Abstract：
:Patients with congenital heart disease have an increased chance to suffer from brady- as well as tachyarrhythmias. The impact of these on quality of life, morbidity and mortality is more often imperative as compared to heart-healthy individuals. The substrate for these may be either congenital or acquired. Improvements of the surgical management of these patients have led, on the one hand, to improved survival rates with prolonged life expectancy within the last 2 decades, which on the other hand provided the basis for a higher rate of acquired cardiac arrhythmias. Together, this not only challenges diagnostics and therapy but also the prognostic relevance of these arrhythmias. The therapeutic strategies and prognostic markers have until now mostly been based on retrospective studies limited by the low number of patients and inhomogeneous patient selection. Despite these limitations, an increased risk of sudden cardiac death has been substantiated for certain patient groups, e.g., those operated on by the Mustard- or Senning procedures in patients with transposition of the great arteries and patients operated on with correction of the tetralogy of Fallot. However, until now it has not been possible to identify reliable markers for establishing the risk on an individual basis within these patient cohorts. For achieving reliable data on the symptomatic and prognostic effects of present-day--as well as new-coming--therapeutic strategies, it is mandatory to perform prospectively based, randomized multicenter studies. Furthermore, the well-appreciated synergism of hemodynamically and primarily of arrhythmia-based effects on prognosis could potentially be divided into their relative weight to better guide appropriate, substrate-related therapy. In addition, this should help to get better estimates of the risk for sudden cardiac death in different, etiologically homogeneous, groups of patients with congenital heart disease.
journal_name
Herzjournal_title
Herzauthors
Hebe J,Krings G,Hansen P,Volkmer M,Ouyang F,Kuck KHdoi
10.1007/BF03043882keywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
315-34issue
4eissn
0340-9937issn
1615-6692journal_volume
24pub_type
杂志文章,评审相关文献
HERZ文献大全abstract：:In recent years we identified numerous cardiovascular risk factors and had been able to reduce cardiovascular events by a variety of different interventions. There is no question that we can improve the course of coronary artery disease (CAD) in patients with a high-risk profile by modifying these factors. Despite thi...
journal_title：Herz
pub_type： 临床试验,杂志文章
doi：10.1007/pl00001948
更新日期：2000-03-01 00:00:00
abstract：:Preliminary results are reported using 201Tl-myocardial scintigraphy (MSC) with quantitated analysis of redistribution kinetics immediately after ergometry (climbing step test) two to four hours later respectively and (Dual-ROI-) Equilibrium-Radionuclide-Ventriculography (ERNVG) with 99mTc-in vivo-labeled erythrocytes...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:Plasma catecholamines and hemodynamic were assessed in 32 patients with heart failure of varying degrees due to coronary artery disease as well as in twelve healthy control subjects. The studies employed the use of a (Swan-Ganz) semi-floating, balloon-tipped, thermodilution catheter during supine bicycle ergometry at ...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：BACKGROUND:Cardiac involvement in Lyme disease, caused by the tick-borne spirochete Borrelia burgdorferi, has been reported to occur in 0.3-4 % of infected patients in Europe. Cardiac manifestations may include conduction disturbances, and also myocarditis, pericarditis, and left ventricular dysfunction. We investigate...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-014-4118-x
更新日期：2015-03-01 00:00:00
abstract：:The progress in cardiology during the last 50 years can best be studied by looking at the diagnostics and treatment of patients with aortic valve stenosis. Previously, the clinical examination, electrocardiography (ECG) and chest X‑ray were used before heart catheterization, which included a transseptal puncture to co...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-020-04980-6
更新日期：2020-11-01 00:00:00
abstract：:Our 19th century predecessors considered the aorta as a source of cardiovascular pain associated with inflammatory aortitis, arterial hypertension, aortic aneurysms, aortic dissection, and aortic valve disease. However, during the 20th century epidemic of coronary artery disease clinicians became concerned with the sy...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/BF03043853
更新日期：1999-04-01 00:00:00
abstract：:In the last years several new data allow a controversial but convincing interpretation of the pathogenesis of atherosclerosis (arteriosclerosis). Atherosclerosis can be apparently the result of ultrachronic persistent infection by Chlamydia pneumoniae and not the result of different risk factors. The main arguments fo...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/BF03044604
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-003-2517-5
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:In Germany, about 6,000 pregnancies in women with grown-up congenital heart disease or acquired valvular lesions are expected per year. The pregnancy-related physiology is characterized by a 50% increase in plasma volume and a 25% increase in erythrocyte volume. The cardiac output increases by 40% due to 30%...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-003-2467-y
更新日期：2003-05-01 00:00:00
abstract：:Independent of the underlying cause, pulmonary hypertension (PH) remains a devastating condition that is characterized by limited survival. Cumulating evidence indicates that in addition to a dysbalance of mediators regulating vascular tone and growth factors promoting vascular remodeling, failure to resolve inflammat...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-019-4795-6
更新日期：2019-04-01 00:00:00
abstract：:Via the internet smartphones allow the download of applications ("Apps") that can address various requirements of daily life. These technical advances create new opportunities to better meet needs of patients suffering from hypertension. This may apply particularly for medication adherence, blood pressure control and ...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-012-3685-y
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:The most common cause of procedural failure in cardiac catheterization using the transradial approach is radial artery spasm. The aim of this study was to compare the procedural success rate of the 6‑Fr Glidesheath Slender with the 6‑Fr standard sheath in transradial coronary angiography and intervention. M...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-018-4707-1
更新日期：2020-02-01 00:00:00
abstract：:Despite great advances in the pathophysiology and etiology of myocarditis, the clinical diagnosis of myocarditis in daily clinical practise remains challenging. Often the diagnosis was not clear because of the heterogeneity of clinical symptoms and the lack of guidelines for adequate diagnostic requirements and consec...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-3988-7
