[Current recommendations on echocardiographic evaluation of the severity of mitral regurgitation: standardization and practical application using a scoring system].

abstract：:Our 19th century predecessors considered the aorta as a source of cardiovascular pain associated with inflammatory aortitis, arterial hypertension, aortic aneurysms, aortic dissection, and aortic valve disease. However, during the 20th century epidemic of coronary artery disease clinicians became concerned with the sy...

journal_title：Herz

authors： Wooley CF,Sparks EH,Boudoulas H

更新日期：1999-04-01 00:00:00

abstract：:It is now generally recognized that atherosclerosis is a chronic inflammatory disease, characterized by overrecruitment of leukocytes (monocytes and T-cells) to the site of inflammation. Vascular injury in response to cardiovascular risk factors promotes endothelial dysfunction, resulting in enhanced adhesion molecule...

journal_title：Herz

authors： Steffens S,Mach F

更新日期：2004-12-01 00:00:00

abstract：:M-mode, two-dimensional and Doppler echocardiography enable evaluation of morphologic changes in valvular structures, detection of secondary changes in cardiac chambers and left ventricular function and quantification of blood flow patterns. In mitral stenosis, with M-mode echocardiography the diagnosis can be establi...

journal_title：Herz

authors： Quinones MA

更新日期：1984-08-01 00:00:00

abstract：:Surgical aortic valve replacement still represents the gold standard in patients with severe symptomatic aortic valve stenosis. In addition to conventional aortic valve replacement by mechanical or biological prostheses via a median sternotomy, novel approaches including minimally invasive strategies and new devices, ...

journal_title：Herz

authors： Liakopoulos OJ,Merkle J,Wahlers T,Choi YH

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The German national guidelines on chronic heart failure provide treatment recommendations to physicians and reflect the current level of evidence; however, it is questionable to what extent these recommendations are applied in the routine practice and what the effect of guideline adherence on mortality is. ...

journal_title：Herz

authors： Neubauer S,Schilling T,Zeidler J,Lange A,Engel S,Linder R,Verheyen F,von der Schulenburg JG,Haverich A

更新日期：2016-11-01 00:00:00

abstract：:The decision to anticoagulate patients with atrial fibrillation (AF) involves weighting the risk of an embolic event without therapy versus the risk of a hemorrhagic event on therapy. Improved methods of monitoring anticoagulation with the International Normalized Ratio (INR), and recent evidence of the efficacy and s...

journal_title：Herz

authors： Atwood JE,Albers GW

更新日期：1993-02-01 00:00:00

abstract：:As a result of an aging, increasingly obese, and decreasingly physically active population, the global incidence and prevalence of type 2 diabetes mellitus (DM) is increasing. While little can be done to influence the contribution of aging to the increasing global prevalence of diabetes, opportunities abound to develo...

journal_title：Herz

authors： Berry J,Keebler ME,McGuire DK

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The prognostic importance of high-sensitivity cardiac troponin T (hs-cTnT) has recently been reported in patients with heart failure. The myocardial performance index (MPI), which combines parameters of both systolic and diastolic ventricular function, provides a better marker of left ventricular dysfunction...

journal_title：Herz

authors： Kaypakli O,Gür M,Gözükara MY,Uçar H,Kivrak A,Şeker T,Şahin DY,Elbasan Z,Türkoğlu C,Çayli M

更新日期：2015-11-01 00:00:00

abstract：:While there is generell agreement that patients with aortic stenosis (AS) who have already developed symptoms, such as exertional dyspnea, angina or dizziness and syncope, require urgent surgery because of their otherwise very poor outcome, the management of asymptomatic severe AS remains controversial. Although preve...

journal_title：Herz

authors： Baumgartner H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:In the present study, the electropharmacological activity of traditional Chinese medicine, Ginkgo biloba extract (GBE), on human hyperpolarization-activated nucleotide-gated (HCN) channels and the underlying "funny" currents was investigated. METHODS:Standard two-electrode voltage-clamp recordings were empl...

