Compartments in the lamprey embryonic brain as revealed by regulatory gene expression and the distribution of reticulospinal neurons.

abstract：:A simple, inexpensive hardware and software protocol is described for conditioning and testing hearing of gerbils with minimal experimenter involvement. Behavioral thresholds correspond closely with data which employ nonautomated procedures. Partial source listings of the programs written in the 'C' programming langua...

journal_title：Brain research bulletin

authors： Gans G

更新日期：1989-02-01 00:00:00

abstract：:Reticulons (RTNs) are a group of membrane-bound proteins that are dominantly localized to the endoplasmic reticulum (ER). RTN1-C, one isoform of RTNs highly expressed in the brain, has been shown to mediate neuronal injury in cerebral ischemia models. The aim of this study was to investigate the role of RTN1-C in an i...

journal_title：Brain research bulletin

authors： Chang J,Zhang XL,Yu H,Chen J

更新日期：2019-03-01 00:00:00

abstract：:The nucleus locus coeruleus (LC) has been implicated in the modulation of the spinal sensorimotor function. The aim of the present study was to examine the effect of electrical stimulation of the LC on sensorimotor function in the trigeminal system. The following two cases of sensorimotor behaviors mediated by the tri...

journal_title：Brain research bulletin

authors： Matsutani K,Tsuruoka M,Shinya A,Furuya R,Kawawa T

更新日期：2000-12-01 00:00:00

abstract：:The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson's disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exact molecular mechani...

journal_title：Brain research bulletin

authors： Anandhan A,Jacome MS,Lei S,Hernandez-Franco P,Pappa A,Panayiotidis MI,Powers R,Franco R

更新日期：2017-07-01 00:00:00

abstract：:The ontogeny of sensorimotor behaviors of albino rats were evaluated from birth through adulthood (Experiment 1). Sensorimotor behaviors (e.g., visual and tactile orientation, forelimb and hindlimb hopping, righting reflexes) achieved mature (adultlike) characteristics at various ages during ontogeny and a rostral-cau...

journal_title：Brain research bulletin

authors： Almli CR,Fisher RS

更新日期：1977-11-01 00:00:00

abstract：:In female rats, stimulation of the uterine cervix during mating induces two daily surges of prolactin. Inhibition of hypothalamic dopamine release and stimulation of oxytocin neurons in the paraventricular nucleus (PVN) are required for prolactin secretion. We aim to better understand how stimulation of the uterine ce...

journal_title：Brain research bulletin

authors： Poletini MO,McKee DT,Szawka RE,Bertram R,Helena CV,Freeman ME

更新日期：2012-09-01 00:00:00

abstract：:Development and resolution of the lesion produced by occlusion of the middle cerebral artery (MCAO) was studied through quantitative planimetry and histologic/immunohistochemical techniques. MCAO, performed in spontaneously hypertensive rats (SHR), initially (1-3 days) produced large, consistent cerebral cortical infa...

journal_title：Brain research bulletin

authors： Clark RK,Lee EV,Fish CJ,White RF,Price WJ,Jonak ZL,Feuerstein GZ,Barone FC

更新日期：1993-01-01 00:00:00

abstract：:GABA(A) receptors are chloride channels in the brain activated by binding of gamma-aminobutyric acid (GABA). Several important classes of drugs, including alcohol and certain antiepileptic drugs, modulate the actions of GABA. We report the sequence and expression of alpha4 subunits of GABA(A) receptors in two inbred s...

journal_title：Brain research bulletin

authors： Cestari IN,Liu ZF,Mu W,Burt DR

更新日期：1998-12-01 00:00:00

abstract：:The effects of endogenous hyperprolactinaemia (HPRL), as induced by pituitary homografts under the kidney capsule, on core temperature (Tc) was investigated in rats before and after the application of restraint stress. HPRL was accompanied by a significant decrease in Tc of freely moving rats, as observed for four day...

journal_title：Brain research bulletin

authors： Drago F,Amir S

更新日期：1984-04-01 00:00:00

abstract：:Rodent models for the study of neurogenic bladder dysfunction after spinal cord injury (SCI) are difficult to standardize, particularly when evaluating the specific contribution of the SCI to end-organ function. The purpose of this study was to evaluate the degree of bladder dysfunction associated with a highly reprod...

