Abstract:
:This review summarizes the present knowledge concerning the hemodynamic and myocardial effects of various pacing modalities with special reference to the importance of heart rate variability and atrioventricular synchronization. An adequate increase in heart rate, irrespective of atrioventricular synchronization, seems to be the most important denominator for cardiac output and exercise tolerance. Atrioventricular synchronization will add some hemodynamic benefit, which is most pronounced at rest. The importance of a rate-adaptive atrioventricular delay and a normalized ventricular activation sequence remains, however, to be fully established. Myocardial oxygen consumption does not differ during fixed rate ventricular pacing, atrial synchronous or non-synchronous rate-adaptive ventricular pacing, neither at rest nor during exercise, despite a higher cardiac output during the rate-adaptive modes. This indicates a more "economic" cardiac work with rate-adaptive pacing. Fixed rate ventricular pacing, on the other hand, may have negative long-term effects on myocardial function due to an increased cardiac sympathetic activity compared with rate-adaptive ventricular pacing, in particular during exercise. It is concluded that the majority of pacemaker-dependent patients will benefit from restored rate variability, with the atrial electrogram still being the most appropriate trigger for rate-adaptive ventricular pacing. When the atrial signal cannot be used or when it is unreliable, however, other rate-triggering signals can be used with comparable results regarding hemodynamics and exercise tolerance.
journal_name
Herzjournal_title
Herzauthors
Nordlander R,Hedman Asubject
Has Abstractpub_date
1991-06-01 00:00:00pages
149-57issue
3eissn
0340-9937issn
1615-6692journal_volume
16pub_type
杂志文章,评审相关文献
HERZ文献大全abstract:BACKGROUND:There is an increasing prevalence of older adults (> 65 years) with hypertension and the need for antihypertensive medication. It is well established that elderly hypertensive patients benefit from drug treatment with regards to cardiovascular morbidity and mortality. Due to the comorbidity and reduced quali...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:10.1007/pl00002050
更新日期:2001-11-01 00:00:00
abstract::Eosinophilic myocarditis is caused by activation of eosinophilic granulocytes whereby there is a release of eosinophilic granules. Quite a few of the released compounds, especially eosinophilic cationic proteins, have a tissue-damaging effect also in the myocardium. Eosinophilia may be due to hypersensitivity, parasit...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3701-2
更新日期:2012-12-01 00:00:00
abstract::Left ventricular hypertrophy (LVH) is a strong, independent predictor of cardiovascular events and all-cause mortality. Patients with LVH are at increased risk for stroke, coronary heart disease, congestive heart failure, and sudden cardiac death. Hypertension is a major influence on the development of LVH. The progno...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-006-2819-5
更新日期:2006-06-01 00:00:00
abstract::Despite great advances in the pathophysiology and etiology of myocarditis, the clinical diagnosis of myocarditis in daily clinical practise remains challenging. Often the diagnosis was not clear because of the heterogeneity of clinical symptoms and the lack of guidelines for adequate diagnostic requirements and consec...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-3988-7
更新日期:2013-12-01 00:00:00
abstract::Left ventricular function was assessed in 38 patients two to six days after acute myocardial infarction using nuclear angiocardiography and the following parameters were measured: Left ventricular end-diastolic (LVEDV) and end-systolic volumes (LVESV), ejection fraction (LVEF), indices of left ventricular filling and ...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-003-2517-5
更新日期:2003-12-01 00:00:00
abstract::New therapeutic options such as the highly active antiretroviral therapy (HAART) have significantly improved morbidity and mortality of HIV-infected patients. Consequently, age-related diseases become more manifest. In addition, HIV infection itself causes certain cardiovascular morbidity. Therefore, treatment of card...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-005-2723-4
更新日期:2005-09-01 00:00:00
abstract::From April 1973 through March 1978, 34 patients with univentricular heart and outlet chamber underwent repair by septation of the ventricle. Three had normally related great arteries in which the pulmonary artery arose from the outlet chamber. Six patients had an anterior aorta arising from an anterior or right-sided ...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1979-04-01 00:00:00
abstract::The diagnosis of varicose veins is based on historical details pertaining to risk factors such as familial preponderance, advanced age, overweight, multiple births, professional activities carried out mainly in the standing or sitting position, use of oral contraceptives, diuretics or drugs which lower venous tone. Sw...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1989-10-01 00:00:00
abstract::Electrophysiologic studies in patients with the Wolff-Parkinson-White (WPW) syndrome are performed for diagnostic and therapeutic reasons. Surface electrocardiographic leads plus intracardiac electrograms from different locations are stimultaneously recorded. Programmed electrical stimulation of the heart permits conf...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was the analysis of long-term results in patients with hemodynamically significant mitral valve disease due to extensively calcified mitral annulus who underwent decalcification and patch reconstruction. PATIENTS AND METHODS:Between 1996 and 2008 a total of 109 patients underwent surger...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:10.1007/s00059-011-3576-7
更新日期:2012-11-01 00:00:00
abstract::Many electrophysiological and histological investigations have demonstrated that post-operative dysrhythmias which occur in children with heart disorders requiring extensive surgical treatment in the area of the right atrium, are often caused by intraoperative lesions of the sinoatrial node. Accordingly, accurate dete...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-003-2524-6
更新日期:2003-12-01 00:00:00
abstract::To assess the results of transluminal coronary angioplasty (TCA), 42 patients (mean age 50 years) with for coronary artery disease were investigated at rest and during exercise with the ECG (n = 40), thallium-201 myocardial scintigraphy (n = 23) and equilibrium-radionuclide ventriculography (n = 32). Each method of st...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00
