Abstract：
:To study the potential use of insects remains as toxicological indicators, we measured morphine in desiccated entomological materials using a radioimmunoassay method (Coat-A-Count Serum Morphine, Dade Behring, France) following enzymatic hydrolysis.First, enzymatic cuticle extraction of morphine (pronase digestion preceded by a 2h incubation with a dithiothreitol solution) was performed on various substrates (Calliphoridae puparial cases and desiccated adults, and desiccated pupae of Dermestidae) which were then tested to identify possible interferences with the radioimmunoassay procedure. This same procedure was performed on puparial cases and desiccated adults of Lucilia sericata (Diptera, Calliphoridae) previously reared on minced meat containing various morphine concentrations. Morphine was detected only in cuticle powder from insects reared on meats containing 100 and 1000mg/kg. Higher concentrations were measured in puparial cases. Rearings on psoas from eight heroin overdose victims confirmed previous experimental results. Remains of necrophagous insects, particularly puparial cases, are often preserved for a long time, and consequently can serve as late alternative specimens for toxicological analysis when suitable tissues are not available.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Bourel B,Tournel G,Hedouin V,Deveaux M,Goff ML,Gosset Ddoi
10.1016/s0379-0738(01)00428-5keywords:
subject
Has Abstractpub_date
2001-08-15 00:00:00pages
127-31issue
1-2eissn
0379-0738issn
1872-6283pii
S0379073801004285journal_volume
120pub_type
杂志文章abstract：:This is a preliminary report on significant alterations in the DNA profile caused by toxic substances which potentially has profound implications for the use of DNA techniques in identification. Acute DNA changes in the globus pallidus of the brain in man caused by carbon monoxide poisoning were detected by DNA profil...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(95)01879-4
更新日期：1996-04-23 00:00:00
abstract：:Urine morphine levels after the consumption of poppy seeds were measured in two separate trials. Maximum levels of approximately 18 micrograms/ml were found using RIA, EMIT-ST and GC methodologies. Positive immunoassay results were seen up to 60 h post-ingestion. Several different lots of seeds from various sources we...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(85)90173-2
更新日期：1985-02-01 00:00:00
abstract：:Forensic investigators commonly interpret bone fracture patterns to estimate the force required to generate that trauma. Unfortunately, these estimates are limited to qualitative values such as "mild", "moderate" or "extreme" force. This work presents a new experimental forensic device developed to simulate blunt- and...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.110123
更新日期：2020-02-01 00:00:00
abstract：:In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the Iberian Peninsula. All the m...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.10.023
更新日期：2007-12-20 00:00:00
abstract：:Timing of fusion of the spheno-occipital synchondrosis (SOS) is correlated with age. Previous research, however, has demonstrated variation in the timing of closure among different global populations. The present study aims to quantify the timing of SOS fusion in Malaysian individuals as visualised in multi-detector c...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.12.046
更新日期：2018-03-01 00:00:00
abstract：:A portable near infrared spectrometer was applied to the presumptive identification of psychotropic drugs based on library searching. Data-treatment methods (mathematical pretreatment and library search algorithm) were examined on the basis of differentiation ability. The optimized mathematical pretreatment was a stan...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.05.020
更新日期：2014-09-01 00:00:00
abstract：:In order to evaluate histological features of freezing damages to human tissue after death, we froze samples of liver and heart tissue to temperatures of -12 degrees C, -28 degrees C and -80 degrees C, and stored them for 24 and 72 h, respectively, at those temperatures. After thawing and routine preparation for histo...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(99)00043-2
更新日期：1999-06-28 00:00:00
abstract：:Downstairs falls frequently occur within domestic environments and are mainly associated with elderly and intoxicated individuals, often feature multiple injuries on various parts of the body. In most cases it is not possible to determine the cause of the fall and/or death solely by means of external examination. In t...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2003.12.016
更新日期：2004-05-10 00:00:00
abstract：:We investigated 40 patients who had died following open heart surgery between January 1990 and May 1992. Between this time, 703 open heart procedures were carried out at the University Medical School of Debrecen, 2nd Department of Surgery's Cardiac Surgery Unit with a mortality rate of 8.3%. We studied each individual...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(96)01896-8
更新日期：1996-05-31 00:00:00
abstract：:The Finnish guidelines for workplace drug testing outlined here represent what is considered the best practice for workplace drug testing to be followed in Finland. The guidelines are based on the act on the protection of privacy in working life (759/2004), the occupational health care act (1383/2001) and the decree o...
