Abstract:
BACKGROUND:The prognostic importance of high-sensitivity cardiac troponin T (hs-cTnT) has recently been reported in patients with heart failure. The myocardial performance index (MPI), which combines parameters of both systolic and diastolic ventricular function, provides a better marker of left ventricular dysfunction in hypertensive patients with preserved left ventricular ejection fraction (LVEF). AIM:We aimed to investigate the relationship between hs-cTnT and tissue Doppler-derived MPI in newly diagnosed hypertensive patients with preserved LVEF. METHODS:We studied 306 patients with newly diagnosed hypertension. The patients were divided into two groups according to their median MPI values: MPIlo and MPIhigh groups. The MPI was calculated from the pulsed-wave Doppler recordings. Left ventricular mass index (LVMI) was determined according to the Devereux formula. hs-cTnT, uric acid, and high-sensitivity C-reactive protein (hs-CRP) levels were measured in all patients. RESULTS:Hs-cTnT, hs-CRP, and uric acid levels were higher in the MPIhigh group compared with the MPIlow group (p < 0.05, for all). The LVMI values in the MPIhigh group were higher than in the MPIlow group (p < 0.05). MPI was independently associated with age, uric acid, hs-cTnT, and LVMI in multivariate analysis. Multivariate logistic regression analysis showed that MPI and LVMI were independent predictors of high hs-cTnT level in newly diagnosed hypertensive patients with preserved LVEF. CONCLUSION:Hs-cTnT was independently associated with LV dysfunction and LV hypertrophy assessed with MPI in newly diagnosed hypertensive patients.
journal_name
Herzjournal_title
Herzauthors
Kaypakli O,Gür M,Gözükara MY,Uçar H,Kivrak A,Şeker T,Şahin DY,Elbasan Z,Türkoğlu C,Çayli Mdoi
10.1007/s00059-015-4322-3subject
Has Abstractpub_date
2015-11-01 00:00:00pages
1004-10issue
7eissn
0340-9937issn
1615-6692pii
10.1007/s00059-015-4322-3journal_volume
40pub_type
杂志文章相关文献
HERZ文献大全abstract::The experimental and early clinical experience with percutaneous valvuloplasty using trefoil and bifoil balloon catheters (Schneider Shiley) and a long introducer sheath with a new back-up wire are reported. The trefoil balloon consists of three and the bifoil balloon of two angioplasty balloons mounted in parallel on...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::Remodelling is the adaptive or maladaptive response to cardiac overload or injury resulting in changes of size and function of the heart. The final pathway of maladaptive or adverse cardiac remodelling is the evolution of heart failure or sudden cardiac death. In coronary artery disease, ischemic injury leads to chang...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3660-7
更新日期:2012-09-01 00:00:00
abstract::M-mode, two-dimensional and Doppler echocardiography enable evaluation of morphologic changes in valvular structures, detection of secondary changes in cardiac chambers and left ventricular function and quantification of blood flow patterns. In mitral stenosis, with M-mode echocardiography the diagnosis can be establi...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract::Nitrates have been periodically controversial since their introduction in 1867 as a treatment for angina pectoris. The goal of this synopsis is to delineate the special and unchanged high ranking of nitrates in the treatment of angina pectoris with particular consideration to the dosage and dosage intervals. The anti-...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cardiac troponins have shown to be specific markers of myocardial injury. The aim of this prospective study was to compare patterns and kinetics of troponin I and T after coronary artery bypass grafting (CABG) with or without perioperative myocardial infarction (PMI). PATIENTS AND METHODS:119 pa...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:10.1007/s00059-004-2543-y
更新日期:2004-11-01 00:00:00
abstract::Sudden cardiac death and chronic heart failure are among the main contributors to persisting high mortality rates in Germany. In addition to removal of causal factors and guideline-conform pharmacological therapy, therapy with cardiac implantable electronic devices (CIED) is of undisputed importance. Subcutaneous defi...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-017-4548-3
更新日期:2017-04-01 00:00:00
abstract::Adequate skin perfusion is one of the most important prerequisites for healing of trophic lesions and amputation wounds in patients with peripheral arterial disease. The discrepancies possible between macro- and microcirculations stress the necessity of new methods for assessment of terminal vascular beds. With laser-...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1988-12-01 00:00:00
