Cardiac rhabdomyomas associated with tuberous sclerosis complex in children. From presentation to outcome.

abstract：:Based on the epidemiologic data of the Framingham heart study, arterial hypertension and coronary artery disease are the most frequent etiologic factors for the development of heart failure. In the pressure overloaded heart, hypertrophic growth of the myocardium includes the enlargement of cardiac myocytes stimulated ...

journal_title：Herz

authors： Funck RC,Wilke A,Rupp H,Maisch B,Brilla CG

更新日期：1995-10-01 00:00:00

abstract：:Diastolic heart failure, also known as heart failure with preserved left ventricular ejection fraction (HF-pEF), is responsible for approximately 50 % of all heart failure cases. According to current guidelines the diagnosis HF-pEF requires three criteria: (1) signs or symptoms of heart failure, (2) presence of a norm...

journal_title：Herz

authors： Weidemann F,Niemann M,Herrmann S,Ertl G,Störk S

更新日期：2013-02-01 00:00:00

abstract：:Regardless the general acceptance of cardiac operations by physicians and patients as routine procedures since the early seventies conventional cardiac surgery is still associated with a significant surgical trauma and exceptional invasiveness in part effected by the extracorporeal circulation. In parallel to the comm...

journal_title：Herz

authors： Cremer J,Böning A,Fraund S

更新日期：2002-08-01 00:00:00

abstract：:The presence of intraventricular obstruction is a powerful predictor of outcome in patients with hypertrophic cardiomyopathy (HCM) and, when associated with severe, drug-refractory symptoms, should be managed aggressively. Resting left ventricular outflow obstruction is found in approximately 20% of the patients, clas...

journal_title：Herz

authors： Cecchi F,Olivotto I,Nistri S,Antoniucci D,Yacoub MH

更新日期：2006-12-01 00:00:00

abstract：:To provide an overview of our experience with percutaneous balloon valvuloplasty in aortic stenosis, the results obtained in 218 patients have been analyzed. During the two years of its use, the technique of the procedure has been subsequently modified with increasing balloon diameters, initially 15 mm, 18 mm and then...

journal_title：Herz

authors： Cribier A,Letac B

更新日期：1988-04-01 00:00:00

abstract：:The use of drug-eluting stents (DESs) for patients with coronary artery disease is widespread. DESs have been associated with a lower rate of repeat revascularization, death, and myocardial infarction compared with bare metal stents. However, DESs can lead to a prothrombotic environment in the coronary arteries, resul...

journal_title：Herz

authors： Liu C,Liu M,Chen D,Liu H,Jiang Q,Lu J,Zuo L

更新日期：2015-08-01 00:00:00

abstract：:The risk of malignant arrhythmias is higher during extremely intense exercise and after its cessation. It is still unclear whether high-intensity interval exercise (HIE), an increasingly popular option in preventive and rehabilitative medicine, can lead to an impaired electrophysiological milieu, as revealed by QT int...

journal_title：Herz

authors： Nie J,Shi Q,Kong Z,Lao CK,Zhang H,Tong TK

更新日期：2020-12-01 00:00:00

abstract：:Although rarely reported, acute instent thrombosis can be life threatening, especially in cases where there are no ST segment changes. For this reason, careful history taking, follow-up, and prompt coronary angiography may be lifesaving. Herein, a case of acute stent thrombosis with no ST segment changes on electrocar...

journal_title：Herz

authors： Canpolat U,Sunman H,Yorgun H,Atalar E

更新日期：2012-05-01 00:00:00

abstract：:With increasing age valvular heart disease is among the most frequent diseases of the heart. Relevant valvular disease impairs not only the long-term prognosis but also physical resilience, activities of daily living and the quality of life. In cases of middle to high-grade symptomatic cardiac defects, valve replaceme...