journal_title：Forensic science international
pub_type： 指南,杂志文章
doi：10.1016/j.forsciint.2007.03.006
更新日期：2008-01-30 00:00:00
abstract：:A novel 39-plex typing system for single nucleotide polymorphisms (SNPs) has been developed. This multiplex approach has the advantage of being able to type 38 autosomal SNPs and one sex-discriminating base exchange site on the X and Y chromosomes rapidly and simultaneously. The SNP loci on the autosomes, which we exa...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.03.005
更新日期：2004-08-11 00:00:00
abstract：:Cannabis cultivation in order to produce drugs is forbidden in Switzerland. Thus, law enforcement authorities regularly ask forensic laboratories to determinate cannabis plant's chemotype from seized material in order to ascertain that the plantation is legal or not. As required by the EU official analysis protocol th...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.03.034
更新日期：2010-07-15 00:00:00
abstract：:Fatty acid ethyl esters (FAEE) are direct metabolites of ethanol and have been shown to be suitable markers for the evaluation of alcohol consumption. Previous research has suggested that the regular use of alcohol containing cosmetic products can influence the concentration of FAEE detected in hair. In this study we ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.12.002
更新日期：2018-02-01 00:00:00
abstract：:We report a possibly first forensic autopsy case of death following a spontaneous recovery from cardiopulmonary arrest (CPA) after clinical declaration of death: 'Lazarus phenomenon'. A 65-year-old male with congenital deafness and dumbness was found unconscious in his room at a public home. During pre-hospital and cl...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00107-x
更新日期：2002-06-25 00:00:00
abstract：:Venlafaxine is an extensively used antidepressant drug; it is considered to be quite safe and only a few pure cases of fatal poisoning have been reported. Here we describe a fatal case of venlafaxine self-poisoning including detailed tissue distribution of the drug and its metabolite O-desmethylvenlafaxine and the exa...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.07.011
更新日期：2014-09-01 00:00:00
abstract：:The value of complex analyses of body injuries and clothing has been proven by practice. The purpose of presented study is to discuss what additional information can be obtained during investigations of clothes in the area of injury. A case study, in which results of visual and stereomicroscopic morphological analysis...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.09.023
更新日期：2004-12-02 00:00:00
abstract：:Characterization and assessment of inks on sensitive documents for absolute/relative age determination is the challenging forensic problem in spite of practical difficulties. Tagging of ballpoint pen ink with suitable taggant(s) is a unique method to come out with definitive inferences on the detection of forgery in d...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.05.037
更新日期：2006-05-25 00:00:00
abstract：:The abuse or misuse of forged erectile-dysfunction drugs, containing phosphodiesterase type 5 inhibitors (e.g. sildenafil), is a serious issue globally. Therefore, the detection of sildenafil and related active analogues in counterfeit pharmaceuticals or the differentiation between counterfeit and authentic drugs has ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.08.016
更新日期：2015-12-01 00:00:00
abstract：:The Bavarian State Bureau of Investigation in Munich has the exclusive responsibility for investigation of criminal acts. One considerable expertise is that of hair analysis. According to the legal system in Germany, there is a special interest when some clients' hair tested positive for illicit drugs. An accused with...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(99)00161-9
更新日期：2000-01-10 00:00:00
abstract：:The dead body of a 44-year-old woman, previously known for depression and alcoholism, has been discovered at her place of residence by her husband. A forensic autopsy has been carried out. The results indicated unspecific histological lesions (alveolar oedema, liver steatosis and interstitial nephritis) but did not re...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2008.03.003
更新日期：2008-07-04 00:00:00
abstract：:Cyanide is a powerful chemical asphyxiant found in some forensic cases following voluntary (suicide) or involuntary ingestion (fire, accidental exposure). A quantification method for cyanide that is specifically suited to post-mortem forensic purposes was developed. Determination was performed by headspace gas chromat...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.06.017
更新日期：2012-10-10 00:00:00
abstract：:A sample of 166 normal adult males and females was taken from different colleges of Assiut representing those living in upper Egypt. Each subject has been studied for measurements of stature (S), hand length (HL) and hand breadth (HB). The data were statistically analysed in order to assess the relationship between st...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(90)90304-h
更新日期：1990-07-01 00:00:00
abstract：:Cranial suture closure has been recognized for over a century as a useful trait for age estimation. Although this indicator has become a standard feature of age assessment protocols in skeletal remains, serious questions have been raised about its reliability. This article attempts to provide a comprehensive review of...
journal_title：Forensic science international
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.forsciint.2019.110111
更新日期：2020-02-01 00:00:00
abstract：:Previous studies have indicated that metal particles remain on bone after sharp force injury or gunshot and that their detection by scanning electron microscopy with energy dispersive X-ray spectrometry (SEM-EDS) could greatly help in tool identification. However, the presence of metal particles on bone surfaces in th...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.08.007
更新日期：2012-11-30 00:00:00
abstract：:Bacterial genotyping can be used for crime scene investigations and contribute to the attribution of biological attacks for microbial forensics. PyroMark ID Pyrosequencer as an accurate detection platform for single nucleotide polymorphisms (SNPs) has been applied to identify and resolve microorganisms involved in clo...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.11.004
更新日期：2015-01-01 00:00:00
abstract：:Tooth formation is widely used to assess maturity and to predict age. Within clinical dentistry, such information aids in diagnosis and treatment planning. Numerous methods exist that allow either the prediction of age or an assessment of maturation. One widely used method was first described in 1973 by Demirjian et a...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2007.04.228
更新日期：2008-02-25 00:00:00
abstract：:The worldwide spread of illegal sexual enhancement products is posing a threat to public health. The aim of this study was to investigate illegal products claiming to be effective in improving sexual performance through the online or offline markets between 2014 and 2017; these products include foods, dietary suppleme...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.02.014
更新日期：2019-05-01 00:00:00
abstract：:Tryptase is a neutral protease of human mast cells, and an important indicator of mast cell activation and degranulation in anaphylactic events. The elevation of serum mast cell tryptase (SMCT) is used for postmortem diagnosis of anaphylaxis. We have quantified the SMCT levels of 122 forensic autopsy cases with variou...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.06.011
更新日期：2005-04-20 00:00:00
abstract：:Seven cases and a quality assurance test are presented. In these cases, fibres or textiles submitted for investigation were analysed by HPLC-DAD-MS to identify the dyes present. The cases presented illustrate that it is possible to identify textile dyes in fibre traces recovered for forensic analysis. The results show...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.07.026
更新日期：2017-09-01 00:00:00
abstract：:Doxylamine is an antihistamine of the ethanolamine class. It is used primarily as a sleep-inducing agent. Only a few reports can be found in the literature about lethal intoxications with doxylamine, but many with combined intoxications. Doxylamine is, aside from diphenhydramine, the only chemically defined active ing...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/s0379-0738(00)00393-5
更新日期：2001-06-01 00:00:00
