Abstract:
:Doxylamine is an antihistamine of the ethanolamine class. It is used primarily as a sleep-inducing agent. Only a few reports can be found in the literature about lethal intoxications with doxylamine, but many with combined intoxications. Doxylamine is, aside from diphenhydramine, the only chemically defined active ingredient in some sleeping medications which is available without a prescription in the Federal Republic of Germany. Two cases of doxylamine poisoning are presented, in which high doxylamine concentrations were found in the blood and organs.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Bockholdt B,Klug E,Schneider Vdoi
10.1016/s0379-0738(00)00393-5keywords:
subject
Has Abstractpub_date
2001-06-01 00:00:00pages
138-40issue
1eissn
0379-0738issn
1872-6283pii
S0379073800003935journal_volume
119pub_type
杂志文章,评审abstract::We have developed a triplex PCR method for D3S1359, HumTH01 and HumTPO tetranucleotide loci and a duplex PCR method for HumFES/FPS and HumvWA31A tetranucleotide loci using high resolution polyacrylamide gel electrophoresis and silver staining. The methods were evaluated for paternity testing and individual identificat...
journal_title:Forensic science international
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abstract::A very serious case of DFSA (drug facilitated sexual assault) is presented, in which a six-year-old girl died following sedation with γ-hydroxybutyric acid (GHB). She had been sexually abused by a relative. Samples of cardiac blood, bile, vitreous humour, liver, kidney, brain tissues and hair were analysed by a LC-MS/...
journal_title:Forensic science international
pub_type: 杂志文章
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abstract::The aim of the present study was to investigate stress gene expression in cultured primary fibroblasts established from Achilles tendons collected during autopsies from sudden infant death syndrome (SIDS) cases, and age-matched controls (infants dying in a traumatic event). Expression of 4 stress responsive genes, HSP...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.06.003
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abstract::The authors have proposed a quantitative method for assessing weight of evidence in the case where a fingermark from a crime scene is compared with a set of control prints from the ten fingers of a suspect. The approach is based on the notion of calculating a Likelihood Ratio (LR) that addresses a pair of propositions...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.08.008
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abstract::A fraction of SIDS cases have death delayed by successful CPR, yet they have not been compared to SIDS cases which were found dead or not successfully resuscitated. Our aims were to: (1) determine the percent of SIDS cases in the San Diego SIDS Research Project database for whom death was delayed by CPR and subsequent...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.09.009
更新日期:2008-04-07 00:00:00
abstract::Human hair is among the most common kind of evidence secured at crime scenes. Although DNA analysis through STR-typing is possible in principle, it is not very promising for telogenic hair or single hairs. For the mixed traces frequently found in practice, composed of different hair from an unknown number of individua...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.12.018
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abstract::Injuries caused by traffic accidents can be complex and extensive. Due to the highly dynamic course of actions, reconstructive questions may be challenging to investigators. Differentiation of a single collision from an overrun is a central question. We hypothesized that the existence of spine fractures such as spinou...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.01.013
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abstract::In the process of questioned document examination, the discrimination of inkjet printing inks is becoming more necessary due to increasingly frequent counterfeiting of documents printed by inkjet printers. Therefore, a method based on micellar electrophoretic capillary chromatography (MECC) has been developed and appl...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.05.017
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abstract::The analysis of ethyl glucuronide (EtG) in hair is a powerful tool for chronic alcohol abuse control because of the typical wide detection window of the hair matrix and due to the possibility of segmentation, allowing evaluation of alcohol consumption in different periods. Additionally, EtG in hair is often the only d...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2009.07.023
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abstract::Reconstruction of ripped-up documents can be a very time-consuming task for forensic experts. Currently, this task is often carried out using various homespun or loosely defined procedures. Under the main assumption that a (partially) ordered set of fragments can be recovered, we propose and discuss a more formal anal...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.07.013
更新日期:2008-04-07 00:00:00
abstract::A 76-year-old male with a previous history of heart arrhythmia and decompensation was treated for a complicated thoraco-abdominal trauma. Accidentally, a pleural drain was inserted in his heart through the ventricular septum, perforating the left ventricle, the drain tip being buried in its posterior wall. This injury...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(81)90186-9
更新日期:1981-01-01 00:00:00
abstract::Allele frequencies for the 19 STRs loci, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, CSF1PO, F13A01, F13B, FESFPS, FGA, LPL, Penta D, Penta E, TH01, TPOX and VWA were obtained from a sample of 203-1188 unrelated individuals living in the area of south-east Poland. ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2003.10.001
更新日期:2004-01-06 00:00:00
abstract::Craniofacial reconstruction (CFR) is used to recreate a likeness of original facial appearance for an unidentified skull; this technique has been applied in both forensics and archeology. Many CFR techniques rely on the average facial soft tissue thickness (FSTT) of anatomical landmarks, related to ethnicity, age, sex...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.07.017
更新日期:2016-09-01 00:00:00
abstract::Among all the improvised explosive devices (IEDs) known, pipe bombs are one of the most popular devices used by terrorists. They are simple to use, easy to construct and materials are readily available. For this IED, fragmentation is the primary injury mechanism, which makes them a desirable weapon for terrorists aimi...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.110034
