Androgen deficiency in the aging male: when to evaluate and when to treat.

Abstract:

:Aging can be associated with an abnormal decline in testosterone production, mainly due to pituitary failure, and is reflected by low serum testosterone concentrations. Manifestations of testosterone deficiency can be subtle, can be misinterpreted as consequences of normal aging, and include lack of libido and energy, mood changes, impaired strength, and development of osteoporosis. The most important factor in the evaluation and treatment of this age-related, usually unrecognized abnormality is the public awareness of its frequent occurrence that will stimulate the use of appropriate screening tests, beginning with a morning testosterone level. Replacement therapy by parenteral or transdermal testosterone administration can be highly beneficial in alleviating the manifestations of hypogonadism and improving quality of life. Careful screening and meticulous follow-up are mandatory. The long-term effects of testosterone replacement on the cardiovascular system, the prostate, and on longevity are unknown.

journal_name

Curr Urol Rep

journal_title

Current urology reports

authors

Nolten WE

doi

10.1007/s11934-000-0013-5

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

313-9

issue

4

eissn

1527-2737

issn

1534-6285

journal_volume

1

pub_type

杂志文章,评审
  • Lymphotropic nanoparticle-enhanced MRI in prostate cancer: value and therapeutic potential.

    abstract::Nodal staging in prostate cancer is suboptimal both with respect to current imaging modalities and pelvic lymph node dissection, and thus other techniques are being explored. Lymphotropic nanoparticle-enhanced MRI, also called magnetic resonance lymphography (MRL), is a technique that has shown high sensitivity (65-92...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-013-0389-7

    authors: Fortuin AS,Smeenk RJ,Meijer HJ,Witjes AJ,Barentsz JO

    更新日期:2014-03-01 00:00:00

  • Salvage Therapy Options for Local Prostate Cancer Recurrence After Primary Radiotherapy: a Literature Review.

    abstract:PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-017-0709-4

    authors: Golbari NM,Katz AE

    更新日期:2017-08-01 00:00:00

  • Application of TAP Block in Laparoscopic Urological Surgery: Current Status and Future Directions.

    abstract:PURPOSE OF REVIEW:Amid the opioid crisis, postoperative pain management is a major challenge for practitioners. Recent pain management guidelines emphasize the importance of using regional anesthesia as part of opioid-sparing multimodal analgesia. This report aims to review recent evidence regarding the utilization of ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-019-0883-7

    authors: Shahait M,Lee DI

    更新日期:2019-03-23 00:00:00

  • Cerebral control of bladder function.

    abstract::Symptoms such as overactive bladder represent disorders of bladder control. Functional brain scanning by positron emission tomography and functional magnetic resonance imaging suggest that normal control is exerted by a network of regions in the emotional nervous system, including periaqueductal gray, thalamus, insula...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-004-0081-z

    authors: Griffiths DJ

    更新日期:2004-10-01 00:00:00

  • Genomic Subtyping in Bladder Cancer.

    abstract:PURPOSE OF REVIEW:Molecular characterization of cancer allows us to understand oncogenesis and clinical prognosis as well as facilitates development of biomarkers and treatment. Our aim was to review the current literature on genomic characterization of bladder cancer, and how far we are in implementing genomics into c...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-020-0960-y

    authors: Jalanko T,de Jong JJ,Gibb EA,Seiler R,Black PC

    更新日期:2020-03-13 00:00:00

  • Conservative management options for Peyronie's disease.

    abstract::Peyronie's disease is an acquired condition that presents clinically with a palpable induration, a distinct plaque, or a curvature of the erect penis. At times, the erections are painful. Erectile dysfunction (ED) often is associated with Peyronie's disease. The current era of phosphodiesterase therapy for the treatme...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-005-0041-2

    authors: Jack GS,Gonzalez-Cadavid N,Rajfer J

    更新日期:2005-11-01 00:00:00

  • Lymph node staging in prostate cancer.

    abstract::Nodal staging is important in prostate cancer treatment. While surgical lymph node dissection is the classic method of determining whether lymph nodes harbor malignancy, this is a very invasive technique. Current noninvasive approaches to identifying malignant lymph nodes are limited. Conventional imaging methods rely...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-015-0505-y

    authors: Sankineni S,Brown AM,Fascelli M,Law YM,Pinto PA,Choyke PL,Turkbey B

    更新日期:2015-05-01 00:00:00

  • Validity of Claims Data for the Identification of Male Infertility.

    abstract:PURPOSE OF REVIEW:We sought to determine whether infertile men can accurately be identified within a large insurance claims database to validate its use for reproductive health research. RECENT FINDINGS:Prior literature suggests that men coded for infertility are at higher risk for chronic disease though it was previo...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-017-0714-7

    authors: Khandwala YS,Zhang CA,Li S,Cullen MR,Eisenberg ML

    更新日期:2017-09-01 00:00:00

  • The Emergence of Kidney Stone Disease During Childhood-Impact on Adults.

