Effectiveness of prolonged clopidogrel-based dual antiplatelet therapy after drug-eluting stent implantation: Evidence-based meta-analysis.

Abstract:

:The use of drug-eluting stents (DESs) for patients with coronary artery disease is widespread. DESs have been associated with a lower rate of repeat revascularization, death, and myocardial infarction compared with bare metal stents. However, DESs can lead to a prothrombotic environment in the coronary arteries, resulting in a higher rate of thrombotic events. To counteract this, dual-antiplatelet therapy (DAPT) consisting of aspirin and clopidogrel is recommended. Currently, there are no clear guidelines on the duration of DAPT. We therefore conducted a meta-analysis to assess the effectiveness of prolonged DAPT after DES implantation.

journal_name

Herz

journal_title

Herz

authors

Liu C,Liu M,Chen D,Liu H,Jiang Q,Lu J,Zuo L

doi

10.1007/s00059-015-4304-5

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

795-802

issue

5

eissn

0340-9937

issn

1615-6692

journal_volume

40

pub_type

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