更新日期:2020-01-01 00:00:00
abstract::Synchrotron infrared chemical imaging was employed to examine and assess the extent of interlayer component migration within multilayer automotive paint samples, with a particular emphasis on the cross-linking additive melamine. Two dimensional infrared chemical images revealed that melamine consistently diffuses in s...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.01.032
更新日期:2013-05-10 00:00:00
abstract::Material and failure analysis techniques are key tools for determining causation in case of explosive and bursting accident result from material and process defect of product in the field of forensic science. The boiler rupture generated by defect of the welding division, corrosion, overheating and degradation of the ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.07.036
更新日期:2017-09-01 00:00:00
abstract::One of the major challenges in the near future is the identification of genes that affect the metabolism of different drugs. Large scale association studies that utilise single nucleotide polymorphisms (SNPs) have been considered a valuable tool for this purpose. CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 were found t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.10.004
更新日期:2011-04-15 00:00:00
abstract::The spreading of bloodstains on matt, vinyl silk and gloss painted surfaces, following both perpendicular and non-perpendicular impact, has been studied with a view to understanding whether surface-specific properties affect the size and shape of the final stain. In all cases the dimensions of the stains on the roughe...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.03.044
更新日期:2013-06-10 00:00:00
abstract::The prosecution of those socially irresponsible individuals who drive when they have had too much to drink - in that their breath, blood or urine alcohol level exceeds the prescribed legal limit - has been standard practice since October 1967. The forensic analysis of whichever type of specimen is taken from the suspe...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.09.030
更新日期:2018-12-01 00:00:00
abstract::A high-performance liquid chromatography-tandem mass spectrometry (LC/MS/MS) technique was developed for the simultaneous determination of five non-steroidal anti-inflammatory oxicam drugs (ampiroxicam, tenoxicam, piroxicam, meloxicam and lornoxicam) in human plasma. These five oxicam drugs and isoxicam (internal stan...
journal_title:Forensic science international
pub_type: 杂志文章
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abstract::The examination of damage to a paper towel, an item of evidence in a murder case, is described. Simulations performed with selected tools and the observation of the lacerations present on the towel permitted to infer that they were originated by cleaning of a pointed and sharp implement. Some marks, considered charact...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.04.078
更新日期:2005-03-10 00:00:00
abstract::Identification in forensic anthropology and the definition of a biological profile in bioarchaeology are essential to each of those fields and use the same methodologies. Sex, age, stature and ancestry can be conclusive or dispensable, depending on the field. The Fordisc(®) 3.0 computer program was developed to aid in...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.03.011
更新日期:2011-05-20 00:00:00
abstract::In this work, a case of deliberate self-poisoning is presented. A 14-year-old girl suddenly died during one of the several hospitalizations. Abdominal computer tomography showed a large number of metallic particles in the large intestine. Analysis of blood and internal organs for mercury and other toxic metals carried...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.02.015
更新日期:2014-04-01 00:00:00
abstract::Hypertension is a growing medical concern in the United States. With the number of Americans suffering from hypertension increasing, the use of antihypertensives such as beta-blockers is increasing as well. In fact, three beta-blockers - atenolol, metoprolol and propranolol - were among the 200 most prescribed medicat...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.01.001
更新日期:2006-01-27 00:00:00
abstract::Previous research has raised the possibility that automotive brake pads can produce particles that are both compositionally and morphologically similar to gunshot residue (GSR). These studies, published in the early 2000s, coincided with the reduction or removal of unnecessary sources of lead from the automotive indus...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.11.024
更新日期:2017-01-01 00:00:00
abstract::Cholesterol levels in the median nerve were studied at various post-mortem intervals (PMIs). Single median nerve samples were collected from the wrists of 36 subjects during forensic autopsies of subjects with known circumstances and times of death. Although the absolute values varied, increments in cholesterol concen...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.01.004
更新日期:2016-08-01 00:00:00
abstract::An accurate and reproducible technique was employed for measurement of water content (RBCH2O) and potassium concentration (RBCK) in rat erythrocytes post mortem. Coefficients of variation for determination of RBCH2O and RBCK, as estimated from the results of duplicate analyses (n = 36), were 1.21% and 1.17%, respectiv...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(88)90014-x
更新日期:1988-07-01 00:00:00
abstract::Teeth are recently drawing attention for their potential as biological modeling investigation samples due to their ability to be collected and their slow substance metabolism. There is no active metabolism of elements after the completion of dentin. Dentin is surrounded by enamel and cementum, and is not affected by t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.11.012
更新日期:2012-06-10 00:00:00
abstract::When inspecting the scene the circumstances under which a body is found and the findings on the body surface may give first clues to premortal drug abuse. Besides fresh and/or old injection marks tattoos, underweight and signs of physical neglect, especially after long-term abuse, are mentioned in literature. The inci...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00587-4
更新日期:2001-12-27 00:00:00
abstract::Carbofuran is a broad spectrum carbamate insecticide which inhibits cholinesterase. In the recent past several carbofuran related homicide and suicide cases were reported in Sri Lanka. The concentration of carbofuran found in blood, bile and/or tissues in eight fatal cases were presented in this paper. Liquid-liquid e...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.10.039
更新日期:2013-04-10 00:00:00