Acute stent thrombosis during percutaneous coronary intervention. Treatment with tirofiban.

abstract：:Direct inhibition of thrombin is a promising new strategy for the treatment of cardiovascular disease and thrombosis. Three intravenous (lepirudin, bivalirudin and argatroban) and one oral direct thrombin inhibitor (ximelagatran) are currently available and approved for some clinical indications in the treatment of ca...

journal_title：Herz

authors： Ahrens I,Bode C

更新日期：2005-05-01 00:00:00

abstract：:Despite all advances in the diagnostic and therapy of cardiovascular diseases the mortality from malignant ventricular tachyarrhythmias is still a major health problem. In addition to established therapeutic strategies in the prevention of sudden cardiac death such as antiarrhythmic drug treatment, catheter ablation o...

journal_title：Herz

authors： Neuzner J,Pitschner HF,Schlepper M

更新日期：1994-10-01 00:00:00

abstract：:Unexplained sudden death in the young is cardiovascular in most cases. Structural and conduction defects in cardiac-related genes can conspire to underlie sudden cardiac death. Here we report a clinical investigation and an extensive genetic assessment of a Tunisian family with sudden cardiac death in young members. I...

journal_title：Herz

authors： Jaouadi H,Bouyacoub Y,Chabrak S,Kraoua L,Zaroui A,Elouej S,Nagara M,Dallali H,Delague V,Levy N,Benkhalifa R,Mechmeche R,Zaffran S,Abdelhak S

更新日期：2020-01-22 00:00:00

abstract：:Heart failure remains a frequent cause of death and is the leading reason for hospitalization in Germany although therapeutic options have significantly increased over the past years particularly in heart failure with reduced ejection fraction. Clinical symptoms are usually preceded by cardiac remodeling, which was or...

journal_title：Herz

authors： Ertl G,Brenner S,Angermann CE

更新日期：2017-02-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) using a balloon-expandable valve has been developed by the authors' group 7 years ago to offer a therapeutic solution to nonoperable or surgical high-risk patients with degenerative aortic stenosis. The technique and the devices used have rapidly evolved thereafter and TA...

journal_title：Herz

authors： Cribier A,Litzler PY,Eltchaninoff H,Godin M,Tron C,Bauer F,Bessou JP

更新日期：2009-08-01 00:00:00

abstract：:Drug-eluting stents (DESs) have dramatically reduced the rates of in-stent restenosis compared with those of bare-metal stents. DES placement is frequently followed by high-pressure postdilatation to prevent incomplete stent apposition that may cause a further stent fracture (SF). SF may remain asymptomatic but it is ...

journal_title：Herz

authors： Acar RD,Bulut M,Akcakoyun M

更新日期：2015-05-01 00:00:00

abstract：:Since the first comprehensive computerized videometric systems for quantitative assessment of the dynamic morphology and function of the heart have been developed, angiocardiographic image generation and computer aided evaluation have improved considerably. As a second method for morphological imaging echocardiography...

journal_title：Herz

authors： Onnasch DG

更新日期：1985-08-01 00:00:00

abstract：:Lipid disorders play an essential role in the pathogenesis of atherosclerotic diseases. An integral part of the clinical evaluation is the estimation of the individual cardiovascular risk using risk scores and patient history. Due to the long established prognostic relevance, reduction of low-density lipoproteins (LDL...

journal_title：Herz

authors： Custodis F,Laufs U

更新日期：2014-02-01 00:00:00

abstract：:Genetic testing plays an increasing role in cardiovascular medicine. Advances in technology and the development of novel and more affordable (high throughput) methods have led to the identification of genetic risk factors in research and clinical practice. Also, this progress has simplified the screening of patients a...

journal_title：Herz

authors： Trenkwalder T,Kessler T,Schunkert H

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Saphenous vein graft disease (SVGD) after by-pass surgery is an important cause of morbidity and mortality for patients with coronary artery disease. Comprehensive evaluation of biochemical and hematological parameters associated with this problem is limited. Plateletcrit (PCT) provides complete information ...

