Endothelial dysfunction as an early sign of atherosclerosis.

abstract：BACKGROUND:Inducible nitric oxide synthase (iNOS) single-nucleotide polymorphisms have been reported to confer susceptibility to hypertension, but no consensus has been reached. The aim of this study was to investigate the association between iNOS and hypertension in a Chinese population. METHODS:This was a case-contr...

journal_title：Herz

authors： Zhai Z,Wang Z,Wang L,Chen S,Ren H,Wang D

更新日期：2018-08-01 00:00:00

abstract：:The rapid increase of morbid obesity has become an important task in the Western world in recent years. Since conservative treatments have failed to prove sufficient efficacy, surgery has turned out to be the most powerful option in treating morbid obesity. In this paper, the different surgical techniques with their a...

journal_title：Herz

authors： Wildi S,Müller MK,Clavien PA,Weber M

更新日期：2006-05-01 00:00:00

abstract：:Cardiac surgery in patients with chronic pulmonary diseases carries a high risk of postoperative pulmonary complications (ppc) because both are known to cause ppc. Autopsy studies have revealed ppc as the main cause of mortality in approximately 5-8% of patients after cardiac surgery. Not all pulmonary diseases are hi...

journal_title：Herz

authors： Fistera D,Steveling H,Koch A,Teschler H

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:One crucial goal of magnetic resonance imaging (MRI) in patients with coronary artery disease (CAD) is the characterization of myocardial microcirculation that reflects tissue supply much better than detection and quantification of a stenosis itself. PERFUSION: Myocardial perfusion is one important paramet...

journal_title：Herz

authors： Wacker CM,Bauer WR

更新日期：2003-03-01 00:00:00

abstract：:Besides diagnosis of the mechanism of mitral regurgitation accurate evaluation of the severity is of critical importance for the assessment of prognosis and planning of therapy. Current recommendations are differentiating two levels of evaluation of severity, (1) a rapid, basic evaluation, and (2) an extended, quantit...

journal_title：Herz

authors： Buck T,Plicht B,Erbel R

更新日期：2006-02-01 00:00:00

abstract：:During recent years, experimental data have collected convincing evidence for the fatal interaction of myocardial ischemia, ventricular tachyarrhythmias, and sudden cardiac death. In the clinical setting, data reporting on the daily relevance of such a fatal interaction lacked until recently. However, there is now inc...

journal_title：Herz

authors： Zehender M,Faber T,Meinertz T,Just H

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:The Braunwald classification and TIMI (Thrombolysis In Myocardial Infarction) risk score are used to stratify cardiovascular risk in patients with unstable angina (UA). However, these scores have a limited capacity in the practice of cardiology. OBJECTIVES:This study sought to develop a new score, based on ...

journal_title：Herz

authors： Xia Y,Xia Y,Xu K,Ma Y,Pan D,Xu T,Lu L,Li D

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is involved in various aspects of vascular biology and different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization domain-containing protein (NOD) 2, a pivotal innate immune receptor for muramyl dipeptide (MDP), has been reported to be a central regulator in...

journal_title：Herz

authors： Kong LJ,Wang YN,Wang Z,Lv QZ

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Unstable angina accounts for more than one million hospital admissions annually. 6-8% of patients with this condition have non-fatal myocardial infarction or die within the first year after diagnosis. Recently, the term "acute coronary syndromes" has been used to describe the spectrum of conditions that incl...

journal_title：Herz

authors： Auer J,Berent R,Maurer E,Mayr H,Weber T,Eber B

更新日期：2001-03-01 00:00:00

abstract：:In congestive heart failure (CHF), even today, pharmacotherapy renders primarily only symptomatic improvement. The success of the treatment is basically dependent on the degree of functional myocardial impairment, that is, the condition of the inadequately treatable underlying disease. Treatment should be differential...

journal_title：Herz

authors： Thormann J,Kramer W,Dieterich HA

更新日期：1990-06-01 00:00:00

abstract：:One of the most important treatment principles in interventional cardiology relies on myocardial revascularization by percutaneous coronary intervention (PCI) or surgical placement of coronary artery bypass grafts (CABG). However, in order to apply these principles effectively, it is important to identify patients who...

journal_title：Herz

authors： Nef H,Renker M,Hamm CW,European Society of Cardiology.,European Association for Cardio-thoracic Surgery.