journal_title：Herz

authors： Chen H,Chen Y,Yang J,Wu P,Wang X,Huang C

更新日期：2020-05-20 00:00:00

abstract：:Independent of the underlying cause, pulmonary hypertension (PH) remains a devastating condition that is characterized by limited survival. Cumulating evidence indicates that in addition to a dysbalance of mediators regulating vascular tone and growth factors promoting vascular remodeling, failure to resolve inflammat...

journal_title：Herz

authors： Berghausen EM,Feik L,Zierden M,Vantler M,Rosenkranz S

更新日期：2019-04-01 00:00:00

abstract：:The aortic valve consists of three cusps attached to the wall of the aortic root. During the cardiac cycle, the aortic root undergoes complex movements that precede and aid opening and closing of the aortic valve. The aortic valve cusps themselves form thin-walled pocket-like structures, made from specialized tissue w...

journal_title：Herz

authors： Bechtel JF,Erasmi AW,Misfeld M,Sievers HH

更新日期：2006-08-01 00:00:00

abstract：:In the past decade, thrombolytic therapy has become standard treatment of acute myocardial infarction. When the importance of thrombosis in the pathogenesis of acute infarction was fully recognised, several plasminogen activators were developed, streptokinase, urokinase, recombinant tissue-type plasminogen activator (...

journal_title：Herz

authors： Rutsch W,Schmutzler H

更新日期：1994-12-01 00:00:00

abstract：:The standardized and constant fixed-dose rate, no necessity for a close and regular blood monitoring as well as the small number of interactions with other drugs and daily food make therapy with the new oral anticoagulants dabigatran and rivaroxaban and in future presumably apixaban much easier and more feasible than ...

journal_title：Herz

authors： Osterspey A,Krome A

更新日期：2012-06-01 00:00:00

abstract：:Chronic ischemic heart disease patients are already being treated worldwide with bone marrow stem cells both in the context of clinical studies and in therapy trials. By combining this therapy with established revascularization procedures such as bypass surgery, a high level of patient safety can be achieved. To date,...

journal_title：Herz

authors： Kaminski A,Donndorf P,Klopsch C,Steinhoff G

更新日期：2010-08-01 00:00:00

abstract：:The case presented here is intended to raise awareness of two uncommon coronary angiographic findings in the clinical context of acute coronary syndrome. The prevalence of patients presenting with spontaneous coronary dissection as the underlying cause of an ST-elevation myocardial infarction is low. It is typically f...

journal_title：Herz

authors： Hofmann U,Schanzenbächer P

更新日期：2012-05-01 00:00:00

abstract：:During the last decade, epigenetics became one of the fastest growing research fields in numerous clinical and basic science disciplines. Evidence suggests that chromatin modifications (e.g., histone modifications and DNA methylation) as well as the expression of micro-RNA molecules play a crucial role in the pathogen...

journal_title：Herz

authors： Zimmer P,Bloch W

更新日期：2015-05-01 00:00:00

abstract：:Although rarely reported, acute instent thrombosis can be life threatening, especially in cases where there are no ST segment changes. For this reason, careful history taking, follow-up, and prompt coronary angiography may be lifesaving. Herein, a case of acute stent thrombosis with no ST segment changes on electrocar...

journal_title：Herz

authors： Canpolat U,Sunman H,Yorgun H,Atalar E

更新日期：2012-05-01 00:00:00

abstract：:Venous disease of the lower extremities comprises several common conditions such as varicose veins, superficial thrombophlebitis, deep venous thrombosis and chronic venous insufficiency. The high prevalence and increasing incidence with age of these disorders impose relevant diagnostic and therapeutic concerns. Varico...

journal_title：Herz

authors： Do DD,Husmann M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...

