Abstract:
:There is a J-shaped correlation between the amount of alcohol consumed per day and overall mortality risk and an inverse correlation between the amount of alcohol consumed per day and cardiovascular mortality. The evidence is stronger for men than for women. The correlations are independent of the type of alcoholic beverage predominantly consumed. Possible mechanisms explaining the cardioprotective, antiatherosclerotic effects of moderate alcohol consumption are inhibition of platelet aggregation, increase in serum high density lipoprotein (HDL) levels and prevention of diabetes mellitus. The two latter mechanisms can also explain a delayed progression of atherosclerosis due to alcohol consumption. The beneficial effects are counteracted by detrimental effects of alcohol on the incidence of cancer diseases, liver cirrhosis, violence and accidents; therefore, alcohol consumption in general cannot be recommended for prevention of cardiovascular diseases.
journal_name
Herzjournal_title
Herzauthors
Flesch M,Morbach S,Erdmann E,Bulut Ddoi
10.1007/s00059-016-4467-8subject
Has Abstractpub_date
2016-09-01 00:00:00pages
469-77issue
6eissn
0340-9937issn
1615-6692pii
10.1007/s00059-016-4467-8journal_volume
41pub_type
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