9937issn
1615-6692journal_volume
27pub_type
杂志文章相关文献
HERZ文献大全abstract::In eleven patients with aortic dissection or perforated endocarditic aortic wall abscess cavity, the diagnostic usefulness of Color Doppler Echocardiography (CDE) for the identification of true and false lumen as well as the perforation jet was assessed by comparison with the findings of angiography, digital subtracti...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract::Appraisal of the risk to which outpatients with chest pain are exposed is an important clinical problem that frequently occurs. The need to decide in day-to-day practice between a conservative or invasive approach in patients with chest pain is often difficult and the decision has grave implications. Stress echocardio...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-005-2688-3
更新日期:2005-12-01 00:00:00
abstract::The prevalence of overweight and obesity in children and adolescents is increasing. In Germany, 10-20% of children and youth are overweight and obese. Childhood obesity is associated with cardiovascular and other comorbidities. 25% suffer from arterial hypertension and/or hypercholesterolemia, 1% from diabetes mellitu...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-006-2860-4
更新日期:2006-09-01 00:00:00
abstract::To assess the results of transluminal coronary angioplasty (TCA), 42 patients (mean age 50 years) with for coronary artery disease were investigated at rest and during exercise with the ECG (n = 40), thallium-201 myocardial scintigraphy (n = 23) and equilibrium-radionuclide ventriculography (n = 32). Each method of st...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00
abstract::Via the internet smartphones allow the download of applications ("Apps") that can address various requirements of daily life. These technical advances create new opportunities to better meet needs of patients suffering from hypertension. This may apply particularly for medication adherence, blood pressure control and ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3685-y
更新日期:2012-11-01 00:00:00
abstract::Diabetes is associated with the development of premature cardiovascular disease (CVD), which relates to the clustering of risk factors such as dyslipidaemia, hypertension, obesity and hyperglycaemia in the presence of insulin resistance. In addition, diabetes is associated with an inflammatory and pro-thrombotic envir...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-016-4414-8
更新日期:2016-05-01 00:00:00
abstract::Myocardial infarction (MI) as an acute and life-threatening complication of coronary heart disease is one of the most frequent causes of death in Germany. Therefore, diagnosis, risk stratification and treatment of acute MI are of great clinical relevance. Specific recommendations concerning diagnosis of acute MI can b...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-008-3103-7
更新日期:2008-03-01 00:00:00
abstract::Implantable defibrillators (ICDs) have to be replaced after 4-6 years due to battery depletion. Therefore, 195-267 ICDs may be necessary for 100 ICD patients, if device longevity is 6 and 4 years, respectively. In Germany, 35% of all ICDs were replacements in 2003. The percentage of replacements will probably increase...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-005-2744-z
更新日期:2005-11-01 00:00:00
abstract::Of 89 children with angiographically-documented pulmonic stenosis and intact ventricular septum (PST), 76 (85.4%) had valvular, 11 (12.4%) infundibular and 2 (2%) had supravalvular lesions. Standard, p. a. view, chest X-rays of children with a mean age of 6 7/12 years were evaluated with respect to 1. cardiac enlargem...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::Our own previous studies of the composition of the extracellular matrix of human failing hearts showed that collagen VI seems to play a major role in the origin of cardiac fibrosis. Therefore, collagen VI was investigated in more detail in tissue samples taken from clinically normal left ventricle and from myocardium ...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Radiofrequency catheter ablation has established as the first line therapy for the curative treatment of patients with accessory pathway. Atrioventricular accessory pathways irrespective of the exact localisation can be successfully ablated in more than 90% of all cases. Severe complications associated with the ablati...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03044318
更新日期:1998-06-01 00:00:00
abstract::In ten patients with angiographically-documented coronary artery disease, stable angina pectoris and reproducible exercise-induced ST-segment depression, the extent and duration of antiischemic and antianginal effects of transdermal nitroglycerin patches delivering 10 mg/24 hours were investigated according to a doubl...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:Galectin-3 has been reported as a mediator of heart failure (HF) development and progression. Most studies, however, have been conducted on patients with chronic HF rather than acute HF (AHF). The aim of this study was to confirm galectin-3 as a prognostic marker in subjects with AHF and to investigate its p...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-017-4538-5
更新日期:2018-03-01 00:00:00
abstract::The progress in cardiology during the last 50 years can best be studied by looking at the diagnostics and treatment of patients with aortic valve stenosis. Previously, the clinical examination, electrocardiography (ECG) and chest X‑ray were used before heart catheterization, which included a transseptal puncture to co...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-020-04980-6
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:The Braunwald classification and TIMI (Thrombolysis In Myocardial Infarction) risk score are used to stratify cardiovascular risk in patients with unstable angina (UA). However, these scores have a limited capacity in the practice of cardiology. OBJECTIVES:This study sought to develop a new score, based on ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-014-4141-y
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Experimental and clinical studies have suggested that the presence of fragmented QRS complex (fQRS) is associated with various cardiovascular diseases. fQRS may predict major adverse cardiovascular events (MACE). The current meta-analysis was performed using clinical outcome studies to evaluate the role of f...