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...

journal_title：Herz

authors： Brilla CG,Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：:Although viral myocarditis has been mostly attributed to enterovirus and adenovirus infection until recently, the association with parvovirus B19 in Europe and hepatitis C virus in Asia has lately been noted. Clinical trials of antiviral agents, such as interferons, are in progress. Whereas immunosuppression with cort...

journal_title：Herz

authors： Matsumori A

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Takotsubo cardiomyopathy (TTC) is a transient left ventricular (LV) dysfunction that predominantly affects older women and has three main variants: apical, mid-ventricular, and basal. The recurrence rate of TTC is roughly around 11 % at 4-year follow-up. The pathogenesis of TTC is not clear and various theor...

journal_title：Herz

authors： Singh K,Parsaik A,Singh B

更新日期：2014-12-01 00:00:00

abstract：:Blood pressure, together with proteinuria, represents one of the most important factors in the progression of chronic renal failure (CRF). Antihypertensive therapy is beneficial to slow down the progression of a variety of chronic renal diseases, no matter what the cause. Intraglomerular hypertension, increased glomer...

journal_title：Herz

authors： Wolf S,Risler T

更新日期：2004-05-01 00:00:00

abstract：:The incidence of coronary heart disease and myocardial infarction fell gradually during the seventies. Reasons for this decline are not well understood. Speculations include changes of life style and health care. However, cardiovascular disease is still the leader of mortality in Western developed countries. Mortality...

journal_title：Herz

authors： Ertl G,Gaudron P,Eilles C,Kochsiek K

更新日期：1993-12-01 00:00:00

abstract：:Lipid disorders play an essential role in the pathogenesis of atherosclerotic diseases. An integral part of the clinical evaluation is the estimation of the individual cardiovascular risk using risk scores and patient history. Due to the long established prognostic relevance, reduction of low-density lipoproteins (LDL...

journal_title：Herz

authors： Custodis F,Laufs U

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Cardiac involvement may precede the onset of muscular manifestations in Becker muscular dystrophy (BMD), but Wolff-Parkinson-White (WPW) syndrome has not been reported as initial cardiac manifestation of BMD. CASE STUDY:In a 43-year-old, HIV-negative male, WPW syndrome was diagnosed at age 26 years upon a r...

journal_title：Herz

authors： Finsterer J,Stöllberger C,Quasthoff S

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The beta-adrenergic receptors of the myocardium play an important role in the regulation of heart function. The beta-adrenergic receptors belong to the family of G-protein coupled receptors. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors). The receptors consist of seven membr...

journal_title：Herz

authors： Wallukat G

更新日期：2002-11-01 00:00:00

abstract：:Many electrophysiological and histological investigations have demonstrated that post-operative dysrhythmias which occur in children with heart disorders requiring extensive surgical treatment in the area of the right atrium, are often caused by intraoperative lesions of the sinoatrial node. Accordingly, accurate dete...

journal_title：Herz

authors： Henglein D,Hebel R,Schoenen J,Mendler N,Mocellin R

更新日期：1983-10-01 00:00:00

abstract：:In primary prevention, traditional risk factors are a useful first step in determining who is at cardiovascular risk, however, it has been noted that a considerable number of those at risk cannot be identified on the basis of traditional risk factors alone. Among blood biomarkers, C-reactive protein (CRP), measured by...