    abstract:PURPOSE OF REVIEW:The goal of this chapter is to review the recent epidemiologic trends of kidney stone disease and discuss the impact of the increasing incidence of nephrolithiasis among children on adults with respect to extra-renal manifestations, surgical management, and secondary prevention. RECENT FINDINGS:Among...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-017-0691-x

    authors: Bonzo JR,Tasian GE

    更新日期:2017-06-01 00:00:00

  • Transvaginal bladder neck suspension to Cooper's ligament.

    abstract::Numerous surgeries have been proposed for the treatment of genuine stress incontinence, with the goals to improve functional outcome and decrease complications and their associated morbidity. Two new, minimally invasive procedures, transvaginal retropubic urethropexy and transvaginal Cooper's ligament sling, are revie...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-996-0018-9

    authors: Koduri S,Sand P

    更新日期:2001-10-01 00:00:00

  • Justification of extraperitoneal laparoscopic access for surgery of the upper urinary tract.

    abstract::Laparoscopic surgery was originally developed by gynecologists and general surgeons. Based on their experience, the first successful laparoscopic procedures in urology were performed transperitoneally. However, this novel technique transformed traditionally retroperitoneal procedures into transperitoneal procedures, g...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-004-0020-z

    authors: Hoznek A,Salomon L,Gettman M,Stolzenburg JU,Abbou CC

    更新日期:2004-04-01 00:00:00

  • Prostate Cancer Imaging with Novel PET Tracers.

    abstract::Molecular imaging of prostate cancer is in a dynamic phase of development. Currently approved techniques are limited and researchers have been working on novel agents to improve accuracy in targeting and detecting prostate tumors. In addition, the complexity of various prostate cancer states also contributes to the ch...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-016-0575-5

    authors: Lindenberg L,Choyke P,Dahut W

    更新日期:2016-03-01 00:00:00

  • Production of urothelium from pluripotent stem cells for regenerative applications.

    abstract::As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are attractive cand...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-014-0466-6

    authors: Osborn SL,Kurzrock EA

    更新日期:2015-01-01 00:00:00

  • Overview of Dietary Supplements in Prostate Cancer.

    abstract::Prostate cancer is a key health concern for men with its etiology still under investigation. Recently, the role of dietary supplements has been noted to have a major inhibitory effect on prostate cancer and numerous studies have been conducted in this regard. This review provides a summary on numerous recent studies c...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-016-0637-8

    authors: Yacoubian A,Dargham RA,Khauli RB,Bachir BG

    更新日期:2016-11-01 00:00:00

  • Troubleshooting Complex Vascular Cases in the Kidney Graft: Multiple Vessels, Aneurysms, and Injuries During Harvesting Procedures.

    abstract:PURPOSE OF THE REVIEW:To update the most relevant literature regarding complex vascular cases in kidney transplant setting involving the graft, especially during the harvesting procedure and back-table preparation from the subsequent implant. RECENT FINDINGS:Challenging situations affecting the kidney graft such as mu...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-020-0955-8

    authors: Hevia V,Gómez V,Hevia M,Lorca J,Santiago M,López-Plaza J,Álvarez S,Díez V,Gordaliza C,Burgos FJ

    更新日期:2020-01-31 00:00:00

  • Repair of pelvic organ prolapse: what is the goal?

    abstract::The objective of this review is to discuss the main goals of pelvic organ prolapse repair. Pelvic organ prolapse symptoms are variable, and prolapse degree does not necessarily correlate with perceived symptoms or other associated conditions including urinary, defecatory, and sexual dysfunction. Treatment for pelvic o...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-013-0385-y

    authors: Aponte MM,Rosenblum N

    更新日期:2014-02-01 00:00:00

  • Bladder Preservation Therapy: Review of Literature and Future Directions of Trimodal Therapy.

    abstract:PURPOSE OF THE REVIEW:This review targets the latest literature on bladder preservation therapy with emphasis on trimodal therapy (TMT), highlighting its role in the management of muscle invasive bladder cancer (MIBC) and outlining future directions in bladder preservation research. RECENT FINDINGS:TMT is the most pro...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-018-0859-z

    authors: El-Achkar A,Souhami L,Kassouf W

    更新日期:2018-11-03 00:00:00

  • UTIs in patients with neurogenic bladder.

    abstract::Urinary tract infections (UTI) remain one of the most prevalent and frustrating morbidities for neurogenic bladder patients, and death attributed to urosepsis in the spinal cord injury (SCI) patient is higher when compared to the general population. Risk factors include urinary stasis, high bladder pressures, bladder ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-014-0433-2

    authors: Jahromi MS,Mure A,Gomez CS

    更新日期:2014-09-01 00:00:00

  • How to minimize lymphoceles and treat clinically symptomatic lymphoceles after radical prostatectomy.

