Abstract：
BACKGROUND:Modern high-resolution imaging techniques have provided new insights into the pathogenesis of aortic dissection during recent years. Distinct pathologic entities or potential precursors of classic false-lumen aortic dissection such as intramural hematoma or penetrating atherosclerotic ulcer have been identified. As a result, a novel classification according to Svensson used in addition to the standard differentiation according to DeBakey or Stanford has been introduced. Due to improved diagnostic imaging, preoperative mortality has decreased but mortality remains substantial (up to 1.4% per hour within the first 2 days) related to complications of aortic dissection such as aortic rupture, bleeding, pericardial tamponade, critical branch vessel ischemia, multiorgan failure, and myocardial infarction. EXAMINATIONS:Transesophageal echocardiography, angiography, magnetic resonance imaging or computed tomography as well as intravascular ultrasound are used for a complete vascular "staging" of patients with aortic dissection after initial stabilization (with or without surgery). New catheter-based interventional techniques have been developed to improve the poor prognosis of aortic dissection: 1 Percutaneous balloon fenestration (PTF) of the intimal flap improves perfusion in case of bowel, limb, or renal ischemia. 2. Aortic stent-graft placement allows for occlusion of the intimal entry tear by implantation of a membrane-covered, self-expanding stent-graft to initiate progressive thrombus formation within the false lumen. Compared to the traditional surgical approaches, both techniques have a low complication rate. The development of these techniques may help to further improve to decrease patients' morbidity and mortality.
journal_name
Herzjournal_title
Herzauthors
Eggebrecht H,Baumgart D,Herold U,Piotrowski J,Barkhausen J,Wiesemes R,Peters J,Rühm SG,Jakob H,Erbel Rdoi
10.1007/s00059-002-2406-3keywords:
subject
Has Abstractpub_date
2002-09-01 00:00:00pages
539-47issue
6eissn
0340-9937issn
1615-6692journal_volume
27pub_type
杂志文章,评审相关文献
HERZ文献大全abstract：:While there is generell agreement that patients with aortic stenosis (AS) who have already developed symptoms, such as exertional dyspnea, angina or dizziness and syncope, require urgent surgery because of their otherwise very poor outcome, the management of asymptomatic severe AS remains controversial. Although preve...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-006-2871-1
更新日期：2006-10-01 00:00:00
abstract：:At present, in patients with diabetes mellitus and coronary multivessel disease no fixed general recommendation can be given in favor or to the disadvantage of surgical revascularization or in favor or to the disadvantage of percutaneous coronary intervention (PCI). In cases with an evidence-based indication for coron...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-010-3342-2
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation (AF) recurrence after ablation is difficult to predict. The development of AF is associated with inflammation, and inflammatory markers such as big endothelin-1 (big ET-1) reflect inflammatory status. It is unknown, however, whether big ET-1 can be used as a predictor for AF recurrence. T...
journal_title：Herz
pub_type： 临床试验,杂志文章
doi：10.1007/s00059-012-3626-9
更新日期：2012-12-01 00:00:00
abstract：:Independent of the underlying cause, pulmonary hypertension (PH) remains a devastating condition that is characterized by limited survival. Cumulating evidence indicates that in addition to a dysbalance of mediators regulating vascular tone and growth factors promoting vascular remodeling, failure to resolve inflammat...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-019-4795-6
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Inducible nitric oxide synthase (iNOS) single-nucleotide polymorphisms have been reported to confer susceptibility to hypertension, but no consensus has been reached. The aim of this study was to investigate the association between iNOS and hypertension in a Chinese population. METHODS:This was a case-contr...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-017-4591-0
更新日期：2018-08-01 00:00:00
abstract：:The incidence of coronary heart disease and myocardial infarction fell gradually during the seventies. Reasons for this decline are not well understood. Speculations include changes of life style and health care. However, cardiovascular disease is still the leader of mortality in Western developed countries. Mortality...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:Unstable angina accounts for more than one million hospital admissions annually. 6-8% of patients with this condition have non-fatal myocardial infarction or die within the first year after diagnosis. Recently, the term "acute coronary syndromes" has been used to describe the spectrum of conditions that incl...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/pl00002018
更新日期：2001-03-01 00:00:00
abstract：:We present a case of severe congestive left heart failure due to profound and long-term hypocalcemia caused by surgically induced hypoparathyroidism. Hypocalcemia as a potential contributor to heart failure should be included in the differential diagnosis of all patients with congestive heart failure who do not respon...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-010-3374-7
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-003-2524-6
更新日期：2003-12-01 00:00:00
abstract：:Chronic heart failure has an age-dependent prevalence of 2% and is therefore one of the most frequent diseases in western societies. A reduced hemoglobin concentration according to the definition of the World Health Organization is a common comorbidity affecting more than half of all heart failure patients. Elderly pa...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-3901-4
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Serum cholesterol is positively associated with the risk of developing coronary heart disease. The aim of this study was to determine the relation between response of coronary arteries to ergonovine provocation and lipid profile in patients with nonsignificant coronary artery disease. PATIENTS A...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-007-2831-4
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the prognostic value of restrictive right ventricular filling pattern (RRVFP) in patients with the first acute inferior wall myocardial infarction (IWMI) complicated by right ventricular myocardial infarction (RVMI) undergoing primary percutaneous coronary interventio...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-017-4631-9
更新日期：2019-04-01 00:00:00
abstract：:Acute heart failure is a symptom complex of heterogeneous etiology. Clinically, it comprises a broad spectrum ranging from hypertensive pulmonary edema in patients with preserved left ventricular systolic function up to cardiogenic shock in patients with severely depressed left ventricular function. The pathophysiolog...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-015-4336-x
更新日期：2015-08-01 00:00:00
abstract：:Studies of the efficacy of molsidomine, previously performed on our service, demonstrated that a clear antianginal effect in the longterm treatment of angina pectoris could only be achieved with a regimen of the standard 2 mg dose when given six times daily. Consequently, since a mode of administration with a longer d...