journal_title：Herz

authors： Karakas M,Koenig W

更新日期：2009-12-01 00:00:00

abstract：:Transcatheter procedures have been adopted as novel treatment strategy for patients with valvular heart disease, particularly for those who are inoperable or at high risk for surgical valve procedures. Significant technological advances have resulted in an improvement of devices for transcatheter aortic valve replacem...

journal_title：Herz

authors： Figulla HR,Lauten A

更新日期：2015-04-01 00:00:00

abstract：:Pulmonary arteriovenous malformations (PAVM) consist of an abnormal connection between the pulmonary artery and vein bypassing the pulmonary capillary bed. Pulmonary arteriovenous fistulae are characterized by a right-to-left shunt of variable magnitude, and they may be accompanied by other congenital anomalies. We de...

journal_title：Herz

authors： Kucukoglu MS,Sinan UY,Kilickesmez KO,Saltık IL,Dursun M,Gurmen T

更新日期：2012-08-01 00:00:00

abstract：:Eosinophilic myocarditis is caused by activation of eosinophilic granulocytes whereby there is a release of eosinophilic granules. Quite a few of the released compounds, especially eosinophilic cationic proteins, have a tissue-damaging effect also in the myocardium. Eosinophilia may be due to hypersensitivity, parasit...

journal_title：Herz

authors： Baandrup U

更新日期：2012-12-01 00:00:00

abstract：:The use of drug-eluting stents (DESs) for patients with coronary artery disease is widespread. DESs have been associated with a lower rate of repeat revascularization, death, and myocardial infarction compared with bare metal stents. However, DESs can lead to a prothrombotic environment in the coronary arteries, resul...

journal_title：Herz

authors： Liu C,Liu M,Chen D,Liu H,Jiang Q,Lu J,Zuo L

更新日期：2015-08-01 00:00:00

abstract：:The majority of sustained ventricular tachycardias are caused by a reentry mechanism. Conditions prerequisite to a reentry circuit are electrophysiological changes, namely conduction delay and block which are incurred by virtue of changes in the myocardial tissue due to scarring, ischemia or fatty infiltration and res...

journal_title：Herz

authors： Klein H,Trappe HJ,Schröder E

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:The most common cause of procedural failure in cardiac catheterization using the transradial approach is radial artery spasm. The aim of this study was to compare the procedural success rate of the 6‑Fr Glidesheath Slender with the 6‑Fr standard sheath in transradial coronary angiography and intervention. M...

journal_title：Herz

authors： Gul B,Stolar M,Stair B,Hermany P,Willis S,Mena-Hurtado C,Attaran R

更新日期：2020-02-01 00:00:00

abstract：:The 4th edition of the Universal Definition of Myocardial Infarction (MI) recommends measurement of cardiac troponin (cTn) T or I for the diagnosis of MI due to their absolute cardiac tissue specificity. In this MI definition, values exceeding the 99th percentile of a healthy reference population distinguish between d...

journal_title：Herz

authors： Giannitsis E,Gopi V

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Renal denervation (RDN) has been proposed as a novel antihypertensive intervention for treating resistant hypertension. It remains to be investigated which patient groups can potentially benefit from RDN. The present study aimed to evaluate the efficacy and safety of RDN in patients with mild-moderate resist...

journal_title：Herz

authors： Chen S,Kiuchi MG,Schmidt B,Hoye NA,Acou WJ,Liu S,Chun KRJ,Pürerfellner H

更新日期：2019-08-01 00:00:00

abstract：:Unexplained sudden death in the young is cardiovascular in most cases. Structural and conduction defects in cardiac-related genes can conspire to underlie sudden cardiac death. Here we report a clinical investigation and an extensive genetic assessment of a Tunisian family with sudden cardiac death in young members. I...

journal_title：Herz

authors： Jaouadi H,Bouyacoub Y,Chabrak S,Kraoua L,Zaroui A,Elouej S,Nagara M,Dallali H,Delague V,Levy N,Benkhalifa R,Mechmeche R,Zaffran S,Abdelhak S

更新日期：2020-01-22 00:00:00