journal_title：Brain research bulletin

authors： Munoz A

更新日期：2017-05-01 00:00:00

abstract：:Isoflurane (ISO) is an anesthesia and can result in neuron injury. A previous study has indicated that microRNA-302b-3p (miR-302b-3p) exerts a crucial function in modulating cerebral ischemia/reperfusion damage-induced neuronal injury. We sought to examine the role of miR-302b-3p in ISO-induced neuronal injury. In the...

journal_title：Brain research bulletin

authors： Li L,Lu S,Fan X

更新日期：2020-12-25 00:00:00

abstract：:The hypothalamic suprachiasmatic nucleus (SCN) and the thalamic intergeniculate leaflet (IGL) are considered to be the main centers of the mammalian circadian timing system. In primates, the IGL is included as part of the pregeniculate nucleus (PGN), a cell group located mediodorsally to the dorsal lateral geniculate ...

journal_title：Brain research bulletin

authors： Cavalcante JS,Britto LR,Toledo CA,Nascimento ES Jr,Lima RR,Pontes AL,Costa MS

更新日期：2008-07-01 00:00:00

abstract：:The vestibular nuclei and posterior cerebellum are the destination of vestibular primary afferents and the subject of this review. The vestibular nuclei include four major nuclei (medial, descending, superior and lateral). In addition, smaller vestibular nuclei include: Y-group, parasolitary nucleus, and nucleus inter...

journal_title：Brain research bulletin

authors： Barmack NH

更新日期：2003-06-15 00:00:00

abstract：:Evidence exists that nitric oxide (NO) may mediate both protective and pathological responses during brain hypoxia (HP). Reactive oxygen species have also been implicated in the pathophysiological response of the brain tissues to HP. Therefore, this study investigated whether a NO precursor, l-arginine (l-arg), a free...

journal_title：Brain research bulletin

authors： Abdel Baky NA,Zaidi ZF,Fatani AJ,Sayed-Ahmed MM,Yaqub H

更新日期：2010-08-30 00:00:00

abstract：:The Lurcher (Lc/+) mutant mouse is characterized by a considerable atrophy of the cerebellum due to a massive loss of cerebellar Purkinje and granule cells, as well as of neurons from the inferior olivary nucleus. In this study the effects of a therapeutic combination of amantadine, thiamine and L-tryptophan on the se...

journal_title：Brain research bulletin

authors： Le Marec N,Hébert C,Botez MI,Botez-Marquard T,Marchand L,Reader TA

更新日期：1999-01-15 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a common neurological disease, causing severe disability and even deaths. Stem cell transplantation has been increasingly used in stroke therapy, and neural stem cells (NSCs) are a good source for stem cell transplantation. However, the regulatory mechanism of NSCs remains unclear. In...

journal_title：Brain research bulletin

authors： Sun Z,Wu K,Gu L,Huang L,Zhuge Q,Yang S,Wang Z

更新日期：2020-11-01 00:00:00

abstract：:Adult female Zucker lean and obese rats were treated for 14 days with 3.5 nm/kg oleoyl-estrone (OE) in liposomes (Merlin-2) through continuous i.v. injection with osmotic minipumps. Rat wt. and food intake were measured daily. On days 0, 3, 6, 10, and 14, groups of rats were killed and their hypothalamic nuclei [later...

journal_title：Brain research bulletin

authors： Cabot C,del Mar Grasa M,Estruch J,Fernández-López JA,Remesar X,Alemany M

更新日期：1998-08-01 00:00:00

abstract：:The conditions under which amyloid is toxic to primary rat hippocampal neurons were investigated. Synthetic A beta (1-42) peptide elicited neurotoxic activity following "aging" for 7 to 14 days at 37 degrees C in Modified Eagles Media. Neurotoxicity included decreases in neurite length, cell number, and a loss in 3-[4...

journal_title：Brain research bulletin

authors： Manelli AM,Puttfarcken PS

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is a gaseous molecule that modulates several physiological processes, including signal transmission in the central nervous system. There is evidence supporting NO as a major neurotransmitter involved in motor and emotion/behavior control. We investigated the distribution and morphology of n...

journal_title：Brain research bulletin

authors： Santos-Lobato BL,Del-Bel E,Pittella JE,Tumas V

更新日期：2016-06-01 00:00:00

abstract：:The use of neurons induced from stem cells has been introduced as an effective strategy for promoting peripheral nerve regeneration (PNR). The evolution and role of native denervated Schwann cells (SCs) were often ignored when exploring the mechanisms underlying neural transplantation therapy for PNR. The aim of this ...