journal_title：Herz

authors： Akpinar I,Sayin MR,Gursoy YC,Karabag T,Kucuk E,Buyukuysal MC,Aydin M,Haznedaroglu IC

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cardiac troponins have shown to be specific markers of myocardial injury. The aim of this prospective study was to compare patterns and kinetics of troponin I and T after coronary artery bypass grafting (CABG) with or without perioperative myocardial infarction (PMI). PATIENTS AND METHODS:119 pa...

journal_title：Herz

authors： Peivandi AA,Dahm M,Opfermann UT,Peetz D,Doerr F,Loos A,Oelert H

更新日期：2004-11-01 00:00:00

abstract：:Doxorubicin is an effective anti-tumor agent with a cumulative dose-dependent cardiotoxicity. In addition to its principal toxic mechanisms involving iron and redox reactions, recent studies have described new mechanisms of doxorubicin-induced cell death, including abnormal protein processing, hyper-activated innate i...

journal_title：Herz

authors： Shi Y,Moon M,Dawood S,McManus B,Liu PP

更新日期：2011-06-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia with a prevalence of 0.5-10%, depending predominantly on age. The arrhythmia is associated with significant morbidity and mortality, mainly due to thromboembolic events including stroke and systemic embolisms. These complications can be e...

journal_title：Herz

authors： Erath JW,Hohnloser SH

更新日期：2018-02-01 00:00:00

abstract：:During recent years, experimental data have collected convincing evidence for the fatal interaction of myocardial ischemia, ventricular tachyarrhythmias, and sudden cardiac death. In the clinical setting, data reporting on the daily relevance of such a fatal interaction lacked until recently. However, there is now inc...

journal_title：Herz

authors： Zehender M,Faber T,Meinertz T,Just H

更新日期：1995-06-01 00:00:00

abstract：:The present data demonstrate clinical feasibility of intracoronary beta brachytherapy and fail to reveal any complications that could be attributed to it. Definitive conclusions regarding safety will have to await longer term evaluation. Proof of efficacy will require strict dose finding evaluation of higher doses tha...

journal_title：Herz

authors： Verin V,Popowski Y

更新日期：1998-09-01 00:00:00

abstract：:Sudden cardiac death and chronic heart failure are among the main contributors to persisting high mortality rates in Germany. In addition to removal of causal factors and guideline-conform pharmacological therapy, therapy with cardiac implantable electronic devices (CIED) is of undisputed importance. Subcutaneous defi...

journal_title：Herz

authors： Kuschyk J,Rudic B,Borggrefe M,Akin I

更新日期：2017-04-01 00:00:00

abstract：:Myocardial remodeling comprises changes in cardiac shape, mass, diameter, and function in response to changes in hemodynamic load, cardiac damage, or neurohumoral stimulation. Adaptive remodeling is a consequence of physiological stimuli such as physical activity. Maladaptive remodeling results from pathologic conditi...

journal_title：Herz

authors： Werner C,Fürster T,Laufs U

更新日期：2012-02-01 00:00:00

abstract：:According to the current guidelines coronary revascularization in acute coronary syndromes (ACS) is primarily performed by percutaneous coronary interventions (PCI). However, in several scenarios like complex coronary pathologies, unsuccessful PCI, complicated PCI or cardiogenic shock, surgical coronary revascularizat...

journal_title：Herz

authors： Rastan AJ,Thiele H,Schuler G,Mohr FW

更新日期：2010-03-01 00:00:00

abstract：:The endothelium, the monolayer covering the inner surface of blood vessels, plays a pivotal role in the regulation of vascular tone and structure, as well as vascular inflammation and thrombosis, i.e., of key events of the atherosclerotic disease process and its clinical complications, such as myocardial infarction an...

journal_title：Herz

authors： Giannotti G,Landmesser U

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:In addition to the genetic complexity of hypertrophic cardiomyopathy (HCM), there must be other disease-modifying factors that contribute to its highly variable clinical and phenotypic expression. The authors aimed to investigate serum thiol/disulphide homeostasis as a proxy for oxidative stress using a nove...

