Abstract:
UNLABELLED:To examine the value of surfactant protein D and KL-6 as markers for the diagnosis and the severity of interstitial pneumonia caused by measles infection, surfactant protein D, KL-6 and lactic acid dehydrogenase were measured serially in three patients with measles complicated by interstitial pneumonia as compared to ten measles infected patients without interstitial pneumonia. The serum surfactant protein D and KL-6 levels were higher in patients with measles and interstitial pneumonia as compared to those with measles without interstitial pneumonia. In patients with measles and interstitial pneumonia, the respiratory distress and the alveolar-arterial oxygen differences improved after steroid pulse therapy while the serum surfactant protein D level decreased dramatically under the cut-off level and earlier than the KL-6 level. On the contrary, the serum KL-6 level increased transiently and it took longer to decrease below the cut-off level as compared to the pattern observed for serum surfactant protein D. The serum lactic acid dehydrogenase level changes were between those of the surfactant protein D and KL-6 levels. CONCLUSION:Surfactant protein D and KL-6 are easily measured and useful markers for the diagnosis of interstitial pneumonia caused by measles infection. Early decrease of surfactant protein D contrasts with the transient increase of KL-6 levels after prednisolone pulse therapy.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Arai Y,Obinata K,Sato Y,Hisata K,Tadokoro R,Tawa T,Kinoshita Kdoi
10.1007/s004310100763keywords:
subject
Has Abstractpub_date
2001-07-01 00:00:00pages
425-9issue
7eissn
0340-6199issn
1432-1076journal_volume
160pub_type
杂志文章abstract:UNLABELLED:Cleidocranial dysplasia (CCD; MIM 119600) is an autosomal dominant skeletal dysplasia characterised by hypoplastic clavicles, patent fontanelles, short stature, tooth anomalies and other variable skeletal changes. Different mutations of the RUNX2/CBFA1 gene (MIM 600211) have been detected in patients with CC...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-002-0977-x
更新日期:2002-11-01 00:00:00
abstract:UNLABELLED:Human parechoviruses (HPeV) have been recently recognized as important viral agents in paediatric infections. The aims of this study were to investigate the HPeV infection prevalence in infants <1 month in Spain and, secondly, to analyse the clinical and epidemiological characteristics of the infected patien...
journal_title:European journal of pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1007/s00431-015-2566-9
更新日期:2015-11-01 00:00:00
abstract::An 11-year-old boy with chronic granulomatous disease caused by cytochrome b deficiency developed right upper lung lobe aspergillosis. Intracerebral lesions developed on maximum doses of flucytosine and amphotericin B. Treatment with 16 mg/kg oral itraconazole was followed by a dramatic clinical improvement and almost...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01958428
更新日期:1991-05-01 00:00:00
abstract::To evaluate the ambulatory management of ileo-colic intussusception in infants and children, a retrospective study over 3 years of 113 children treated for ileo-colic intussusception in a paediatric emergency department was undertaken with the aim of shortening the length of stay. A total of 113 children aged 10 days ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310051184
更新日期:1999-09-01 00:00:00
abstract::Plasma vitamin E levels were determined serially in preterm infants surviving respiratory distress syndrome (RDS) and in premature infants without RDS (control). Vitamin E intakes of the RDS and control infant group were not significantly different. The results of the study show that preterm infants surviving RDS have...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00446056
更新日期:1986-08-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to determine the effect of low birth weight at term on serum lipoproteins. Lipid and apolipoprotein (apo) contents were investigated in cord sera of small-for-gestational-age (SGA) newborns at term (2290 g +/- 33 g) and compared with those of appropriate-for-gestational-age (AGA...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310050820
更新日期:1998-04-01 00:00:00
abstract::It is not clear if children with high fever are at increased risk for serious bacterial infection (SBI). Our aim was to systematically review if children suffering from high fever are at high risk for SBI. Our data sources were Embase, Medline, and Pubmed; from their inception until the last week of March 2017. The st...