    abstract::The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-014-0445-y

    authors: Lee HJ,Kane CJ

    更新日期:2014-10-01 00:00:00

  • Current approaches to the urologic care of children with spina bifida.

    abstract::Most children born with spina bifida, the most common disabling congenital abnormality, have normal renal function. If left untreated, more than half of these children will have serious renal deterioration by age 5. This deterioration is secondary to hostile neurogenic changes of the bladder. Renal development should ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-008-0027-y

    authors: Joseph DB

    更新日期:2008-03-01 00:00:00

  • The Role of Interventional Radiology Techniques in the Management of Renal Angiomyolipomas.

    abstract:PURPOSE OF REVIEW:Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS:For patients with renal mass...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-017-0687-6

    authors: Kiefer RM,Stavropoulos SW

    更新日期:2017-05-01 00:00:00

  • Prostate-specific antigen and prostate-specific antigen derivatives as predictors of benign prostatic hyperplasia progression.

    abstract::Benign prostatic hyperplasia (BPH) is the most common urologic affliction in aging men, leading to adverse clinical outcomes in a significant proportion of the population. Serum prostate-specific antigen (PSA) has been established as a marker for prostate cancer for the past two decades but more recently has been reco...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-007-0072-y

    authors: Levitt JM,Slawin KM

    更新日期:2007-07-01 00:00:00

  • Role and extent of lymphadenectomy during radical cystectomy for invasive bladder cancer.

    abstract::There is substantial variability in the extent of the node dissection performed during radical cystectomy for bladder cancer. Here, we review the diagnostic assessment of lymph node metastasis and the prognostic and therapeutic benefit for pelvic node dissection for bladder cancer. A review of the applicable urologic ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-012-0235-3

    authors: Svatek R,Zehnder P

    更新日期:2012-04-01 00:00:00

  • Patient-Reported Outcome Measures (PROMs) in Pelvic Floor Disorders.

    abstract:PURPOSE OF REVIEW:Patient-reported outcome measures (PROMs) are tools that are widely used by clinicians and researchers across different medical specialties. In this review, we examine the use of PROMs in the evaluation of female pelvic floor disorders (PFD). RECENT FINDINGS:PROM development in the assessment of urin...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-019-0888-2

    authors: Habashy E,Mahdy AE

    更新日期:2019-03-27 00:00:00

  • Nerve-sparing during robotic radical prostatectomy: use of computer modeling and anatomic data to establish critical steps and maneuvers.

    abstract::This paper is aimed at focusing on the nerve-sparing aspect of the robotic prostatectomy. It reviews the existing principles and presents the arguments based on robotic fresh cadaver dissections and from actual robotic prostatectomy cases. ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-005-0080-8

    authors: Tewari A,El-Hakim A,Horninger W,Peschel R,Coll D,Bartsch G

    更新日期:2005-03-01 00:00:00

  • An update on phthalates and male reproductive development and function.

    abstract::Phthalates are part of a class of high-volume industrial chemicals used ubiquitously in health care as well as household products. Biomarker studies have confirmed the widespread presence of these chemicals in both humans and animals. As a class, phthalates have been implicated in diseases and birth anomalies of the g...

    journal_title:Current urology reports

    pub_type: 杂志文章

    doi:10.1007/s11934-012-0261-1

    authors: Grady R,Sathyanarayana S

    更新日期:2012-08-01 00:00:00

  • Evaluating Urology Residency Applications: What Matters Most and What Comes Next?

    abstract:PURPOSE OF REVIEW:In light of the announcement that the United States Medical Licensing Examination Step 1 exam will transition to pass/fail reporting, we reviewed recent literature on evaluating residency applicants with a focus on identifying objective measurements of applicant potential. RECENT FINDINGS:References ...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-020-00993-0

    authors: Huang MM,Clifton MM

    更新日期:2020-08-17 00:00:00

  • Alternative therapies for the treatment of chronic prostatitis.

    abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent disease for which there is no standardized therapy. Traditional treatments have included antibiotics, α-blockers, and anti-inflammatories, but those have not proven to be efficacious therapies through many clinical trials. Alternative therapies,...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-011-0188-y

    authors: Suh LK,Lowe FC

    更新日期:2011-08-01 00:00:00

  • Robotic high-intensity focused ultrasound for prostate cancer: what have we learned in 15 years of clinical use?

    abstract::High-intensity focused ultrasound (HIFU) is an emerging, noninvasive, local treatment of prostate cancer with 15 years of clinical experience, during which about 30,000 HIFU treatments have been performed worldwide. In this paper, we review relevant publications regarding the means by which new and old prostate cancer...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-011-0184-2

    authors: Chaussy CG,Thüroff SF

    更新日期:2011-06-01 00:00:00

  • Cell type-specific analyses for identifying prostate cancer biomarkers.

    abstract::Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities dir...

    journal_title:Current urology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11934-006-0039-4

    authors: Nelson PS,Montgomery B

    更新日期:2006-01-01 00:00:00