journal_title:Herz
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00059-014-4155-5
更新日期:2015-03-01 00:00:00
abstract::Blood pressure, together with proteinuria, represents one of the most important factors in the progression of chronic renal failure (CRF). Antihypertensive therapy is beneficial to slow down the progression of a variety of chronic renal diseases, no matter what the cause. Intraglomerular hypertension, increased glomer...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-003-2508-6
更新日期:2004-05-01 00:00:00
abstract::Many electrophysiological and histological investigations have demonstrated that post-operative dysrhythmias which occur in children with heart disorders requiring extensive surgical treatment in the area of the right atrium, are often caused by intraoperative lesions of the sinoatrial node. Accordingly, accurate dete...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:Renal denervation (RDN) has been proposed as a novel antihypertensive intervention for treating resistant hypertension. It remains to be investigated which patient groups can potentially benefit from RDN. The present study aimed to evaluate the efficacy and safety of RDN in patients with mild-moderate resist...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-017-4664-0
更新日期:2019-08-01 00:00:00
abstract::The European Society of Cardiology (ESC) has recently published new guidelines on the diagnosis and management of chronic coronary syndromes (CCS). Due to variable symptoms, objective tests are often necessary to confirm the diagnosis, exclude alternative diagnoses, and assess the severity of underlying disease. This ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-020-04935-x
更新日期:2020-08-01 00:00:00
abstract::Heart failure remains a frequent cause of death and is the leading reason for hospitalization in Germany although therapeutic options have significantly increased over the past years particularly in heart failure with reduced ejection fraction. Clinical symptoms are usually preceded by cardiac remodeling, which was or...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-016-4530-5
更新日期:2017-02-01 00:00:00
abstract::Coronary artery disease is still the no. 1 killer in the developed countries and must thus be detected and treated at an earlier stage. If coronary artery disease is advanced, patients have to be examined regarding the need for revascularization. For secondary prevention, of course, an optimal change of life style and...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/pl00001975
更新日期:2000-09-01 00:00:00
abstract::Despite great advances in the pathophysiology and etiology of myocarditis, the clinical diagnosis of myocarditis in daily clinical practise remains challenging. Often the diagnosis was not clear because of the heterogeneity of clinical symptoms and the lack of guidelines for adequate diagnostic requirements and consec...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-3988-7
更新日期:2013-12-01 00:00:00
abstract::Besides diagnosis of the mechanism of mitral regurgitation accurate evaluation of the severity is of critical importance for the assessment of prognosis and planning of therapy. Current recommendations are differentiating two levels of evaluation of severity, (1) a rapid, basic evaluation, and (2) an extended, quantit...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-006-2774-1
更新日期:2006-02-01 00:00:00
abstract::This review summarizes the present knowledge concerning the hemodynamic and myocardial effects of various pacing modalities with special reference to the importance of heart rate variability and atrioventricular synchronization. An adequate increase in heart rate, irrespective of atrioventricular synchronization, seem...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Limited data exist on bioresorbable scaffolds (BRS) in patients with acute coronary syndrome (ACS). The aim of the present study was to evaluate novolimus-eluting BRS (DESolve) as interventional treatment for patients with ACS, and to compare its 12-month outcomes with the everolimus-eluting bioresorbable sc...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-019-4822-7
更新日期:2020-12-01 00:00:00
abstract::Modern therapeutic options in ischemic coronary disease such as thrombolysis, coronary angioplasty, new emerging strategies in treating heart failure and secondary prevention have resulted in decreasing cardiac mortality over the last ten years. In the era of interventional cardiology a new focus of clinical interest ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
abstract::Chronic heart failure has an age-dependent prevalence of 2% and is therefore one of the most frequent diseases in western societies. A reduced hemoglobin concentration according to the definition of the World Health Organization is a common comorbidity affecting more than half of all heart failure patients. Elderly pa...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-3901-4
更新日期:2013-09-01 00:00:00
abstract::The decision to anticoagulate patients with atrial fibrillation (AF) involves weighting the risk of an embolic event without therapy versus the risk of a hemorrhagic event on therapy. Improved methods of monitoring anticoagulation with the International Normalized Ratio (INR), and recent evidence of the efficacy and s...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1993-02-01 00:00:00
abstract::Since the first comprehensive computerized videometric systems for quantitative assessment of the dynamic morphology and function of the heart have been developed, angiocardiographic image generation and computer aided evaluation have improved considerably. As a second method for morphological imaging echocardiography...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00