abstract::This review summarizes some information on the management of diabetic patients at risk for or with already established coronary artery disease. Improved knowledge among diabetologists regarding treatment and prevention of cardiovascular complications and among cardiologists regarding diabetology is a prerequisite for ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-008-3105-5
更新日期:2008-04-01 00:00:00
abstract::We report the case of a 28-year old asthmatic female patient, who developed an acute heart failure beginning with diarrhea, fever, and dyspnea 5 weeks after delivery. After improvement of all vital functions and dismissal from hospital care unit a marked blood hypereosinophilia, left ventricular congestive heart failu...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:The differential diagnosis of pericardial effusion is often challenging because different etiologies can be discussed. Of particular therapeutic and prognostic importance is the definitive differentiation of malignant pericardial effusion from benign effusions. The definitive diagnosis of malignant pericardi...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-011-3451-6
更新日期:2011-06-01 00:00:00
abstract::Following surgical correction of chronic aortic regurgitation, left ventricular (LV) volume falls to normal or near normal in most patients; this change generally occurs within the first week after surgery. During the ensuing six months, a significant regression of LV hypertrophy occurs, but most patients do not achie...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:BACKGROUND:In the present study, the electropharmacological activity of traditional Chinese medicine, Ginkgo biloba extract (GBE), on human hyperpolarization-activated nucleotide-gated (HCN) channels and the underlying "funny" currents was investigated. METHODS:Standard two-electrode voltage-clamp recordings were empl...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-020-04933-z
更新日期:2020-05-20 00:00:00
abstract::Based on the epidemiologic data of the Framingham heart study, arterial hypertension and coronary artery disease are the most frequent etiologic factors for the development of heart failure. In the pressure overloaded heart, hypertrophic growth of the myocardium includes the enlargement of cardiac myocytes stimulated ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::Left ventricular function was assessed in 38 patients two to six days after acute myocardial infarction using nuclear angiocardiography and the following parameters were measured: Left ventricular end-diastolic (LVEDV) and end-systolic volumes (LVESV), ejection fraction (LVEF), indices of left ventricular filling and ...
journal_title:Herz
pub_type: 杂志文章
doi:
更新日期:1986-06-01 00:00:00
abstract::Routine determination of troponin levels is recommended for all patients with acute ischemic stroke. In 20-55% of these patients the troponin levels are elevated, which may be caused by ischemic as well as non-ischemic myocardial damage and particularly neurocardiogenic myocardial damage. In patients with acute ischem...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-020-04967-3
更新日期:2020-07-06 00:00:00
abstract::Magnetic resonance imaging (MRI) has a number of characteristics which make it attractive for guidance of intravascular therapeutic procedures, including high soft tissue contrast, imaging in any arbitrary oblique plane, lack of ionizing radiation, and the ability to provide functional information, such as flow veloci...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s000590050036
更新日期:2000-06-01 00:00:00
abstract::The prevalence of overweight and obesity in children and adolescents is increasing. In Germany, 10-20% of children and youth are overweight and obese. Childhood obesity is associated with cardiovascular and other comorbidities. 25% suffer from arterial hypertension and/or hypercholesterolemia, 1% from diabetes mellitu...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-006-2860-4
更新日期:2006-09-01 00:00:00
abstract::Disorders of the autonomic nervous control mechanisms of heart rate and vascular tone may cause syncope. Notably these are carotid sinus and vasovagal syndromes. Knowledge of their aetiology is limited. Each presents cardioinhibition and vasodepression. Pacing offers benefit in cardioinhibition and the mode required i...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1993-06-01 00:00:00
abstract::A Monte Carlo simulation model is presented which allows an assessment of the costs for coronary heart disease (CHD) (from a social security perspective) to be made over a time interval of 10 years. The difference between a CHD population and a normal population is calculated whereby the CHD population corresponds in ...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/pl00001964