journal_title：Herz

authors： Brilla CG,Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:: Drug-eluting stents (DES) have been shown to reduce the risk of in-stent stenosis, one of the major problems of percutaneous coronary intervention (PCI) with implantation of baremetal stents. DES are approved in Germany since 2002. The following study is based on data of the ALKK PCI registry a...

journal_title：Herz

authors： Klein B,Zahn R,Heer T,Hochadel M,Tebbe U,Darius H,Kerber S,Schumacher B,Grube E,Hauptmann KE,Glunz HG,Senges J,Zeymer U

更新日期：2008-09-01 00:00:00

abstract：:Routine determination of troponin levels is recommended for all patients with acute ischemic stroke. In 20-55% of these patients the troponin levels are elevated, which may be caused by ischemic as well as non-ischemic myocardial damage and particularly neurocardiogenic myocardial damage. In patients with acute ischem...

journal_title：Herz

authors： Kruska M,Fastner C,Scheitz JF,Kolb A,Rutsch M,Papavassiliu T,Borggrefe M,Alonso A,Akin I,Szabo K,Baumann S

更新日期：2020-07-06 00:00:00

abstract：OBJECTIVE:Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS:We performed CMR in 30 myocardial infarction (M...

journal_title：Herz

authors： Sun W,Sun L,Yang F,Zhao X,Cai R,Yuan W

更新日期：2019-12-01 00:00:00

abstract：:The post-cardiac transplantation patient is frequently debilitated as a result of "end-stage" heart disease and typically demonstrates muscle wasting, with a reduced work capacity, maximum heart rate and peak oxygen uptake. At submaximal effort perceived exertion and ventilation are higher, and the absolute ventilator...

journal_title：Herz

authors： Kavanagh T

更新日期：1991-08-01 00:00:00

abstract：:Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator. The major hemodynamic effect of hydralazine in patients with heart failure are increased cardiac output and stroke volume, and decreased vascular resistance without any significant change in pulmonary and systemic venous pressure. Hydralazine als...

journal_title：Herz

authors： Chatterjee K

更新日期：1983-08-01 00:00:00

abstract：:The experimental and early clinical experience with percutaneous valvuloplasty using trefoil and bifoil balloon catheters (Schneider Shiley) and a long introducer sheath with a new back-up wire are reported. The trefoil balloon consists of three and the bifoil balloon of two angioplasty balloons mounted in parallel on...

journal_title：Herz

authors： Meier B,Friedli B,von Segesser L

更新日期：1988-02-01 00:00:00

abstract：:During recent years, experimental data have collected convincing evidence for the fatal interaction of myocardial ischemia, ventricular tachyarrhythmias, and sudden cardiac death. In the clinical setting, data reporting on the daily relevance of such a fatal interaction lacked until recently. However, there is now inc...

journal_title：Herz

authors： Zehender M,Faber T,Meinertz T,Just H

更新日期：1995-06-01 00:00:00

abstract：:In the clinical management of patients with valvular heart disease, transthoracic echocardiography (TTE) combined with Doppler has become the central diagnostic tool during the past decades. The development of transesophageal echocardiography (TEE) has led to an improved image quality especially of structures distant ...

journal_title：Herz

authors： Niedermeyer J,Daniel WG

更新日期：1993-12-01 00:00:00

abstract：:Cardiac surgery in patients with chronic pulmonary diseases carries a high risk of postoperative pulmonary complications (ppc) because both are known to cause ppc. Autopsy studies have revealed ppc as the main cause of mortality in approximately 5-8% of patients after cardiac surgery. Not all pulmonary diseases are hi...

journal_title：Herz

authors： Fistera D,Steveling H,Koch A,Teschler H

更新日期：2014-02-01 00:00:00

abstract：:Interventional catheterization for congenital heart disease has rapidly developed over the last 2 decades. The role of interventions has evolved from replacing surgery altogether in some cases to complementing surgery in others. The most commonly used approaches to common cardiac lesions such as persistent arterial du...

journal_title：Herz

authors： Krasemann T

更新日期：2008-12-01 00:00:00