abstract::The success of percutaneous transluminal coronary angioplasty (PTCA) is limited by vessel dissection with subsequent vessel occlusion in the acute phase and by restenosis chronically. The implantation of intracoronary stents allows to manage acute complications more efficiently and reduce restenosis rate. Anticoagulat...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:The"no-reflow" phenomenon is associated with a worse prognosis at follow-up for patients with acute ST-segment elevation myocardial infarction (STEMI). Predicting and preventing no-reflow is therefore a crucial step in improving the prognosis of STEMI patients. The purpose of this study was to investigate the...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-4026-5
更新日期:2015-05-01 00:00:00
abstract::The ideal heart valve prosthesis has not been developed. The today available mechanical and biological prostheses are far from perfect concerning thrombogenesis, mechanical durability and hemodynamic performance. Failure of an implanted valve is possible due to inadequate indication, inadequate surgical technique and ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03043406
更新日期:1998-11-01 00:00:00
abstract::Besides diagnosis of the mechanism of mitral regurgitation accurate evaluation of the severity is of critical importance for the assessment of prognosis and planning of therapy. Current recommendations are differentiating two levels of evaluation of severity, (1) a rapid, basic evaluation, and (2) an extended, quantit...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-006-2774-1
更新日期:2006-02-01 00:00:00
abstract::Transcatheter procedures have been adopted as novel treatment strategy for patients with valvular heart disease, particularly for those who are inoperable or at high risk for surgical valve procedures. Significant technological advances have resulted in an improvement of devices for transcatheter aortic valve replacem...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-015-4207-5
更新日期:2015-04-01 00:00:00
abstract::Non-invasive tomographic imaging modalities have recently contributed to identifying aortic intramural hematoma, a variant form of classic dissection, which is characterized by the absence of an intimal tear and thus the absence of direct flow communication, and which represents an important disease entity in acute ao...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-011-3501-0
更新日期:2011-09-01 00:00:00
abstract::Endothelial cells synthesize and metabolize vasoactive substances which are involved in the regulation of vascular tone. Among these factors, the endothelium-derived nitric oxide (NO) appears to be of major importance. Many studies observed an impairment of the generation, release, or the diffusion of endothelial NO a...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1992-10-01 00:00:00
abstract::Implantable defibrillators (ICDs) have to be replaced after 4-6 years due to battery depletion. Therefore, 195-267 ICDs may be necessary for 100 ICD patients, if device longevity is 6 and 4 years, respectively. In Germany, 35% of all ICDs were replacements in 2003. The percentage of replacements will probably increase...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-005-2744-z
更新日期:2005-11-01 00:00:00
abstract::A congenital aneurysm of the ductus arteriosus Botalli was detected by chest X-ray as an intrathoracic mass in a 7-day-old infant. Following confirmation of the diagnosis by echocardiography and MRI the aneurysm was successfully resected via left lateral thoracotomy without cardiopulmonary bypass. The postoperative co...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/pl00001985
更新日期:2000-11-01 00:00:00
abstract::During the last decade, we have witnessed substantial improvements in the therapeutic options for pulmonary arterial hypertension (PAH), including true innovations targeting some of the mechanisms involved in the pathogenesis of this devastating disease. Intravenous epoprostenol was the first drug to improve symptoms ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-005-2684-7
更新日期:2005-06-01 00:00:00
abstract::Diastolic function in coronary artery disease is modified to a variable extent. There are distinct abnormalities produced during acute ischemia, and following myocardial infarction. The pathophysiology of diastolic abnormalities in these two syndromes is reviewed. During acute ischemia filling pressures of the left ve...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1991-02-01 00:00:00
abstract::Atrial fibrillation is by far the most common cardiac arrhythmia in humans. The incidence of atrial fibrillation increases with age and will increase even more in the future due to the demographic changes in the population. Therefore, this arrhythmia will have a growing clinical and socioeconomic impact. Although ther...
journal_title:Herz
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00059-017-4565-2
更新日期:2017-06-01 00:00:00
abstract::In the last years several new data allow a controversial but convincing interpretation of the pathogenesis of atherosclerosis (arteriosclerosis). Atherosclerosis can be apparently the result of ultrachronic persistent infection by Chlamydia pneumoniae and not the result of different risk factors. The main arguments fo...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03044604
更新日期:1998-05-01 00:00:00
abstract::There is only a limited number of studies available comparing the effectiveness of various combinations of anti-ischemic and antianginal substances in the same patients with coronary artery disease and stable angina pectoris and even these are restricted to either only a few drugs or a single point in time for testing...
journal_title:Herz
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-12-01 00:00:00
abstract::Primary tumors of the great vessels are very rare. Primary leiomyosarcomas of the pulmonary vein are extremely rare and little is known about their clinical manifestation and treatment. We report the case of a 34-year-old patient with primary leiomyosarcoma of the pulmonary vein extending into the left atrium. A revie...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-013-3833-z
更新日期:2014-08-01 00:00:00
abstract::Patients with congenital heart disease have an increased chance to suffer from brady- as well as tachyarrhythmias. The impact of these on quality of life, morbidity and mortality is more often imperative as compared to heart-healthy individuals. The substrate for these may be either congenital or acquired. Improvement...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/BF03043882
更新日期:1999-06-01 00:00:00