journal_title：Herz

authors： Nechwatal RM,Bestehorn K,Leuschner F,Hagendorff A,Guha M,Schlitt A

更新日期：2020-04-20 00:00:00

abstract：:Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia with a prevalence of 0.5-10%, depending predominantly on age. The arrhythmia is associated with significant morbidity and mortality, mainly due to thromboembolic events including stroke and systemic embolisms. These complications can be e...

journal_title：Herz

authors： Erath JW,Hohnloser SH

更新日期：2018-02-01 00:00:00

abstract：:Exertional dyspnea is a nonspecific symptom with a variety of underlying causes. It can be challenging to differentiate a beginning cardiac disease from a pulmonary disease or from deconditioning alone. In the presence of obesity, the overall assessment is even more difficult. Rare diseases, such as pulmonary hyperten...

journal_title：Herz

authors： Wilkens H,Held M

更新日期：2018-09-01 00:00:00

abstract：:During the last decade, epigenetics became one of the fastest growing research fields in numerous clinical and basic science disciplines. Evidence suggests that chromatin modifications (e.g., histone modifications and DNA methylation) as well as the expression of micro-RNA molecules play a crucial role in the pathogen...

journal_title：Herz

authors： Zimmer P,Bloch W

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...

journal_title：Herz

authors： Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：:Our own previous studies of the composition of the extracellular matrix of human failing hearts showed that collagen VI seems to play a major role in the origin of cardiac fibrosis. Therefore, collagen VI was investigated in more detail in tissue samples taken from clinically normal left ventricle and from myocardium ...

journal_title：Herz

authors： Mollnau H,Münkel B,Schaper J

更新日期：1995-04-01 00:00:00

abstract：:The 4th edition of the Universal Definition of Myocardial Infarction (MI) recommends measurement of cardiac troponin (cTn) T or I for the diagnosis of MI due to their absolute cardiac tissue specificity. In this MI definition, values exceeding the 99th percentile of a healthy reference population distinguish between d...

journal_title：Herz

authors： Giannitsis E,Gopi V

更新日期：2020-09-01 00:00:00

abstract：:To assess the results of transluminal coronary angioplasty (TCA), 42 patients (mean age 50 years) with for coronary artery disease were investigated at rest and during exercise with the ECG (n = 40), thallium-201 myocardial scintigraphy (n = 23) and equilibrium-radionuclide ventriculography (n = 32). Each method of st...

journal_title：Herz

authors： Klepzig H Jr,Scherer D,Kober G,Maul FD,Kanemoto N,Standke R,Hör G,Kaltenbach M

更新日期：1981-08-01 00:00:00

abstract：:Direct inhibition of thrombin is a promising new strategy for the treatment of cardiovascular disease and thrombosis. Three intravenous (lepirudin, bivalirudin and argatroban) and one oral direct thrombin inhibitor (ximelagatran) are currently available and approved for some clinical indications in the treatment of ca...

journal_title：Herz

authors： Ahrens I,Bode C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:It is believed that most myocardial infarctions result from the rupture of "vulnerable plaques", that share certain common characteristics. These plaques typically consist of a lipid-rich core in the central portion of the thickened intima, covered by a thin friable fibrous cap. Today, one of the important c...

journal_title：Herz

authors： Gerckens U,Buellesfeld L,McNamara E,Grube E

更新日期：2003-09-01 00:00:00

abstract：:In 190 patients, 208 "screw-in" type pacemaker leads were implanted; 147 in the right ventricle and 61 in the right atrium. There was no significant difference in the time required for atrial (54.7 +/- 19 min) or ventricular fixation (56.0 +/- 25 min). Similarly, fluoroscopy times for both atrial (6.3 +/- 4 min) and v...

journal_title：Herz

authors： Machraoui A,Schött D,Ong TS,Straub H,Jaedicke W,Barmeyer J

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:The current study aimed to evaluate the influence of regular annual influenza vaccinations on cardiovascular (CV) death and heart failure-related hospitalizations (HFrH) in stable outpatients with heart failure with reduced ejection fraction. METHODS:The Turkish research team-HF (TREAT-HF) is a network unde...

journal_title：Herz

authors： Kaya H,Beton O,Acar G,Temizhan A,Cavusoğlu Y,Guray U,Zoghi M,Ural D,Ekmekci A,Gungor H,Sari I,Oguz D,Yucel H,Zorlu A,Yilmaz MB,TREAT-HF Investigators.