更新日期:2000-08-01 00:00:00
abstract::The presence of intraventricular obstruction is a powerful predictor of outcome in patients with hypertrophic cardiomyopathy (HCM) and, when associated with severe, drug-refractory symptoms, should be managed aggressively. Resting left ventricular outflow obstruction is found in approximately 20% of the patients, clas...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-006-2928-1
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:: Drug-eluting stents (DES) have been shown to reduce the risk of in-stent stenosis, one of the major problems of percutaneous coronary intervention (PCI) with implantation of baremetal stents. DES are approved in Germany since 2002. The following study is based on data of the ALKK PCI registry a...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-008-3097-1
更新日期:2008-09-01 00:00:00
abstract::Drug-eluting stents (DESs) have dramatically reduced the rates of in-stent restenosis compared with those of bare-metal stents. DES placement is frequently followed by high-pressure postdilatation to prevent incomplete stent apposition that may cause a further stent fracture (SF). SF may remain asymptomatic but it is ...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-013-3947-3
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:The progression of coronary atherosclerosis is determined by risk factor exposure. It is also an important predictor of future cardiac events in its own right. Coronary calcium represents an integral part of coronary atherosclerosis. Accurate measurements can be obtained by using electron-beam computed tomog...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/pl00002031
更新日期:2001-06-01 00:00:00
abstract::Interventional catheterization for congenital heart disease has rapidly developed over the last 2 decades. The role of interventions has evolved from replacing surgery altogether in some cases to complementing surgery in others. The most commonly used approaches to common cardiac lesions such as persistent arterial du...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-008-3133-1
更新日期:2008-12-01 00:00:00
abstract::In a prospective double-blind study of 40 male patients requiring aorto-coronary bypass surgery, a dose of 8 ng/kg/min of PGI2 was infused throughout extracorporeal circulation (ECC) (control group: glycine buffer). Between the two treatment groups there was no difference in preoperative hemodynamic parameters, number...
journal_title:Herz
pub_type: 临床试验,杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::The post-cardiac transplantation patient is frequently debilitated as a result of "end-stage" heart disease and typically demonstrates muscle wasting, with a reduced work capacity, maximum heart rate and peak oxygen uptake. At submaximal effort perceived exertion and ventilation are higher, and the absolute ventilator...
journal_title:Herz
pub_type: 杂志文章,评审
doi:
更新日期:1991-08-01 00:00:00
abstract::Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia with a prevalence of 0.5-10%, depending predominantly on age. The arrhythmia is associated with significant morbidity and mortality, mainly due to thromboembolic events including stroke and systemic embolisms. These complications can be e...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-017-4648-0
更新日期:2018-02-01 00:00:00
abstract::Atrial fibrillation (AF) is currently one of the major causes of ischemic stroke with an estimated stroke risk of 5% per year. Oral anticoagulation is an effective treatment for the reduction of stroke risk in patients with AF but is also associated with an increased risk of bleeding. In patients with AF it has been s...
journal_title:Herz
pub_type: 杂志文章,评审
doi:10.1007/s00059-014-4198-7
更新日期:2015-02-01 00:00:00
abstract::While there is general agreement on the favorable impact of immunosuppression in eosinophilic, granulomatous, giant cell and lymphocytic myocarditis and with inflammatory myocardial disease associated with connective tissue disorders or with rejection of a transplanted heart, its therapeutic role in the treatment of l...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-012-3694-x
更新日期:2012-12-01 00:00:00
abstract::We present a case of severe congestive left heart failure due to profound and long-term hypocalcemia caused by surgically induced hypoparathyroidism. Hypocalcemia as a potential contributor to heart failure should be included in the differential diagnosis of all patients with congestive heart failure who do not respon...
journal_title:Herz
pub_type: 杂志文章
doi:10.1007/s00059-010-3374-7
更新日期:2010-10-01 00:00:00