Phenylethylamine, a possible link to the antidepressant effects of exercise?

Abstract:

OBJECTIVES:To determine in this pilot study whether aerobic exercise affects phenylacetic acid concentration in the urine. METHODS:Twenty healthy men provided 24 hour urine samples on two consecutive days for the determination of phenylacetic acid levels. Before and during day 1, subjects refrained from physical activity; on day 2 subjects ran on a treadmill at 70% of their maximal heart rate reserve (MHRR) for 30 minutes. RESULTS:The 24 hour mean urinary concentration of phenylacetic acid was increased by 77% after exercise. CONCLUSION:As phenylacetic acid concentration in urine reflects phenylethylamine level, which is known to have antidepressant effects, phenylethylamine may be linked to the therapeutic effects of physical exercise on depression.

journal_name

Br J Sports Med

authors

Szabo A,Billett E,Turner J

doi

10.1136/bjsm.35.5.342

keywords:

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

342-3

issue

5

eissn

0306-3674

issn

1473-0480

journal_volume

35

pub_type

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