[Wine consumption and prevention of coronary artery disease].

Abstract:

:There is a J-shaped correlation between the amount of alcohol consumed per day and overall mortality risk and an inverse correlation between the amount of alcohol consumed per day and cardiovascular mortality. The evidence is stronger for men than for women. The correlations are independent of the type of alcoholic beverage predominantly consumed. Possible mechanisms explaining the cardioprotective, antiatherosclerotic effects of moderate alcohol consumption are inhibition of platelet aggregation, increase in serum high density lipoprotein (HDL) levels and prevention of diabetes mellitus. The two latter mechanisms can also explain a delayed progression of atherosclerosis due to alcohol consumption. The beneficial effects are counteracted by detrimental effects of alcohol on the incidence of cancer diseases, liver cirrhosis, violence and accidents; therefore, alcohol consumption in general cannot be recommended for prevention of cardiovascular diseases.

journal_name

Herz

journal_title

Herz

authors

Flesch M,Morbach S,Erdmann E,Bulut D

doi

10.1007/s00059-016-4467-8

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

469-77

issue

6

eissn

0340-9937

issn

1615-6692

pii

10.1007/s00059-016-4467-8

journal_volume

41

pub_type

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