更新日期：2013-12-01 00:00:00
abstract：:Recent developments in technology have stimulated interest in the use of catheter-directed laser energy for removal of atherosclerotic plaques. Over the past three years, intensive research efforts by a number of investigators have defined the potential therapeutic benefit of laser angioplasty, as well as its limitati...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:We report the case of a 28-year old asthmatic female patient, who developed an acute heart failure beginning with diarrhea, fever, and dyspnea 5 weeks after delivery. After improvement of all vital functions and dismissal from hospital care unit a marked blood hypereosinophilia, left ventricular congestive heart failu...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:Surgical aortic valve replacement still represents the gold standard in patients with severe symptomatic aortic valve stenosis. In addition to conventional aortic valve replacement by mechanical or biological prostheses via a median sternotomy, novel approaches including minimally invasive strategies and new devices, ...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-017-4593-y
更新日期：2017-09-01 00:00:00
abstract：:Formerly the term alcoholism has been defined only by alcohol-related conditions. About 20 years ago a WHO committee recommended to differentiate between alcohol abuse and alcohol dependence. The new classifications and manuals followed this proposal: Criteria for alcohol abuse are still alcohol sequelae whereas alcoh...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVE:The"no-reflow" phenomenon is associated with a worse prognosis at follow-up for patients with acute ST-segment elevation myocardial infarction (STEMI). Predicting and preventing no-reflow is therefore a crucial step in improving the prognosis of STEMI patients. The purpose of this study was to investigate the...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-4026-5
更新日期：2015-05-01 00:00:00
abstract：:Atrial fibrillation (AF) is currently one of the major causes of ischemic stroke with an estimated stroke risk of 5% per year. Oral anticoagulation is an effective treatment for the reduction of stroke risk in patients with AF but is also associated with an increased risk of bleeding. In patients with AF it has been s...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-014-4198-7
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Left ventricular inferoseptal clefts are a localized variant of myocardial structure, easily overlooked but potentially raising concern when identified through imaging. CASE STUDY:Here we illustrate and describe inferoseptal clefts by means of multimodality imaging and consider them in relation to possible ...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-011-3424-9
更新日期：2011-08-01 00:00:00
abstract：:The present data demonstrate clinical feasibility of intracoronary beta brachytherapy and fail to reveal any complications that could be attributed to it. Definitive conclusions regarding safety will have to await longer term evaluation. Proof of efficacy will require strict dose finding evaluation of higher doses tha...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/BF03043599
更新日期：1998-09-01 00:00:00
abstract：:In this investigation, we studied the feasibility of 3D-reconstruction from 2D cross-sectional intracoronary ultrasound images. A computer-aided, automated 3D-reconstruction was used to generate cylindrical and sagittal format of vessels in vitro (n = 9) and in vivo (n = 48). Ultrasound 2D-images were acquired with a ...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:Adequate skin perfusion is one of the most important prerequisites for healing of trophic lesions and amputation wounds in patients with peripheral arterial disease. The discrepancies possible between macro- and microcirculations stress the necessity of new methods for assessment of terminal vascular beds. With laser-...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1988-12-01 00:00:00
abstract：:There is a J-shaped correlation between the amount of alcohol consumed per day and overall mortality risk and an inverse correlation between the amount of alcohol consumed per day and cardiovascular mortality. The evidence is stronger for men than for women. The correlations are independent of the type of alcoholic be...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-016-4467-8
更新日期：2016-09-01 00:00:00
abstract：:In eleven patients with aortic dissection or perforated endocarditic aortic wall abscess cavity, the diagnostic usefulness of Color Doppler Echocardiography (CDE) for the identification of true and false lumen as well as the perforation jet was assessed by comparison with the findings of angiography, digital subtracti...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:Endothelial cells synthesize and metabolize vasoactive substances which are involved in the regulation of vascular tone. Among these factors, the endothelium-derived nitric oxide (NO) appears to be of major importance. Many studies observed an impairment of the generation, release, or the diffusion of endothelial NO a...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：:This review summarizes some information on the management of diabetic patients at risk for or with already established coronary artery disease. Improved knowledge among diabetologists regarding treatment and prevention of cardiovascular complications and among cardiologists regarding diabetology is a prerequisite for ...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-008-3105-5
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study was the analysis of long-term results in patients with hemodynamically significant mitral valve disease due to extensively calcified mitral annulus who underwent decalcification and patch reconstruction. PATIENTS AND METHODS:Between 1996 and 2008 a total of 109 patients underwent surger...
journal_title：Herz
pub_type： 临床试验,杂志文章
doi：10.1007/s00059-011-3576-7
更新日期：2012-11-01 00:00:00
abstract：:Henoch-Schönlein purpura (HSP) is characterized by vasculitic involvement of small-sized vessels and results in multisystem manifestations. Cardiac involvement is extremely rare and myocardial infarction with coronary thrombus formation in those patients has also rarely been reported. Herein, we report a 33-year-old m...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-012-3597-x
更新日期：2012-11-01 00:00:00
abstract：:47 patients with aortic valve disease were studied by left ventricular micromanometry and cineangiography before and 18 months after successful valve replacement. There were 27 patients (17 with aortic stenosis, ten with aortic insufficiency) with moderate hypertrophy (angiographic mass less than 180 g/m2) and 20 pati...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