journal_title:European journal of pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00431-018-3098-x
更新日期:2018-03-01 00:00:00
abstract::Newborns are exposed to mechanical and oxidative stress during labor and to relative hyperoxia thereafter during the course of adaptation to the extrauterine conditions. Part of the adaptation mechanism is the rapid degradation of fetal hemoglobin and the oxidation of its heme moiety by heme oxygenases (HOs). Heme oxy...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0375-x
更新日期:2007-10-01 00:00:00
abstract::A girl suffering from marked muscular hypotonia, severe statomotor and mental retardation, bilateral optic atrophy with chorioretinal degeneration, convulsions and a moderate compensated metabolic acidosis is described. Screening for metabolic disorders revealed massive 3-methylglutaconic with 3-methylglutaric aciduri...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442306
更新日期:1985-03-01 00:00:00
abstract:UNLABELLED:The effect of different feeding regimens, notably the use of hydrolysed cow's milk formulas, on the development of allergic reactions and the development of cow's milk protein-IgG antibodies is still disputed. We prospectively compared the development of allergic manifestations and cow's milk protein-IgG ant...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02002723
更新日期:1996-04-01 00:00:00
abstract:UNLABELLED:A retrospective analysis of 218 bunk-bed accidents and a random sample survey with 991 family interviews were performed in order to establish guidelines for bunk-bed accident prevention. Falls from the top bed during sleep (35.1%) or while playing (34.4%) and falling off the ladder (23.2%) are the leading ca...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310051303
更新日期:2000-06-01 00:00:00
abstract:UNLABELLED:Compliance by residents in pediatrics to pediatric resuscitation guidelines is low. In many French faculties, a 1-h traditional lecture is still used to educate medical students about pediatric cardiopulmonary arrest (CPA). We developed an innovative pedagogic course combining a 23-min video and 3-h simulati...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-016-2702-1
更新日期:2016-06-01 00:00:00
abstract::We have investigated four patients from three unrelated families with typical clinical and biochemical features of "late-onset" multiple carboxylase deficiency. All patients suffered from biotinidase deficiency (plasma biotinidase activities 1.4%-3% of normal). Intestinal absorption of biotin, measured in three of the...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00491919
更新日期:1985-05-01 00:00:00
abstract::Nineteen (12 male, 7 female) children, who have received craniospinal irradiation for the treatment of a brain tumour distant from the hypothalamic-pituitary axis, resulting in growth hormone (GH) deficiency (CS-PRGHD), have been treated with GH. Eight have completed growth. Comparison has been made with the growth of...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442471
更新日期:1988-08-01 00:00:00
abstract::An 8-year-old boy with an hepatic form of Wilson disease was treated with oral zinc sulphate as the primary and sole therapy. After 4 months, liver function had dramatically improved, and the parameters characterizing copper metabolism had also normalized. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441526
更新日期:1989-06-01 00:00:00
abstract:INTRODUCTION:Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). OBJECTIVES:Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with C...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0132-1
更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Hypothermia at birth is strongly associated with mortality and morbidity in pre-term infants. BACKGROUND:A local audit showed limited effectiveness of occlusive wrapping in preventing admission hypothermia in very pre-term infants. Self-heating acetate gel mattresses were introduced as a result to prevent...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-009-1113-y
更新日期:2010-07-01 00:00:00
abstract::The development of visual acuity and stereopsis was studied in 321 boys and 340 girls aged between 5 and 10 years. Visual acuity was assessed by the E test and a modified version of the STYCAR test, stereo acuity by the Lang-Stereo test [17]. Both vision tests showed an increase in the median visual acuity between the...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02429046
更新日期:1986-12-01 00:00:00
