Abstract:
:Humans take a long time to respond to the slow visual motion of an object. It is not known what neural mechanism causes this delay. We measured magnetoencephalographic neural responses to light spot motion onset within a wide speed range (0.4-500 degrees /sec) and compared these with human reaction times (RTs). The mean response latency was inversely related to the speed of motion up to 100 degrees /sec, whereas the amplitude increased with the speed. The response property at the speed of 500 degrees /sec was different from that at the other speeds. The speed-related latency change was observed when the motion duration was 10 msec or longer in the speed range between 5 and 500 degrees /sec, indicating that the response is directly related to the speed itself. The source of the response was estimated to be around the human MT+ and was validated by functional magnetic imaging study using the same stimuli. The results indicate that the speed of motion is encoded in the neural activity of MT+ and that it can be detected within 10 msec of motion observation. RT to the same motion onset was also inversely related to the speed of motion but the delay could not be explained by the magnetic response latency change. Instead, the reciprocal of RT was linearly related to the reciprocal of the magnetic response latency, suggesting that the visual process interacts with other neural processes for decision and motor preparation.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Kawakami O,Kaneoke Y,Maruyama K,Kakigi R,Okada T,Sadato N,Yonekura Ydoi
10.1002/hbm.10033keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
104-18issue
2eissn
1065-9471issn
1097-0193pii
10.1002/hbm.10033journal_volume
16pub_type
杂志文章abstract::There have been many functional imaging studies of the brain basis of theory of mind (ToM) skills, but the findings are heterogeneous and implicate anatomical regions as far apart as orbitofrontal cortex and the inferior parietal lobe. The functional imaging studies are reviewed to determine whether the diverse findin...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.20671
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Abnormalities in inhibitory control and underlying fronto-striatal networks is common to both attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive-disorder (OCD). The aim of this study was to investigate disorder-specific abnormalities in neural networks mediating interference inhibition ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21048
更新日期:2011-04-01 00:00:00
abstract::In this communication, we extended a previously described and validated diffusion tensor imaging (DTI) method for segmenting whole brain cerebrospinal fluid (CSF) and gray and white matter (WM) tissue to provide regional volume and DTI metrics of WM tract and cortical and subcortical gray matter. This DTI-based region...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21004
更新日期:2011-01-01 00:00:00
abstract::In the present study, functional magnetic resonance imaging (fMRI) was used to examine pain perception in humans. Three types of noxious stimuli were presented: electric shock (20.8 mA, 2 Hz), heat (48 degrees C), and mechanical, as well as a control tactile stimulus. The significance of activation at the level of the...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The question of how spatially organized activity in the visual cortex behaves during eyes-closed, lysergic acid diethylamide (LSD)-induced "psychedelic imagery" (e.g., visions of geometric patterns and more complex phenomena) has never been empirically addressed, although it has been proposed that under psychedelics, ...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.23224
更新日期:2016-08-01 00:00:00
abstract::The functional organization of the human brain consists of a high degree of connectivity between interhemispheric homologous regions. The degree of homotopic organization is known to vary across the cortex and homotopic connectivity is high in regions that share cross-hemisphere structural connections or are activated...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23214
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intravascular angioplasty and stenting of intracranial arterial stenosis provided controversial results. Besides the expertise of the practitioners, the selection of the patients remains challenging. BOLD MRI of the cerebral vasoreactivity (BOLD MRI CVR) to hypercapnia provides reproducible maps ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22255
更新日期:2014-04-01 00:00:00
abstract::Cortical surface templates are an important standardized coordinate frame for cortical structure and function analysis in magnetic resonance (MR) imaging studies. The widely used adult cortical surface templates (e.g., fsaverage, Conte69, and the HCP-MMP atlas) are based on the Caucasian population. Neuroanatomical di...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24960
更新日期:2020-06-15 00:00:00
abstract::The resting state default mode network (DMN) has been shown to characterize a number of neurological and psychiatric disorders. Evidence suggests an underlying genetic basis for this network and hence could serve as potential endophenotype for these disorders. Heritability is a defining criterion for endophenotypes. T...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22446
更新日期:2014-08-01 00:00:00
abstract::The central extended amygdala (EAc)-including the bed nucleus of the stria terminalis (BST) and central nucleus of the amygdala (Ce)-plays a critical role in triggering fear and anxiety and is implicated in the development of a range of debilitating neuropsychiatric disorders. Although it is widely believed that these...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23917
更新日期:2018-03-01 00:00:00
abstract::Migraine sufferers with aura often report photosensitivity and visual discomfort outside of attacks and many consider bright or flickering light an attack-precipitating factor. The nature of this visual hypersensitivity and its relation to the underlying pathophysiology of the migraine aura is unknown. Using fMRI meas...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22361
更新日期:2014-06-01 00:00:00
abstract::The sulcal morphology of the human frontal lobe is highly variable. Although the structural images usually acquired in functional magnetic resonance imaging studies provide information about this interindividual variability, this information is only rarely used to relate structure and function. Here, we investigated t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20501
更新日期:2009-01-01 00:00:00
abstract::Despite the clinical significance of event-related potential (ERP) latency abnormalities, little attention has focused on the anatomic substrate of latency variability. Volume conduction models do not identify the anatomy responsible for delayed neural transmission between neural sources. To explore the anatomic subst...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20103