journal_title：Brain research bulletin

authors： Zheng Y,Huang C,Liu F,Lin H,Niu Y,Yang X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Evidence concerning the presence or absence of common neuronglia lineages in the postnatal mammalian central nervous system is still a matter of speculation. We address this problem using optic nerve explants, which show an extremely long survival in culture. Morphological, immunocytochemical and immunochemical method...

journal_title：Brain research bulletin

authors： Omlin FX,Riederer BM

更新日期：1992-01-01 00:00:00

abstract：:This work is the second of a series of papers in which we investigated the neurophysiological basis of deep brain stimulation (DBS) clinical efficacy using post-operative local field potential (LFP) recordings from DBS electrodes implanted in the subthalamic nucleus (STN) in patients with Parkinson's disease. We found...

journal_title：Brain research bulletin

authors： Priori A,Ardolino G,Marceglia S,Mrakic-Sposta S,Locatelli M,Tamma F,Rossi L,Foffani G

更新日期：2006-12-11 00:00:00

abstract：:The processing of amyloid precursor protein (APP) to amyloid beta (Aβ) is of great interest to the Alzheimer's disease (AD) field. Decades of research define how APP is altered to form Aβ, and how Aβ generates oligomers, protofibrils, and fibrils. Numerous signaling pathways and changes in cell physiology are known to...

journal_title：Brain research bulletin

authors： Wilkins HM,Swerdlow RH

更新日期：2017-07-01 00:00:00

abstract：:Depression is a brain disorder and there is still only a partial understanding of its underlying pathophysiology. Antidepressant medications with a fast onset have not yet been developed. In addition to the monoaminergic systems, the brain glutaminergic system has been implicated in the etiology of depression. Animal ...

journal_title：Brain research bulletin

authors： Kovačević T,Skelin I,Minuzzi L,Rosa-Neto P,Diksic M

更新日期：2012-03-10 00:00:00

abstract：:Chronic stress, a risk factor for the development of psychiatric disorders, is known to induce alterations in neuronal networks in many brain areas. Previous studies have shown that chronic stress changes the expression of the cannabinoid receptor 1 (CB1) in the brains of adult rats, but neurophysiological consequence...

journal_title：Brain research bulletin

authors： Hu W,Zhang M,Czéh B,Zhang W,Flügge G

更新日期：2011-07-15 00:00:00

abstract：:The transcription factor cAMP response element-binding protein (CREB) promotes target DNA transcription in response to cellular stimulation in brain neurons. Phosphorylation of CREB is regulated by a variety of extracellular and intracellular signals. In this study, protein kinase C (PKC)-regulated CREB phosphorylatio...

journal_title：Brain research bulletin

authors： Mao LM,Tang Q,Wang JQ

更新日期：2007-05-30 00:00:00

abstract：:The non-adenosine nucleoside guanosine (Guo) was demonstrated to decrease quinolinic acid(QA)-induced seizures, spontaneously emerged absence epileptic seizures and lipopolysaccharide(LPS)-evoked induction of absence epileptic seizures suggesting its antiepileptic potential. It was also described previously that intra...

journal_title：Brain research bulletin

authors： Lakatos RK,Dobolyi Á,Todorov MI,Kékesi KA,Juhász G,Aleksza M,Kovács Z

更新日期：2016-06-01 00:00:00

abstract：:We previously reported that a low threshold action of norepinephrine (NE) on the cerebellar circuitry is expressed as an amplification of the inhibitory action of gamma aminobutyric acid (GABA) on Purkinje cell activity. Here we examined the effects of locus coeruleus (LC) stimulation on "off-beam" inhibitions of Purk...

journal_title：Brain research bulletin

authors： Moises HC,Waterhouse BD,Woodward DJ

更新日期：1983-06-01 00:00:00

abstract：:Walker 256 carcinosarcoma cells produce subpleural pulmonary metastases when given intravenously to the Sprague-Dawley rat. The number of metastases increases when the rat is given morphine subsequent to the tumor load. The increase in the number of metastases can be blocked be pretreatment with the opiate antagonist ...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE

更新日期：1986-03-01 00:00:00

abstract：:Recently published work in the rat has shown that: the incidence of electrical coupling, as measured by dye coupling, is decreased from control levels by 8 days of drinking hypertonic saline; an index of circulating testosterone, seminal vesicle weight, is also decreased by 8 days of saline drinking; and both plasma a...

journal_title：Brain research bulletin

authors： Cobbett P,Yang QZ,Hatton GI

更新日期：1987-03-01 00:00:00