abstract:UNLABELLED:Adolescents are becoming more independently responsible for their medication regimen; therefore, adolescence is a crucial period to address medication beliefs, as many of the beliefs may persist into adulthood and can impair adherence and willingness to continue a prescribed therapy. Within this study, we ai...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-013-2211-4
更新日期:2014-04-01 00:00:00
abstract::We report a 28-day-old female infant with pertussis presenting as severe acute bronchiolitis with cyanosis. On admission, the patient's symptoms were similar to those of acute bronchiolitis. However, occasional apneic episodes with cyanosis and peripheral lymphocytosis suggested neonatal pertussis and prompted us to e...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-008-0744-8
更新日期:2009-03-01 00:00:00
abstract::Soon after birth a 36-week-gestational age, appropriate for dates, newborn infant developed hyperinsulinaemic hypoglycaemia which responded to diazoxide and glucose infusion. While normoglycaemic, he became increasingly ill with high lactate, pyruvate, and alanine levels. Provocation tests suggested a defect in lactat...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496802
更新日期:1983-12-01 00:00:00
abstract:UNLABELLED:To determine bilirubin-induced neurotoxicity, serial visual evoked potentials (VEPs) of 72 infants with neonatal hyperbilirubinaemia and 22 controls were evaluated and compared in four sessions for 8 weeks after birth. The levels of maximal serum bilirubin were found positively related to the wave latencies ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02079073
更新日期:1995-08-01 00:00:00
abstract::A 15-year-old girl was admitted with a high fever and progressive malaise, vomiting, anorexia and abdominal complaints. She previously had a sore throat and unilateral painful swollen lymph nodes in the neck. Laboratory investigation indicated a bacterial infection. Blood cultures were taken. There was infiltrate in t...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-007-0628-3
更新日期:2008-06-01 00:00:00
abstract::We report here our findings in two Japanese siblings who experienced recurrent bacterial and viral infections since early infancy. Recent symptoms included diarrhoea, conjunctivitis, rashes, headache, sore throat, joint pain, vomiting and vertigo, all similar to those seen in toxic shock syndrome, except for shock. Th...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01956412
更新日期:1994-05-01 00:00:00
abstract::We report on a youngster followed by his paediatrician from birth until 14 years of age for premature beats, most likely of ventricular origin. The sudden death of his sister provoked a re-assessment of his electrocardiograms (ECG), resulting in the diagnosis of Brugada syndrome and the subsequent implantation of a ca...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-006-0150-z
更新日期:2006-08-01 00:00:00
abstract:: ...
journal_title:European journal of pediatrics
pub_type: 评论,信件
doi:10.1007/s00431-018-3252-5
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:Aminoglycoside prescriptions were rarely evaluated in children care facilities. Because of risk of toxicity, these narrow spectrum antibiotics are commonly misused. In this study, we evaluate aminoglycoside prescription and assess the impact of an information campaign on modalities of prescription and monito...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-016-2691-0
更新日期:2016-05-01 00:00:00
abstract::A 4-month-old infant was admitted to the Pediatric Intensive Care Unit with Pneumococcal meningitis. A few hours after admission he developed intractable convulsions that could not be stopped with phenytoin, phenobarbitone and a continuous drip of diazepam. Thiopentone sodium anaesthesia was induced for 24 h terminati...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441663
更新日期:1983-04-01 00:00:00
abstract::We addressed growth of biliary atresia (BA) patients living with native livers between ages 0-6 and effects of post-surgical corticosteroid treatment on growth. Growth charts of 28 BA patients born in Finland between 1987 and 2017 were retrospectively evaluated. Dosage and length of corticosteroid treatment and hydroc...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-018-3302-z
更新日期:2019-03-01 00:00:00
abstract::Our aim was to assess the utility of serum thyroxine and thyroid stimulating hormone performed at 10-14 days of life in diagnosing congenital hypothyroidism (CH) in babies born to mothers with hypothyroidism. This was a retrospective study of all babies born in a tertiary referral centre for neonatology over a 12-mont...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-016-2793-8
更新日期:2016-12-01 00:00:00