更新日期:2005-07-01 00:00:00
abstract::No study has investigated red nucleus (RN) atrophy in multiple sclerosis (MS) despite cerebellum and its connections are elective sites of MS-related pathology. In this study, we explore RN atrophy in early MS phases and its association with cerebellar damage (focal lesions and atrophy) and physical disability. Thirty...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25213
更新日期:2021-01-01 00:00:00
abstract::The histaminergic involvement in selective processes underlying its role in human sensori-motor performance is largely unknown. Recently, selective effects of central H₁-inverse agonism on sensory visual processes were observed in electrophysiological--but not behavioral data; a discrepancy suggested to result from sp...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.22387
更新日期:2014-07-01 00:00:00
abstract::The effect of stimulus modulation rate on the underlying neural activity in human auditory cortex is not clear. Human studies (using both invasive and noninvasive techniques) have demonstrated that at the population level, auditory cortex follows stimulus envelope. Here we examined the effect of stimulus modulation ra...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21100
更新日期:2011-08-01 00:00:00
abstract::Task-switching performance relies on a broadly distributed frontoparietal network and declines in older adults. In this study, they investigated whether this age-related decline in task switching performance was mediated by variability in global or regional white matter microstructural health. Seventy cognitively inta...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23473
更新日期:2017-03-01 00:00:00
abstract::Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and th...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23976
更新日期:2018-05-01 00:00:00
abstract::Functional imaging studies consistently find that emotional stimuli activate the posterior cingulate cortex, a region that appears to have memory-related functions. However, prior imaging studies have not controlled for non-emotional stimulus features that might activate this region by engaging memory processes unrela...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10075
更新日期:2003-01-01 00:00:00
abstract::Electrophysiological and neuroimaging studies suggest that the integrity of ipsilesional and inter-hemispheric motor circuits is important for motor recovery after stroke. However, the extent to which each of these tracts contributes to the variance in outcome remains unclear. We examined whether diffusion tensor imag...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21266
更新日期:2012-05-01 00:00:00
abstract::Prenatal alcohol exposure (PAE) can cause central nervous system dysfunction and widespread structural anomalies as detected by magnetic resonance imaging (MRI). This study focused on diffusion tensor imaging (DTI) of white matter in a large sample of PAE participants that allowed us to examine correlations with behav...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23371
更新日期:2017-01-01 00:00:00
abstract::We propose a hardware and software architecture to respond to crucial problems in the neuroimaging field: storage, retrieval, and processing of large datasets. The B-SPID project, here discussed, concerns the processing of neuroimages and attached components stored in an object-relational multimedia database managemen...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)7:2<136::aid-hbm6>3.0
更新日期:1999-01-01 00:00:00
abstract::Our objective was to develop a diffusion tensor MR imaging pulse sequence that allows whole brain coverage with isotropic resolution within a clinically acceptable time. A single-shot, cardiac-gated MR pulse sequence, optimized for measuring the diffusion tensor in human brain, was developed to provide whole-brain cov...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10018
更新日期:2002-04-01 00:00:00
abstract::The present fMRI study used a spelling task to investigate the hypothesis that the left ventral occipitotemporal cortex (vOT) hosts neuronal representations of whole written words. Such an orthographic word lexicon is posited by cognitive dual-route theories of reading and spelling. In the scanner, participants perfor...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22709
更新日期:2015-04-01 00:00:00
abstract::Verbal stimuli often induce right-hemispheric activation in patients with aphasia after left-hemispheric stroke. This right-hemispheric activation is commonly attributed to functional reorganization within the language system. Yet previous evidence suggests that functional activation in right-hemispheric homologues of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21512
更新日期:2013-06-01 00:00:00
abstract::Huntington disease (HD) is a neurodegenerative disorder that involves preferential atrophy in the striatal complex and related subcortical nuclei. In this article, which is based on a dataset extracted from the PREDICT-HD study, we use statistical shape analysis with deformation markers obtained through "Large Deforma...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22214
更新日期:2014-03-01 00:00:00
abstract::Inattentional deafness is the failure to hear otherwise audible sounds (usually alarms) that may occur under high workload conditions. One potential cause for its occurrence could be an attentional bottleneck that occurs when task demands are high, resulting in lack of resources for processing of additional tasks. In ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23735
更新日期:2017-11-01 00:00:00
abstract::Functional and anatomical asymmetries are prevalent features of the human brain, linked to gender, handedness, and cognition. However, little is known about the neurodevelopmental processes involved. In zebrafish, asymmetries arise in the diencephalon before extending within the central nervous system. We aimed to ide...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22401
更新日期:2014-07-01 00:00:00
abstract::Depressive symptoms often coexist with memory deficits in older adults and also are associated with incident cognitive decline in the elderly. However, little is known about the neural correlates of the association between depressive symptoms and memory deficits in nondemented elderly. Fifteen amnestic mild cognitive ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21291
更新日期:2012-06-01 00:00:00
abstract::Most of the previous task functional magnetic resonance imaging (fMRI) studies found abnormalities in distributed brain regions in mild cognitive impairment (MCI) and Alzheimer's disease (AD), and few studies investigated the brain network dysfunction from the system level. In this meta-analysis, we aimed to examine b...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析,评审
doi:10.1002/hbm.22689
更新日期:2015-03-01 00:00:00