journal_title：Herz
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1984-12-01 00:00:00
abstract：OBJECTIVE:Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS:We performed CMR in 30 myocardial infarction (M...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-018-4741-z
更新日期：2019-12-01 00:00:00
abstract：:Blood pressure, the central parameter in the diagnosis of arterial hypertension, is subject to a high degree of variability. The dilemma for the evaluating physician is that he has no true value for the resting blood pressure that is both comparable and reproducible. Reproducibility, however, is an essential requireme...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:There is a J-shaped correlation between the amount of alcohol consumed per day and overall mortality risk and an inverse correlation between the amount of alcohol consumed per day and cardiovascular mortality. The evidence is stronger for men than for women. The correlations are independent of the type of alcoholic be...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-016-4467-8
更新日期：2016-09-01 00:00:00
abstract：:The term "chest pain with normal coronary arteries" encompasses a large number of different cardiac pathophysiological abnormalities, including impairment of coronary flow reserve, endothelial dysfunction, and early atherosclerosis that, in most cases, cannot be readily differentiated one from the other. To study earl...
journal_title：Herz
pub_type： 杂志文章,评审
doi：10.1007/s00059-005-2659-8
更新日期：2005-02-01 00:00:00
abstract：:Our own previous studies of the composition of the extracellular matrix of human failing hearts showed that collagen VI seems to play a major role in the origin of cardiac fibrosis. Therefore, collagen VI was investigated in more detail in tissue samples taken from clinically normal left ventricle and from myocardium ...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：BACKGROUND:In the present study, the electropharmacological activity of traditional Chinese medicine, Ginkgo biloba extract (GBE), on human hyperpolarization-activated nucleotide-gated (HCN) channels and the underlying "funny" currents was investigated. METHODS:Standard two-electrode voltage-clamp recordings were empl...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-020-04933-z
更新日期：2020-05-20 00:00:00
abstract：:In a prospective double-blind study of 40 male patients requiring aorto-coronary bypass surgery, a dose of 8 ng/kg/min of PGI2 was infused throughout extracorporeal circulation (ECC) (control group: glycine buffer). Between the two treatment groups there was no difference in preoperative hemodynamic parameters, number...
journal_title：Herz
pub_type： 临床试验,杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：BACKGROUND:The expansion of the transcatheter aortic valve replacement (TAVR) indication towards patients with intermediate surgical risk (Ref. Society of Thoracic Surgeons, STS, score) was analyzed. The aim was to investigate if the complication rates particularly with respect to TAVR and surgical aortic valve replace...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-018-4680-8
更新日期：2019-09-01 00:00:00
abstract：:Atrial fibrillation is by far the most common cardiac arrhythmia in humans. The incidence of atrial fibrillation increases with age and will increase even more in the future due to the demographic changes in the population. Therefore, this arrhythmia will have a growing clinical and socioeconomic impact. Although ther...
journal_title：Herz
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00059-017-4565-2
更新日期：2017-06-01 00:00:00
abstract：:Cardiac surgery in patients with chronic pulmonary diseases carries a high risk of postoperative pulmonary complications (ppc) because both are known to cause ppc. Autopsy studies have revealed ppc as the main cause of mortality in approximately 5-8% of patients after cardiac surgery. Not all pulmonary diseases are hi...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-4034-5
更新日期：2014-02-01 00:00:00
abstract：:In eleven patients with aortic dissection or perforated endocarditic aortic wall abscess cavity, the diagnostic usefulness of Color Doppler Echocardiography (CDE) for the identification of true and false lumen as well as the perforation jet was assessed by comparison with the findings of angiography, digital subtracti...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:With intravenous thrombolysis mortality of acute myocardial infarction can be significantly reduced, not only in the first hours after the onset of symptoms, but also up to 24 hours. The open infarct related coronary artery is important concerning long-term clinical outcome. If thrombolysis can be administered within ...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1992-02-01 00:00:00
abstract：:47 patients with aortic valve disease were studied by left ventricular micromanometry and cineangiography before and 18 months after successful valve replacement. There were 27 patients (17 with aortic stenosis, ten with aortic insufficiency) with moderate hypertrophy (angiographic mass less than 180 g/m2) and 20 pati...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:In patients with chronic coronary artery disease different therapeutic strategies, such as optimal medical therapy, revascularization by percutaneous coronary intervention or coronary artery bypass grafting have been shown to improve the prognosis and symptoms and yield proven superiority over other treatment strategi...
journal_title：Herz
pub_type： 杂志文章
doi：10.1007/s00059-013-3803-5
更新日期：2013-06-01 00:00:00
abstract：:M-mode, two-dimensional and Doppler echocardiography enable evaluation of morphologic changes in valvular structures, detection of secondary changes in cardiac chambers and left ventricular function and quantification of blood flow patterns. In mitral stenosis, with M-mode echocardiography the diagnosis can be establi...
journal_title：Herz
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
abstract：:Nitrates have been periodically controversial since their introduction in 1867 as a treatment for angina pectoris. The goal of this synopsis is to delineate the special and unchanged high ranking of nitrates in the treatment of angina pectoris with particular consideration to the dosage and dosage intervals. The anti-...
journal_title：Herz
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