journal_title：Herz

authors： Sari M,Erkorkmaz U,Yazar H,Kocayigit I,Omar B,Alizade E,Aksoy MNM,Uslu A,Cakar GC,Pala S

更新日期：2019-12-09 00:00:00

abstract：:The diagnosis of varicose veins is based on historical details pertaining to risk factors such as familial preponderance, advanced age, overweight, multiple births, professional activities carried out mainly in the standing or sitting position, use of oral contraceptives, diuretics or drugs which lower venous tone. Sw...

journal_title：Herz

authors： Hauer G

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS:We performed CMR in 30 myocardial infarction (M...

journal_title：Herz

authors： Sun W,Sun L,Yang F,Zhao X,Cai R,Yuan W

更新日期：2019-12-01 00:00:00

abstract：:Interventional treatment of mitral insufficiency has recently become possible on a limited basis. The developed percutaneous procedures aim at minimizing the trauma in high-risk surgical candidates. Echocardiography has a major role in the preinterventional evaluation, during the interventional procedure, and in the p...

journal_title：Herz

authors： Hoffmann R,Altiok E

更新日期：2009-09-01 00:00:00

abstract：:Adequate skin perfusion is one of the most important prerequisites for healing of trophic lesions and amputation wounds in patients with peripheral arterial disease. The discrepancies possible between macro- and microcirculations stress the necessity of new methods for assessment of terminal vascular beds. With laser-...

journal_title：Herz

authors： Ranft J

更新日期：1988-12-01 00:00:00

abstract：:The decision to anticoagulate patients with atrial fibrillation (AF) involves weighting the risk of an embolic event without therapy versus the risk of a hemorrhagic event on therapy. Improved methods of monitoring anticoagulation with the International Normalized Ratio (INR), and recent evidence of the efficacy and s...

journal_title：Herz

authors： Atwood JE,Albers GW

更新日期：1993-02-01 00:00:00

abstract：:Coronary artery disease (CAD) is a leading cause of morbidity and mortality in western countries and is of significant socio-economic importance due to its increasing prevalence. Until percutaneous coronary interventions (PCI) were established, CAD could only be treated by surgical revascularization or pharmacological...

journal_title：Herz

authors： Möllmann H,Szardien S,Kempfert J,Nef H,Liebetrau C,Walther T,Hamm C

更新日期：2013-08-01 00:00:00

abstract：:The therapy of patients with syncope is oriented to the underlying pathophysiological mechanisms. Patients with reflex syncope require careful education regarding recognition of warning signs and the avoidance of trigger factors. Treatment with beta blockers is nowadays obsolete. Even other drugs have failed to show a...

journal_title：Herz

authors： Andresen D

更新日期：2014-06-01 00:00:00

abstract：:Diabetes is associated with the development of premature cardiovascular disease (CVD), which relates to the clustering of risk factors such as dyslipidaemia, hypertension, obesity and hyperglycaemia in the presence of insulin resistance. In addition, diabetes is associated with an inflammatory and pro-thrombotic envir...

journal_title：Herz

authors： King RJ,Grant PJ

更新日期：2016-05-01 00:00:00

abstract：:In 190 patients, 208 "screw-in" type pacemaker leads were implanted; 147 in the right ventricle and 61 in the right atrium. There was no significant difference in the time required for atrial (54.7 +/- 19 min) or ventricular fixation (56.0 +/- 25 min). Similarly, fluoroscopy times for both atrial (6.3 +/- 4 min) and v...

journal_title：Herz

authors： Machraoui A,Schött D,Ong TS,Straub H,Jaedicke W,Barmeyer J

更新日期：1981-12-01 00:00:00

abstract：:Cardiovascular (CV) risk assessment is based on the utilization of risk scores, enabling clinicians to estimate an individual's risk to develop CV pathologies and events. Such risk scores comprise classic CV risk factors such as smoking, diabetes, hypertension, and blood cholesterol levels. Recently, other CV biomarke...

journal_title：Herz

authors： Schulte C,Zeller T

更新日期：2020-02-01 00:00:00