更新日期：2017-05-01 00:00:00

abstract：:After an unusually long period of time of 6 years, in August 2019 the updated version of the European Society of Cardiology (ESC) guidelines from 2013 on the management of stable coronary artery disease was published. The course of "stable" coronary artery disease is only assumed to be stable and pathologically is oft...

journal_title：Herz

authors： Silber S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:There is an increasing prevalence of older adults (> 65 years) with hypertension and the need for antihypertensive medication. It is well established that elderly hypertensive patients benefit from drug treatment with regards to cardiovascular morbidity and mortality. Due to the comorbidity and reduced quali...

journal_title：Herz

authors： Michalsen A,Wenzel RR,Mayer C,Broer M,Philipp T,Dobos GJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...

journal_title：Herz

authors： Brilla CG,Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：:Marfan syndrome is a hereditary disease with a prevalence of 2-3 in 10,000 births, leading to a fibrillin connective tissue disorder with manifestations in the skeleton, eye, skin, dura mater and in particular the cardiovascular system. Since other syndromes demonstrate similar vascular manifestations, but therapy may...

journal_title：Herz

authors： Kallenbach K,Schwill S,Karck M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Culture-negative endocarditis is a diagnostic challenge with variable clinical presentation and protean manifestations. ETIOLOGY AND DIAGNOSIS:The two main causes why endocarditis may be culture-negative are 1. antibiotic treatment prior to obtaining blood cultures, and 2. the presence of fastidious microor...

journal_title：Herz

authors： Kupferwasser LI,Bayer AS

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Inherited ventricular arrhythmias such as the long QT syndrome (LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), idiopathic ventricular fibrillation (VF), and arrhythmogenic right ventricular cardiomyopathy (ARVC) account for a relevant proportion of sudden cardiac death...

journal_title：Herz

authors： Wichter T,Schulze-Bahr E,Eckardt L,Paul M,Levkau B,Meyborg M,Schäfers M,Haverkamp W,Breithardt G

更新日期：2002-12-01 00:00:00

abstract：:Via the internet smartphones allow the download of applications ("Apps") that can address various requirements of daily life. These technical advances create new opportunities to better meet needs of patients suffering from hypertension. This may apply particularly for medication adherence, blood pressure control and ...

journal_title：Herz

authors： Becker S,Mitchell A,Königsmann T,Kribben A,Erbel R

更新日期：2012-11-01 00:00:00

abstract：:Over the past decade there has been a steady proliferation of indices which have been proposed for assessing ventricular function. Many of these indices are based on single measurements and often are insensitive and have limited clinical utility. The present article focuses on the role of wall stress in assessing vent...

journal_title：Herz

authors： Mirsky I,Krayenbuehl HP

更新日期：1981-10-01 00:00:00

abstract：:During the last decade, we have witnessed substantial improvements in the therapeutic options for pulmonary arterial hypertension (PAH), including true innovations targeting some of the mechanisms involved in the pathogenesis of this devastating disease. Intravenous epoprostenol was the first drug to improve symptoms ...

journal_title：Herz

authors： Hoeper MM

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Modern high-resolution imaging techniques have provided new insights into the pathogenesis of aortic dissection during recent years. Distinct pathologic entities or potential precursors of classic false-lumen aortic dissection such as intramural hematoma or penetrating atherosclerotic ulcer have been identif...

journal_title：Herz

authors： Eggebrecht H,Baumgart D,Herold U,Piotrowski J,Barkhausen J,Wiesemes R,Peters J,Rühm SG,Jakob H,Erbel R

更新日期：2002-09-01 00:00:00